• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2002년도 추계학술발표논문집 (중)
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• pp.1495-1498
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• 2002

최근 지리적으로 분산된 고성능 컴퓨터 자원을 네트워크로 상호 연동하여 사용할 수 있도록 하는 그리드 연구가 활발히 진행하고 있다. 본 논문에서는 Globus 툴킷에서 사용자에게 자원의 상태 정보를 서비스하는 MDS (Metacomputing Directory Service)에 링크의 대역폭이나 지연 시간 등의 네트워크 자원 정보를 제공하는 네트워크 정보 제공자를 개발한다. 이를 위해 Globus 툴킷의 MDS와 NWS 시스템을 분석하고, 이를 바탕으로 NWS의 센서 부분을 이용하여 네트워크 정보 스키마 정의, 정보 제공자 프로그램 작성, MDS 구성 파일 수정 등을 통해 네트워크 정보 제공자를 구현한다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2005년도 한국컴퓨터종합학술대회 논문집 Vol.32 No.1 (A)
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• pp.7-9
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• 2005

그리드 컴퓨팅을 실현하기 위해서는 Virtual Organization을 구성하는 개인, 기관, 그리고 자원 등의 동적인 집합에 대해 유연하고 안정적이며 통합된 자원의 공유를 구현해야 한다. 이를 위해 해결해야 할 많은 과제들 중에는 인증과 권한 부여가 있으며 이 두 가지는 단일시스템의 계정관리에 속한다. 현재 그리드 컴퓨팅을 실현하기 위한 많은 middleware들 중에서 확고한 위치를 차지하고 있는 Globus Toolkit은 grid-mapfile을 이용하여 정적인 사용자 계정관리를 하기 때문에 동적 특성을 가진 그리드 컴퓨팅에는 적합하지 않다. 따라서 본 논문에서는 그리드 컴퓨팅을 위한 사용자 계정관리시스템에 대한 기존의 연구를 토대로 그리드 사용자 계정관리시스템을 Globus Toolkit 3.2를 기반으로 설계하였다.

• 대한한방내과학회지
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• 제43권6호
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• pp.1301-1310
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• 2022

Objective: The purpose of this case study was to report the effects of Korean medicine treatment on a patient diagnosed with postgastrectomy syndrome (PGS). Methods: The patient was treated with herbal medicine, acupuncture, and moxibustion in combination with Western medicine for 3 months. Results: Though abdominal tenderness was maintained at a similar level, other clinical symptoms (epigastric pain, globus pharyngis, and epigastric pain) were improved after Korean medicine treatment. Conclusions: These results suggest that the need to promote practical research on PGS, should receive greater attention in the Korean medical community.

• 대한핵의학회지
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• 제22권2호
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• pp.163-170
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• 1988

8 patients of delayed CO sequelae were evaluated using Brain CT and $^{99m}Tc-HMPAO$ SPECT. The results were as follows; 1) CT findings of delayed CO sequleae were bilateral low density lesion in globus pallidus (l pt.), diffuse low density in white matter with bilateral low density in white matter (l pt.), diffuse low density in white matter with bilateral low density in globus pallidus (l pt.), diffuse low density in white matter with cortical atrophy (l pt.), bilateral low density in globus pallidus and diffuse low density in white matter with cortical atrophy (l pt.) and normal in 3 pts. 2) $^{99m}Tc-HMPAO$ Brain SPECT findings of delayed CO sequelae were decreased regional cerebral blood flow (rCBF) in frontal (1 among 8 pts.), frontal and basal ganglia (3 among 8 pts.), and diffuse patch decreased rCBF pattern (4 among 8 pts.) 3) $^{99m}Tc-HMPAO$ Brain SPECT study was well correlated with neurologic symptoms and signs in delayed CO sequelae. Our results may suggest that reduced cerebral blood flow contributes to the development of delayed CO sequelae.

• The Korean Journal of Physiology and Pharmacology
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• 제17권4호
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• pp.299-306
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• 2013

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been widely used as a treatment for the movement disturbances caused by Parkinson's disease (PD). Despite successful application of DBS, its mechanism of therapeutic effect is not clearly understood. Because PD results from the degeneration of dopamine neurons that affect the basal ganglia (BG) network, investigation of neuronal responses of BG neurons during STN DBS can provide informative insights for the understanding of the mechanism of therapeutic effect. However, it is difficult to observe neuronal activity during DBS because of large stimulation artifacts. Here, we report the observation of neuronal activities of the globus pallidus (GP) in normal and PD model rats during electrical stimulation of the STN. A custom artifact removal technique was devised to enable monitoring of neural activity during stimulation. We investigated how GP neurons responded to STN stimulation at various stimulation frequencies (10, 50, 90 and 130 Hz). It was observed that activities of GP neurons were modulated by stimulation frequency of the STN and significantly inhibited by high frequency stimulation above 50 Hz. These findings suggest that GP neuronal activity is effectively modulated by STN stimulation and strongly dependent on the frequency of stimulation.

• 대한기관식도과학회지
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• 제9권1호
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• pp.67-74
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• 2003

Larygopharyngeal reflux(LPR) is one form of the Gastroesophageal Reflux Diseases(GERD). It is known to cause various kinds of otolaryngologic symptoms such as hoarseness, globus sensation in throat, chronic throat clearing, and chronic cough, Disease entities diagnosed by otolaryngologists as posterior laryngitis, globus pharyngeus and reflux laryngitis should be suspected as LPR-related diseases. The nizatidine(AXID), as a Histamine H2-receptor antagonist, reduces gastric acid secretion and improves gastric motility function. Objectives : The effect of nizatidine using 150mg b.i.d was evaluated for symptom relief and improvement of laryngoscopic findings in patients with LPR. Materials and Methods : In 30 multicenter, observational trial performed nationalwidely in Korea. 308 patients with LPR symptom were observed to evaluate their symptoms and larygnoscopic findings after 4weeks, 8weeks, 12weeks of treatment with nizatidine. Results : The symptoms of LPR including globus sensation, chronic throat clearing and hoarseness, are reduced significantly after 4 weeks, 8weeks, and 12weeks of treatment(p<0.05). The laryngoscopic findings including diffuse erythema, edema and granulation are improved after nizatidine treatment(p<0.05). and the efficacy of nizatidine on LPR-related sympoms after 4 weeks is 88.6%, and those of after 8 weeks and 12weeks were 92.6%, and 99.1% in ITT(Intent To Treatment) group(p<0.05). And PPA(Per Protocol Analysis)group showed 93.7%, 97.3%, and 99.1% of efficacy after 4, 8, and 12 weeks of nizatidine treatment(p<0.05). Conclusion : These results indicate that in patient with LPR, nizatidine 150mg b.i.d treatment very effectively reduces LPR symptoms and improves laryngoscopic findings as well as reduces gastric acid secretion and improves gastric motility function.

• 한국패류학회지
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• 제17권2호
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• pp.105-115
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• 2001

국내에 서식하는 다슬기 과의 곳체다슬기 (Semisulcospira gottschei), 참다슬기 (S. coreana), 주름다슬기 (S. forticosta), 좀주름다슬기 (S. tegulata), 다슬기 (S. ibertina), 염주알다슬기 (Koreanomelania nodifila), 띠구슬다슬기 (Koreoleptoxis globus ovalis)의 치설을 광학현미경과 주사전자현미경을 이용하여 관찰하였다. 다슬기과 담수패류의 치설은 모두 한 열 (transverse row)에 7개 (M+2L+4M)의 이빨을 갖는 리본 모양의 유설형(taenioglossa)이다. Semisulcospira 속의 5 종 (곳체다슬기, 참다슬기, 주름다슬기, 좀주름다슬기, 다슬기)의 중치는 3 + 1 + 3 또는 2 + 1 + 2의 치첨수 배열을 이루는 대칭구조를 보이며 평균 98-112 개의 치열로 구성되어 있다. 염주알다슬기(Koreanomelania nodifila)의 중치는 2 + 1 + 2의 치첨수 배열을 이루는 대칭구조를 보이며 평균 118 개의 치열로 구성되어 있다. 띠구슬다슬기 (Koreoleptoxis globus ovalis)는 3 + 1 + 3의 치첨수 배열을 이루는 대칭구조를 보이며 평균 213 개의 치열로 구성되어 있다. 이상의 결과 다슬기과 7종의 치설 구조는 뚜렷한 속간 차이를 나타내었으나 종간 구조적 차이는 발견되지 않았다.

• 사상체질의학회지
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• 제24권3호
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• pp.93-103
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• 2012

Objectives Rate of gastroesophageal reflux disease accompanied by irritable bowel syndrome is on the increase. This case study reports significant improvement of patients with gastroesophageal reflux disease and irritable bowel syndrome who had suffered from chest pain, globus pharyngis and diarrhea after taking Sasang constitutional treatment. Methods This patient was diagnosed as Large Yin type Esophagus Cold pattern(Taeeumin Wiwanhanjeung). Herb medicine(Jowiseungcheong-tang) was taken by the patient, three or two times per day during treatment periods. We assessed the changes of the main symptoms such as chest pain, globus pharyngis, defecation discomfort, insomnia et al. using visual analogue scale(VAS). Results The symptoms of chest pain, globus pharyngis, defecation discomfort, insomnia decreased from VAS 7~8 to VAS 0~1 for about three months. Conclusions This case shows that Sasang constitutional medicine treatment can be effective treatment method for gastroesophageal reflux disease accompanied by irritable bowel syndrome.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제11권6호
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• pp.465-476
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• 2005

본 논문에서는 Cactus와 Globus 기반의 그리드 컴퓨팅 환경에서 응용프로그램 수준의 체크 포인팅을 사용한 동적 재구성(Dynamic Reconfiguration) 기법을 새로이 제안하였다. 기존의 동적 재구성은 특정 하드웨어와 운영체제에 종속적이었으나 제안한 방법은 특정 하드웨어와 운영체제의 지원 없이 동적재구성이 가능하고 응용프로그램도 동적 재구성을 고려할 필요 없이 프로그래밍이 가능하다. 제안한 동적 재구성 기법에서 초기 연산자원의 구성을 갖고 실행되는 작업은 실행 중에 동적으로 발견된 새로운 연산자원을 포함하여 계속 연산을 수행한다. 본 연구에서 제안된 방법은 새롭게 발견된 연산자원의 프로세서 성능과 유휴 메모리를 고려하여, 해당 연산자원을 수행중인 연산에 포함할 것인가 여부를 결정한다 연산중 연산 결과의 실시간 가시화를 가능하도록 하고 운영체제에 종속적이지 않은 응용프로그램 수준의 체크 포인팅 기법을 사용하여 중간 연산결과를 저장한다. 새롭게 발견된 유휴사이트, 유휴프로세서를 포함하도록 연산자원의 구성을 재구성한 후 체크 포인팅 파일을 사용하여 작업을 계속 실행한다. 제안한 동적 재구성 기법은 K*Grid 환경에서 연산시간을 단축함을 확인하였다.

• 대한기관식도과학회지
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• 제15권1호
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• pp.41-49
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• 2009

Background and Objectives : Proton pump inhibitors(PPIs) improve the symptoms of laryngopharyngeal reflux(LPR). But there is little reports about the changes of each items in reflux symptom index (RSI) and reflux finding score (RFS) after PPIstreatment. The purpose of this study is to analyze the changes of pre- and post-treatment score in each RSI and RFS items after 8 weeks medication with proton pump inhibitors in laryngopharyngeal reflux patients. Methods : Prospective study. Among the patients who had visited the department of otolaryngology from January 2007 to December 2008, 91 patients who had shown scores greater than 13 on the RSI and/or 7 on the RFS were studied. All patients received PPIs once daily before breakfast for 8 weeks. RSI and RFS were assessed at initial, four weeks and eight weeks after medication. Result: All RSI items were improved (p < 0.05). The globus sense followed by throat clearing, heartburns and hoarseness showed high initial RSI score than other items. And globus sense, throat clearing, hoarseness and heartburn were improved significantly more than others items. But only posterior commissure hypertrophy of RFS was improved significantly more than others items. Conclusion: Empiric PPIs therapy reduced the RSI scores and more effective for symptoms such as globus sense, throat clearing, hoarseness and heartburn among suspected LPR patients. In RFS, only posterior commissure hypertrophy has improved significantly. However, the changes of each categories of RFS were minimal (average: 0.16), therefore clinical significance is restricted in RFS.