• Journal of Community Nutrition
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• 제7권4호
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• pp.193-200
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• 2005

This study was performed to investigate the related dietary factors associated with hypercholesterolemia in postmenopausal Korean women. The study sample comprised 455 postmenopausal women aged40 $\leq$ < 65. The hypercholesterolemic (serum cholesterol $\geq$240mg/dl group (N = 82) showed significantly higher BMI and waist circumference compared to the normal group (N = 373). However, both group did not show any significant difference in energy intake but hypercholesterolemic group demonstrated significantly lower intakes of fat and vitamin A with higher intake of vitamin C. Significant dietary factors associated with the higher risk of hypercholesterolemia included consumption frequencies of light color vegetable more than 3.79times/day (OR = 4.62 ; $95\%$ CI : 2.96 - 7.22), dried squid more than 0.08time/day (OR = 1.63 ; $95\%$ CI : 1.13 - 2.35), and beer more than 0.03time/day (OR = 1.57 ; $95\%$ CI : 1.01-2.43). Whereas consumption frequency of yellow and green leafy vegetables more than 1 time per day was associated with the significantly lower risk of hypercholesterolemia (OR = 0.06 ; 95 CI : 0.038 - 0.101). (J Community Nutrition 7(4): $193\∼200$, 2005)

• 한국재난정보학회:학술대회논문집
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• 한국재난정보학회 2022년 정기학술대회 논문집
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• pp.111-112
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• 2022

모든 도시가 발전하고 번창하기 위해서는 핵심기반시설의 재난 및 안전이 선제적으로 확보되어야 한다. 본 논문에서는 환경핵심기반시설을 중심으로 지역사회가 지속 가능한 녹색도시로 거듭나기 위해 재난준비태세 증진에 실제 활용 가능한 위험지도를 드론에 장착한 LiDAR 센서를 통해 수집한 고도 데이터를 바탕으로 제작하였다. 나아가 지진과 같은 재난 발생 시 시설에서부터 확산하는 관리 오염물의 경로 및 범위를 시범 모의하여, 기능 연속성 계획 및 재난대응 가이드와 연계를 하는 방안을 제시함으로 지자체 중심의 통합적 지역사회의 노력이 발현될 수 있도록 기초적 연구를 진행하고, 전략적 활성화 방안을 제시하였다. 본 연구는 끊임없는 성장과 거듭되는 개발로 인해 변화하는 도시의 형상에 따라 리스크를 최신화하여 대응력을 높이고, 이해관계자들에게 시각화된 재난 범위 모의를 제시함으로써 지역사회와 지자체 역량에 따른 협력적 재난대응태세에 필요한 프레임워크 도출 및 계획수립을 가능하게 한다는 점에서 큰 의의를 지닌다. 또한, 각 영역별 전문가들의 자문을 통하여 본 논문에서 제시된 확산 모의의 방법론이 타당함을 확인하였다. 무엇보다 모호한 "가능한 신속한 자원관리"와 같은 추상적인 대응계획이 아닌, 객관적인 재난자원관리계획을 수립할 수 있게 함으로써 추후 국가적 재난 및 안전역량을 계량화시킬 수 있을 것으로 사료된다.

• Journal of Nutrition and Health
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• 제18권4호
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• pp.301-311
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• 1985

Even though the anticarcinogenic effect of dietary factors especially beta - carotene has been reported by various investigators, the mechanism of the action of ${\beta}-carotene$ has not yet been identified. We carried out the present study to determine the possibilities of relative cancer risk related to dietary intake of vitamin A ( both ${\beta}-carotene$ and retinol ) and blood levels of vitamin A among Koreans. The subjects were divided into two groups; cancer patients and controls. Blood levels for ${\beta}-carotene$ and retinol were analyzed by alumina column chromatography and colorimetry. Dietary intake was examined by food profile and convenient method for evaluating nutritional status through recalling 10 years of food habits. The results obtained are as follows : 1 ) Calorie, protein, fat, and carbohydrate intakes of cancer patient were lower than those of control. Calorie and carbohydrate intakes showed no significant difference but protein and fat intakes were significantly lower in cancer patients. According to cancer sites, in stomach cancer only fat intake was significantly lower than that of control. In lung and larynx cancer calorie, protein, fat and carbohydrate intakes showed similar trend as in control. 2 ) Vitamin A intake of cancer patient was significantly lower than that of control. It was estimated that 83.6% of total Vitamin A intake were provided by ${\beta}-carotene$ for control and cancer patient respectively. 3 ) The mean intake of dietary ${\beta}-carotene$ in cancer patient was significantly lower than that in control ( $7002\;\mu}g/day$ versus $10326\;{\mu}g/day$ ) According to cancer sites in mean intake of dietary ${\beta}-carotene$ was significantly lower in all but stomach cancer compared with that of control. Lung and larynx cancer showed lowest ${\beta}-carotene$ intake with mean value of $5855{\mu}g/day$ and $5492{\mu}g/day$ respectively. 4 ) The mean intake of dietary retinol in cancer patient was significantly lower than that in control ( $245{\mu}g/day$ versus $338{\mu}g/day$ ), but the difference was not significant. 5 ) The relative risk of all cancers in the first (lowest) to the forth quartile level of ${\beta}-carotene$ consumption such as $0-5999{\mu}g/day$. $6000-8999{\mu}g/day$, $9000-11999{\mu}g/day$/ day and $12000-20000{\mu}g/day$ was 85 : 1.7 : 20 : 1.0. The relative risk of all cancers in the first (lowest) to the forth quartile level of retinol consumption, such as $0-299{\mu}g/day$, $300-599{\mu}g/day$, 600-899${\mu}g/day$, and $900-1200{\mu}g/day$, was 1.14 : 067 : 0.21 : 1.0. 6 ) The various food group consumption of cancer patient were significantly lower than those of control in green leafy vegetables, fruits, sea weeds, milk and cheese and eggs. But the Kimchie consumption in cancer patient was three fold higher than that of control ( $1840\;{\mu}g/day$ versus $562\;{\mu}g/day$ ) and in the stomach cancer, Kimchie consumption was the highest, ( $1890\;{\mu}g/day$) According to cancer sites, the consumption of green leafy vegetables was significantly lower in all but stomach cancer compared to control and other vegetables showed no difference between two. In lung and larynx cancer, green leafy vegetables consumption was lowest ( $6094{\mu}g/day$ $5921{\mu}g/day$) and milk and cheese consumption was also( $5\;{\mu}g/day$ and $11{\mu}g/day$) 7 ) The recovery of ${\beta}-carotene$ from human serum by alumina column chromatography was $94.4{\pm}2.3%$. 8 ) Cancer patients showed significantly lower serum retinol ($56.4{\pm}18.1\:{\mu}g/100ml$ versus $72.2{\pm}21.8\:{\mu}g/100ml$) and ${\beta}-carotene$ ($48.9{\pm}33.8\:{\mu}g/100ml$ versus $72.2{\pm}42.6\:{\mu}g/100ml$) concentrations than in controls. 9 ) But breast cancer patients were not significantly different from controls in their serum retinol and ${\beta}-carotene$ concentrations.

• 국제지역연구
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• 제21권2호
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• pp.45-70
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• 2017

관광산업은 기후변화에 민감한 부분이 많고 저탄소녹색성장의 관점에서 새로운 기회와 위협을 제공할 수 있다는 측면에서 연구의 가치가 있다. 기후변화로 인한 소비자들의 인식 및 태도의 변화가 관광수요와 관광선택에 어떠한 영향을 미치는지에 대한 연구는 매우 중요하며, 현재도 그 영향이 진행되고 있는 상황이다. 본 연구에서는 기후변화 인식과 태도가 관광 경험, 가치, 위험요인, 만족도, 행동의도에 미치는 영향관계를 규명하여 관광활동의 주체인 관광객의 기후변화에 따른 심리적 특성에 대한 검토를 통해 관광객들의 다양한 욕구 및 변화를 파악하였다. 이를 통해 마케팅 전략을 수립하는데 필요한 시사점을 제공할 수 있었다. 본 연구의 결과는 다음과 같다. 첫째, 기후변화 인식은 관광경험, 관광가치에 유의한 영향을 미치는 반면 관광위험요인은 영향을 미치지 않는 것으로 나타났고, 둘째, 중국 관광객이 한국 관광객보다 전반적인 영향력이 더 크게 나타났다. 셋째, 기후변화 태도는 관광경험과 관광위험요인에는 유의한 영향을 미치는 반면 관광가치에는 영향을 미치지 않는 것으로 나타났고, 넷째, 관광경험, 관광가치는 관광만족도에 유의한 영향을 미치는 반면 관광위험요인은 관광만족도에 영향을 미치지 않는 것으로 나타났으며, 다섯째, 관광경험, 관광가치, 관광위험요인은 행동의도에 모두 영향을 미치지 않는 것으로 나타났다.

• Journal of Veterinary Science
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• 제22권5호
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• pp.73.1-73.11
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• 2021

Background: Feline calicivirus (FCV) is a common pathogen of felids, and FCV vaccination is regularly practiced. The genetic variability and antigenic diversity of FCV hinder the effective control and prevention of infection by vaccination. Improved knowledge of the epidemiological characteristics of FCV should assist in the development of more effective vaccines. Objectives: This study aims to determine the prevalence of FCV in a population of cats with FCV-suspected clinical signs in Hangzhou and to demonstrate the antigenic and genetic relationships between vaccine status and representative isolated FCV strains. Methods: Cats (n = 516) from Hangzhou were investigated between 2018 and 2020. The association between risk factors and FCV infection was assessed. Phylogenetic analyses based on a capsid coding sequence were performed to identify the genetic relationships between strains. In vitro virus neutralization tests were used to assess antibody levels against isolated FCV strains in client-owned cats. Results: The FCV-positive rate of the examined cats was 43.0%. Risk factors significantly associated with FCV infection were vaccination status and oral symptoms. Phylogenetic analysis revealed a radial phylogeny with no evidence of temporal or countrywide clusters. There was a significant difference in the distribution of serum antibody titers between vaccinated and unvaccinated cats. Conclusions: This study revealed a high prevalence and genetic diversity of FCV in Hangzhou. The results indicate that the efficacy of FCV vaccination is unsatisfactory. More comprehensive and refined vaccination protocols are an urgent and unmet need.

• Journal of Genetic Medicine
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• 제18권1호
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• pp.38-43
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• 2021

Purpose: Demand for genetic counseling on cancer predisposition syndrome is increasing. We evaluated the psychological effect on counselees after genetic counseling at a clinic in a single center. Materials and Methods: We surveyed a total of 72 enrolled participants who visited a genetic counseling clinic at the Samsung Medical Center (SMC). The initial survey was conducted before the first genetic counseling session, and the second survey was conducted after the second genetic counseling session. A total of 43 participants completed both the initial and second surveys. Results: The initial survey of 72 participants indicated higher feelings of guilt in the group with religion, higher depression and anxiety in the group with a diagnosis of self, and higher anxiety in the group on self-referral to the genetic counseling clinic. In the completed survey of 43 participants, overall decreased depression was observed after the second genetic counseling session (P=0.013). Risk perception and anxiety decreased in the group diagnosed with benign variant/variant of uncertain significance (BV/VUS, 25/3) and increased in the group diagnosed with pathogenic variant (PV, 15). Risk perception and anxiety differed between the BV/VUS and PV groups (P<0.001 and P=0.03, respectively). Conclusion: The genetic counseling clinic at the SMC was effective in ameliorating the depression score. Assessment of survey results revealed different depression scores, feelings of guilt and anxiety, and different effects of the genetic counseling clinic, depending on the subgroups. Understanding the needs and psychological characteristics of different groups is necessary for improving genetic counseling services.

• 디지털융복합연구
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• 제14권11호
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• pp.241-247
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• 2016

국내 교통제어신호는 주기적인 간격으로 녹색신호로 바뀌는 시스템과 차량의 수가 많지 않은 심야 또는 통행량이 적은 지방도로에서 황색, 적색 점멸신호를 사용하고 있다. 그러나 차량의 수가 많지 않은 심야의 한적한 도로에서 주기적인 신호체계를 사용할 경우 지체 및 정체를 발생하게 된다. 또한 점멸신호를 사용할 경우 충돌사고의 위험성이 크다. 본 논문은 센서 데이터를 포함한 비콘메세지를 분석한 후 신호체계를 재배치하는 반응형 녹색점멸 신호시스템을 제안한다. 제안 시스템은 심야에 간선 도로 및 하위 도로에서 신호가 녹색점멸을 유지하고 있다가 차량이 무선 커버리지 RSE내에 진입하면 비콘메세지를 주기적으로 전송하고 Agent System이 메세지를 분석해 신호를 변경한다. 차량은 변경한 신호 시스템을 따라 차량이 이동하는 시스템이며, 이는 통행량이 적은 도로에서 원활한 흐름과 차량 간 충돌 사고를 예방할 수 있다. 시뮬레이션 결과 성능 면에서 교통 처리량과 평균 대기시간이 기존 신호 시스템보다 10~30%향상되었다.

• 대한약침학회지
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• 제7권1호
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• pp.87-100
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• 2004

Objective : This research was performed to investigate the effect of herbal acupuncture(Atratylodes japonica, Coix lachrymajobi, Ephedra sinica, Atratylodes japonica mixed with Coix lachrymajobi and Ephedra sinica mixed with Green tea) at Pungnyung(ST40) and Umnungchon(SP9) on weight gain, food intake, food efficiency, serum of lipid concentrations, liver function and HDL to total cholesterol ratio of rats fed high fat diet for 5weeks. Method : Experimental groups were divided into normal group(Normal), high fat diet group(Control), high fat diet and Atractylodes japonica-herbal acupuncture group(AJ), high fat diet and Coix lachrymajobi-herbal acupuncture group(CL), high fat diet and Ephedra sinica-herbaI acupuncture group(ES), high fat diet and Atractylodes japonica+Coix lachrymajobi-herbal acupuncture group(AJ+CL), Ephedra sinica+Green tea-herbal acupuncture group(ES+GT). Herbal acupuncture was bilaterally treated at the level of 132.5mg/kg body weight per 2day. Results : Body weight and food efficiency were decreased in AJ, ES, AJ+CL, ES+GT. The level of serum total cholesterol, triglyceride and free fatty acid were increased in AJ, ES, ES+GT. That of serum HDL-cholesterol was increased in AJ. The change of food intake, the level of serum phospholipid and ALP were not significant. The HDL to Total cholesterol ratio was increased in AJ and ES. Conclusion : Atractylodes japonica-herbal acupuncture in ST40 SP9 is effective on Body weight, food efficiency ratio, the level of serum lipid, protection of liver function and prevention cardiovascular risk by obesity induced by high fat diet. Herbal acupuncture mixed Ephedra sinica with Green tea can control the body weight, food efficiency ratio and the level of serum lipid.

• Journal of Microbiology and Biotechnology
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• 제21권4호
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• pp.387-390
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• 2011

Nude mice (BALB/c) were grafted with human 293 cells and PERV (porcine endogenous retrovirus)-IRES-EGFP (a packageable retroviral vector plasmid containing an internal ribosome entry site-enhanced green fluorescent protein)-producing pig PK15 cells in order to determine whether the pig cells could transmit PERV-IRES-EGFP to mice and human 293 cells in vivo. None of the transplanted human 293 cell lines were infected by PERV, but PCR analysis identified PERV-B provirus integration into both the heart and salivary gland of the inoculated nude mice. Our data indicate that hearts and salivary glands can be used to identify PERV-B receptors.

• 대한후두음성언어의학회지
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• 제9권2호
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• pp.147-151
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• 1998

Primary localized laryngeal amyloidosis is an uncommon disorder of unknown cause that occurs in the absence of systemic amyloidosis or associated disease. There is a risk of either missing concomitant systemic amyloidosis or exhaustively investigating for this when it is not present through failure to appreciate the nature of the disease. We present 2 cases of primary localized laryngeal amyloidosis in supraglottic region. Biopsy of the mass of patients revealed findings consistent with amyloidosis, which were Congo red reaction with a apple green birefringence in polarized light fluorescence microscopy. An extensive workup for systemic amyloidosis was negative. All of two cases were treated by vaporization via $CO_2$ LASER using "Swiftlase Flshscan" for creating a wide, shallow char-free treatment site by precisely controlling ablation depth without causing residual thermal damage to tissue. The postoperative recovery of all cases was uneventful with good vocal quality and no aspiration. At the present time, the patients have no evidence of disease, recurrence and complication.