• Title/Summary/Keyword: Ginsenoside Composition

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Saponin and Ginsenoside Content in Korean Red Ginseng Products (고려홍삼 제품류의 사포닌 및 진세노사이드 함량)

  • 최강주;고성룡
    • Journal of Ginseng Research
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    • v.13 no.2
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    • pp.178-182
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    • 1989
  • Red ginseng products manufactured by the Korea Ginseng and Tobacco Corporation were analyzed to determine the crude saponin , total saponin and ginsenoside contentents by gravimetry, spertrometry and HPLC, respectively, to see if effective quality control of the components in the products can be achieved. Medicinal powders, powders, tablets and capsules which were made from ginseng powder showed similarity in saponin content, the ratio of PD to PT saponin, and the ginsenoside content and composition, while extract powder, extract, extract tea, extract pills and tea, which were made of ginseng extract, showed difference in saponin content, ratio of PD to PT saponin, and the content and composition of ginsengside. It is, accordingly, believed that ginseng products which are uniform in contents and saponin composition can be produced by carrying out strict quality control throughout the processes of making raw red ginseng into final products.

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Effects of Black Ginseng (9 Times-Steaming Ginseng) on Hypoglycemic Action and Changes in the Composition of Ginsenosides on the Steaming Process (흑삼(구증구포인삼)이 혈당 강하에 미치는 영향 및 증포별 ginsenoside 조성 변화)

  • Kim, Suong-Nuen;Kang, Shin-Jyung
    • Korean Journal of Food Science and Technology
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    • v.41 no.1
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    • pp.77-81
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    • 2009
  • This study examined the effects of black ginseng (9 times-steamed ginseng) on hypoglycemic action in streptozotocininduced diabetic rats as well as changes in ginsenoside composition by the steaming process. As the number of steaming cycles increased, the amounts of crude saponin and most ginsenoside contents decreased, while the amount of ginsenoside- Rg3 and the ratio of PD/PT (=[$Rb_1+Rb_2+Rc+Rd+Rg_3]/[Re+Rb_1+Rh_1]$) increased. This ginsenoside composition is a unique characteristic compared to other types of ginseng products. In order to investigate the hypoglycemic effect of the black ginseng extract, in vivo studies were performed in rats with streptozotocin-induced diabetes. The studies showed that the administration of the black ginseng extract decreased high blood glucose levels (more than 300 mg/dL) to a normal level (102 mg/dL). These results suggest that this black ginseng extract has a significant hypoglycemic effect and can be used as an anti-diabetic substance for dietary supplements or new drugs.

Analysis of Ginsenoside Composition of Ginseng Berry and Seed

  • Ko, Sung-Kwon;Bae, Hye-Min;Cho, Ok-Sun;Im, Byung-Ok;Chung, Sung-Hyun;Lee, Boo-Yong
    • Food Science and Biotechnology
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    • v.17 no.6
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    • pp.1379-1382
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    • 2008
  • This study was performed to provide basic information that can be used to differentiate Korean ginseng (Panax ginseng CA. Meyer) berry and seed from American ginseng (Panax quinquefolium L.) seed. Total ginsenoside contents of Korean ginseng berry, Korean ginseng seed, and American ginseng seed were 9.09, 3.30, and 4.06%, respectively. Total ginsenoside content of Korean ginseng berry was about 2.2 to 2.7 times higher than those of Korean ginseng seed and American ginseng seed. Particularly ginsenoside Re content of 4-year cultivated Korean ginseng berry (5.99%) was about 3.6 to 5.4 times higher than that of 4-year cultivated Korean ginseng seed (1.65%) and 4-year cultivated American ginseng seed (1.10%). The contents of total ginsenoside and ginsenoside Re of Korean ginseng berry were about 4.8 and 28 times higher, respectively, than those of 4-year cultivated Korean ginseng root. In general the contents of total ginsenoside and ginsenoside Re of Korean ginseng berry were significantly higher than those of Korean ginseng seed and American ginseng seed.

Effects of Root Diameter Within Different Root Parts on Ginsenoside Composition of Yunpoong Cultivar in Panax ginseng C. A. Meyer (인삼 연풍의 근 부위별 직경이 진세노사이드 함량에 미치는 영향)

  • Li, Xiangguo;Kang, Sun-Joo;Han, Jin-Soo;Kim, Jung-Sun;Choi, Jae-Eul
    • Korean Journal of Medicinal Crop Science
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    • v.17 no.6
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    • pp.452-457
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    • 2009
  • This study was carried out to investigate the correlation between root diameter and ginsenoside composition of Panax ginseng C. A. Meyer cultivar Yunpoong. Dry matter ratio of main root was a little higher than that of lateral root and fine root, and that was higher by the increase of root diameter in the same root parts. Total ginsenosides composition of main and lateral roots increased by the decrease of root diameter, especially in lateral root. Similar resulted in fine root, but there was no significant difference where root diameter was below 2.5 mm. Except for ginsenoside-$Rg_1$, other ginsenosides component, PDs, PTs and total ginsenosides had highly negative correlation with the root diameter within whole root, main root+lateral root and lateral root+fine root, while $Rg_1$ had positive correlation with the root diameter.

Ginsenoside profiles and related gene expression during foliation in Panax ginseng Meyer

  • Kim, Yu-Jin;Jeon, Ji-Na;Jang, Moon-Gi;Oh, Ji Yeon;Kwon, Woo-Saeng;Jung, Seok-Kyu;Yang, Deok-Chun
    • Journal of Ginseng Research
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    • v.38 no.1
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    • pp.66-72
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    • 2014
  • Panax ginseng is one of the most important medicinal plants in Asia. Triterpene saponins, known as ginsenosides, are the major pharmacological compounds in P. ginseng. The present study was conducted to evaluate the changes in ginsenoside composition according to the foliation stage of P. ginseng cultured in a hydroponic system. Among the three tested growth stages (closed, intermediate, and opened), the highest amount of total ginsenoside in the main and fine roots was in the intermediate stage. In the leaves, the highest amount of total ginsenoside was in the opened stage. The total ginsenoside content of the ginseng leaf was markedly increased in the transition from the closed to intermediate stage, and increased more slowly from the intermediate to opened leaf stage, suggesting active biosynthesis of ginsenosides in the leaf. Conversely, the total ginsenoside content of the main and fine roots decreased from the intermediate to opened leaf stage. This suggests movement of ginsenosides during foliation from the root to the leaf, or vice versa. The difference in the composition of ginsenosides between the leaf and root in each stage of foliation suggests that the ginsenoside profile is affected by foliation stage, and this profile differs in each organ of the plant. These results suggest that protopanaxadiol- and protopanaxatriol(PPT)-type ginsenosides are produced according to growth stage to meet different needs in the growth and defense of ginseng. The higher content of PPT-type ginsenosides in leaves could be related to the positive correlation between light and PPT-type ginsenosides.

Changes of Chemical Compositions and Ginsenoside Contents of Different Root Parts of Ginsengs with Processing Method (인삼의 가공방법에 따른 일반성분 및 Ginsenoside 함량 변화)

  • Choi, Jae-Eul;Nam, Ki-Yeul;Li, Xiangguo;Kim, Bok-Young;Cho, Hang-Sik;Hwang, Kuang-Bo
    • Korean Journal of Medicinal Crop Science
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    • v.18 no.2
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    • pp.118-125
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    • 2010
  • This study was carried out to determine changes in general chemical composition, free sugars, physicochemical properties of extract, and ginsenoside contents depending upon processing methods. Ginseng roots harvested from the same field were employed for the processing into white ginseng (WG), taegeuk ginseng (TG), red ginseng A (RGA, steamed one time), and red ginseng B (RGB, steamed three times). The fat content decreased by increasing duration of treatment and number of steaming treatment. On the other hand, there was no significant variation in contents of ash and carbohydrate depending on processing methods. Contents of sucrose and maltose was higher in Taegeuk and red ginseng than those of white ginseng. Steamed ginseng root (taegeuk and red ginseng root) showed higher amount of water extractable solid than the unsteamed white ginseng, but the variation of crude saponin content was not distinctive depending on processing methods. The contents of total ginsenosides increased by the order of white, taegeuk, red A, and red B root. In summary, chemical composition and total ginsenoside content were different according to part of root and processing methods, thus implies the importance of quality control as well as pharmacological activity of ginseng root.

Changes in ginsenoside composition of ginseng berry extracts after a microwave and vinegar process

  • Kim, Shin-Jung;Kim, Ju-Duck;Ko, Sung-Kwon
    • Journal of Ginseng Research
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    • v.37 no.3
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    • pp.269-272
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    • 2013
  • MGB-20 findings show that the ginseng berry extracts that had been processed with microwave and vinegar for 20 min peaked in the level of ginsenoside Rg2 (2.28%) and Rh1 (1.28%). MGB-1 peaked in the level of ginsenoside Rg3 (1.13%) in the ginseng berry extract processed with microwave and vinegar for 1 min.

Comparison of Ginsenoside Content According to Age and Diameter in Panax ginseng C. A. Meyer Cultivated by Direct Seeding (직파 4 ~ 6년생 인삼의 연근 및 직경에 따른 Ginsenoside 함량 비교)

  • Han, Jin Soo;Tak, Hyun Seong;Lee, Gang Seon;Kim, Jung Sun;Choi, Jae Eul
    • Korean Journal of Medicinal Crop Science
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    • v.21 no.3
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    • pp.184-190
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    • 2013
  • This study was carried out to investigate ginsenoside content in different root parts and the correlation between root diameter and ginsenoside composition of Panax ginseng C. A. Meyer cultivated by direct seeding. The unit contents of ginsenoside were 29.65, 28.76, 26.34 mg/g, respectively in 4, 5, 6 years old. However, the total contents of ginsenoside were 431.97, 606.56, 657.80 mg/root, respectively. Total ginsenoside content of fine root was higher than that of main root and lateral root. These tendencies were related to decrease by the increase of root diameter. When diameter of main root and lateral root were the same in different ages, the total ginsenoside content was higher in the order of 4 > 5 > 6 years old roots. Except for ginsenoside-Rg1, other ginsenosides components (PD/PT and total ginsenosides) had highly negative correlation with the root diameter within whole root, main root, lateral root and fine root, which indicated that ginsenoside content is correlated to root diameter. As results, it is suggested that ginsenoside content can be predicted.

Composition of Saponin and Free Sugar of Some White Ginsengs with Processing Conditions (가공방법에 따른 몇가지 백삼 제품의 사포닌 및 유리당 조성 변화)

  • Lee, Boo-Yong;Kim, Eun-Jeong;Park, Dong-Jun;Hong, Seok-In;Chun, Hyang-Sook
    • Korean Journal of Food Science and Technology
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    • v.28 no.5
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    • pp.922-927
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    • 1996
  • To analyse components of fresh ginseng and some white ginsengs with different processing conditions, approximate composition, extraction yield, total saponin content and composition and free sugar composition of fresh ginseng, white ginseng, Taeguksam A and Taeguksam B were examined. Yield of hot water extraction was two times higher than that of 80% methanol extraction. Hot water extraction yields of fresh ginseng, white ginseng, Taeguksam A and Taeguksam B were 56.4, 39.9, 42.9 and 46.6%, respectively, while the 80% methanol extraction yields ranged from 15.8% to 21.9%. Total saponin contents of the above were 2.40, 1.73, 1.45 and 1.79%, respectively, with hot water extraction and were 2.15, 2.99, 2.81 and 2.35%, respectively, with 80% methanol extraction. Ginsenoside compositions of the above varied with processing conditions and extraction solvents. Hot water and 80% methanol extracts of fresh and white ginseng composed of fructose, glucose, sucrose and maltose. Rhamnose was detected only in the extract of Taeguksam A and B.

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