• Journal of Ginseng Research
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• 제22권2호
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• pp.91-95
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• 1998

The distribution of phenolic components of Korean ginseng (Panax ginseng KG) and American ginseng (Panax quinquefolium, AG) were compared by thin-layer chromatography (TLC). Silica gel TLC gave 3~4 spots, while $NH_2$ HPTLC 5~6 spots, which were colored by both $FeCl_3$/$K_3Fe(CN)_6$ and Folin-Ciocalteu. The distribution of phenolic components was quite different between KG and AG. Especially, a polyphenol (m.w. 578), which had been isolated from KG by the author, was not found in AG. This result suggests that the polyphenol could be used as an index compound for the differentiation of KG from AG.

• Journal of Ginseng Research
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• 제1권1호
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• pp.29-32
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• 1976

숙신산 탈수소효소의 활동성은 홍삼의 초산에틸 추출액과 초산에틸 추출모액의 수용 성 추출액 분획들에 의하여 활성화되었으며, 홍삼의 에테르 추출액 분획을 제외한 모든 분획들에 의하여 활성화되었다. 다른 사람들이 알칼로이드류는 숙신산 탈수소효소의 활동성을 증진시킨다는 암시와는 반대로 저자들의 연구결과는 오히려 인삼의 알칼로이프들은 이 효소의 활동성에 대하여 방해효과를 가졌음을 알려주었다.

• Journal of Ginseng Research
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• 제7권1호
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• pp.1-12
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• 1983

This study was divised to observe the effects of ginseng on the body components of Sprague-Dowley Albino male rats by alternating the diet. Just weaned rats (130 heads, weighing(83 ${\pm}$ 4g) were fed with each stock diets supplemented with 0.5, 1.0 or 3.0% ginseng powder for 4 weeks or 8 weeks, and after that fed with stock diet only for 8 or 4 weeks. Compared with the each corresponding group which was fed with ginseng control diet, the protein, total lipid, total cholesterol and free cholesterol contains in serum, liver and aorta of them were determined. The results obtained was summarized as follows ; Protein and total lipid contents of the rat were decreased, caused by the alternating diets, but total cholesterol and free cholesterol contents were increased in the serum, protein and free cholesterol contents increased, conversely total lipid contents decreased in the liver, and in aorta total lipid and total cholesterol contents decreased, In the view of the above results, it can be seen that the alternating diet (stock diet after feeding with ginseng diet) has an influence on the body components of rat.

• Journal of Ginseng Research
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• 제20권1호
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• pp.1-6
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• 1996

Effects of Panax ginseng on allergic reactions were studied uslng various in vivo and in vitro experimental models such as 48-hr passive cutaneous anaphylaxis, mediators-induced skin reactions, histamine release from rat peritoneal mast cells, hexosaminidase release from RBL-2H3 cells, and lipoxygenase assay . In all of anti-allergic experiments we conducted, ginseng components (50% ethanol extract or ginseng total saponin or ginsenosides) extracted from Korean red ginseng, did not show significant anti-allergic actions. In 48-hr passive cutaneous anaphylaxis and mediators-induced skin reactions, 50% ethanol extract did not suppress hypersensitivity reactions. Total saponin, 50% ethanol extract, and 8 major ginsenosides did not show inhibitory effects on lipoxygeanse activity. Ginseng total saponin did not inhibit histamine release from rat peritoneal mast cells. All of the ginseng components mentioned above were also tested on RBL-2H3 cells, but none of them inhibited hexosaminidase release from this cell line. These results suggest that Panax ginseng does not have effects on allergic reactions at the level of 50% ethanol extract or total saponin used. All of 8 major saponin components tested ($Rb_1$, $Rb_2$, Rc, Rd, Re, Rf, $Rg_1$, $Rg_2$), did not inhibit lipoxygenase activity and degranulation events.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1984년도 학술대회지
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• pp.185-190
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• 1984

수삼(Panax ginseng C.A.Meyer)의 휘발성 향기성분을 SE-54 fused silica capillary를 이용한 개스크로와 질량분석방법을 이용해서 연구했다. 수삼을 수증기 종류해서 얻어진 증류물을 diethyl ether로 추출해서 농축하고 이 농축물을 중성, 산성, 폐놀성 및 염기성 분획으로 분리했다. 가장 방향이 풍부하고 원 수삼취와 비슷한 중성분획을 분석한 결과 인삼의 주요한 향기성분은 200종 이상 많은 성분중 monoterpene과 sesquiterpene계 성분이었다. Sesquiterpene 화합물은 질량 204를 갖는 azulene, menthene, napthalene계 화합물이었다.

• Journal of Ginseng Research
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• 제22권2호
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• pp.73-81
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• 1998

In order to stabilize the price of fresh ginseng by extension of seasonal variation and marketing structure, and to reduce the cost of production by works of intensive and short term, studies were carried out. As fresh ginseng of 4 years old by the MA (modified atmosphere storage) and CA (controlled atmosphere storage) was stored for 12 week at 4$^{\circ}C$, samples were collected after every 1, 2, 3, 4, 6, 8, 12 weeks for processing red ginseng. Chemical characteristics on ginseng steamed red for the quality evaluation are summarized as follows. The composition of free sugar was consisted of fructose, glucose, sucrose, and maltose in fresh ginseng. And small change was revealed in free sugar composition during the storage period. Glucose and sucrose were largely increased in both treatments of MA (modified atmosphere storage) and CA (controlled atmosphere storage) after 4 week, wherein maltose was decreased. Fifteen different amino acids were identified, and total amount of histamine and arginine were over 40%. Phenylalanine was slightly decreased. As the volatile components in control red ginseng, six different ones including triisopropyl benzene were detected. B-1 ($CO_2$ : $O_2$ : N2=6 : 4.90, DF-100) of CA and E-1 (CPP, DF-100) of MA did not shown triisopropyl benzene as the volatile components. And ${\gamma}$-muurolene, guaiaene, and beta-patchoulene were reduced, but the other components showed the trend of increase.

• Natural Product Sciences
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• 제24권1호
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• pp.1-12
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• 2018

Ginseng (Panax ginseng) is recognized as one of the most valuable medicinal herbs in Asia and it contains diverse phytochemicals that contribute to its pharmacological effects. Although lipids represent a major component of ginseng, ginseng lipids are still far from being fully explored. This review is focused on ginseng lipid components and methodologies of their analysis. The ginseng lipid compounds were categorized according to the structural features of each lipid class. This basic information on ginseng lipid components and the analysis methods will be applicable to authentification or quality control of ginseng products, and development of lipid-based pharmaceuticals and nutraceuticals from ginseng.

• Journal of Ginseng Research
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• 제4권2호
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• pp.121-132
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• 1980

In order to study the effect of Korean ginseng (Panax ginseng C. A. Meyer) components on acetic acid fermentation, ginseng extracts, sucrose, total can de saponins were added to the basal niedium respectively and surface culture was carried out at 30$^{\circ}C$. Lag ime, total acidity of the fermentation broth inhibitors and the degrees of inhibition were determined in tile course of fermentation . 1. Acetic acid fermentation was not inhibited by the addition of less than 1.93% of sucrose but the degree of inhibition was increased slightly by the addition of sucrose more than that. 2. Ginseng extract inhibited acetic acid fermentation slightly, and the degree of inhibition was similar to that of sucrose. Lag time was about 72 hours when a 20% of ginseng extract was added to the basal medium while that of the control was 22hours. 3. The free saponins inhibited acetic acid fermentation considerably, and the degree of inhibition of the saponins was about 400 folds of that of ginseng extracts. An increase of total acidity of the broth which contained 2.905% of the saponins was not observed even after one month. 4. It was presumed that some other components except saponins and sucrose in ginseng extracts counter the inbition effect of saponins on acetic acid fermentation

• Journal of Ginseng Research
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• 제16권1호
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• pp.1-6
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• 1992

Chemical composition was determined to evaluate the quality of Panel ginseng-leaf tea over green teas. Ginseng-leaf tea was shown to contain higher contents of soluble matter, ascorbic acid and lower contents of tannins, as compared to tea leaves. The profiles of ginsenoside and sugar of ginseng-leaf tea were noticeably different from those of ginseng roots and the sample maintained high levels of these components under the manufacturing process. Total unsaturated fatty acids and free amino acids were estimated to be decreased in ginseng-leaf tea as compared to those of ginseng leaves. The compositions of amino acids and minerals in ginseng-leaf tea were similar to those of tea leaves and glutamic acid, aspartic acid, leucine, calcium, potassium, sodium, and copper were found to be major components.

• Journal of Ginseng Research
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• 제15권1호
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• pp.13-20
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• 1991

Ginseng components were examined for their ability to modify immunotoxicity of cyclophosphamide. Ginseng polysaccharide fraction (FO, 300 mg/kg) inhibited decreases in the ratio of spleen to body weight, white blood cells (WBC) count and the number of plaque forming cells (PFC) induced by cyclophosphamide (50 mg/kg, i.p.), and increased these variables in normal mice. Ginseng saponin fraction (50 mg/kg) showed to increase hemoglobin content as well as the number of PFC/spleen in normal mice. on the other hand, Panaxytriol (20 mg/kg) Prevented decrease in mc count by cyclophos phamide. Neither saponin fraction nor panaxytriol had any significant effect on the number of PFC and antibody titers in cyclophosphamide-treated mice. These results suggest that ginseng polysaccharine fraction may reduce the immunotoxicity of cyclophosphamide and may be effective in stimulating immune function in normal mice.