• Title/Summary/Keyword: Giorgi

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Pharmacokinetics of oxytetracycline in hybrid catfish (Clarias macrocephalus x C. gariepinus) after intravascular and oral administrations

  • Amnart Poapolathep;Kednapat Sriphairoj;Sittichai Hatachote;Kannika Wongpanit;Duangkamol Saensawath;Narumol Klangkaew;Napasorn Phaochoosak;Mario Giorgi;Saranya Poapolathep
    • Journal of Veterinary Science
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    • v.25 no.4
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    • pp.58.1-58.8
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    • 2024
  • Importance: Over the past decade, catfish farming has increased in Southeast Asia. However, there has been no existing for pharmacokinetic data in the hybrid catfish (Clarias macrocephalus x C. gariepinus). Objective: This study was designed to evaluate the pharmacokinetic characteristics of oxytetracycline (OTC) in the hybrid catfish, following single intravascular (IV) or oral (PO) administration at a single dosage of 50 mg/kg body weight (BW). Methods: In total, 140 catfish (each about 100-120 g BW) were divided into two groups (n = 70). Blood samples (0.6-0.8 mL) were collected from ventral caudal vein at pre-assigned times up to 144 h (sparse samples design). OTC plasma concentrations were analyzed using high-performance liquid chromatography-photodiode array detector. Results: The pharmacokinetic parameter of OTC was evaluated using a non-compartment model. OTC plasma concentrations were detectable for up to 144 and 120 h after IV and PO, respectively. The elimination half-life value of OTC was long with slow clearance after IV administration in hybrid catfish. The average maximum concentration value of OTC was 2.72 ㎍/mL with a time at the maximum concentration of 8 h. The absolute PO bioavailability was low (2.47%). Conclusions and Relevance: These results showed that PO administration of OTC at a dosage of 50 mg/kg BW was unlikely to be effective for clinical use in catfish. The pharmacodynamic properties and clinical efficacy of OTC after multiple medicated feed are warranted.

Influence of Sugar Cane Diets and a High Fibre Commercial Diet on Growth and Carcass Performance in Local Caribbean Pigs

  • Xande, X.;Despois, E.;Giorgi, M.;Gourdinegi, J.L.;Archimedee, H.;Renaudeau, D.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.1
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    • pp.90-98
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    • 2009
  • The aim of this study was to evaluate the effect of a milling by-product diet and two sugar cane diets on the local Creole pig breed (CR). A total of 48 CR pigs (24 females and 24 castrated males) were randomly assigned to four different groups of 12 animals. Pigs were allotted to one of 4 dietary treatments: fed with a control soya-bean meal-corn diet containing 19.1% crude protein (CP) and 15.4 MJ DE/kg (diet 1), with an experimental milling by-product diet (soya-bean meal and wheat by-products) containing 19.4% CP and 13.0 MJ DE/kg (diet 2), with ground cane stalks (GCS) or with fresh sugar cane juice (SCJ). Both GCS and SCJ were supplemented with soya-bean meal complement (400 g/d of a 48.7% CP and 16.1 MJ DE/kg diet) in order to obtain diets 3 and 4, respectively. Pigs were fed close to ad libitum level and had free access to water. All the pigs were slaughtered at 65 kg BW. Between 30 and 65 kg BW, growth performance was significantly (p<0.001) affected by dietary treatments: average daily BW gain was 657, 530, 546 and 200 g/d for diets 1, 2, 4, and 3, respectively. Average daily DM intake was 1.8, 1.9, 2.5 and 1.4 kg/d for diets 1, 2, 4, and 3, respectively. Fat cuts (backfat+leaf fat) and backfat thickness were significantly lower on diet 3 than for other treatments (127 vs. 192, 166 g/kg of left half-carcass weight and 24.6 vs. 39.0, 35.3 mm for diet 3 vs. diets 1 and 4, and diet 2, respectively; p<0.001). The dressing weight was significantly lower on diets 2 (82.7 vs. 84.0%; p<0.001). The entire empty digestive tract (DT) weight was higher on diet 2 (73.1 vs. 66.7 g/kg empty BW). However, stomach and large intestine were more developed on diet 3: 12.8 vs. 9.3 g/100 g empty DT (p<0.001) and 26.4 vs. 23.8 g/100 g empty DT (p<0.05), respectively. In conclusion, this study suggests the CR pig has the ability to reach rather good growth and carcass performance with a well-formulated sugar cane meal and/or with a milling by-product diet refined according to its low requirements.

The Hope of the Stroke Patients (뇌졸중환자의 희망)

  • 김이순
    • Journal of Korean Academy of Nursing
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    • v.27 no.1
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    • pp.212-227
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    • 1997
  • Cerebrovascular diseases in Korea is an important health problem since mortality and mobidity have been increased rapidly. It marked the 2nd cause of specific death rates in 1993. The stroke causes physical function disorder due to hemiparalysis and emotional disorder, and stroke patients experience helplessness, powerlessness. sense of alienation and loss of hope. These feelings make the rehabilitation difficult because they lose the will of life. The subjects of the study were seven citizens who live in Pusan, are over 50 years old and belong to low income-level. The data were collected from Jan. to Sep. 1995. The researcher as a caregiver and volunteer made confidence of them and asked for their agreement on the purpose of the study. The subjects expressed their experience as openheartedly as possible. The analysis of the data was made through the phenomenological analytic method suggested by Giorgi, which is as follows ; as an unit of description which include the subject' expressions and the researcher's observation, it is examined the theme that express the hope experience with the subject's language(underlining), and the focal meanings are identified. The focal meaning is the crystalization of the theme, which is written in the language of the researcher. After intergrating the focal meaning and make the situated structural description as the meaning of the hope experience identified on each subject's point. After intergrating the situated structural description and make the general structural description as the meaning of the hope experience identified on total subject's point then the systemizing of the structure of the hope experienced phenomena and the flowing of the conciousness was researched. The conclusions of this study was as follows : The ten sources of hope which the subjects experienced were sorted as under 〈mutual relations to others : spouse, children, relatives, fellow believer. health professioner. associate patient group〉, 〈spiritual dependence〉. 〈recovery of physical function〉. 〈rumination of the past life〉, 〈expectation of the future〉. 〈economic power〉, 〈belief〉, 〈ability〉. 〈spontaneous participation〉 and 〈recovery of roles〉. Their hope was spoken out by the following two kinds of linguistics. First. the hope was expressed in the affirmative expression as follows : 〈 to be dependable〉, 〈to make efforts〉, 〈to keep under control〉, 〈to desire〉, 〈to be pleasant〉, 〈to be peaceful〉, 〈to be grateful〉, 〈to give help〉, 〈self-confidence. Courage〉, 〈to be happy〉, 〈to satisfy oneself〉, 〈to share with others〉, 〈to understand〉 and 〈to be affected, be impressed〉 Second, the hope was expressed in the negative on pression as under : 〈to be distressed〉, 〈to be uneasy〉, 〈to be sorry, be unsatisfied〉 〈despair〉, 〈to abandon〉, 〈to be fearful〉, 〈to suffer〉, 〈to bear a burden〉 〈to be confused〉, 〈to be solitary〉, 〈chest trouble〉, 〈to feel heavy〉 〈grief〉, 〈to be daunted〉, 〈to get angry〉, 〈to be uncomfortable〉, 〈to have something regretable〉 and 〈to feel guilty〉. And their hope was expressed by the following four behavioral expressions : 〈physical sphere〉, 〈psychological sphere〉, 〈social support sphere〉 and 〈spiritual sphere〉. The reaction patterns of their hope experience appeared in the following 4 coping method : 〈conquest type〉, 〈dependence type〉, 〈adaptation type〉 and 〈fate type〉. Finally, in the hope structure the sense of certainty don't always coexict with the sense of uncertainty, When the stroke patients try to search for the best quality of life, the senses of certainty and uncertainty make a continual cyclic system in the hope structure.

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A Phenomenologic Study on the Married Nurse's Experience of Child Rearing (기혼간호사의 육아경험에 관한 현상학적 연구)

  • Cho, Cheong-Ho
    • Women's Health Nursing
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    • v.2 no.2
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    • pp.182-201
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    • 1996
  • The purpose of this study is to examine a married nurse's experience of child rearing through being applied to phenomenological research method. By exchanging their experiences, helping and understanding one another, married nurses can work with delight considering their own present job as their lifelong job. In addition this study can help single nurses overcome the female crises such as marriage, childbirth, and child rearing they will experience in the future. The subjects of this research was 26 married nurses who work for a university hospital in affiliation in Seoul and have children. The period of materials collection was from Feb. 1st to Mar. 3, 1995. The method of materials collection was primarily to write down a questionary with openhearted contents. In collecting it, the respondents were allowed to say at their pleasure through further interview. The materials were analyzed by Giorgi's phenomenological analysis method. The findings of this study are as follows ; 1) The responses of married nurses' experience of child rearing-[pleasure] [family solidarity] [maternal-infant attachment] [understanding] [toilsome]-were induced. That is, at once affirmative experience and hard experience coexisted. 2) The method of married nurses' child rearing-[rearing politely] [raising understanding] [having the sense of family community] [rearing with praying the heart] [careless]-were induced. 3) The support system of married nurses' child rearing-[having help family] [having help from others]-were induced. According to the above findings, the married nursed showed affirmative responses about their experience of child rearing, but at the same time they expressed painful when stayed apart from their children on account of their job or when their children were sick. In the method of child rearing, they tried to grow their children polite because there was much time for them to stay apart from their children. And they tried to give a better explanation in order that their children can have an independence spirit. They tended to compensate through frequent physical touch with their children. As the support system of married nurses' child rearing, they asked their parents or their parents-in-law to take care of their children, hired a nursery governess in their houses, or used a children's home, if they can't afford to. That is, the only one who has a firm sense of her profession, tries to inspire her accomplishment, and is receiving her husband' love and understanding is considered to perform two things simultaneously with harmony, having an recognition of lifelong job. Suggestions 1. The method to solve mental troubles on child rearing should be groped. 2. Their economical burden should be reduced by establishing children's home in their working places, and the increase of maternal-infant interaction should be contrived. 3. The chance of education should be offered in order that married nurses themselves might inspire self-conceit and professionalism on clinical nursing. 4. The familiar mood should be created through planning the programs to be accompanied with children as an annual event in hospital. 5. The part-time nurse system should be suggested to utilize. 6. The system of circulation working should be converted into the system of fixing working according to the characteristic of each department. 7. Programs for special activities such as learning foreign languages and computer should be supported positively.

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A Phenomenological Study on Experiences as a Dental Intermediary Manager (치과 중간관리자의 근무경험에 대한 현상학적 연구)

  • Moon, Hak-Jin;Lim, Soon-Ryun
    • Journal of dental hygiene science
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    • v.16 no.4
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    • pp.263-271
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    • 2016
  • This study aimed at comprehending the duty, role, and difficulty of intermediary manager through in-depth investigation of dental hygienist intermediary managers experienced over 10 years working in a dental clinic. In-depth interviews were conducted with 10 dental intermediary managers and Giorgi's analysis method was used to analyze the data. Findings revealed that the work experience of the dental hygienist intermediary managers appeared in the range of "becoming an intermediary manager through various processes", "various duties that they experience as an intermediary manager", "difficulty as an intermediary manager", "ability that they perceive as necessary for being a dental intermediary manager", and "worthiness they feel as the intermediary manager". The dental intermediary managers complained of difficulties at work, and appeared to perform various tasks such as human resource management, clinic management support, and patient's management. Accordingly, the researcher considers that research on dental intermediary managers' capacity development necessary.

The Experiences of Trial Alternative Therapies for Cancer Patients (암환자의 대체요법 시행경험)

  • Go, Dock-Soon;Chung, Yeon-Kang
    • Journal of Home Health Care Nursing
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    • v.8 no.2
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    • pp.109-120
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    • 2001
  • This study has been done in order to help the people understand the cancer patients and provide the basic materials for the care of cancer patients by deeply understanding the living experience of the practice of alternative therapy for cancer patients. Data were collected with several in depth interviews and observations. Collected datas were analyzed by using phenomenological method of study by Giorgi (1970). The trial experience of alternative therapy for cancer patients has been classified into the one of having concerns, following, being infatuated, and coming out by pushing, and the experience of having concerns appeared as the meaning of the limit of modern medicine, despair, loneliness. hope, emotional support. dissolution of the feeling of uneasiness. the feeling of burden of the medical expense, self-treating, the subject of treatment. and indifference while the experience of following appeared as the meaning of blind following, temptation, going outside to look for something, wandering. following unconditionally, advise of the professionals, mistaken belief. self-abandonment, powerlessness. disconnection of dialogue with the medical staff. elevation of immunity, strengthening the physical power, absence of the source of examined information, clinging, self-responsibility. the experience of being infatuated appeared as the meaning of thorough trial. affirmative experience. devotion. diverse efforts, faithful trial. affirmative self-suggestion. change of the style of life. the feeling of burden of expense, being envious, bitter feeling toward the family, considering family, family discords, and difficulty of enforcement. The experience of coming out by pushing appeared as the meaning of waiting. self-reflection. maintaining the distance. cutting attachment, throwing the greed away, coming out by pushing. being thoughtful. accepting disease. individual difference of physical quality, and ambivalence. But they return to the experience of being concerned all over again in case of recurrence or metastasis of the disease even though they come out of such stage, and they always have ambivalence even in the condition with no recurrence and metastasis. In conclusion, the trial of alternative therapy for cancer patients could be explained as the adaptive behavior to the disease which is difficult to be cured. the cancer. The cancer patients are exposed to the side effects and harm without the examined information resources. Therefore the nurse should well aware of the alternative therapy and be able to do the appropriative management through the open communication with the patients who are under the trial of alternative therapy.

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The Phenomenological Study on the Individuation Process of the Middle Aged Women Experienced Severe Depression (우울증을 경험한 중년여성의 개성화과정에 관한 현상학 연구)

  • Park, Sook-Kyung;Shin, Dong-Yeol
    • Industry Promotion Research
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    • v.5 no.2
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    • pp.51-58
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    • 2020
  • Middle-aged women who have experienced the depression have been in pain for a long time. Depression in middle-aged women, which is rapidly increasing from their forties, has a problem that do not decrease in spite of various treatment methods. If the essential cause of depression in middle-aged women is due to the inability to detect the meaning of life because of the lack of the perception about the identity resulting from self-loss, a more qualitative research for a fundamental treatment method is required. The purpose of this study is to find out the essence and meaning of the experience of depression in middle-aged women and to help them to find their own selves through the process of individualization and to recover the whole health as well as to live as a self-transcendent being. Three Christian middle-aged women falling on critical and serious condition by BDI diagnosis were selected for the study. In-depth counseling and interviews were held from January to August 2018. In-depth counseling has provided detailed statements about the process of individualization of middle-aged women who have experienced depression, which applied 5 stages of Giorgi's Phenomenological Research Methodology. As a result, 261 semantic units and 11 sub-components were derived and structured by dividing them into two themes: depression experience and the process of individualization process, which are the subject group. This study has its significance in realizing essential meaning of pain by middle-aged women who experience depression and fundamentally preparing an opportunity to be cured through the process of individualization, as well as contributing for such middle-aged women to have abundant living by suggesting preventive measures to general middle-aged women who prepare for their old age.

The Cadaver experience of the nursing students

  • Kim, Jung-ae;Eui-Young, Cho
    • International Journal of Advanced Culture Technology
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    • v.5 no.3
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    • pp.11-23
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    • 2017
  • Anatomy is one of the basic subjects of the nursing course, which is included in the curriculum of the nursing. Anatomy is a basic course for understanding major in nursing and it is the first gateway to acquire expertise. It is mainly opened in nursing and first to second grades. Therefore, students who have advanced to the nursing department have great interest and expectation on the anatomy subjects. In general, nursing students are studying anatomy with theories and models, and some universities practice on tour after dissection of medical consortium for short time. This is called the Cadaver practice. This study was carried out to investigate the thoughts and experiences of bioethics through nursing students' Cadaver practice. The interview data were processed through the analysis and interpretation process using the phenomenological research method, Giorgi method. As a result, 48 semantic units were derived, and then they were divided into 10 subcomponents and divided into 6 categories. As a result of the analysis, the experience of nursing students' bioethics was tied to the topic of six questions. For example, 'what about the respect and responsibility of nursing students in Cadaver?', 'What about your experience with the Cadaver experiment and bioethics?', 'What was the academic achievement of the actual human body structure viewing experience with cadaver?', 'What was the connection with theory?', 'What was your intention to recommend to others?', 'What was your perception and interest in the Cadaver experiment?'. Analyzes were integrated into 10 structures; "Thank you for your donation", "want others to refuse donation", "Burden of practice", "Good opportunities for learning", "Understand better", "Should study harder", "Memory is better", "Compared to theory", "Good experience", "Want to rejoin". The general structural description of the participants' meanings is summarized as follows. Nursing college students who participated in the Cadaver had a gratitude for the donor, but they said they would like to talk to others about donating organs. Before they went to practice, they felt a lot of pressure on the dissection of the cadaver, but they went to the practice and thought that it was a good opportunity to learn by doing well. Specifically, they understood that they had better understanding than the theoretical lesson, and that they were more eager to study their major through practice. In other words, most of them were more memorable and they would like to participate again if the opportunity comes next time. The results of this study show that the practice of Cadaver in nursing college students is very positive in terms of educational effectiveness. However, in terms of bioethics, it can be seen that the education process is somewhat unsatisfactory. Therefore, the systematic bioethics education should be prepared before the practice in the nursing college students' Cadaver practice.

The Lived Experiences of Inpatients' Families in the Intensive Care Units (중환자실 입원환자 가족의 경험)

  • Hwang, Hye Nam;Kim, Kwuy Bun
    • Korean Journal of Adult Nursing
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    • v.12 no.2
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    • pp.175-183
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    • 2000
  • The study was done by applying a phenomenological study, which is qualitative research methods, in order to understand the meaning of the lived experiences, to confirm and describe the meaning structure, and to prepare nursing interventive strategies centering around the meanings of the inpatients' families in the intensive care units. In the study, the family members were the main important nursing providers for in the inpatients' who were admitted in the neurosurgical intensive care unit in K-university hospital and who agreed to participate in the study after being given on explanation about the purpose of the study. The data were collected from the seven participants who had feelings of trust and intimacy favorable toward the researcher as they were families of patients who had been cared for by the researcher in the ICU where the researcher has been assigned. The data were collected from April to October, 1999. The participants described their experiences as candidly as possible. The researcher described closely the lived experiences with their own words and the observations of the researcher. A tape recorder was used with the consent of the participants to prevent nursing information and communication. The analysis of the data was made through the phenomenological analytic method suggested by Giorgi; as an unit of description, which include the participants' expressions and the researcher's observations, the analysis was used based on the data described from the expressions of the participants and the details of observations of the researcher. The conclusions of the study were as follows : The meanings of the lived experience of the inpatients' families in the ICU was confirmed by indepth interviews and observations including these of the participatants : (1) Psychological impact: confusion, impatience, surprise, insensibility; (2) Physical suffering: fatigue, discomfort, indigestion; (3) Psychological suffering: heartbreaking emotion, anxiety, annoyance, fear, compassion, grief; (4) Economical suffering: economical difficulties; (5) Psychological disagreement: escape from reality, personnel avoidance, grudge, powerlessness, carefulness, transposition of life-tract, abandonment, role-crisis, hope, lack of understanding, regret, feeling of ambivalence(progressive process, medical personnel interest); (6) Psychological dependency; self-reliance group support, family support, religious support; (7) Psychological acceptance; acquaintance, gratitude, reassurance; The study will offer better understanding of experiences therefore, based on the experiences confirmed by the study, it may facilitate more appropriate nursing interventive strategies for health maintenance and to prevent occurrence of possible problems with the inpatients' families in the ICUs.

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Sexual Perception of Female College Students (여대생의 성(性)인식)

  • Kim, Kwuy-Bun;Oh, Hye-Kyung
    • Journal of East-West Nursing Research
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    • v.5 no.1
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    • pp.19-35
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    • 2000
  • This study confirms and describes the meaning of the true experience on sexual perception of female college students as it is. Thus this study, revealing the structure of the meaning, tried to use phenomenal study tool as qualitative research design in order to seek nursing intervention for them. The method of data collection of this study was achieved February, 2000$\sim$August, 2000 through systematic interview, participation and observation from a focus group. The number of each focus group was 3 to 4, and the study analyzed with Giorgi method after selecting total 3 groups with 10 to saturate data, considering of the closeness among group members. The results are as follow; 1) Feeling psychological uneasy : feeling special mood, mysterious thing, tense thing, curious thing, concealing thing 2) Being to someone : receiving unilaterally, giving ahead, attracting attention, being to, being selected unilaterally 3) Feeling like to do together : relying, contacting, being together 4) Accepting another one's self : understanding the partner, taking responsibility for each other, enduring, trusting each other 5) Trying to be best to the partner : physically being pure, mentally being pure, being only one person to the partner, being open to each other, feeling free 6) Harmonizing conditions with conditions : considering appearance, one's family, economic support and so on 7) Making a love without premise of marriage : making a difference between marriage and love 8) Being a difference between men and women : being a different position, being shameful (because of not having a boyfriend), indecent thing 9) Being for a new life : conceiving a new life 10) Being able to have body touch : being able to kiss, being able to sleep together, being able to touch body 11) Being able to make homosexual love : being able to do homosexual love From the above results, right sexual education should deliver the value of sex which exists for life. So we need to develop the Korean-typed sexual education, according to the social and cultural background and reasonable demand level of education subjects. Furthermore we should give systematically connected education through the development of sexual education program by a developmental stage on the sex with broad and dynamic features, revealing different shapes each period of life. Since the members' value by culture is very different, reasonable and healthy sexual education cannot be done through a education program from foreign cultures. Consequently, the development of the study and program on sexual perception of Korean female college students suitable for the Korean cultural situation will be done.

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