The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Fine Needle Aspiration Cytology of Anaplastic Carcinoma with Osteoclastlike Giant Cells of the Thyroid

파골세포 모양의 다핵거대세포를 지닌 갑상선 역행성암종의 세침흡인 세포학적 소견

  • Lee, Ji-Shin (Department of Pathology, Chonnam University Medical School) ;
  • Ko, Hyang-Mi (Department of Pathology, Chonnam University Medical School) ;
  • Lee, Min-Cheol (Department of Pathology, Chonnam University Medical School) ;
  • Park, Chang-Soo (Department of Pathology, Chonnam University Medical School) ;
  • Juhng, Sang-Woo (Department of Pathology, Chonnam University Medical School)
  • 이지신 (전남대학교 의과대학 병리학교실) ;
  • 고향미 (전남대학교 의과대학 병리학교실) ;
  • 이민철 (전남대학교 의과대학 병리학교실) ;
  • 박창수 (전남대학교 의과대학 병리학교실) ;
  • 정상우 (전남대학교 의과대학 병리학교실)
  • Published : 1994.12.30
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Abstract

Anaplastic carcinoma of the thyroid is one of the most malignant tumors and survival for longer than three years after diagnosis is exceptional. Multinucleated giant cells of osteoclastlike appearance are seen un some of the anaplastic carcinoma, but only three cases in which the diagnosis was made by fine needle aspiration (FNA) cytology are reported in the international literature. We experienced a case of anaplastic carcinoma with osteoclastlike giant cells in a 66-yr-old female, diagnosed by FNA cytology. The smears revealed two cell populations: multinucleated giant cells and large polygonal or spindle shaped malignant cells. The FNA cytodiagnosis of anaplastic thyroid carcinoma containing osteoclastlike giant cells was substantiated by subsequent biopsy.

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