• Title/Summary/Keyword: Grade 91

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Association of tumor differentiation grade and survival of women with squamous cell carcinoma of the uterine cervix

  • Matsuo, Koji;Mandelbaum, Rachel S.;Machida, Hiroko;Purushotham, Sanjay;Grubbs, Brendan H.;Roman, Lynda D.;Wright, Jason D.
    • Journal of Gynecologic Oncology
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    • v.29 no.6
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    • pp.91.1-91.12
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    • 2018
  • Objective: To examine the association between tumor grade and survival for women with squamous cervical cancer. Methods: This retrospective observational study utilized the Surveillance, Epidemiology, and End Result program data between 1983 and 2013 to examine women with squamous cervical cancer with known tumor differentiation grade. Multivariable analyses were performed to assess independent associations between tumor differentiation grade and survival. Results: A total of 31,536 women were identified including 15,175 (48.1%) with grade 3 tumors, 14,084 (44.7%) with grade 2 neoplasms and 2,277 (7.2%) with grade 1 tumors. Higher tumor grade was significantly associated with older age, higher stage disease, larger tumor size, and lymph node metastasis (all, p<0.001). In a multivariable analysis, grade 2 tumors (adjusted-hazard ratio [HR]=1.21; p<0.001) and grade 3 tumors (adjusted-HR=1.45; p<0.001) were independently associated with decreased cause-specific survival (CSS) compared to grade 1 tumors. Among the 7,429 women with stage II-III disease who received radiotherapy without surgical treatment, grade 3 tumors were independently associated with decreased CSS compared to grade 2 tumors (adjusted-HR=1.16; p<0.001). Among 4,045 women with node-negative stage I disease and tumor size ${\leq}4cm$ who underwent surgical treatment without radiotherapy, grade 2 tumors (adjusted-HR=2.54; p=0.028) and grade 3 tumors (adjusted-HR=4.48; p<0.001) were independently associated with decreased CSS compared to grade 1 tumors. Conclusion: Our study suggests that tumor differentiation grade may be a prognostic factor in women with squamous cervical cancer, particularly in early-stage disease. Higher tumor grade was associated with poorer survival.

Comparison of Crack Growth Test Results at Elevated Temperature and Design Code Material Properties for Grade 91 Steel (Grade 91 강의 고온 균열진전 실험 결과와 설계 물성치의 비교)

  • Lee, Hyeong-Yeon;Kim, Woo-Gon;Kim, Nak-Hyun
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.39 no.1
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    • pp.27-35
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    • 2015
  • The material properties of crack growth models at an elevated temperature were derived from the results of numerous crack growth tests for Mod.9Cr-1Mo (ASME Grade 91) steel specimens under fatigue loading and creep loading at an elevated temperature. These crack growth models were needed for defect assessment under creep-fatigue loading. The mathematical crack growth rate models for fatigue crack growth (FCG) and creep crack growth (CCG) were determined based on the test results, and the models were compared with those of the French design code RCC-MRx to investigate the conservatism of the code. The French design code RCC-MRx provides an FCG model and a CCG model for Grade 91 steel in Section III Tome 6. It was shown that the FCG model of RCC-MRx is conservative, while the CCG model is non-conservative compared with the present test data. Thus, it was shown that further validation of the property was required. Mechanical strength tests and creep tests were also conducted, and the test results were compared with those of RCC-MRx.

Long-term Creep Life Prediction Methods of Grade 91 Steel (Grade 91 강의 장시간 크리프 수명 예측 방법)

  • Park, Jay-Young;Kim, Woo-Gon;EKAPUTRA, I.M.W.;Kim, Seon-Jin;Jang, Jin-Sung
    • Journal of Power System Engineering
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    • v.19 no.5
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    • pp.45-51
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    • 2015
  • Grade 91 steel is used for the major structural components of Generation-IV reactor systems such as a very high temperature reactor (VHTR) and sodium-cooled fast reactor (SFR). Since these structures are designed for up to 60 years at elevated temperatures, the prediction of long-term creep life is very important to determine an allowable design stress of elevated temperature structural component. In this study, a large body of creep rupture data was collected through world-wide literature surveys, and using these data, the long-term creep life was predicted in terms of three methods: Larson-Miller (L-M), Manson-Haferd (M-H) and Wilshire methods. The results for each method was compared using the standard deviation of error. The L-M method was overestimated in the longer time of a low stress. The Wilshire method was superior agreement in the long-term life prediction to the L-M and M-H methods.

Treatment Option for High Grade Spleen Injury and Predictive Factors for Non-operative Management

  • Na, Joung Won;Lee, Jung Nam;Yu, Byung Chul;Lee, Min A;Park, Jae Jung;Lee, Gil Jae
    • Journal of Trauma and Injury
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    • v.30 no.3
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    • pp.91-97
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    • 2017
  • Purpose: Purpose: The prognostic factors of non-operative management (NOM) in high-grade spleen injuries have been extensively studied, but factors that would help treatment decisions are lacking. We compared the characteristics of the patients to identify the factors affecting treatment choices. Methods: This is a review of 207 blunt spleen injury patients from January 2004 to December 2013. We compared clinical features and mortality between surgery and NOM, and used multivariate regression analysis to find the factor most strongly associated with prognosis. Results: Of the 207 patients, 107 had high-grade spleen injury patents (grade III or above). Of these, 42 patients underwent surgery and 65 patients underwent NOM. The mortality was 7% following surgery, 3% with NOM. The amount of packed red blood cells transfused in the first 24 hours and spleen injury grade were associated with management type, and mortality was highly associated with activated partial thromboplastin time (aPTT) and spleen injury grade. Conclusions: The grade of spleen injury was associated with management and mortality, so correctly assessing the spleen injury grade is important.

Correlation Between Transient Regime and Steady-State Regime on Creep Crack Growth Behavior of Grade 91 Steel (Grade 91 강의 크리프 균열성장 거동에 대한 천이영역과 정상상태영역의 상관 관계)

  • Park, Jae-Young;Kim, Woo-Gon;Ekaputra, I.M.W.;Kim, Seon-Jin;Kim, Eung-Seon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.39 no.12
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    • pp.1257-1263
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    • 2015
  • A correlation between the transient regime and steady state regime on the creep crack growth (CCG) for Grade 91 steel, which is used as the structural material for the Gen-IV reactor systems, was investigated. A series of CCG tests were performed using 1/2" CT specimens under a constant applied load and at a constant temperature of $600^{\circ}C$. The CCG rates for the transient and steady state regimes were obtained in terms of $C^*$ parameter. The transient CCG rate had a close correlation with the steady-state CCG rate, as the slope of the transient CCG data was very similar to that of the steady state data. The transient rate was slower by 5.6 times as compared to the steady state rate. It can be inferred that the steady state CCG rate, which is required for long-time tests, can be predicted from the transient CCG rate obtained from short-time tests.

A Comparative Study of College Adjustment and Life Stress of Nursing Students by Grades (간호대학생의 학년에 따른 대학적응과 생활 스트레스 비교연구)

  • Jung, So Young
    • Journal of Industrial Convergence
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    • v.17 no.4
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    • pp.139-146
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    • 2019
  • This study was done to compare college adjustment and life stress of nursing students by grades in Korea. A total of 417 participants were recruited using a convenient sampling method. Data were collected using a self-reported questionnaire from October 15 to October 30, 2019. The results of the study showed that the college adjustment of nursing students was significantly higher in 4th grade (3.45 ± 0.53) than 1st grade (3.18 ± 0.61). Life stress was highest in first grade (0.91 ± 0.46), followed by fourth grade, second grade, and third grade. college adaptation and life stress by grade were inversely correlated in all grades. Therefore, it is necessary to check the difference between college adaptation and life stress according to grade level, and to prepare customized programs according to the grades, so that students can make a good college adjustment through stress management of nursing college students.

Microstructural Evolution of Grade 91 Steel upon Heating at 760~1000℃

  • He, Yinsheng;Chang, Jungchel;Lee, Je-Hyun;Shin, Keesam
    • Korean Journal of Materials Research
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    • v.25 no.11
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    • pp.607-611
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    • 2015
  • The microstructural evolution of Grade 91 tempered martensite ferritic steels heat treated at $760{\sim}1000^{\circ}C$ for two hours was investigated using scanning electron microscopy(SEM), energy disperse spectroscopy(EDS), electron backscattered diffraction (EBSD), and transmission electron microscopy(TEM); a microhardness tester was also employed, with a focus on the grain and precipitate evolution process as well as on the main hardening element. It was found that an evolution of tempered martensite to ferrite($760{\sim}850^{\circ}C$), and to fresh martensite($900{\sim}1000^{\circ}C$), occurred with the increase of temperature. Simultaneously, the parabolic evolution characteristics of the low angle grain boundary(LAGB) increased with the increase of the heating temperature(highest fraction of LAGB at $925^{\circ}C$), indicating grain recovery upon intercritical heating. The main precipitate, $M_{23}C_6$, was found to be coarsened slightly at $760{\sim}850^{\circ}C$; it then dissolved at $850{\sim}1000^{\circ}C$. Besides this, $M_3C$ cementite was formed at $900{\sim}1000^{\circ}C$. Finally, the experimental results show that the hardness of the steel depended largely on the matrix structure, rather than on the precipitates, with the fresh martensite showing the highest hardness value.

The education evaluation of basic CPR on middle school students (중학교 재학생의 기본 심폐소생술 교육 효과 평가)

  • Kim, Youl
    • The Korean Journal of Emergency Medical Services
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    • v.10 no.1
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    • pp.71-77
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    • 2006
  • This study is focused on middle school students who are composed of a factor in medical emergency system. In the case of cardiac failure, it is to make its basic data and develop its education program of CPR(cardiopulmonary resuscitation) which can increase the patient's survival rate before his hospitalization. The findings of this study is as follows. The subject of study is composed of 117 persons who are 54 boy-students(46.2%) and 63 girl-students(53.8%) in sex and 72 first-grade students(61.5%) and 45 second-grade students (38.5%) in a school year. In the accuracy degree, the practice of artificial respiration is $42.28{\pm}34.42%$ in case of basic CPR(cardiopulmonary resuscitation). The accuracy degree of the thorax pressure is $82.17{\pm}15.40%.$ In the accuracy degree, the practice of artificial respiration is $92.16{\pm}25.68%$ in boy-students and $20.38{\pm}24.16%$ in girl-students, the second-grade students is $58.40{\pm}33.29%$, which is higher than the first-grade students' $32.21{\pm}31.14%$. In the accuracy degree, the thorax pressure is $92.16{\pm}3.91%$ in boy-studetns and $73.61{\pm}16.41%$ in girl-students. In the accuracy degree of the thorax pressure, the second-grade students are $82.60{\pm}16.54%$ and the first-grade students $81.91{\pm}3.91$, which doesn't show any significant difference in school year. The satisfaction degree after theory & practice education is $2.12{\pm}.85$. In the satisfaction degree of its basic CPR, girl-students are $2.14{\pm}.83$ and boy-students are 2.11. In the satisfaction degree of its basic CPR, the second-grade students are $2.40{\pm}.61$ and the first-grade students are $1.95{\pm}.94$. This study is to lead to some suggestions. First, it is necessary to develop the education program and educate its knowledge & technology in proportion to student's characteristics of sex and school year. Second, education authorities should develop a subject of the accident prevention and first-aid treatment in its curriculum and provide the practical education of CPR for adults, adolescents and children. Third, it is necessary to study the education program as well as the education evaluation of CPR further on.

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Hemifacial Spasm Treated by Thread-embedding Therapy

  • Jung, Jae-eun;Jo, Na-Young;Roh, Jeong-Du
    • Journal of Acupuncture Research
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    • v.36 no.1
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    • pp.55-58
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    • 2019
  • The aim of this study was to investigate the efficacy of treatment with thread-embedding therapy for 24 patients with hemifacial spasm (HFS). The muscle spasm of these patients was treated with thread-embedding therapy. Patients with nuchal pain were treated with tendino-musculature acupuncture in the sternocleidomastoid, splenius, and trapezius muscles. We evaluated the treatment effect using the Scott's scale, where 20, 3, 1, and 0 patients presented Scott's grade 0, grade 1, grade 2, and grade 3, respectively. The grade of the spasm intensity decreased noticeably after treatment. The results revealed that the Scott's grade changed to 0 in 83.3% of HFS patients, and 91.7% patients felt satisfied with thread-embedding therapy. These findings suggested that thread-embedding therapy was effective and can be used widely for HFS.

Management of High-grade Blunt Renal Trauma

  • Lee, Min A;Jang, Myung Jin;Lee, Gil Jae
    • Journal of Trauma and Injury
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    • v.30 no.4
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    • pp.192-196
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    • 2017
  • Purpose: Blunt injury accounts for 80-95% of renal injury trauma in the United States. The majority of blunt renal injuries are low grade and 80-85% of these injuries can be managed conservatively. However, there is a debate on the management of patients with high-grade renal injury. We reviewed our experience of renal trauma at our trauma center to assess management strategy for high-grade blunt renal injury. Methods: We reviewed blunt renal injury cases admitted at a single trauma center between August 2007 and December 2015. Computed tomography (CT) scan was used to diagnose renal injuries and high-grade (according to the American Association for the Surgery of Trauma [AAST] organ injury scale III-V) renal injury patients were included in the analysis. Results: During the eight-year study period, there were 62 AAST grade III-V patients. 5 cases underwent nephrectomy and 57 underwent non-operative management (NOM). There was no difference in outcome between the operative group and the NOM group. In the NOM group, 24 cases underwent angioembolization with a 91% success rate. The Incidence of urological complications correlated with increasing grade. Conclusions: Conservative management of high-grade blunt renal injury was considered preferable to operative management, with an increased renal salvage rate. However, high-grade injuries have higher complication rates, and therefore, close observation is recommended after conservative management.