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Antioxidative and Antimutagenic Activity of Ethanolic Extracts from Giant Embroynic Rices  

Kang, Mi-Young (Department of Food Science and Nutrition, Kyungpook National University)
Lee, Yun-Ri (Department of Food Science and Nutrition, Kyungpook National University)
Koh, Hee-Jong (Department of Agronomy, Seoul National University)
Nam, Seok-Hyun (Department of Biological Science, Ajou University)
Publication Information
Applied Biological Chemistry / v.47, no.1, 2004 , pp. 61-66 More about this Journal
Abstract
70% ethanolic extracts were prepared from the three mutant rice cultivars with giant embryo termed Shinsunchal-giant embryonic rice, Whachung-giant embryonic rice and Nampung-giant embryonic rice, and its antioxidative and antimutagenic properties were evaluated and compared. For analysing antioxidativity, various antioxidative indices, such as electron donating ability to DPPH radical, scavenging capacity to hydroxyl radicals generated by Fenton reaction, scavenging capacity to superoxide radicals generated by HPX/XOD system, inhibitory effect on autoxidation of linoleic acid and inhibitory effect on membrane lipid peroxidation derived from rabbit erythrocyte ghost, were determined. For analysing antimutagenicity, suppressive effects on mutagenesis induced by the chemical mutagen, mitomycin C, were measured using E. coli PQ 37 as a indicator cell. The results showed that for both antioxidativity and antimutagenicity the giant embryonic rices were more effective compared to the general cooking rice, Among the giant embryonic rice cultivars, Nampung-giant embryonic rice tended to be most effective, showing its scavenging activity to DPPH radical, superoxide radical and hydroxyl radical, and inhibitory activity to lipid peroxidation was 2,3-, 3,3-, 1.7-, and 2.5-fold greater than those of normal rice, respectively.
Keywords
giant embryonic rice; antioxidativity; antimutagenicity; inhibition of lipid autoxidation;
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