• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.4 no.1
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• pp.59-62
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• 1974

The authors observed, in the routine roentgenographic examination, a rare case of Giant cell Reparative Granuloma found in the mandible of woman 23 years of age who had visited Infirmary of Dental College, Seoul National University' because of the traffic accident. In the serial roentgenograms, Authors had obtained the result as follows; 1. Giant cell Reparative Granuloma occurred below the 20 years of age, and occurred in mandible of female. 2. In roentgenograms, it figures the radiolucent lesion with multilocular apperance. 3. The growing process of Giant cell Reparative Granuloma is not by the neoplastic reaction, but by the local reparative reaction.

• Archives of Plastic Surgery
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• v.32 no.5
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• pp.645-648
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• 2005

Cutaneous horn is a morphologic designation for a projectile, conical, dense hyperkeratotic nodule that resembles the horn of an animal. The lesion varies in size from only a few millimeters to several centimeters, in color(white or yellowish) and in form (straight, curved, or twisted). It arises from a wide range of epidermal lesions, which include benign lesions, premalignant lesions and malignant lesions. An 83-year-old women came to our clinic with a giant cutaneous horn on the right chin and a small horn on the left upper eyelid. The patient had no palpable cervical lymph node. A wide elliptical skin incision was made and the horn was totally excised. In pathology, the giant cutaneous horn on the right chin revealed a moderately differentiated squamous cell carcinoma with subcutis invasion at its base. "Giant cutaneous horns" have often been associated with invasive squamous cell carcinoma. Cutaneous horns are common lesions usually found on the face, rarely larger than 2 cm. As large cutaneous horns are often associated with underlying malignancy, histopathologic examination of the base of the lesion is necessary to rule out carcinoma and full excision is recommended.

• The Journal of the Korean bone and joint tumor society
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• v.19 no.2
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• pp.87-91
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• 2013

Diffuse-type giant cell tumor is relatively rare than localized giant cell tumor. Moreover, diffuse type giant cell tumor is common in intraarticular area, rarely occurs at intramuscular or subcutaneous layer. We experienced 1 case of giant cell tumor within the deltoid muscle. So we report this case with review of the literatures.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.673-676
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• 2016

Background: In the maxillofacial region, giant cell granulomas occur in 2 clinical forms, central and peripheral. Despite histopathological similarity between these 2 forms totally different clinical behaviors have been reported. The present study was undertaken to compare mast cell and vascular concentrations in these pathologic lesions. Materials and Methods: In this cross-sectional descriptive study, 20 pathological samples of central giant cell granuloma (CGCG) and 20 samples of peripheral giant cell granuloma (PGCG) were selected and examined through toluidine blue staining for mast cell assessment and immunohistochemical staining by VEGEF antibody for comparing the number of mast cells. T-test, chi-squared test and backward multivariate linear regression were used for statistical analysis using SPSS 20. Statistical significance was set at P<0.05. Results: This study showed significantly greater VEGF expression and mast cell concentrations in CGCG compared to PGCG cases. Also there was a significant correlation between VEGF expression and the concentration of mast cells. No relation was found between age, sex and site of the lesion and concentration of mast cells or VEGF expression. Conclusions: It is feasible that higher concentrations of mast cells in CGCG versus PGCG samples might lead to more aggressive clinical behavior via vascular proliferation and angiogenesis. However, other biologic mechanisms should be considered in this situation.

• The Journal of the Korean bone and joint tumor society
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• v.7 no.4
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• pp.144-150
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• 2001

It is not uncommon for sarcomatous transformation of giant cell tumor of bone to occur after radiation, but osteosarcoma arising from giant cell tumor after surgical treatment is very rare and remains an aggressive form of sarcoma of bone with high mortality rate. We experienced 2 cases in whom a osteosarcoma developed long after benign giant cell tumor of bone was removed surgically from the same site. Malignant transformation was presented at 2 years 1 month and 9 years 8 months each after initial surgery. We describe our experience concerning clinical features, methods of treatment and outcomes of osteosarcoma arising from giant cell tumor.

• The Korean Journal of Cytopathology
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• v.5 no.2
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• pp.172-175
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• 1994

Anaplastic carcinoma of the thyroid is one of the most malignant tumors and survival for longer than three years after diagnosis is exceptional. Multinucleated giant cells of osteoclastlike appearance are seen un some of the anaplastic carcinoma, but only three cases in which the diagnosis was made by fine needle aspiration (FNA) cytology are reported in the international literature. We experienced a case of anaplastic carcinoma with osteoclastlike giant cells in a 66-yr-old female, diagnosed by FNA cytology. The smears revealed two cell populations: multinucleated giant cells and large polygonal or spindle shaped malignant cells. The FNA cytodiagnosis of anaplastic thyroid carcinoma containing osteoclastlike giant cells was substantiated by subsequent biopsy.

• The Korean Journal of Cytopathology
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• v.19 no.1
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• pp.57-64
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• 2008

Giant cell tumor of the tendon sheath (GCTTS) is a slowly growing, benign soft tissue tumor. The tumors occur predominantly on the hands and feet. Although the clinical and histopathologic features are well-defined, only a few reports have described the cytologic appearance of this entity. A 26-year-old woman presented with a gradually developing circumscribed soft tissue mass near the proximal phalanx of her left little finger for one year. Imprint and fine needle aspiration (FNA) smears were obtained from the excisional biopsy specimen. The imprint smears were composed of predominantly singly dispersed bland mononuclear cells and several giant cells. The mononuclear cells were polygonal to round, and they showed a histiocyte-like appearance. Osteoclast-type multinucleated giant cells of various sizes were randomly scattered throughout the smears, and these cells contained 3 to 50 nuclei. Nuclear atypia and pleomorphism were absent in both the single and giant cells. Loose aggregates of hemosiderin-laden macrophages and binuclear stromal cells were also seen. The cytologic features of the FNA smears were similar with those of the imprint, Additionally, the FNA smears contained several clumps of densely collagenous stromal tissue that were seldom noted in previously reported cytologic material. The cytologic features were well-correlated with the concurrent histologic findings and the diagnosis of GCTTS was made. When the clinical and radiologic datas are integrated, the diagnosis of GCTTS can be strongly suggested, based on the pre-operative cytologic specimen.

• Journal of Veterinary Clinics
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• v.36 no.3
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• pp.176-179
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• 2019

A giant prostatic urethral calculus has not been previously reported in dogs and should be distinguished from prostatic calculus. A 7-year-old castrated male Maltese dog with a 2-month history of relapsing hematuria and urinary incontinence with slowly progressing paraphimosis was referred. On abdominal radiography and ultrasonography, there was a giant calculus in the region of prostate or urethra, one left ureteral calculus, one urinary bladder calculus, and two penile urethral calculi. On computed tomography for evaluating the accurate location and planning the surgical approach, the giant calculus was located at the prostatic urethra. The calculi in urinary bladder, prostatic and penile urethra were surgically removed. These calculi were mixed-type of calcium oxalate monohydrate, struvite and calcium phosphate carbonate. On the basis of the urolith analysis and urine bacterial culture results, antibiotics and prescription diet were adjusted. At the 3-month follow-up, there were no clinical sings but paraphimosis was still remained, and ultrasonography revealed newly-formed, small urethral calculi at the prostatic urethra. This is the first report to describe the case of a canine giant prostatic urethral calculus and its clinical signs, diagnostic imaging findings, treatment, and outcome. CT may be useful to assess the accurate location and surgical approach for such calculi.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• v.61 no.11
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• pp.615-618
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• 2018

The central giant cell granuloma is a benign tumor seen generally in the mandible, but rarely in other cranial bones. Herein, we present a 51-year-old man with central giant cell granuloma in the right zygomatic bone. Physical and radiologic examinations of the central giant cell granuloma in the zygomatic bone showed that specific and preoperative diagnosis is usually difficult. Therefore, clinicians should consider the possibility that central giant cell granuloma may occur in the zygomatic bone mimicking other more frequently observed lesions.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.60 no.1
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• pp.18-26
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• 2024

In this study, we estimated the distribution density of giant jellyfish in coastal waters of Korea in 2023 and compared the occurrence of giant jellyfish over four years. In May, the giant jellyfish were mainly distributed in the waters of the Yangtze River outflow, and in July, they were highly distributed in the west of Jeju Island and near the south coast of Korea. In addition, when comparing the distribution densities of giant jellyfish in Korea over four years, both acoustic and sighting surveys showed that the highest density of jellyfish occurred in 2021.