• Asian Pacific Journal of Cancer Prevention
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• v.13 no.1
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• pp.305-308
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• 2012

Objective: To assess the health and economic burden of human papillomavirus (HPV)-related diseases (cervical cancer, cervical intraepithelial neoplasia (CIN) 1/2/3, and genital warts) in Singapore over a period of 25 years beginning in 2008. Methods: Incidence-based modeling was used to estimate the incidence cases and associated economic burden, with the assumption that age-stratified incidence rates will remain the same throughout the period of 25 years. The incidence rates in 2008 were projected based on data obtained from the National Cancer Registry for cervical cancer, and from a combination of published data and hospital registry review for CIN1/2/3 and genital warts. The population growth rate was factored into the projection of incidence cases over time. Direct cost data per cervical cancer and per CIN1/2/3 case were obtained from the financial database of large local hospitals while cost data for genital warts were obtained from the National Skin Center; these costs were multiplied by the number of incidence cases to produce an aggregate estimate of the economic burden over the 25-year period (in 2008 Singapore dollars) using a 3% discount rate. Results: The total number of incidence cases of HPV-disease over 25 years beginning in 2008 was estimated to be 60,183, including 8,078 for cervical cancer, 11,685 for CIN 2/3, 8,849 for CIN1, and 31,572 for genital warts. The estimated total direct cost was 83.2 million Singapore Dollars over 25 years: 57.6 million attributable to cervical cancer, 13.0 million to CIN2/3, 6.83 million to CIN1, and 5.70 million to genital warts. Conclusion: HPV-related diseases are expected to impose significant health and economic burden on the Singapore healthcare resources in the next 25 years.

• Journal of Korean Academy of Nursing
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• v.50 no.3
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• pp.313-332
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• 2020

Purpose: This year 2020 marks the 50th anniversary of the founding of the Korean Society of Nursing Science (KSNS). This study was aimed to explore development of caring and describe the 50 years of history of KSNS within the sociocultural context of Korea regarding academic footsteps, meanings, and implications for the future. Methods: This study used a historical research methodology using a literature review and bibliometric analysis. Relevant literature was reviewed and the published abstracts in the Journal of Korean Academy of Nursing (JKAN) were analyzed using VOSviewer. Results: Birth control and family planning in the 1970s was the main research topic. In the 1980s, the development of nursing concepts, theories, and philosophies was the mission of KSNS to extend the disciplinary boundary. In the 1990s, the progress of KSNS to become one of the woman-dominant healthcare professionals was the mission in the given period. Expanding the frontiers of KSNS to the extent of global standards was the undertaking of the nursing scholars in the 2000s. Lastly, in the 2010s, the quality and quantity improvement of KSNS and JKAN is expected to make our future even prosperous. The map visualization of the 50 years of research accumulation showed the comparable opposition of quantitative vs. qualitative research methodologies, equation modeling, and instrument development. Conclusion: These clusters of research demonstrates the efforts to make nursing evidence by Korean nursing scholars for the last five decades. The growth in the slope of KSNS and outcomes of JKAN are to carry on to an unimaginable extent in the future.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7685-7692
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• 2013

Background: Management of hypertension and diabetes in cancer survivors is an important issue; however, not much is known about the level of management of such chronic disease in Korea. This study therefore assessed the prevalence, awareness, control, and treatment of hypertension and diabetes in Korean cancer survivors compared to non-cancer survivors. Materials and Methods: A cross-sectional design was employed, wherein data were obtained from standardized questionnaires completed by 943 cancer survivors and 41,233 non-cancer survivors who participated in the Fourth and Fifth Korea National Health and Nutrition Examination Surveys (2007-2011). We calculated adjusted proportions for prevalence and management of hypertension and diabetes in non-cancer survivors and cancer survivors. We also assessed the associated factors with prevalence and management of cancer survivors. Results: Cancer survivors are more likely than the general population to have higher prevalence, awareness, treatment, and control of hypertension. However, diabetic management was not significantly higher in cancer survivors than in non-cancer survivors, despite their having a higher prevalence. Several factors, such as, age, drinking, years since cancer diagnosis, self-perceived health status, and specific cancer types were found to affect to management of hypertension and diabetes. Conclusions: These data suggest that cancer survivors appear to be better than non-cancer survivors at management of hypertension, but not diabetes. There is a need for healthcare providers to recognize the importance of long-term chronic disease management for cancer survivors and for the care model to be shared between primary care physicians and oncologists.

• The Korean Journal of Physiology and Pharmacology
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• v.13 no.1
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• pp.23-26
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• 2009

During operations, neurosurgeons usually perform multiple temporary occlusions of parental artery, possibly resulting in the neuronal damage. It is generally thought that neuronal damage by cerebral ischemia is associated with extracellular concentrations of the excitatory amino acids. In this study, we measured the dynamics of extracellular glutamate release in 11 vessel occlusion(VO) model to compare between single occlusion and repeated transient occlusions within short interval. Changes in cerebral blood flow were monitored by laser-Doppler flowmetry simultaneously with cortical glutamate level measured by amperometric biosensor. From real time monitoring of glutamate release in 11 VO model, the change of extracellular glutamate level in repeated transient occlusion group was smaller than that of single occlusion group, and the onset time of glutamate release in the second ischemic episode of repeated occlusion group was delayed compared to the first ischemic episode which was similar to that of single 10 min ischemic episode. These results suggested that repeated transient occlusion induces less glutamate release from neuronal cell than single occlusion, and the delayed onset time of glutamate release is attributed to endogeneous protective mechanism of ischemic tolerance.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.05a
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• pp.600-602
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• 2015

WHO(World Health Organization) as specified due to the global epidemic of obesity in the nation and the social costs associated with health increase. If treating diseases of the existing research targets the medical field with increasing interest in the welfare and well-being sector due to the improvement in earnings, and gradually change to advance the prevention and management. In this paper, we consider these social changes, we propose a personalized recommendation system fitness. This makes it possible that the recommendation is effective to the movement by the movement mechanism by which user. Mobile sensor is overcome by software and having hardware limitations for this purpose, proposes an optimized sensor control mechanism.

• YAKHAK HOEJI
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• v.56 no.3
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• pp.204-209
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• 2012

The purpose of this study was to construct database for a drug safety information website to serve as an access point of up-to-date resources for a wide variety of drug-safety information helping patients and healthcare professionals make well-informed decisions about medication use. All the contents developed were confirmed by the council of advisors who were the experts in drug safety. The detailed contents of database on frequently prescribed drug including 9 NSAIDs, 19 antibiotics, 24 cardiovascular, 21 metabolic, 14 respiratory, 20 digestive, 22 hormonal, 10 genitourinary, 10 anti-allergic, 27 antifungal/antiviral, and 71 neuropsychiatric agents were developed based on the approved drug labeling of the Korean FDA. A separately searchable database of drug-specific safety information for patients and health professionals was constructed for users in need of different depth of knowledge on using medications safely. The safety information on highly prevalent chronic diseases and drug classes was also developed. Finally the most recent global drug safety news was provided. The consumer directed information was developed in layman's terms as means of proving user-friendly information. The creation of this type of website is part of the Korean FDA's ongoing initiative to address and promote the safe use of medications for the public.

• Journal of Internet Computing and Services
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• v.13 no.5
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• pp.1-8
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• 2012

In this paper, we propose a new clustering combination based on numerical data driven for rule generation mechanism. In large and complicated space, a clustering method can obtain limited performance results. To overcome the single clustering method problem, hybrid combined methods can solve problem to divided simple cluster estimation. Fundamental structure of the proposed method is combined by mountain clustering and modified Chen clustering to extract detail cluster information in complicated data distribution of non-parametric space. It has automatic rule generation ability with advanced density based operation when intelligent systems including neural networks and fuzzy inference systems can be generated by clustering results. Also, results of the mechanism will be served to information of decision support system to infer the useful knowledge. It can extend to healthcare and medical decision support system to help experts or specialists. We show and explain the usefulness of the proposed method using simulation and results.

• The Korean Journal of Food And Nutrition
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• v.25 no.1
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• pp.156-162
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• 2012

The purpose of this study was to investigate the effect and correlation of anthropometric data, eating behaviors, and nutrient intake on the bone mineral density(BMD) of female college students. 349 female college students were surveyed and their age, height, and weight were an average of 20.5 years, 163.2 cm and 54.0 kg, respectively. Their average BMI was 20.2, with 66% falling in the normal range, 21.8% classified as underweight, 8.0% as overweight, and obese individuals comprised 3.4% of the sample by BMI classification. Calcaneal BMD was measured and the average T-score was 0.117. The results of BMD measurements were normal in 268 people(76.8%), osteopenia was found in 71 individuals(20.3%), and osteoporosis in 10(2.9%), respectively. There was a significant difference in bone mineral density according to height(p<0.05) and BMI (p<0.01). There were significant differences between BMD and eating behavior, regularity of eating behaviors(p<0.05), instant food intake(p<0.05), eating out(p<0.05) and nutritional supplement intake(p<0.05). In addition, normal the group with normal BMD had a more desirable eating behavior compared to the osteopenia and osteoporosis afflicted groups. BMD had a significant difference according to the nutrient intake of calcium(p<0.05), vitamin A(p<0.05), and vitamin C(p<0.05). In conclusion, BMD showed a good correlation with height(p<0.01), BMI(p<0.01), body composition including total body water(p<0.05), FFM(p<0.05), body protein(p<0.05) and intake of calcium(p<0.05), iron(p<0.05), vitamin A(p<0.05), and vitamin C(p<0.05). Therefore, an education plan and training on balanced diets proper body weight control, and desirable eating behaviors for female college students will be needed.

• Journal of Science and Technology Studies
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• v.13 no.1
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• pp.77-109
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• 2013

The global diffusion of Evidence-Based Medicine (EBM) is changing the landscape of medicine and the healthcare system. STS scholars have shown how EBM works when put into practice. In continuing to add to the literature of previous scholars, this paper traces the historical process and debate over Prostate-Specific Antigen (PSA) testing as an early screening test for prostate cancer in the U.S. This study will reveal that both pros and cons of the testing using EBM as a crucial resources of the debate, and in the process both 'flexibly' interpret and mobilize the hierarchy of scientific evidence for EBM despite the fact the hierarchy is imagined to being scientific criteria that is rigid. Furthermore, this paper will argue that this phenomenon, for which EBM currently seems to support the cons side of PSA screening, was constructed in the context of appraisal of the value 'quality of life' in the EBM system. This case study proposes that those who study the debate of medical technology in the EBM era should contextualize and analyze EBM as part of this debate rather than simply taking EBM for granted.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.559-566
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• 2018

Higher education has become a global phenomenon. Although existing research on the effects of education level have been carried out, most studies were conducted before the year 2000 in a western context. In addition, the research sample was collected mainly from the manufacturing and police sectors. Furthermore, previous studies did not consider various moderating variables. Therefore, this study investigated the direct effect of education level on job satisfaction and the moderating effect of the job position between them. To test the hypotheses, a cross sectional research design with data from a sample of 377 full-time nurses, medical technicians, and administrative staff in one hospital located in the Northern part of Kyunggi province was used. The results showed that the education level was positively related to job satisfaction and job position alleviated the positive relationship between the education level and job satisfaction.