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Comparison between Instrumented Mini-TLIF and Instrumented Circumferential Fusion in Adult Low-Grade Lytic Spondylolisthesis : Can Mini-TLIF with PPF Replace Circumferential Fusion?

  • Kim, Jin-Sung;Kim, Dong-Hyun;Lee, Sang-Ho
    • Journal of Korean Neurosurgical Society
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    • v.45 no.2
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    • pp.74-80
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    • 2009
  • Objective : To evaluate clinical and radiological results of two different fusion techniques in adult low-grade isthmic spondylolisthesis. Methods : Between November 2003 and December 2004, 46 consecutive patients underwent instrumented mini-transforaminal lumbar interbody fusion (mini-TLIF) (group I) at Wooridul Spine Hospital, Seoul, Korea. Between February 2003 and October 2006, 32 consecutive patients underwent instrumented circumferential fusion (group II) at Leon Wiltse Memorial Hospital, Suwon, Korea. The mean follow-up periods were 29.7 and 26.1 months, respectively. Results : Mean visual analog scale (VAS) scores for back and leg pain decreased, respectively, from 6.98 and 6.33 to 2.3 and 2.2 in group I and from 7.38 and 6.00 to 1.7 and 1.0 in group II. Mean Oswestry disability index (ODI) improved from 51.85% to 14.4% in group I and from 60% to 9.1% in group II. In both groups, VAS and ODI scores significantly changed from pre- to postoperatively (p<0.001), but postoperative outcome between groups was statistically not significant. Radiologic evidence of fusion was noted in 95.7% and 100% of the patients in group I and II, respectively. In both groups, changes in disc height, segmental lordosis, degree of listhesis, and whole lumbar lordosis between the pre- and postoperative periods were significant except whole lumbar lordosis in both groups. Conclusion : Clinical and functional outcomes demonstrate no significant differences between groups in treating back and leg pain of adult patients with low-grade isthmic spondylolisthesis. However, in terms of operative data (i.e. operation time and hospital stay), instrumented mini-TLIF demonstrated better results.

Comparison of Single-Incision, Single-Bundle Posterior Cruciate Ligament Reconstruction Using Allograft Tendon (동종건을 이용한 단일 절개, 단일 다발 후방십자인대 재건술의 비교)

  • Kyung, Hee-Soo;Cheon, Sang-Ho;Park, Kyung-Hyun;Jung, Jae-Wook
    • Journal of the Korean Arthroscopy Society
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    • v.16 no.2
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    • pp.107-113
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    • 2012
  • Purpose: The purpose of this study was to evaluate the posterior cruciate ligament (PCL) reconstruction with single bundle, single-incision technique using Achilles tendon and tibialis anterior allograft with ligament remnant preservation. Materials and Methods: Twenty six patients underwent PCL reconstruction was included. There were 21 males and 5 females. Mean age was 32 years. Used graft was a fresh frozen Achilles tendon allograft (group I, 14 cases) and tibialis anterior allograft (group II, 12 cases). Arthroscopic PCL reconstruction was performed using transtibial, single-incision and single bundle technique with remnant preserving as possible. For clinical evaluation, range of motion, posterior drawer test, Lysholm score, Tegner activity scale, International Knee Documentation Committee (IKDC) grade and posterior stress radiograph were used. The mean follow-up period was 21.6 months (12-40 months). Associated injuries were 5 medial collateral ligament injuries, which were treated by conservative method. Results: Range of motion (ROM) was returned to normal range in 24 cases, but ROM deficit under $10^{\circ}$ flexion was 2 cases at final follow-up period. Preoperative posterior drawer test was 17 cases in grade II and 9 cases in grade III. At final follow-up 13 cases returned within normal grade, 7 cases grade I and 6 cases grade II posterior instability. Lysholm mean score was improved from preoperatively 62 to 90 at final follow-up period. Tegner activity mean scale improved from preoperatively 3.5 to 5.6 at final follow-up period. IDKC grade was grade A was 3 cases, grade B 17 cases, grade C 6 cases. In posterior stress radiograph, posterior displacement was improved from mean 12 mm preoperative to 4.5 mm at final follow-up. There were no statistical differences between two groups in clinical evaluations. There were two cases of re-rupture of graft at the bone-tendon junction in group I. Conclusion: We had successful results of PCL reconstruction with single-incision, single bundle technique using Achilles and tibialis anterior allograft without difference between two groups in patients with PCL injury. There were more re-rupture of graft in Achilles tendon group.

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Henoch-$Sch{\ddot{o}}nlein$ Nephritis in Children (소아 Henoch-$Sch{\ddot{o}}nlein$ 신염의 추적 관찰)

  • Jang, Hee-Suk;Hong, In-Hee;Go, Cheol-Woo;Koo, Ja-Hun;Kwak, Jung-Sik
    • Childhood Kidney Diseases
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    • v.4 no.2
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    • pp.120-126
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    • 2000
  • Purpose : This retrospective study has been undertaken to find out the clinical outcome of children with HS nephntis and its relationship with initial clinical presentation and/or renal pathologic finding. Patients and methods : Study population consisted of 59 children with HS nephritis who have been admitted to the Pediatric department of Kyungpook University Hospital from 1987 to 1999, and biopsy was done with indications of heavy proteinuria (> 1 g/m2/day) lasting over 1 month, nephrotic syndrome, and persistent hematuria and/or proteinuria over 1 year. Patients were divided clinically into 3 groups ; isolated hematuria, hematuria with proteinuria and heavy proteinuria (including nephrotic syndrome). Biopsy findings ore graded from I-V according to International Study of Kidney Disease in Children (ISKDC). Results : Mean age of presentation was $8.1{\pm}3.0$ years and slight male preponderance m noted (33 boys md 26 girls). Histopathologic grading showed Grade I ; 2, Grade II ; 44, and Grade III ; 13 cases. Clinical outcome at the follow-up period of 1-2 year (49 cases) and 3-4 years (30 cases) shooed normal urinalysis in 75 (30.6$\%$) and 18 cases (60.0$\%$), persistent isolated hematuria in 20 (40.8$\%$) and 2 cases (6.7$\%$), hematuria with proteinuria in 11 (22.5$\%$) and 8 cases (26.6$\%$), and persistent heavy proteinuria in 3 (6.1$\%$) and 2 cases (6.7$\%$) respectively. Clinical outcome according to histopathologic grading showed the frequency of normalization of urinalysis being lower in Grade III compared to grade I or II. Clinical outcome according to initial clinical presentation showed no relationship to the normalization or urinalysis at follow-up periods. However, 15-20$\%$ of children with initial heavy proteinuria showed persistent heavy proteinuria (3 out of 20 cases at 1-2 years, and 2 out of 10 case at 3-4 years of follow-up periods). Conclusion : The majority of children with HS nephritis (histopathologic grade I, II, III) improved within 3-4 years and persistent heavy proteinuria was seen only in a kw of children with initial clinical presentation of heavy proteinuria.

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Somatotype Characteristics of Elementary School Girls (Part I) -Focusing somatotype changing charcteristics on each grade group- (학령기 여아의 체형 특성(제1보) -학령기별 체형 변이 특성을 중심으로-)

  • 장정아;권영숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.23 no.7
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    • pp.941-952
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    • 1999
  • The purposes of this study were to provide the fundamental data on elementary school girls' somatotype for their clothing construction by contemplating the stage of physical growth dividing into the period of school age and characterizing the variation of body type according to the school age. The results are as follows : 1. Form the results of one-way variables analysis and multiple comparson test(Duncan's test) classification of the period school age can be divided into 'early grade(1 2 grade)' ' middle grade(3 4 grade)' and 'later grade(5 6 grade)' 2. As the results of analyzing Mean Coefficient of Variation and Standard Deviation graph for direct and indirect measurments and index especially of the Coefficient Variation that explain individual difference of growth the items of height indicates individual difference related with height of lower body of early grade group the items of length individual difference related with length of upper body of later grade group and the items of circumference make little difference. The items of anagle makes pretty higher value that direct measurements and especially in lower angle of chest make a distinctive difference, This fact proves that children's somatotype change from the belly part extruded forwards of early and middle grade to the upper body part slanted slightly forward of later grade.

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Significance of Early Esophagoscopy in Corrosive Esophagitis (부식성 식도염에서의 조기 식도경술의 의의)

  • 임병석;봉정표;박순일;문태용;윤강묵
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1983.05a
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    • pp.12.2-13
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    • 1983
  • Corrosive injuries of the esophagus by accident or suicidal attempt, though decreasing in number, still represent an important problem of our national pathology. One of the most difficult problems facing any physician is the diagnosis and management of caustic ingestion. In order to determine the extent of esophageal bums, to prevent the potential complication, to increase the therapeutic effect, the use of esophagoscopy is an essential step, and it has lessened an unnecessary admission and treatment. The authors have found the value of early esophagoscopy in selected 41 corrosive esophagitis patient who were admitted to Dept. of ENT, Wonju medical college, Yonsei university between 1980. 1-1982. 12

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Satisfaction about Internet Shopping Mall and Purchasing Intention of Fashion Goods - Difference of Department of Fashion Design and Non Fashion Design - (인터넷쇼핑몰에 대(對)한 만족도(滿足度)와 의류제품구매의도(衣類製品購買意圖)의 차이(差異) - 의상전공(衣裳專攻)과 비전공(非專攻) 대학생(大學生)의 비교(比較) -)

  • Park, Hea-Ryung;Kim, Si-Wuel
    • Journal of Fashion Business
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    • v.5 no.3
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    • pp.19-34
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    • 2001
  • The purpose of this study was to investigate the differences of the general characteristics of subjects, the utilizing realities and the degree of satisfaction in the shopping mall and purchasing intention between group I that specializes in fashion design and group II that doesn't specialize in it. The results are summarized as the following six aspects. First, as a result of the general characteristics of subjects and the utilizing realities, the most different variables were the visiting frequency and the goods purchasing frequency. The result indicated that group II took more interests than group I. Second, as a result of the degree of satisfaction according to the factors of the general characteristics of subjects and the utilizing realities in the shopping mall, both group I and group II showed high degree of satisfaction in factor 1 (variety of event) whereas both groups showed relatively low degree of satisfaction in factor 3 (variety of goods). Third, as a result of the degree of satisfaction according to the general characteristics of subjects and the utilizing realities, group I showed significant differences in the degree of satisfaction according to a monthly allowance of pocket money and goods purchasing frequency and group II showed significant differences in the degree of satisfaction according to grade, the utilizing reason, goods purchasing frequency. Fourth, as a result of purchasing intention of fashion goods according to the general characteristics of subjects and the utilizing realities, group I showed the higher purchasing intention of fashion goods in group that the terms of payment was on-line payment than group that they was credit card. On the other hand, group II showed a significant difference in grade, which showed that group that was above third grade had the higher purchasing intention of fashion goods than group that was under third grade. Fifth, as a result of purchasing intention of fashion goods according to the degree of satisfaction, group I showed significant differences in factor 1 and factor 3 among the degree of satisfaction. In other words, group that had high degree of satisfaction in factor 1 showed the higher purchasing intention of fashion goods than other groups and group that had medium degree of satisfaction in factor 3 showed the higher purchasing intention of fashion goods than other groups. In group II, on the other hands, group that had high total degree of satisfaction showed the higher purchasing intention of fashion goods than other groups. Sixth, as a result of relative influencing power of independent variable with respect to purchasing intention of fashion goods in group I, the higher degree of satisfaction in factor 1 and the lower degree of satisfaction in factor 3 showed, the higher purchasing intention of fashion goods showed. As a result of relative influencing power of independent variable in group II, however, the higher grade and the higher degree of satisfaction in factor 1 showed, the higher purchasing intention of fashion goods showed.

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Association of tumor differentiation grade and survival of women with squamous cell carcinoma of the uterine cervix

  • Matsuo, Koji;Mandelbaum, Rachel S.;Machida, Hiroko;Purushotham, Sanjay;Grubbs, Brendan H.;Roman, Lynda D.;Wright, Jason D.
    • Journal of Gynecologic Oncology
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    • v.29 no.6
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    • pp.91.1-91.12
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    • 2018
  • Objective: To examine the association between tumor grade and survival for women with squamous cervical cancer. Methods: This retrospective observational study utilized the Surveillance, Epidemiology, and End Result program data between 1983 and 2013 to examine women with squamous cervical cancer with known tumor differentiation grade. Multivariable analyses were performed to assess independent associations between tumor differentiation grade and survival. Results: A total of 31,536 women were identified including 15,175 (48.1%) with grade 3 tumors, 14,084 (44.7%) with grade 2 neoplasms and 2,277 (7.2%) with grade 1 tumors. Higher tumor grade was significantly associated with older age, higher stage disease, larger tumor size, and lymph node metastasis (all, p<0.001). In a multivariable analysis, grade 2 tumors (adjusted-hazard ratio [HR]=1.21; p<0.001) and grade 3 tumors (adjusted-HR=1.45; p<0.001) were independently associated with decreased cause-specific survival (CSS) compared to grade 1 tumors. Among the 7,429 women with stage II-III disease who received radiotherapy without surgical treatment, grade 3 tumors were independently associated with decreased CSS compared to grade 2 tumors (adjusted-HR=1.16; p<0.001). Among 4,045 women with node-negative stage I disease and tumor size ${\leq}4cm$ who underwent surgical treatment without radiotherapy, grade 2 tumors (adjusted-HR=2.54; p=0.028) and grade 3 tumors (adjusted-HR=4.48; p<0.001) were independently associated with decreased CSS compared to grade 1 tumors. Conclusion: Our study suggests that tumor differentiation grade may be a prognostic factor in women with squamous cervical cancer, particularly in early-stage disease. Higher tumor grade was associated with poorer survival.

Selection of the Priority Order for Additional Green Spaces for Urban Park and Green Network (공원녹지 네트워크 구축을 위한 추가녹지 조성 우선순위 선정)

  • SaGong, Jung-Hee;Ra, Jung-Hwa;Cho, Hyun-Ju
    • Journal of the Korean Institute of Landscape Architecture
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    • v.34 no.6 s.119
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    • pp.10-21
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    • 2007
  • The purpose of this paper was to classify areas demanding to be transformed to green spaces and evaluate their grades for urban park and green networks. The results of this study are summarized below; 1. The results of the classified green spaces in the research areas fall into three types including children parks, neighborhood parks, and public green spaces. The three types of green spaces were analysed with recreational indexes. The zones disturbing the green-networks were sorted out. These zones should be changed into a supplementary green spaces for improving the recreational functions in the city. 2. For urban park and green networks, distances between the parks and size of the parks were adopted as indices. Based on the index of distances between the parks, disturbing zones were evaluated with 3 grades. The first grade includes primary industrial complexes and housing complexes. The second grade was observed mostly in industrial complex areas. The third grade includes housing complexes. Based on the indexes of size of parks, disturbing zones were evaluated with 2 grades. In the case of grade I, it appeared in housing complex. In the case of grade II, it appeared in industrial complex. 3. Then, we prioritized the disturbing zones with severity in order to make supplementary green spaces. Through the process, the zones of the grade I for two each recreational index were evaluated to two grades. The analysis results of evaluated zones were that grade II appeared over industrial and housing complexes widely. Grade I appeared over housing complexes. 4. It is necessary that the grade of disturbing zones should be considered as an order to make green spaces to supplement a green-network. For this, we formed a basic frame of a green-networks in Dalsu-Gu and placed the disturbing zones on the basic frame of a green-network. Consequently, The results were that the green-networks in Dalsu-Gu was composed on four green-network axes and its shape mirrored a cruciform (+) of northwest$\leftrightarrow$southeast direction and southwest$\leftrightarrow$northeast direction.

Inhibition of glutathion-S-transferase and amidase by impurities in technical grade benfuracarb (Benfuracarb 원제에 함유된 불순물들의 glutathione-S-transferase와 amidase 저해 특성)

  • Yum, Chang-Sub;Kim, Song-Mun;Yu, Ji-Sook;Hur, Jang-Hyun
    • The Korean Journal of Pesticide Science
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    • v.6 no.1
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    • pp.31-35
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    • 2002
  • Objectives of this study were to determine if impurities in technical grade benfuracarb inhibit glutathione-S-transferase and amidase and to identify structures of impurities in technical grade benfuracarb. Technical grade benfuracarb, active ingredient, and impurity inhibited glutathione-S-transferase, and their $I_{50}$ were $9.7{\times}10^{-4}M,\;>1.0{\times}10^{-3}M,\;1.8{\times}10^{-4}M$, respectively. Such inhibition, however, was not higher than that by ethacrynic acid, a selective inhibitor to GST. Technical grade benfuracarb, active ingredient, and impurity also inhibited amidase, and their $I_{50}$ were $6.0{\times}10^{-5}M,\;4.3{\times}10^{-4}M,\;7.6{\times}10^{-5}M$, respectively. Our results show that the inhibition of both detoxifying enzymes by impurities in benfuracarb was 10-fold lower than that by active ingredient, suggesting that both active ingredient and impurities are involved in the inhibition of both detoxifying enzymes. Of four impurities (IM $1{\sim}4$) that were separated from technical grade benfuracarb, IM 2 and IM 3 inhibited GST and amidase. Based on data from IR, $^1H$-NMR, $^{13}C$-NMR and MS, it was determined that IM 2 is ethyl-N-isopropylamino propionate and IM 3 is ethyl-N-isopropyl-N(chlorosulfenyl)aminopropionate.

Transfer Learning Using Convolutional Neural Network Architectures for Glioma Classification from MRI Images

  • Kulkarni, Sunita M.;Sundari, G.
    • International Journal of Computer Science & Network Security
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    • v.21 no.2
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    • pp.198-204
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    • 2021
  • Glioma is one of the common types of brain tumors starting in the brain's glial cell. These tumors are classified into low-grade or high-grade tumors. Physicians analyze the stages of brain tumors and suggest treatment to the patient. The status of the tumor has an importance in the treatment. Nowadays, computerized systems are used to analyze and classify brain tumors. The accurate grading of the tumor makes sense in the treatment of brain tumors. This paper aims to develop a classification of low-grade glioma and high-grade glioma using a deep learning algorithm. This system utilizes four transfer learning algorithms, i.e., AlexNet, GoogLeNet, ResNet18, and ResNet50, for classification purposes. Among these algorithms, ResNet18 shows the highest classification accuracy of 97.19%.