• Title/Summary/Keyword: Giant

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Seroma prevention with topical Abnobaviscum sclerotherapy following excision of giant cervical lipoma

  • Jun Ho Choi;Seung Yeon Choi;Jae Ha Hwang;Kwang Seog Kim;Sam Yong Lee
    • Archives of Craniofacial Surgery
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    • v.24 no.1
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    • pp.10-17
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    • 2023
  • Background: Lipomas are common benign tumors of mesenchymal origin that are composed of mature adipocytes. Giant lipomas have a diameter ≥ 10 cm in one or more dimensions or weigh at least 1,000 g. The surgical excision of a giant lipoma requires extensive dissection, increasing the risk of a seroma, which can cause surgical site complications such as wound infection and necrosis. Sclerotherapy with Abnobaviscum (Viscum album extract) is a relatively new technique used to reduce malignant pleural effusion. In this study, we evaluated the effectiveness of prophylactic sclerotherapy using Abnobaviscum to decrease seroma after giant lipoma excision. Methods: We conducted a retrospective medical record review of patients who underwent surgical excision for giant lipoma of the neck from January 2019 to December 2022. Sclerotherapy was performed on the first postoperative day in patients who consented to the procedure, and Abnobaviscum was instilled through the existing Hemovac drain. We compared the clinical course between those who underwent postoperative sclerotherapy and those who did not. Results: Among the 30 patients who underwent giant lipoma excision, we applied sclerotherapy with Abnobaviscum to 15 patients. The average time from surgery to Hemovac removal was statistically shorter in patients who underwent sclerotherapy (p= 0.004). Furthermore, seroma formation was significantly reduced in patients receiving sclerotherapy (p= 0.003). Conclusion: In patients undergoing giant lipoma excision, sclerotherapy using Abnobaviscum helps reduce postoperative seroma formation during the initial postoperative period. It can be an excellent method to reduce complications related to seroma and attenuate patients' postoperative burden.

Antioxidative and Antimutagenic Activity of Ethanolic Extracts from Giant Embroynic Rices (거대배아미 에탄올 추출물의 항산화활성 및 항변이원성)

  • Kang, Mi-Young;Lee, Yun-Ri;Koh, Hee-Jong;Nam, Seok-Hyun
    • Applied Biological Chemistry
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    • v.47 no.1
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    • pp.61-66
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    • 2004
  • 70% ethanolic extracts were prepared from the three mutant rice cultivars with giant embryo termed Shinsunchal-giant embryonic rice, Whachung-giant embryonic rice and Nampung-giant embryonic rice, and its antioxidative and antimutagenic properties were evaluated and compared. For analysing antioxidativity, various antioxidative indices, such as electron donating ability to DPPH radical, scavenging capacity to hydroxyl radicals generated by Fenton reaction, scavenging capacity to superoxide radicals generated by HPX/XOD system, inhibitory effect on autoxidation of linoleic acid and inhibitory effect on membrane lipid peroxidation derived from rabbit erythrocyte ghost, were determined. For analysing antimutagenicity, suppressive effects on mutagenesis induced by the chemical mutagen, mitomycin C, were measured using E. coli PQ 37 as a indicator cell. The results showed that for both antioxidativity and antimutagenicity the giant embryonic rices were more effective compared to the general cooking rice, Among the giant embryonic rice cultivars, Nampung-giant embryonic rice tended to be most effective, showing its scavenging activity to DPPH radical, superoxide radical and hydroxyl radical, and inhibitory activity to lipid peroxidation was 2,3-, 3,3-, 1.7-, and 2.5-fold greater than those of normal rice, respectively.

Control of an invasive alien species, Ambrosia trifida with restoration by introducing willows as a typical riparian vegetation

  • Lee, Chang-Seok;Cho, Yong-Chan;Shin, Hyun-Cheol;Kim, Gyung-Soon;Pi, Jeong-Hoon
    • Journal of Ecology and Environment
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    • v.33 no.2
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    • pp.157-164
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    • 2010
  • We evaluated the restoration effect by introducing willows as a means of controlling invasions of giant ragweed (Ambrosia trifida L.) on a riparian site. Our preliminary survey demonstrated that a problematic exotic species, giant ragweed and the representative riparian species, Salix koreensis are in competitive exclusive relationship. We planted willows at 1 m intervals on the bank of the Dongmun stream at Munsan, Paju, in Central Western Korea as an experimental restoration practice. We installed two 50 m $\times$ 5 m sized restored and non-restored for this experimental study. The non-restored plots were located on river banks, which were covered with concrete blocks and left in itself without any treatment. The height of willow was measured after each of three consecutive growing seasons and compared with the height of the giant ragweed. Although the height of Salix gracilistyla did not achieve the height of the giant ragweed, the height of S. koreensis surpassed that of giant ragweed in the third year after introduction. The results were also reflected in the relative light intensity on the herb layer of willow stand, and thereby the relative light intensities of stands, which were dominated by S. koreensis or restored by introducing S. koreensis, 1.99 $\pm$ 0.33 (%, mean $\pm$ SD) and 1.92 $\pm$ 0.50 (%, mean $\pm$ SD), respectively were lower than those in the stands treated by S. gracilistyla, 3.01 $\pm$ 0.43 (%, mean $\pm$ SD). The giant ragweed stands receive full sunlight as there are no any vegetation layers higher than the herb layer formed by the giant ragweed. As the result of Detrended Correspondence analysis ordination based on naturally established vegetation, the stands dominated by willows and giant ragweed showed different species composition between both stands. The species composition of the restoratively treated sites resembled the reference sites more than the non-treated sites. The species diversity (H') of the sites restored by introducing S. koreensis and S. gracilistyla was higher than the non-restored site dominated by A. trifida. On the basis of our results, the restoration of riparian vegetation equipped with integrated features could contribute not only to the control of exotic plants including giant ragweed but also to ensure the diversity and stability of riverine ecosystems.

Antioxidant Activity of Ethanolic Extract from Germinated Giant Embryonic Rices (발아 거대배아미 에탄올 추출물의 항산화 활성)

  • Kang, Mi-Young;Kim, Sul-Yi;Koh, Hee-Jong;Nam, Seok-Hyun
    • Applied Biological Chemistry
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    • v.47 no.3
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    • pp.293-299
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    • 2004
  • Antioxidant activity of ethanolic extract of two giant embryonic rices, Nampung giant embryonic rice and Hwachung giant embryonic rice, were investigated mainly focusing on their ability to inhibit lipid peroxidation and scavenge reactive oxygen species in comparison with those of general rice. The results showed that germination process increased reducing power, inhibitory activity on lipid peroxidation and scavenging ability either on superoxide or hydroxyl radicals. Among the cultivars tested, increase in antioxidative action was found to be most prominent for Hwachung giant embryonic rice cultivar. For scavenging of superoxide radicals, the extract from Nampung giant embryonic rice has the most potent activity, however, increasing rate of scavenging activity by germination process was also found to be the greatest for Hwachung giant embryonic rice. We found that the scavenging mechanism for superoxide radicals was attributed to the direct scavenging of the radicals. The scavenging of hydroxyl radicals, the most toxic oxygen radical to biological system, by the rice extracts were also examined, and the results showed that either overall activity or the increasing rate of the activity to scavenge hydroxyl radicals by germination process was the greatest for Hwachung giant embryonic rice. Moreover, the results suggested that the scavenging action to hydroxyl radicals might be mediated by direct quenching of the radicals, not by chelating $Fe^{2+}$. Further studies showed that the antioxidant action of the rice extracts tested in vitro was also operative for suppressing ROS production induced in TPA-stimulated HL-60 cells.

Theoretical Examination of the Effects of Fluctuation of Acoustic Scattering on the Swimming Behavior of Giant Jellyfish (유영행동에 따른 대형 해파리의 음향산란 변동의 이론적 검토)

  • Lee, You-Won;Hwang, Bo-Kyu
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.42 no.2
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    • pp.165-170
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    • 2009
  • Recently, wide spread distribution of the giant jellyfish, Nemopilema nomurai, has occurred in the East China Sea. This increased distribution has caused serious problems in inshore and offshore fisheries in Korea and Japan. As a result, it is necessary to evaluate the damage caused to the fisheries by jellyfish. Accordingly, several hydroacoustic studies have been conducted to estimate the target strength (TS) of the giant jellyfish. However, the effects of fluctuation in the acoustic scattering characteristics on swimming patterns have not yet been elucidated. Therefore, in this study, we theoretically estimated the effects of changes in the acoustic scattering pattern on the swimming behavior of jellyfish using the Distorted Wave Born Approximation (DWBA) model. The results confirmed that acoustic scattering of jellyfish results in a significant change in their swimming pattern. Specifically, our theoretical estimation indicated that the TS of giant jellyfish (d=40 cm) fluctuated until 8.5 dB at 38 kHz, 13.8 dB at 70 kHz, and 15.1 dB at 120 kHz based on changes in their swimming patterns.

A Case of Giant Epidermal Inclusion Cyst (거대 표피 낭종의 치험례)

  • Kim, Keun Sik;Cho, Pil Dong;Shin, Keuk Shun;Oh, Hwa Eun
    • Archives of Plastic Surgery
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    • v.34 no.6
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    • pp.803-806
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    • 2007
  • Purpose: The epidermal cyst is a very common skin lesion which usually occurs in the hairy regions. They are generally small but rarely reach more than 5 cm in diameter. We present a patient with a giant epidermal cyst on buttock area. Methods: A 50-year-old man with a slowly enlarging, huge mass in his left buttock was examined. There was no history of trauma in this area. Physical examination revealed a soft, nontender, $15{\times}15cm$-sized mass in his left buttock. T1-weighted magnetic resonance images demonstrated a well-circumscribed, multilocular cystic lesion with homogeneous, slightly high signal intensity. On T2-weighted images the lesion had wide areas of high signal intensity. The mass was totally excised. Results: A histopathological finding revealed that the cystic wall was lined with whole layers of stratified squamous epithelium. Keratin layers from the surface of the epithelium were seen to be sloughing into the cystic lumen. Multinucleted giant cells were found outside the cystic wall. Conclusion: Herein we report a rare case of giant epidermal cyst occurring on the buttock.

Spontaneous Regression of Extensive Pulmonary Metastasis of Benign Giant Cell Tumor of Bone - A Case Report - (자연 소실된 거대 세포종의 광범위한 폐전이 - 1예 보고-)

  • Park, Ru-Ppo;Lee, Sang-Hoon;Cho, Whan-Sung;Kim, June-Hyuk;Kim, Han-Soo
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.1
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    • pp.39-44
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    • 2004
  • A Giant cell tumor of bone has unusual characteristics of pulmonary metastasis as well as local aggressiveness. Clinical courses of pulmonary metastasis of benign giant cell tumor vary including rapid growth, continuously slow growth or spontaneous regression. We report a case of extensive pulmonary metastasis of giant cell tumor of bone, which regressed spontaneouly.

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A Giant Unruptured Aneurysm of Middle Cerebral Artery Bifurcation Solely Presenting with Seizure - A Case Report - (경련만으로 발현된 중대뇌동맥 분지부의 미파열성 거대 동맥류 - 증례보고 -)

  • Kim, Jae Hoon;Yi, Hyeong Joong;Kim, Kwang Myung;Kim, Jae Min;Kim, Young Soo;Ko, Yong;Oh, Seong Hoon;Oh, Suck Jun
    • Journal of Korean Neurosurgical Society
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    • v.30 no.5
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    • pp.657-661
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    • 2001
  • Intracranial giant aneurysms have been known to cause clinical signs and symptoms, either by rupture, compression of surrounding structures, repeated minor leakage, or cerebral ischemia due to thromboembolism. A giant aneurysm which manifests only a seizure disorder comprises relatively few contributions. The authors present a case of a giant, unruptured aneurysm solely presenting with generalized tonic-clonic type seizure in a 43-year-old man. Brain computed tomogram(CT) and 3-D CT angiogram demonstrated a huge calcified aneurysm at the bifurcation of right middle cerebral artery. Complete neck clipping and aneurysmectomy followed by uneventful neurologic recovery.

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A Metastatic Giant Cell Tumor of the Soft Tissue of the Thoracic Wall - A case report - (흉벽 연부조직에 발생한 전이성 거대세포종 - 1예 보고 -)

  • Shin, Duk-Seop;Lee, Jang-Hoon;Choi, Jun-Hyuk;Chung, Tae-Eun
    • Journal of Chest Surgery
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    • v.40 no.7 s.276
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    • pp.526-528
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    • 2007
  • A giant cell tumor of bone is a benign bone tumor, but has very high local recurrence rate and, very rarely metastasizes to the lung or a distant area. We report a case of a 29-year-old male patient presenting with a metastatic giant cell tumor of the soft tissue of the chest wall, who underwent a total resection of the radius for recurrence of the giant cell tumor. The tumor was not related to any bony structure of the thorax. We resected the tumor with a wide surgical margin. No evidence of malignancy was seen in the frozen and permanent pathological report.