• Title/Summary/Keyword: Group Difference

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Effects of Partial Cervus elaphus Linne' Extract on Antitumoral Immune Response in Melanoma-induced Mice (부위별(部位別) 녹용(鹿茸)이 흑색종(黑色腫) 유발(誘發) 생쥐의 종양억제(腫瘍抑制)와 면역기능(免疫機能)에 미치는 영향(影響))

  • Oh Ha-Souk;Kim Jang-Hyun
    • The Journal of Pediatrics of Korean Medicine
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    • v.14 no.1
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    • pp.39-78
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    • 2000
  • Introduction: In order to investigate the effects of partial Cervus elaphus Linne' extract on antitumoral immunological, a group of mice are melanoma-induced and observed reponses in terms of the number of lymphocyte, CD4+ count, CD8+ count, CD4+/CD8+ ratio in blood and spleen, change in body weight, melanoma weight, spleen index, NK cell activity and productivity of IL-2 in each mouse Methodology: Male C57BL/6 mice were chosen as an experimental object and were divided into 5 groups randomly selection. The normal group did not receive any induction. The control group was treated with normal saline in melanoma-induced' mice. Sample I group induced the upper part of Cervus elaphus Linne' extract in melanoma-induced mice. Sample II group was induced the middle part of Cervus elaphus Linne' extract in melanoma-induced mice. Sample III group was induced the lower part of Cervus elaphus Linne' extract in melanoma-induced mice. The dosage of medication was 0.2cc daily for 14days. Results: 1. There was a significant difference in the number of lymphocyte in spleen in the sample I (upper part of Cervus elaphus Linne' extract induced) and the sample II (middle part of Cervus elaphus Linne' extract induced) compared to the control group and the sample III (lower part of Cervus elaphus Linne' extract induced). On the other hand, no significant difference was observed in the number of lymphocyte in blood in the control group and all sample groups. 2. In the CD4+ T cell ratio in blood, all three sample groups showed differences compared to the control group, though there was no significant difference between sample groups. In the CD4+ T cell ratio in spleen, there was a difference between the sample I and the control group, while the sample II and the sample III had significant difference to the control group. And also, it has been observed there were differences between the sample I and the other samples. 3. In the CD8+ T cell ratio in spleen, all three sample groups showed significant differences compared to the control group, while there was no difference between groups in the ratio in blood. 4. In the CD4+/CD8+ T cell ratio in blood, the sample I showed a significant difference compared to the control group, while the sample 1I and sample III showed differences compared to the control group. In the CD4+/CD8+ T cell ratio in spleen, all three samples showed a significant difference compared to the control group, when the sample I had a difference to the other sample groups. 5. The spleen index of the sample I and the sample II showed a significant difference compared to the sample III and the control group. In comparison between the sample groups, the sample I and the sample II showed a significant difference to the sample III. 6. In terms of the change in body weight and melanoma weight, all three sample groups showed a significant difference compared to the control group, while the comparison between the sample groups showed the sample and the sample II had a significant difference to the sample Ⅲ. 7. In comparison of NK cell activity, the sample I had a difference compared to the other groups when the effector to target cell ratio was 2.5:1. With the ratio of 5:1, the sample I and sample II showed significant differences compared to the control group, while the sample Ⅲ showed a difference. When the effector to target cell ratio was 10:1, there was no difference between groups. 8. In the productivity of IL-2, all three sample groups showed significant differences compared to the control group. In comparison between sample groups, there were significant differences between each sample groups in order of the sample I , the sample II and the sample Ⅲ. Conclusion: As one can witness from the above results, administration of partial Cervus elaphus Linne extract played important role in antitumoral immune response in melanoma-induced mice, and it could be suggested that sample I and sample II groups have prominent antitumoral immune effect.

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The Effects of Solution-Focused Group Counseling on the Stress Response and Coping Strategies in the Delinquent Juveniles (해결중심 집단상담이 비행청소년의 스트레스 반응과 대처방식에 미치는 효과)

  • 고미자;유숙자;김양곤
    • Journal of Korean Academy of Nursing
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    • v.33 no.3
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    • pp.440-450
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    • 2003
  • Purpose: This study was conducted to examine the effects of solution-focused group counseling on the general stress, stress response and coping in the delinquent juveniles. Method: The subjects consisted of a convenience samlple of 60 delinquent juveniles who had been placed under probation in Kwang-ju, and recruited from Oct., 2000 to Dec., 2000. Solution-focused group counseling was conducted for the experimental group once a week for 120 to 180 minutes for 6 week. The control group received no group session. For both groups the level of general stress, stress response and coping were measured before and after the experiment. Result: General stress significantly decreased in the experimental group and increased in the control group, but showed no significant difference between the two groups. Stress response decreased significantly in the experimental group and increased in the control group, but showed no significant difference between the two groups. The problem-focused coping significantly increased in the experimental group and decreased in the control group, and showed a significant difference between the two groups. The emotion-focused coping significantly decreased in the experimental group and increased in the control group, and showed no significant difference between the two groups. Conclusion: This study showed that solution-focused group-counselling has a positive effect on variables like the general stress, stress response, emotion-focused coping and problem-focused coping. Further study needs to be conducted to verify results.

The Effect on Multiplicative thinking and Multiplicative ability by the Instruction of Modeling Problem Situations (문제 장면의 모델화를 통한 수업이 곱셈적 사고력과 곱셈 능력 신장에 미치는 영향)

  • 남승인;서찬숙
    • Education of Primary School Mathematics
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    • v.8 no.1
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    • pp.33-50
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    • 2004
  • This study is intended to investigate the effect on the development of multiplicative thinking and multiplicative ability by teaching repeated addition, rate, comparison, area-array, and combination problems. Two research questions are established: first, is there any difference of multiplicative thinking between the experimental group(the modeling of problem situation learning group) and the control group(the traditional learning group)\ulcorner Second, is there any difference of multiplicative ability between the experimental group and the control group\ulcorner The treatment process for the experimental group is based on modeling problem situations for nine lesson periods. In order to answer the research questions the chi-square analysis was used for the first research question and the t-test was used for the second one. The findings are summarized as follows: there is no significant difference of multiplicative thinking be1ween the experimental and the control group but there is significant difference of multiplicative ability.

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The Comparative Study of Tinnitus Patients and Healthy Volunteers by DSOM (한방 진단 시스템(DSOM)를 통한 이명(耳鳴) 환자와 건강대조군의 변증 비교분석)

  • Kim, Mi-Bo;Byin, Seok-Mi;Shin, Sang-Ho;Ko, Woo-Shin;Yoon, Hwa-Jung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.21 no.3
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    • pp.166-183
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    • 2008
  • Objective : The purpose of this study is to investigate the difference of pathogenesis between tinnitus patients group and healthy volunteers group by using DSOM (Diagnostic system of Oriental Medicine). Methods : Patients group is consisted of people who do not have any disorder except tinnitus, and healthy volunteers group is consisted of people who do not have any special symptom and past history. DSOM was used for pathogenesis investigation of these two groups. Results : There were significant differences between volunteers group and patients group in blood (血虛), dampness (濕), phlegm (痰) (p<0.05), In gender of patients group, deficiency of blood (血虛) was shown with female group statistically more than male group (p<0.05). On the other hand, with volunteers group, there was negligible difference between male and female. In age (over and below 50years), noticeable deficiency of blood (血虛) was shown in patients group. Especially, the old people who are over 50 years showed more deficiency of blood (血虛) than younger group (under 50 years) (p<0.05). With volunteers group, there was only negligible difference. Conclusion : This result showed definite difference in the pathogenesis between tinnitus patiensts group and healthy volunteers group.

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A comparative study on the cardiovascular function response to maximal exercise of chronic low back pain patients and normal group (최대운동부하시 정상인과 만성요통환자의 심폐계 반응에 대한 비교연구)

  • Um Ki-Mai;Kim Gun-Do;Hwang Myoung-Hoon
    • The Journal of Korean Physical Therapy
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    • v.12 no.3
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    • pp.379-386
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    • 2000
  • This study is aimed to determine the cardiovascular function response to maximal exercise of chronic low back pain patients(N=13) and normal group(N=13). by using BRUCE PROTOCOL, subjects underwent tredmill exercise test. Their cardiovascular function responses during rest and after maximal exercise were compared The responses were analyzed using t-test for SPSS 7.0 program. The Cardiovascular function variables employed at rest time(Vo2, HR. Vo2/kg, VE, Vco2.) and all out time(Vo2peak. HRpeak, Vo2peak/kg, VEpeak. Vco2peak). Result show that : 1 There was no significant difference in Vo2 between chronic low back pain patients and normal group at rest time. However significant difference in Volpeak was observed after maximal exercise( p<.05). 2. There was no significant difference in HR between chronic low back pain patients and normal group at rest time. No significant difference in HRpeak likewise observed. 3. There was no significant difference in Vo2/kg between chronic low back pain patients and normal group at rest time. However significant difference in Vo2peak/kg was observed after maximal exercise load(p<.05). 4. There was no significance in VE between chronic low bark pain patients and normal group at rest time. However significant difference in VEpeak observed after maximal exercise load(p<.05).

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Acoustic Features of Oral Vowels in the Esophagus Speakers (식도음성의 모음종류에 따른 음향학적 특성)

  • Yun, Eunmi;Mok, Eunhee;Minh, Phan huu Ngoc;Hong, Kihwan
    • Phonetics and Speech Sciences
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    • v.7 no.4
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    • pp.85-92
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    • 2015
  • This study aimed to establish characteristics related to voice and speech through the natural base frequency analysis of esophagus vocalization. In the study, 8 subjects were selected for esophagus vocals, and 10 other subjects were selected for a control group. MDVP(Multi-dimensional Voice Program, Model 4800, USA, 2001), Multi Speech(Model 3700, Kaypantax, USA, 2008) were used as experiment equipment. The speech samples selected for evaluation were vowels and sentences (both declarative and interrogative). For acoustic analysis, the intonation form of fo, jitter, energy, shimmer, HNR, and intonation patterns of the speech sample were measured. The results were as follows: First, the natural intrinsic frequency of extended vowels in the esophagus vocal group was lower than the frequency in the normal vocal group. In particular, the intrinsic frequency difference for high vowel /i/ was much greater than the frequency difference for low vowel /a/. Second, the jitter values of the esophagus vocal group were higher than the control group. In particular, there was a large difference between the jitter values for /a/ and /i/, with the jitter values being highest for /i/. Third, there was no significant difference in vocal strength between the esophagus vocal patient group and the control group. Fourth, the shimmer values of the voices in the esophagus vocal group were higher than shimmer values in the control group. In particular, there was a large difference in shimmer values for low vowel /a/. Fifth, the HNR values of the esophagus vocal group were showed significantly lower than the control group. In particular, the largest difference in HNR values between the two groups was for high vowel /i/. Sixth, the pitch contours of interrogative and declarative sentences of the esophagus vocal patient group showed a different form or only had with small differences compared to the pitch contours of the normal vocal group, thus presenting an inconsistent pattern.

Vowel length difference before voiced/voiceless consonants in English and Korean

  • Moon, Seung-Jae
    • Phonetics and Speech Sciences
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    • v.9 no.4
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    • pp.35-41
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    • 2017
  • The existence and the extent of vowel length difference before voiced/voiceless consonants in English and Korean are examined in three groups: (1) Korean-speaking Americans (group A), (2) immigrants who moved to the U.S. in their early teens (group I), and (3) Koreans who have been in the U.S. for less than 3 years (group K). 14 subjects were recorded reading 10 English and 10 Korean sentences. The results show that the three groups exhibit different patterns of the vowel length difference: Group A shows a very strong tendency of vowel lengthening before voiced consonants in both English and Korean, while Group I shows less degree of vowel lengthening, and Group K shows almost no tendency of vowel length difference in both languages. This strongly suggests that, (1) unlike English, Korean does not have the vowel length difference depending on the following consonants, and (2) the vowel lengthening effect observed in Korean (L2) speech in group A may be the result of transfer of the phonetic trait acquired in English (L1). It also implies that, in teaching pronunciation, some facts such as the vowel length difference cannot be expected to be acquired automatically for the learners of English, but have to be taught explicitly.

Effect of Functional Recovery for the Functional FES upon Chronic Stroke Patients with Shoulder Subluxation (어깨관절 아탈구가 있는 만성 뇌졸중환자에게 기능적 전기자극 치료가 기능회복에 미치는 효과)

  • Hwang, Ryong;Kim, Chan-Mun
    • Journal of Korean Physical Therapy Science
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    • v.16 no.4
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    • pp.75-81
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    • 2009
  • Background: The purpose of this study was to confirm whether surface FES was effective in the function of chronic stroke patients' affected shoulder and whether FES influenced their functional abilities in ADL, as well. Method: the subjects were inpatients at a general hospital in Gyeonggi-Do, Korea and had been diagnosed as a sub-luxation in their affected shoulder. They were 26 and were separated to an experimental group and a control group, in equal number. Both groups had gotten an exercise treatment for 6 weeks. The control group didn't get any FES as opposed to the experimental group. Result: in the experimental group there was no statistical significant difference in the vertical space and the joint space, even though the space was reduced. In the control group, there was no statistical significant difference, either. Moreover, each space of their shoulders was increased. In the range of motion of each group, there was no statistical significant difference. In functional independent ability, there was a significant difference in an experimental group. In contrast, there was no difference in a control group. Conclusion: this result suggests that FES should be effective in the sub-luxation of the patients' affected shoulder and the range of motion of their shoulders. On the other hand, compared to the previous items, FES was quite effective in the functional improvement.

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Effect of CAI on Home Economics Class of Middle School25 (CAI 수업 형태가 중학교 가정 교과의 학습에 미치는 효과)

  • 임현아;조필교
    • Journal of Korean Home Economics Education Association
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    • v.8 no.1
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    • pp.51-57
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    • 1996
  • The purpose of this study were to examine the difference of the effect of CAI and students’attitude to Home Economics Class through CAI. 120 girl students of the first year were chosen at B middle school in Daegu. Among them each 30 students were classified into 4 groups; High Intelligence group/Individual learning pattern, High Intelligence group/Small group learning pattern, Low Intelligence group/Individual learning pattern, Low Intelligence group/Small group learning pattern. The task of learning was “management of washing”Unit of the second grade. The data were processed with Cronbach’s ${\alpha}$, t-test, ANOVA by SPSS/PC(sup)+. The research findings are as follows: 1. In the verification of CAI Learning effect according to student group pattern, there is no difference between Individual learning pattern and Small group learning pattern in Achivement and Retention of learning. 2. In the verification of CAI Learning effect according to student intelligence level, there is no difference between High Intelligence group and Low Intelligence group in Achivement and Retention of learning. 3. The result of students’attitude to Home Economics Class verificated is an follows. (1) Individual learning pattern is more attensive than Small group learning pattern, but there is no difference in Intelligence level. (2) Low Intelligence group is more positive than High Intelligence group, and Small group learning pattern is more positive than Individual learning pattern in a view of Home Economics Class after using CAI.

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Effects of White Noises on Gait Ability of Hemiplegic Patients during Circuit Balance Training

  • Jang, Na-Young;Kim, Gi-Do;Kim, Bo-Kyoung;Kim, Eun-Hee;Koo, Ja-Pung;Shin, Hee-Joon;Choi, Seok-Joo;Choi, Wan-Suk
    • Journal of International Academy of Physical Therapy Research
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    • v.3 no.1
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    • pp.370-377
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    • 2012
  • This study examines the effects of different environments on the application of hemiplegia patients circuit balance training. Group 1 performed circuit balance training without any auditory intervention Group 2 performed training in noiseless environments and Group 3 performed training in white noise environments. First, among lower extremity muscular strength evaluation items, maximum activity time(MAT) was not significantly different(p>.05). Maximum muscle strength(MMS) increased significantly in Group 3(p<.01), there was no significant difference in MMS among the groups. Average muscle strength(AMS) indexes also significantly increased in Group 3(p<.01), there was no significant difference in AMS among the groups. Second, among balancing ability evaluation items, Berg's balance scale(BBS) scores significantly increased in all groups(p<.05), BBS scores were significantly difference among the groups. Based on the results, Group 1, 2 and Group 1, 3 showed significant increases (p<.05). Functional reach test(FRT) values significantly increased in Group 2, 3(p<.05), and there was no significant difference in FRT values among the groups. Timed up and go(TUG) test values significantly decreased in Group 2, 3(p<.05), and there was no significant difference in TUG test values among the groups. Third, among walking speed evaluation items, the time required to walk 10m significantly decreased in all groups(p<.05), and there was no significant difference in the values among the groups. Average walking speeds showed significant increases in Group 1, 3(p<.05), and there was no significant difference in the values among the groups. Based on the results of this study, noise environments should be improved by either considering auditory interventions and noiseless environments, or by ensuring that white noise environments facilitate the enhancement of balancing ability.