• 제목/요약/키워드: Grade 91

검색결과 418건 처리시간 0.029초

Association of tumor differentiation grade and survival of women with squamous cell carcinoma of the uterine cervix

  • Matsuo, Koji;Mandelbaum, Rachel S.;Machida, Hiroko;Purushotham, Sanjay;Grubbs, Brendan H.;Roman, Lynda D.;Wright, Jason D.
    • Journal of Gynecologic Oncology
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    • 제29권6호
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    • pp.91.1-91.12
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    • 2018
  • Objective: To examine the association between tumor grade and survival for women with squamous cervical cancer. Methods: This retrospective observational study utilized the Surveillance, Epidemiology, and End Result program data between 1983 and 2013 to examine women with squamous cervical cancer with known tumor differentiation grade. Multivariable analyses were performed to assess independent associations between tumor differentiation grade and survival. Results: A total of 31,536 women were identified including 15,175 (48.1%) with grade 3 tumors, 14,084 (44.7%) with grade 2 neoplasms and 2,277 (7.2%) with grade 1 tumors. Higher tumor grade was significantly associated with older age, higher stage disease, larger tumor size, and lymph node metastasis (all, p<0.001). In a multivariable analysis, grade 2 tumors (adjusted-hazard ratio [HR]=1.21; p<0.001) and grade 3 tumors (adjusted-HR=1.45; p<0.001) were independently associated with decreased cause-specific survival (CSS) compared to grade 1 tumors. Among the 7,429 women with stage II-III disease who received radiotherapy without surgical treatment, grade 3 tumors were independently associated with decreased CSS compared to grade 2 tumors (adjusted-HR=1.16; p<0.001). Among 4,045 women with node-negative stage I disease and tumor size ${\leq}4cm$ who underwent surgical treatment without radiotherapy, grade 2 tumors (adjusted-HR=2.54; p=0.028) and grade 3 tumors (adjusted-HR=4.48; p<0.001) were independently associated with decreased CSS compared to grade 1 tumors. Conclusion: Our study suggests that tumor differentiation grade may be a prognostic factor in women with squamous cervical cancer, particularly in early-stage disease. Higher tumor grade was associated with poorer survival.

Grade 91 강의 고온 균열진전 실험 결과와 설계 물성치의 비교 (Comparison of Crack Growth Test Results at Elevated Temperature and Design Code Material Properties for Grade 91 Steel)

  • 이형연;김우곤;김낙현
    • 대한기계학회논문집A
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    • 제39권1호
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    • pp.27-35
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    • 2015
  • 본 연구에서는 피로 하중 및 크리프 하중을 받는 Mod.9Cr-1Mo (ASME Grade 91)강 시편에 대한 일련의 실험결과로부터 재료물성치인 고온 균열진전 모델을 개발하였다. 이 균열진전 모델은 크리프-피로하중을 받는 균열체의 결함평가에 사용되는 물성치이다. 한국원자력연구원이 수행한 일련의 피로 균열진전(FCG) 속도 실험 및 크리프 균열진전(CCG) 속도 실험 결과로부터 균열진전 모델을 결정하고, 이를 프랑스의 고온 설계 기술기준인 RCC-MRx 와 비교함으로써 설계 물성치의 보수성에 대해 검토하였다. RCC-MRx 는 FCG 모델 및 CCG 모델을 Section III Tome 6 에서 제공하고 있는데, 실험으로부터 결정한 균열진전 모델과 비교한 결과 RCC-MRx 의 FCG 모델은 보수적인 것으로 나타난 반면 CCG 모델은 비보수적인 것으로 나타나 동 물성치에 대한 검증이 필요한 것으로 나타났다. 또한 본 연구에서는 기계적 강도 및 크리프 시험결과에 대해서도 RCC-MRx 의 물성치와 비교 및 분석하였다.

Grade 91 강의 장시간 크리프 수명 예측 방법 (Long-term Creep Life Prediction Methods of Grade 91 Steel)

  • 박재영;김우곤;;김선진;장진성
    • 동력기계공학회지
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    • 제19권5호
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    • pp.45-51
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    • 2015
  • Grade 91 steel is used for the major structural components of Generation-IV reactor systems such as a very high temperature reactor (VHTR) and sodium-cooled fast reactor (SFR). Since these structures are designed for up to 60 years at elevated temperatures, the prediction of long-term creep life is very important to determine an allowable design stress of elevated temperature structural component. In this study, a large body of creep rupture data was collected through world-wide literature surveys, and using these data, the long-term creep life was predicted in terms of three methods: Larson-Miller (L-M), Manson-Haferd (M-H) and Wilshire methods. The results for each method was compared using the standard deviation of error. The L-M method was overestimated in the longer time of a low stress. The Wilshire method was superior agreement in the long-term life prediction to the L-M and M-H methods.

Treatment Option for High Grade Spleen Injury and Predictive Factors for Non-operative Management

  • Na, Joung Won;Lee, Jung Nam;Yu, Byung Chul;Lee, Min A;Park, Jae Jung;Lee, Gil Jae
    • Journal of Trauma and Injury
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    • 제30권3호
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    • pp.91-97
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    • 2017
  • Purpose: Purpose: The prognostic factors of non-operative management (NOM) in high-grade spleen injuries have been extensively studied, but factors that would help treatment decisions are lacking. We compared the characteristics of the patients to identify the factors affecting treatment choices. Methods: This is a review of 207 blunt spleen injury patients from January 2004 to December 2013. We compared clinical features and mortality between surgery and NOM, and used multivariate regression analysis to find the factor most strongly associated with prognosis. Results: Of the 207 patients, 107 had high-grade spleen injury patents (grade III or above). Of these, 42 patients underwent surgery and 65 patients underwent NOM. The mortality was 7% following surgery, 3% with NOM. The amount of packed red blood cells transfused in the first 24 hours and spleen injury grade were associated with management type, and mortality was highly associated with activated partial thromboplastin time (aPTT) and spleen injury grade. Conclusions: The grade of spleen injury was associated with management and mortality, so correctly assessing the spleen injury grade is important.

Grade 91 강의 크리프 균열성장 거동에 대한 천이영역과 정상상태영역의 상관 관계 (Correlation Between Transient Regime and Steady-State Regime on Creep Crack Growth Behavior of Grade 91 Steel)

  • 박재영;김우곤;;김선진;김응선
    • 대한기계학회논문집A
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    • 제39권12호
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    • pp.1257-1263
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    • 2015
  • 제 4 세대 원자로의 고온 구조재료로 사되는 Grade 91 강의 크리프 균열성장 거동에 대한 천이영역과 정상상태영역에서의 상관 관계를 조사하였다. 이를 위해 $600^{\circ}C$의 동일한 온도 및 동일한 하중조건에서 1/2" CT 시편을 사하여 크리프 균열성장 시험 데이터를 얻었다. 크리프 균열성장 속도식은 $C^*$-파괴매개변수를 사하여 천이영역과 정상상태영역에서의 평가 식을 각각 도출하였다. $C^*$와 da/dt 의 관계에서 천이영역의 크리프 균열성장 속도는 시험 데이터의 산포가 크지만 정상상태영역의 크리프 균열성장 속도와 비슷한 기울기로서 상관성이 있었으며 천이영역 균열성장속도는 정상상태 균열성장속도에 비해 약 5.6 배 낮았다. 본 결과를 이하면 짧은 시간의 천이영역 균열성장속도로부터 장시간의 시험으로 얻을 수 있는 정상상태 균열성장속도를 예측할 수 있다.

간호대학생의 학년에 따른 대학적응과 생활 스트레스 비교연구 (A Comparative Study of College Adjustment and Life Stress of Nursing Students by Grades)

  • 정소영
    • 산업융합연구
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    • 제17권4호
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    • pp.139-146
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    • 2019
  • 본 연구는 간호대학생들의 학년에 따른 대학적응과 생활 스트레스를 비교하여 성공적인 대학적응 방안을 마련하기 위해 수행되었다. 본 연구는 서술적 연구로서, 경기도에 위치한 일개 대학의 간호학과에 재학 중인 1, 2, 3, 4학년 총 417명의 학생에게 온라인 설문조사를 진행하여 자료를 수집하였다. 수집된 자료는 SPSS WIN 20.0 프로그램을 사용하여 분석하였다. 연구결과 간호대학생의 대학적응은 4학년이(3.45±0.53), 1학년보다(3.18±0.61) 유의하게 높은 것으로 나타났고, 생활 스트레스는 1학년이 가장 높았고(0.91±0.46), 4학년, 2학년 3학년 순으로 나타났다. 학년에 따른 대학적응과 생활 스트레스는 각 학년에서 역 상관관계를 보였다. 따라서, 본 연구결과에서 나타난 학년에 따른 대학적응 및 생활 스트레스의 하위요소별 차이를 토대로, 학년의 특성에 맞는 맞춤형 프로그램을 마련하여 간호대학생의 스트레스 관리를 통해 대학적응을 잘할 수 있도록 노력해야 할 것이다.

Microstructural Evolution of Grade 91 Steel upon Heating at 760~1000℃

  • He, Yinsheng;Chang, Jungchel;Lee, Je-Hyun;Shin, Keesam
    • 한국재료학회지
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    • 제25권11호
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    • pp.607-611
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    • 2015
  • The microstructural evolution of Grade 91 tempered martensite ferritic steels heat treated at $760{\sim}1000^{\circ}C$ for two hours was investigated using scanning electron microscopy(SEM), energy disperse spectroscopy(EDS), electron backscattered diffraction (EBSD), and transmission electron microscopy(TEM); a microhardness tester was also employed, with a focus on the grain and precipitate evolution process as well as on the main hardening element. It was found that an evolution of tempered martensite to ferrite($760{\sim}850^{\circ}C$), and to fresh martensite($900{\sim}1000^{\circ}C$), occurred with the increase of temperature. Simultaneously, the parabolic evolution characteristics of the low angle grain boundary(LAGB) increased with the increase of the heating temperature(highest fraction of LAGB at $925^{\circ}C$), indicating grain recovery upon intercritical heating. The main precipitate, $M_{23}C_6$, was found to be coarsened slightly at $760{\sim}850^{\circ}C$; it then dissolved at $850{\sim}1000^{\circ}C$. Besides this, $M_3C$ cementite was formed at $900{\sim}1000^{\circ}C$. Finally, the experimental results show that the hardness of the steel depended largely on the matrix structure, rather than on the precipitates, with the fresh martensite showing the highest hardness value.

중학교 재학생의 기본 심폐소생술 교육 효과 평가 (The education evaluation of basic CPR on middle school students)

  • 김율
    • 한국응급구조학회지
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    • 제10권1호
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    • pp.71-77
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    • 2006
  • This study is focused on middle school students who are composed of a factor in medical emergency system. In the case of cardiac failure, it is to make its basic data and develop its education program of CPR(cardiopulmonary resuscitation) which can increase the patient's survival rate before his hospitalization. The findings of this study is as follows. The subject of study is composed of 117 persons who are 54 boy-students(46.2%) and 63 girl-students(53.8%) in sex and 72 first-grade students(61.5%) and 45 second-grade students (38.5%) in a school year. In the accuracy degree, the practice of artificial respiration is $42.28{\pm}34.42%$ in case of basic CPR(cardiopulmonary resuscitation). The accuracy degree of the thorax pressure is $82.17{\pm}15.40%.$ In the accuracy degree, the practice of artificial respiration is $92.16{\pm}25.68%$ in boy-students and $20.38{\pm}24.16%$ in girl-students, the second-grade students is $58.40{\pm}33.29%$, which is higher than the first-grade students' $32.21{\pm}31.14%$. In the accuracy degree, the thorax pressure is $92.16{\pm}3.91%$ in boy-studetns and $73.61{\pm}16.41%$ in girl-students. In the accuracy degree of the thorax pressure, the second-grade students are $82.60{\pm}16.54%$ and the first-grade students $81.91{\pm}3.91$, which doesn't show any significant difference in school year. The satisfaction degree after theory & practice education is $2.12{\pm}.85$. In the satisfaction degree of its basic CPR, girl-students are $2.14{\pm}.83$ and boy-students are 2.11. In the satisfaction degree of its basic CPR, the second-grade students are $2.40{\pm}.61$ and the first-grade students are $1.95{\pm}.94$. This study is to lead to some suggestions. First, it is necessary to develop the education program and educate its knowledge & technology in proportion to student's characteristics of sex and school year. Second, education authorities should develop a subject of the accident prevention and first-aid treatment in its curriculum and provide the practical education of CPR for adults, adolescents and children. Third, it is necessary to study the education program as well as the education evaluation of CPR further on.

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Hemifacial Spasm Treated by Thread-embedding Therapy

  • Jung, Jae-eun;Jo, Na-Young;Roh, Jeong-Du
    • Journal of Acupuncture Research
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    • 제36권1호
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    • pp.55-58
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    • 2019
  • The aim of this study was to investigate the efficacy of treatment with thread-embedding therapy for 24 patients with hemifacial spasm (HFS). The muscle spasm of these patients was treated with thread-embedding therapy. Patients with nuchal pain were treated with tendino-musculature acupuncture in the sternocleidomastoid, splenius, and trapezius muscles. We evaluated the treatment effect using the Scott's scale, where 20, 3, 1, and 0 patients presented Scott's grade 0, grade 1, grade 2, and grade 3, respectively. The grade of the spasm intensity decreased noticeably after treatment. The results revealed that the Scott's grade changed to 0 in 83.3% of HFS patients, and 91.7% patients felt satisfied with thread-embedding therapy. These findings suggested that thread-embedding therapy was effective and can be used widely for HFS.

Management of High-grade Blunt Renal Trauma

  • Lee, Min A;Jang, Myung Jin;Lee, Gil Jae
    • Journal of Trauma and Injury
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    • 제30권4호
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    • pp.192-196
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    • 2017
  • Purpose: Blunt injury accounts for 80-95% of renal injury trauma in the United States. The majority of blunt renal injuries are low grade and 80-85% of these injuries can be managed conservatively. However, there is a debate on the management of patients with high-grade renal injury. We reviewed our experience of renal trauma at our trauma center to assess management strategy for high-grade blunt renal injury. Methods: We reviewed blunt renal injury cases admitted at a single trauma center between August 2007 and December 2015. Computed tomography (CT) scan was used to diagnose renal injuries and high-grade (according to the American Association for the Surgery of Trauma [AAST] organ injury scale III-V) renal injury patients were included in the analysis. Results: During the eight-year study period, there were 62 AAST grade III-V patients. 5 cases underwent nephrectomy and 57 underwent non-operative management (NOM). There was no difference in outcome between the operative group and the NOM group. In the NOM group, 24 cases underwent angioembolization with a 91% success rate. The Incidence of urological complications correlated with increasing grade. Conclusions: Conservative management of high-grade blunt renal injury was considered preferable to operative management, with an increased renal salvage rate. However, high-grade injuries have higher complication rates, and therefore, close observation is recommended after conservative management.