• Journal of Life Science
• /
• v.9 no.2
• /
• pp.194-200
• /
• 1999

Grinding aid is a necessary unit operation when the raw materials are handled in solid form, and the purpose is to improve the bioavailability by reducing the particle size. For the particle design of pefloxacin, the dry planetary ball-mill was used. With the drying process, 330 g of zirconia ball with its size of 2 mm in diameter and 10 g of pefloxacin were transferred to the pot and mixed well. The mixture was ground at 112 rpm (60 Hz) for 15, 30, and 60 min, respectively. The most satisfactory grinding products were generated at 15 min of grinding time for their particle size. The volume mean diameter $\X_50$ of the grinding products was 2.97 $\mu$m. X-ray diffraction (XRD), differential scanning calorimeter (DSC), and infrared spectroscopy (IR) patterns were relatively unchanged before pulverizing pefloxacin and in the progress of grinding. Thus, these results suggest that this pulverizing method can be used for grinding products without evident effect on stability of the drug pefloxacin. Dissolution test was carried out to set up the optimal detective condition against residual antibacteria of fish by HPLC. The grinding pefloxacin for 15 min is most effective in dissolution test.

• Transactions of the Korean Society of Mechanical Engineers
• /
• v.14 no.6
• /
• pp.1533-1541
• /
• 1990

Cubic boron nitride (CBN) is known the second hardest material followed diamond and was provided industry as an abrasive grain in the late 1960's. Since the introduction of CBN, a large amount of research has been carried out to determine the best application condition for grinding operation. Despite the advantages in its characteristics, CBN has not yet gained full acceptance as more excellent abrasive grain than traditional one. The reason for this state is that the surface roughness ground by CBN is worse than by traditional one and dressing and truing is very difficult. This led user's resistance to the use of CBN as an abrasive grain. Present study is to investigate the cause of lower surface roughness ground by CBN single crystal abrasive grain comparing with traditional one.

• Journal of the Korean Society for Railway
• /
• v.11 no.3
• /
• pp.272-279
• /
• 2008

The importance of maintenance of rail surface defects is increasing more according to the KTX operation. That is because during high speed operation of rolling stock, rail surface defects may cause shortened fatigue life of rail, acceleration of track degradation and reduced ride comfort. The paper was intended to study the establishment of rail grinding criteria of high-speed railway lines considering the KTX operation circumstances. For this, the specimens of UIC 60 rail on Kyeong-Bu high-speed operation lines were collected and they were tested for metallographic structure and measured for the hardness. As the factors affecting RCF causing the defects of rail surface, passing tonnage, running speed and track condition are considered.

• Journal of Life Science
• /
• v.9 no.3
• /
• pp.241-247
• /
• 1999

Antibiotics have been routinely used to control the disease of farm-raised animals in the aquaculture facilities without any criterion based on a pharmacokinetic study. This lack of information on the effective usage of antibiotics would have brought the farmers to use excessive and/or less dosages, causing the advent of drug-resistant bacteria as well as economic loss and possible contamination of the local farming area. Until recently, few studies on a detailed manual for the antibiotic usage including chemotherapy procedure, dosage, and treatment schedule of the aquatic antibiotics have been conducted throughout the world. To the worse, there is no available criterion for optimal usage of aquatic antibiotics to control diseases in aquatic farms in this country because every country has its own aquacultural system. Therefore, based on the previous studies on the usage of the various antibiotics, our studies are to focus on the development of optimal method for the detection of various antibiotics on the fate of antibiotics applied to the fish, including absorption, circulation, and secretion physiology. Pharmacokinetic study were to sep up the optimal detective condition against residual antibiotics of fish by HPLC. The grinding pefloxacin for 15 min is most effective in dissolution test and pharmacokinetic parameters. Pharmacokinetic parameters were satisfactory for 15 min-grinding products and they can be explained as one-compartment model.

• Korean Journal of Optics and Photonics
• /
• v.18 no.5
• /
• pp.362-366
• /
• 2007

In this research, the optimal grinding condition has been obtained by design of experiment (DOE) fur the development of aspheric lens for the 3 Mega Pixel, 2.5x optical zoom camera-phone module. Also, the tungsten carbide (WC) mold was processed by the method of ultra precision grinding under this optimal grinding condition. The influence of diamond-liked carbon (DLC) coating on form accuracy (PV) and surface roughness (Ra) of the mold was evaluated through measurements after DCL coating using ion plating on the ground mold. Also, aspheric glass lenses were molded, some before DLC coating of the mold and some after the DLC coating. The optical characteristics of each sample, molded by the different molds, were compared with each other.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
• /
• v.20 no.9
• /
• pp.808-811
• /
• 2007

Aspheric glass lens have recently been used in camera phone module because they are more effective than spherical ones. In this paper, the grinding condition of the tungsten carbide molding core has been found after applying DOE to the development of the aspheric glass lens for the 3 Megapixel and 2.5x camera-phone module. Also, the ultra precision grinding process was investigated under this condition by experiment. Re-Ir coating was applied on the ground surface of the tungsten carbide molding core. The influence of Re-Ir coating on the form accuracy and surface roughness of molding core was compared and evaluated. The form accuracy and surface roughness of the molding core were improved by application of Re-Ir coating on the surface of the tungsten carbide molding core.

• Journal of Ocean Engineering and Technology
• /
• v.22 no.2
• /
• pp.50-57
• /
• 2008

The effect of weld improvement on the corroded fatigue life of welded structures was investigated. Toe grinding, TIG dressing and weld profiling were used as the geometric improvement methods. Fatigue tests under the corroded condition in artificial seawater were carried out to investigate the corrosion fatigue behavior of API 2W Gr.50T steel plate produced by POSCO. The test results in weld improved conditions were compared with those in as-welded condition. The test results were also compared with the design curves in UK DEn Class F. Corroded fatigue life of weld improved specimens was longer than that of as-welded specimen. Especially, the corroded fatigue life exceeded the mean SN curve in air of UK DEn Class F.

• Journal of the Korean Society for Precision Engineering
• /
• v.26 no.1
• /
• pp.51-56
• /
• 2009

Recently, with the increasing lightness and miniaturization of high resolution camera phones, the demand for aspheric glass lens has increased because plastic and spherical lens are unable to satisfy the required performance. An aspheric glass lens is fabricated by the high temperature and pressure molding using a tungsten carbide molding core, so precision grinding and coating technology for the molding core surface are required. This study investigates the effect of diamond-like carbon (DLC) and rhenium-iridium (Re-Ir) coating For aspheric molding core surface. The grinding conditions of the tungsten carbide molding core were obtained by design of experiments (DOE) for application in the ultra precision grinding process of the tungsten carbide molding core of the aspheric glass lens used in 5 megapixel, $4{\times}$ zoom camera phone modules. A tungsten carbide molding core was fabricated under this grinding condition and coated with the DLC and Re-Ir coating. By measurements, the effect of DLC and Re-Ir coating on the form accuracy and surface roughness of molding coer was evaluated.

• Journal of the Korean Society for Precision Engineering
• /
• v.7 no.4
• /
• pp.23-28
• /
• 1990

This study is to investigate the magnitude, direction and distribution of residual stresses in surface ground plate according to working conditions. The specimens were made of structural carbon steel and were machined in various grinding conditions. These were divided in two groups; heat-treated materials and non-heat-treated materials. In each working condition, let the ground specimen generate displacements using deflection-etching techniques. At the same time, these displacements were precisely measured with electronic micrometer. Through the relation formula between the plane stress and strain, which was derived using these measured data, the values of residual stress are calculated, and the results are analyzed. These results are as follows : 1. According to the working conditions in this experiment, it can be seen that the distribution of residual stress generally had same trend and the maximum residual stress remained in 20~30 ((${\mu}m$) beneath the surface. 2. It is observed that compressive residual stress changes into tensile stress in 5~20 (${\mu}m$) beneath the surface. It is suggested that such phenomenon is originated from the friction effect in grinding process. 3. As the hardness increases by the heat treatment, residual stress increases. 4. As the fatigue strength increases by the compressive residual stress, it is desirable that the dowm feed and table feed reduce. 5. It can be seen that the more great the down feed and table feed increase, the more close the changing point, where the stress changed from compressive to tensile, is colse to the surface. This is due to the resultant effects of the grinding temperature and resistence are larger than the effect of the friction.

• Journal of Technologic Dentistry
• /
• v.38 no.3
• /
• pp.157-163
• /
• 2016

Purpose: It is to compare and evaluate the change of the wear rate and phase variation of the Zirconia before and after the sintering after the grinding by a high speed equipment manufactured for the Zirconia. Methods: The specimen of the sintered Zirconia was manufactured as size of $15mm{\times}15mm{\times}2mm$. The grinding has been applied to each of all pieces of each test groups for a minute fit for each condition at same speed of 50,000 rpm by a diamond bur at high speed handpiece with injection of the air and water. For the observation of the surface before and after the sintering of the each test piece, the cross section of it was observed as 100 magnification by a scanning electron microscope after it was coated by PT, and the diffraction analysis was performed by XDR to compare the crystal phase of the Zirconia. The average surface roughness value of all specimens were evaluated. The wear test was performed at room temperature by applying a load of 1kg for 120,000 cycles for the chewing period 6 months. Wear was analyzed for the enamel cusps by measurement of the vertical substance loss with a laser scanner. Conclusion: The phase variation from the tetragonal phase to the monoclinic phase was confirmed in the test group of the pre-sintered Zirconia after the grinding, and the value of the surface roughness and the wear rate was increased in experimental group.