• Journal of the Economic Geographical Society of Korea
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• v.18 no.1
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• pp.1-16
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• 2015

It is widely believed that increasing socio-economic polarization inspired by globalization and economic restructuring worsens residential segregation by class in Korean cities. However, the existing literature falls short in showing the recent changes of the residential segregation, particularly after the 1997 financial crisis, with reliable and systematic segregation measures. Noting that there are the two major dimension in residential segregation - evenness-concentration and exposure-clustering - this study introduced not only global measure (dissimilarity index and isolation/interaction index) but also local measures (location quotient and Local Moran's I) for each dimension. These measures are applied to the case study of Seoul in the 2000s. The class is defined by education attainment and the data is obtain through the MicroData System Service System(MDSS). The result shows that the residential segregation by education attainment persists through 2000s and even get worse in some dimension. More significantly, it turns out that high-class and low-class residence are nearly mirror-images of each other, indicating high segregation.

• Interdisciplinary Bio Central
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• v.3 no.4
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• pp.14.1-14.9
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• 2011

Protein homology detection is an important issue in comparative genomics. Because of the exponential growth of sequence databases, fast and efficient homology detection tools are urgently needed. Currently, for homology detection, sequence comparison methods using local alignment such as BLAST are generally used as they give a reasonable measure for sequence similarity. However, these methods have drawbacks in offering overall sequence similarity, especially in dealing with eukaryotic genomes that often contain many insertions and duplications on sequences. Also these methods do not provide the explicit models for speciation, thus it is difficult to interpret their similarity measure into homology detection. Here, we present a novel method based on Word Conservation Score (WCS) to address the current limitations of homology detection. Instead of counting each amino acid, we adopted the concept of 'Word' to compare sequences. WCS measures overall sequence similarity by comparing word contents, which is much faster than BLAST comparisons. Furthermore, evolutionary distance between homologous sequences could be measured by WCS. Therefore, we expect that sequence comparison with WCS is useful for the multiple-species-comparisons of large genomes. In the performance comparisons on protein structural classifications, our method showed a considerable improvement over BLAST. Our method found bigger micro-syntenic blocks which consist of orthologs with conserved gene order. By testing on various datasets, we showed that WCS gives faster and better overall similarity measure compared to BLAST.

• Health Policy and Management
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• v.31 no.3
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• pp.244-254
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• 2021

The management of emerging infectious diseases cannot help but completely depend on non-pharmaceutical interventions in the early stages of the outbreak. Consequently, South Korea has developed and implemented the 3T (test-trace-treat) models, non-pharmaceutical infection prevention and control (IPC) measures, in response to the coronavirus disease 2019 (COVID-19) pandemic. The IPC measures have gained global attention, rendering them to be essential in the development of a shareable, reusable, and applicable protocol for future pandemics. This study was conducted to identify the requirements necessary for standardizing the IPC measures. Three new work items of the 18 3T models were proposed to ISO/TC 304 (International Organization for Standardization/Technical Committee 304; healthcare organization management). Requirements for each IPC measure, identified by participating members (P-members) countries during the ISO ballots, were analyzed in this study. The three new work items were approved by the P-members countries after a 3-month ballot. There was a consensus that the three IPC measure models should be International Standards (IS). Other comments include (1) the models should include not only COVID-19 but also any respiratory pandemic; and (2) keep donning of level D protection at screening sites as an optional protocol, in consideration for the lack of personal protective equipment. Standardization is a systematic process of developing internationally agreed-upon wisdom and knowledge that consider and respect the diversity and universality of each country. It is expected that such standardized applicable IPC measure models contribute to global efforts to rapidly respond to a public health emergency of international concern during its early stages.

• Journal of Korea Trade
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• v.26 no.3
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• pp.45-62
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• 2022

Purpose - Using unexpected changes in geopolitical tensions on the Korean peninsula as a quasi-natural experimental setting, we examine whether and how geopolitical risks travel across borders through firm-level imports and exports linkages. We also test whether the effects are driven by either imports or exports and assess whether firms can effectively hedge themselves against geopolitical risks. Design/methodology - We focus on a series of unanticipated geopolitical events taken place in Korea in 2018. Making use of the shocks to geopolitical climate, we identify five milestone events toward peace talks. We employ the event studies methodology. We examine heterogenous firm-level stock price reactions around key event dates depending on firms' exposure to geopolitical risks. As a measure of firms' exposure to geopolitical risks in Korea, we utilize a text-based measure of firm-level trade links. When a firm announces and discusses its purchase of inputs from Korea or sales of outputs to Korea in their annual disclosure filings, we define a firm to have a trade relationship with Korea and have exposure to Korean geopolitical risks. Similarly, we use a measure of a firm's hedging policies based on a firm's textual mention of the use of foreign exchange derivatives in their annual disclosure. Findings - We find that U.S. firms that have direct trade links to Korea gained significantly more value when the intensity of geopolitical risks drops compared to firms without such trade links to Korea. The effects are pronounced for firms purchasing inputs from or selling outputs to Korea. We find that the effectiveness of foreign exchange hedging against geopolitical risks is limited. Originality/value - We document the international transmission of geopolitical uncertainty through trade linkages. Export links as well as import links serve as important nexus of transmission of geopolitical risks across borders. Hedging strategies involving foreign-exchanges derivatives do not seem to insulate firms again geopolitical risks. With the recent movements of localization and reshuffling of the global value chain, our results suggest a significant impact of geopolitical risks in Korea on the construction of the global value chain.

• Journal of the Korean Society of Physical Medicine
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• v.2 no.1
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• pp.31-39
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• 2007

Purpose : The main purpose of this study was to investigate the influence of lower extremity strengthening on balance ability of knee osteoarthritis. Methods : The walking exercise group with modality treatment and strengthening exercise group with modality treatment. The walking exercise and strengthening for 40 minutes per day and three times a week during 6 weeks period. Short Form McGill Pain Questionnaire(SFMPQ) was used to measure patient's pain level. Patient Specific Functional Scale(PSFS) was used to measure patient's functional disability level. BPM was used to measure sway area. Global Perceived Effect Scale(GPES) was used to measure recovery or worse of patient's condition. Results : 1. SFMPQ was strengthening exercise group showed significantly decreased more than walking exercise group(p<.05). 2. PSFS was strengthening exercise group showed significantly increased more than walking exercise group(p<.05). 3. Sway area was strengthening exercise group showed significantly limited area more than walking exercise group(p<.05). 4. GPES was strengthening exercise group showed significantly increased more than walking exercise group(p<.05). Conclusion : This study will be used as exercise method of patient with osteoarhtritis.

• Journal of the Korean Society of Physical Medicine
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• v.2 no.1
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• pp.21-30
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• 2007

Purpose : this study was to investigate the influence on lower extremity pattern of PNF to muscle questionnaire ability of patients with knee OA. Methods : The subjects were consisted of 60 women patients with knee OA. And all subjects were randomly devide to two group which was modality group and PNF group. Each group had a treatment for 30 minutes per day and three times a week during 8 weeks period. VAS was used to measure pain, patient specific functional scale(PSFS) was used to measure patient's functional disability level, global perceived effect scale(GPES) was used to measure recovery or worse of patient's condition, muscle assessment questionnaire (MAQ) was used to measure patient's pain level. Results : 1. VAS was showed that PNF group had more significantly decreased than modality group(p<.05). 2. PSFS was showed that PNF group had more significantly increased than modality group(p<.05). 3. GPES was showed that PNF group had more significantly decreased than modality group(p<.05). 4. MAQ was showed that PNF group had more significantly decreased than modality group(p<.05). Conclusion : There are strong significant between PNF group and modality group.

• PNF and Movement
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• v.4 no.1
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• pp.19-25
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• 2006

Purpose : The main purpose of this study was to investigate the influence of walking exercise on balance ability of knee osteoarthritis. The subject were consisted of 30 women patients with knee osteoarthritis. Method : The walking exercise group with modality treatment. The walking exercise for 40 minutes per day and three times a week during 6 weeks period. Short Form McGill Pain Questionnaire(SFMPQ) was used to measure patient's pain level. Patient Specific Functional Scale(PSFS) was used to measure patient's functional disability level. BPM was used to measure sway area. Global Perceived Effect Scale(GPES) was used to measure recovery or worse of patient's condition. Results : 1. SFMPQ was walking exercise showed significantly decreased more than before treatment (p<.05). 2. PSFS was walking exercise showed significantly increased more than before treatment (p<.05). 3. Sway area was walking exercise showed significantly limited area more than before treatment (p<.05). 4. GPES was walking exercise showed significantly increased more than before treatment(p<.05) Conclusion : This study will be used as exercise method of patient with osteoarhtritis.

• Proceedings of the Korean Statistical Society Conference
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• 2002.05a
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• pp.79-83
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• 2002

Since its introduction in 1995 by Schena et al. cDNA microarrays have been established as a potential tool for high-throughput analysis which allows the global monitoring of expression levels for thousands of genes simultaneously. One of the characteristics of the cDNA microarray data is that there is inherent noise even after the removal of systematic effects in the experiment. Therefore, replication is crucial to the microarray experiment. The assessment of reproducibility among replicates, however, has drawn little attention. Reproducibility may be assessed with several different endpoints along the process of data reduction of the microarray data. We define the reproducibility to be the degree with which replicate arrays duplicate each other. The aim of this note is to develop a novel measure of reproducibility among replicates in the cDNA microarray experiment based on the unprocessed data. Suppose we have p genes and n replicates in a microarray experiment. We first develop a measure of reproducibility between two replicates and generalize this concept for a measure of reproducibility of one replicate against the remaining n-1 replicates. We used the rank of the outcome variable and employed the concept of a measure of tracking in the blood pressure literature. We applied the reproducibility measure to two sets of microarray experiments in which one experiment was performed in a more homogeneous environment, resulting in validation of this novel method. The operational interpretation of this measure is clearer than Pearson's correlation coefficient which might be used as a crude measure of reproducibility of two replicates.

• KIEAE Journal
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• v.14 no.2
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• pp.3-10
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• 2014

Impact by estimation error of hourly horizontal global solar radiation in a weather file on building energy performance was investigated in this study. There are a number of weather parameters in a given weather file, such as dry-bulb, wet-bulb, dew-point temperatures; wind speed and direction; station pressure; and solar radiation. Most of them except for solar radiation can be easily obtained from weather stations located on the sites worldwide. However, most weather stations, also including the ones in South Korea, do not measure solar radiation because the measuring equipment for solar radiation is expensive and difficult to maintain. For this reason, many researchers have studied solar radiation estimation models and suggested to apply them to predict solar radiation for different weather stations in South Korea, where the solar radiation is not measured. However, only a few studies have been conducted to identify the impact caused by estimation errors of various solar radiation models on building energy performance analysis. Therefore, four different weather files using different horizontal global solar radiation data, one using measured global solar radiation, and the other three using estimated global solar radiation models, which are Cloud-cover Radiation Model (CRM), Zhang and Huang Model (ZHM), and Meteorological Radiation Model (MRM) were packed into TRY formatted weather files in this study. These were then used for office building energy simulations to compare their energy consumptions, and the results showed that there were differences in the energy consumptions due to these four different solar radiation data. Additionally, it was found that using hourly solar radiation from the estimation models, which had a similar hourly tendency with the hourly measured solar radiation, was the most important key for precise building energy simulation analysis rather than using the solar models that had the best of the monthly or yearly statistical indices.

• Structural Engineering and Mechanics
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• v.13 no.4
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• pp.369-385
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• 2002

Ductility capacity is comprehensively studied for steel moment-resisting frames. Local, story and global ductility are being considered. An appropriate measure of global ductility is suggested. A time domain nonlinear seismic response algorithm is used to evaluate several definitions of ductility. It is observed that for one-story structures, resembling a single degree of freedom (SDOF) system, all definitions of global ductility seem to give reasonable values. However, for complex structures it may give unreasonable values. It indicates that using SDOF systems to estimate the ductility capacity may be a very crude approximation. For multi degree of freedom (MDOF) systems some definitions may not be appropriate, even though they are used in the profession. Results also indicate that the structural global ductility of 4, commonly used for moment-resisting steel frames, cannot be justified based on this study. The ductility of MDOF structural systems and the corresponding equivalent SDOF systems is studied. The global ductility values are very different for the two representations. The ductility reduction factor $F_{\mu}$ is also estimated. For a given frame, the values of the $F_{\mu}$ parameter significantly vary from one earthquake to another, even though the maximum deformation in terms of the interstory displacement is roughly the same for all earthquakes. This is because the $F_{\mu}$ values depend on the amount of dissipated energy, which in turn depends on the plastic mechanism, formed in the frames as well as on the loading, unloading and reloading process at plastic hinges. Based on the results of this study, the Newmark and Hall procedure to relate the ductility reduction factor and the ductility parameter cannot be justified. The reason for this is that SDOF systems were used to model real frames in these studies. Higher mode effects were neglected and energy dissipation was not explicitly considered. In addition, it is not possible to observe the formation of a collapse mechanism in the equivalent SDOF systems. Therefore, the ductility parameter and the force reduction factor should be estimated by using the MDOF representation.