• Title/Summary/Keyword: Glycerin Solution

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Effects of Glycerin and PEG 400 in Donor and Receptor Solutions upon Skin Permeation of Drug (In vitro 경피흡수 실험시 Donor와 Receptor용액중의 글리세린과 PEG 400이 약물의 경피투과도에 미치는 영향)

  • Cho, Ae-Ri
    • Journal of Pharmaceutical Investigation
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    • v.26 no.2
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    • pp.99-103
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    • 1996
  • Effects of glycerin and PEG 400 in donor and receptor solutions upon skin permeation of drug were investigated. Deoxycortisone was used as a model compound. In vitro skin permeation study with freshly excised hairless mouse skin was performed and the steady-state skin permeation rates of the drug were determined in different fractions of glycerin or PEG 400 in donor and receptor solutions. Glycerin in donor solution didn't show any effect on the skin permeation rate of deoxycortisone. However glycerin in receptor solution showed significant effect on the skin permeation rate of the drug. In glycerin, there's a critical concentration for balancing hydration and dehydration of skin. At low concentration, less than 20 %, glycerin showed the enhancement of the flux due to the hydration effect of skin. At high concentration, more than 30 %, glycerin retard the permeation rate which might be due to the dehydration effect on the dermis layer. Since dermis has more water content than the stratum corneum, the steady state skin permeation rates were more influenced when glycerin was in receptor solution than that of in donor solution. PEG 400 aqueous solutions doesn't affect the steady state permeation rate of deoxycortisone significantly.

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Pump Performance Analyses with High Viscosity Fluids (고점성용 펌프의 성능해석)

  • Roh, Hyung-Woon;Suh, Sang-Ho;Kim, Dong-Joo;Kim, Young-Dae
    • 유체기계공업학회:학술대회논문집
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    • 2003.12a
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    • pp.367-370
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    • 2003
  • In this study the effects of fluid viscosity on the pump performances of a conventional centrifugal pump were experimentally studied. The study aimed to compare the pump characteristics for water and high viscosity fluids. The Working fluids are water, aqueous sugar solution and glycerin solution. The pump characteristics of total head and efficiency with high viscosity fluids were different. The performance curves of efficiency for the sugar and glycerin solutions were decreased up to 8.1% and 12.9% than that of water.

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Examination of Spread-Recoil Behavior of a Shear-thinning Liquid Drop on a Dry Wall (전단희석 액적의 건조 벽면 충돌 후 전개-수축 거동의 관찰)

  • An, Sang-Mo;Lee, Sang-Yong
    • Journal of ILASS-Korea
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    • v.14 no.3
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    • pp.131-138
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    • 2009
  • In the present study, spread-recoil behavior of a drop of shear-thinning liquid (xanthan solution) on a dry wall (polished stainless-steel plate) was examined and compared with that of Newtonian liquid (glycerin solution). Nine different kinds of xanthan and glycerin solutions were tested, including three pairs of xanthan and glycerin solutions, each having the same viscosity in low shear rate region ($10^{-2}-10^0\;l/s$). The drop behavior was visualized and recorded using a CCD camera. The maximum diameter and the spreading velocity of the xanthan drops turned out to be significantly larger and the time to reach their final shape was much shorter compared to the cases with the glycerin solutions, due to the smaller viscous dissipation resulted from lower viscosity in the higher shear rate region (>$10^0\;l/s$). As a result, the maximum diameters were measured to be larger than the predicted values based on the model proposed for Newtonian liquids, and the deviation was more pronounced with the solution with the larger viscosity variation. Consequently, viscosity variation with the shear rate was found to be a dominant factor governing the spread-recoil behavior of shear-thinning drops.

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Preparation and Characterization of Poly(vinyl alcohol)/Poly(N-vinylpyrrolidone)/Glycerin/Chitosan Hydrogels by Radiation (방사선 가교에 의해 제조된 Poly(vinyl alcohol)/Poly(N-vinylpyrrolidone)/글리세린/키토산 하이드로겔의 제조 및 특성)

  • 박경란;노영창
    • Polymer(Korea)
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    • v.26 no.6
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    • pp.792-802
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    • 2002
  • In this study, hydrogels from mixtures of poly (vinyl alcohol) (PVA)/poly(N-vinylpyrrolidone) (PVP)/glycerin/chitosan were prepared by γ-ray irradiation and the mechanical properties such as gelation, water absorptivity, and gel strength were examined to evaluate the applicability of these for wound dressing. Then PVA:PVP was weight ratio of 6 : 4, the concentration of chitosan was 0.3 wt%, the concentration of glycerin was in the range of 0∼5 wt%t. The solid concentration of PVA/PVP/glycerin/chitosan solution was 15 wt%. Gamma irradiation doses of 25, 35, 50, and 60 kGy were exposed to a mixture of PVA/PVP/glycerin/chitosan to evaluate the effect of irradiation dose. Gel content and gel strength increased as glycerin concentration in PVA/PVP/glycerin/chitosan decreased, and as irradiation dose increased. Swelling degree increased as glycerin concentration in PVA/PVP/glycerin/chitosan increased, and as irradiation dose decreased. The glycerin in PVA/PVP/glycerini/chitosan hydrogel prevented the transformation of shape. These hydrogel dressings had better curing effect than vaseline gauge.

Comparison of Centrifugal Pump Performances for Newtonian and Non-Newtonian Fluids (뉴턴유체와 비뉴턴유체의 원심펌프성능특성 비교)

  • Kim, Dong-Joo;Roh, Hyung-Woon;Suh, Sang-Ho
    • 유체기계공업학회:학술대회논문집
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    • 2004.12a
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    • pp.57-62
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    • 2004
  • In the current study the effects on pump performances of a conventional centrifugal pump for Newtonian and non-Newtonian fluid were experimentally studied. The study aimed to compare the pump characteristics for Newtonian and non-Newtonian fluid. The working fluids are water, aqueous sugar solution, glycerin solution, muddy solution and pulp solution. The pump characteristics with high viscosity fluids were different. The operating efficiency for the sugar and glycerin solutions were decreased to $8.1\%$ and $12.9\%$ than that of water. The head reductions of the muddy solution for different concentration ratios were decreased to $7.97\%,\;15.11\%$ and $24.87\%$ than that of water And the head reductions of the pulp solution for different concentration ratios were decreased to $11.87\%,\;19.79\%$ md $36.81\%$ than that of water.

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A Case of Ischemic Colitis Presenting as Bloody Diarrhea after Glycerin Enema in a Patient on Modified Fasting Therapy (절식요법 중 글리세린 관장 직후 혈성 설사로 발현한 허혈성 대장염 1예)

  • Choi, Hyo-Jeong;Park, Hyun-Gun;Maeng, Tae-Ho;Yoo, Duk-Joo;Kim, Sung-Soo;Chung, Won-Suk
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.2
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    • pp.185-191
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    • 2013
  • Case of ischemic colitis after enema for bowel cleansing have been rarely reported, but there has been no case report of a patient on modiefied fasting therapy. A 26-year old male patient with obesity admitted Korean medical hospital of Kyung Hee university for losing weight. He is on a special diet called modiefied fasting therapy, only took the fermented herbal drink. At 2nd day, he received an enema for bowel cleansing. A few hours after enema, he had a bloody diarrhea with lower abdominal pain. His colonoscopic and histologic findings presented ischemic colitis. He was advised to fast for two days and couldn't complete his diet program. We suggest 4 possible reasons : Increased intraluminal pressure by enema, vascular spasm caused by room-temperature glycerin solution colder than intraluminal temperature, predisposition to bleeding disturbances by taking selective serotonin reuptake inhibitor(SSRI) for depression history and mucosal injury by osmotic effect of glycerin solution itself. For reducing the risk of bowel cleansing, glycerin enema should be carefully prescribed and practiced concerning the condition of each patient.

Comparative analysis of glycerin in cosmetics by LC/MS and 1H NMR (LC/MS와 1H NMR을 이용한 화장품속의 글리세린 비교분석)

  • Park, Gyo-Beom;Park, Chan Jo;Lee, Sueg-Geun
    • Analytical Science and Technology
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    • v.20 no.5
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    • pp.400-405
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    • 2007
  • The comparative analysis of glycerin in cosmetic samples was carried out by LC/MS and $^1H$ NMR spectrometry. For the LC/MS analysis, aqueous solution was controlled in strong basic condition with sodium hydroxide, and benzoyl chloride was added to the solution for the derivatization of glycerin. The derivative was extracted using pentane and analyzed by the LC/MS. For the $^1H$ NMR analysis, sample was directly dissolved in $D_2O$ solvent without pretreatment. The quantitative analysis of glycerin was done by $^1H$ NMR ERETIC method. The analysis results of LC/MS and $^1H$ NMR showed that the calibration curves were a good linearity with $r^2=0.9991$ in the range of 0.1 to $10{\mu}g/mL$ and $r^2=1$ in the range of 25 to $500{\mu}g/mL$, respectively.

Pump Performance Analyses with High Viscous Fluids (점성이 높은 유체를 사용하는 펌프의 성능해석)

  • Kim, Dong-Joo;Roh, Hyung-Woon;Suh, Sang-Ho
    • The KSFM Journal of Fluid Machinery
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    • v.7 no.2 s.23
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    • pp.21-26
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    • 2004
  • In this study the effects of fluid viscosity on the pump performances for a conventional centrifugal pump were experimentally investigated. The study aimed to compare the pump characteristics between water and viscosity fluids. In order to measure the flow rate and pressure, v-notch welt and bourdon pressure gauges were used for the codes of KS B6301 and KS B6302. The working fluids were water, aqueous sugar and glycerin solutions. The results were summarized as follows : The experimental results were summarized as follows : the pump characteristics of the total head, shaft power, and efficiency with high viscosity fluids were different from those of water. When the viscosity of the applied fluid was increased, the total head and efficiency were more decreased than those of water. The decreasing gradients of the total head and the efficiency were larger than water due to the increased disk friction losses at the duty operation point. However, the shut-off head was almost constant regardless the viscosity of applied fluids. Each efficiency curves for the sugar $20w\%$ and glycerin $20w\%$ solutions was decreased up to $15.1\%$ and $34.4\%$ than that of water, respectively.

Biodiesel Refining and Glycerin Recovering Process of Transesterification from Tra Catfish Fat

  • Huong, Le Thi Thanh;Tan, Phan Minh;Hoa, Tran Thi Viet;Lee, Soo
    • Journal of the Korean Applied Science and Technology
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    • v.26 no.1
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    • pp.1-9
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    • 2009
  • Nowadays, Tra catfish fat is given attention as an appropriate material for biodiesel production in Vietnam. The aim of this work is to investigate the optimal conditions of refining biodiesel and recovering glycerin by the transesterification from Tra catfish fat using KOH catalyst. As our results, the yield of transesterification was achieved to 94.17% at $50^{\circ}C$ for 45 min with 6:1 molar ratio of methanol to fat in the presence of 0.8% KOH catalyst, and wherein the biodiesel was refined by washing with distilled water at $70^{\circ}C$ and dried in a microwave oven. The yield of raw glycerin recoveries from the transesterification process was 78.58%. The purity of raw glycerin was 84.14% by the conditions of neutralization state with $H_{3}PO_{4}$ solution (pH = 5), $70^{\circ}C$, and 60 min. Activated carbon (3.0 wt.%) was used for the bleaching process at $80^{\circ}C$ for 20 min. The biodiesel was obtained in accordance with for ASTM D 6751 (biodiesel standard). The ash and water of raw glycerins were 7.32 and 8.01%, respectively, and implied that the raw glycerin is very promising candidate to be used as a raw material for textile and cosmetic industries.

Preparation of high-performance nanofiltration membrane with antioxidant properties

  • Yu, Feiyue;Zhang, Qinglei;Pei, Zhiqiang;Li, Xi;Yang, Xuexuan;Lu, Yanbin
    • Membrane and Water Treatment
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    • v.13 no.4
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    • pp.191-199
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    • 2022
  • In industrial production, the development of traditional polyamide nanofiltration (NF) membrane was limited due to its poor oxidation resistance, complex preparation process and high cost. In this study, a composite NF membrane with high flux, high separation performance, high oxidation resistance and simple process preparation was prepared by the method of dilute solution dip coating. And the sulfonated polysulfone was used for dip coating. The results indicated that the concentration of glycerin, the pore size of the based membrane, the composition of the coating solution, and the post-treatment process had important effects on the structure and performance of the composite NF membrane. The composite NF membrane prepared without glycerol protecting based membrane had a low flux, when the concentration of glycerin increased from 5% to 15%, the pure water flux of the composite NF membrane increased from 46.4 LMH to 108.2 LMH, and the salt rejection rate did not change much. By optimizing the coating system, the rejection rate of Na2SO4 and PEG1000 was higher than 90%, the pure water flux was higher than 40 LMH (60psi), and it can withstand 20,000 ppm.h NaClO solution cleaning. When the post treatment processes was adjusted, the salt rejection rate of NaCl solution (250 ppm) reached 45.5%, and the flux reached 62.2 LMH.