• Title/Summary/Keyword: Genetic program

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Literature Review of Development of the Genetic Counseling Education Program for Genetic Specialized Nurse (유전상담 전문간호사 교육프로그램 개발에 대한 문헌고찰)

  • Kim, Mi-Young;Byeon, Young-Soon;Yoon, Hee-Sang
    • Journal of Korean Biological Nursing Science
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    • v.7 no.1
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    • pp.15-28
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    • 2005
  • Purpose: With post-Genome Project, nurses must be able to incorporate genetic knowledge into their practice. The purpose of the present study aimed at providing the basic information needed to establish an education program for the training of nurses specialized in genetic counseling by comparing and analyzing the education contents in genetics of the various domestic and foreign nursing education institutions, identifying the problems of the existing programs, and investigating the current state of domestic genetic counseling programs. Result: The results of literature review were summarized as follows: Common curricula contents in Korea, Japan and U.S.A. were basic genetic knowledge, genetic counseling and prenatal diagnosis. However, In Korea the curriculum was not included legal, ethical, and social issues. In U.S.A. the course was focused on health promotion related to genetics. The expanded role of nurses is to provide the genetic counseling for clients and their families. So, this articles provided a sample of the new genetic counseling program for nurses which are included basic genetics, genetic counseling, nurse's role and knowledge, legal, ethical, social issues and practicum. Conclusion: this study suggests that this educational program is to brought up genetic specialized nurses in the master's course in the near future.

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Productivity effects of Hanwoo genetic improvement program

  • Jae Bong Chang;Sanghyen Chai
    • Korean Journal of Agricultural Science
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    • v.50 no.4
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    • pp.869-881
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    • 2023
  • A genetic improvement program in Korea was implemented to improve the performance of Hanwoo cattle by generating livestock with genetically desirable economic characteristics. In particular, in response to external changes, such as the expansion of Free Trade Agreement (FTA), the livestock genetic improvement program has increased farm income by improving the productivity and quality of Hanwoo cattle. Using production cost data from Statistics Korea, the total input and output indices of Hanwoo feeding cattle from 2008 - 2021 were estimated and the growth and productivity changes were analyzed. The productivity change measures results were used to estimate the cumulative effects of the Hanwoo genetic improvement program on quality improvement, another purpose of the program, using a finite distributed lag model. The average annual increase in output (market weight) of Hanwoo was 0.9%. However, total input increased by 1.6%, resulting in a 0.6% decline in total factor productivity. In contrast, the Hanwoo genetic improvement program contributed significantly to the production of high quality beef, rather than contributing to improved productivity of the cattle. Hanwoo carcass weight, which is used as a performance indicator for the livestock genetic improvement program, has significantly improved and is projected to increase at a slower rate. The collective findings indicate the need for new performance indicators that can comprehensively indicate the performance of the genetic improvement of Hanwoo.

The First Korean Cancer Genetic Counseling Program for Nurses (국내 종양유전상담 간호사를 위한 단기 교육프로그램 개발)

  • Choi, Kyung-Sook;Anderson, Gwen;Jun, Myung-Hee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.12 no.1
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    • pp.104-114
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    • 2006
  • Genetic knowledge for oncology nurses is important in Korea because oncologists are incorporating genetic counseling and genetic testing into their practice. The purpose of this paper is to describe our method of developing the first academic cancer genetic risk assessment and counseling course for Korean nurses. A one-week (non-credit) cancer genetics counseling program was constructed for master's level Korean oncology nurses. The course emphasized basic genetic concepts and principles the genetics of cancer; hereditary cancer syndromes; family history assessments; pedigree construction; risk calculation; surveillance recommendations and treatment options ethical, legal, social, and psychological issues inherent in genetic testing. The goals of this program are to: 1) provide a comprehensive knowledge base for nurses who are currently expanding their scope of practice into the genetic counseling role 2) introduce this knowledge to nurses who want to use it in their practice; and 3) provide cancer genetic knowledge and resources to Korean nursing faculty who plan to incorporate this knowledge into existing master's courses. This academically-based course is recognized as valuable by nurses, nursing faculty, and physicians. With this new knowledge nurses can begin toexpand their role in delivering comprehensive cancer care services.

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Indigenous Thai Beef Cattle Breeding Scheme Incorporating Indirect Measures of Adaptation: Sensitivity to Changes in Heritabilities of and Genetic Correlations between Adaptation Traits

  • Kahi, A.K.;Graser, H.U.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.8
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    • pp.1039-1046
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    • 2004
  • A model Indigenous Thai beef cattle breeding structure consisting of nucleus, multiplier and commercial units was used to evaluate the effect of changes in heritabilities of and genetic correlations between adaptation traits on genetic gain and profitability. A breeding objective that incorporated adaptation was considered. Two scenarios for improving both the production and the adaptation of animals where also compared in terms of their genetic and economic efficiency. A base scenario was modelled where selection is for production traits and adaptation is assumed to be under the forces of natural selection. The second scenario (+Adaptation) included all the information available for base scenario with the addition of indirect measures of adaptation. These measures included tick count (TICK), faecal egg count (FEC) and rectal temperature (RECT). Therefore, the main difference between these scenarios was seen in the records available for use as selection criteria and hence the level of investments. Additional genetic gain and profitability was generated through incorporating indirect measures of adaptation as criteria measured in the breeding program. Unsurprisingly, the results were sensitive to the changes in heritabilities and genetic correlations between adaptation traits. However, there were more changes in the genetic gain and profitability of the breeding program when the genetic correlations of adaptation and its indirect measures were varied than when the correlations between these measures were. The changes in the magnitudes of the genetic gain and profit per cow stresses the importance of using reliable estimates of these traits in any breeding program.

Program Development of Genetic Analysis for Diallel Cross Experiment

  • Kim, Seo Young;Bae, Jong Sung
    • Communications for Statistical Applications and Methods
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    • v.9 no.3
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    • pp.675-682
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    • 2002
  • In this study, we develop the statistical analysis program for genetic analysis of diallel crosses data by SAS/MACRO, SAS/IML. Genetic analysis is to estimate of genetics parameters and heredity with reciprocal cross and without reciprocal cross. Statistical analysis program solve the problem of the difficulties on the data analysis in field denetics and breeding Therefore the user whoever want to analysis of data on genetics and breeding easily conduct the work saving time and suffering.

Optimum Design of Diameters of Marine Propulsion Shafting by Binary-Coded Genetic Algorithm and Modal Analysis Method (이진코딩 유전알고리즘과 모드해석법을 이용한 선박 추진축계의 직경 최적설계)

  • Choi, Myung-Soo;Moon, Deok-Hong;Seol, Jong-Ku
    • Journal of Power System Engineering
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    • v.7 no.3
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    • pp.29-34
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    • 2003
  • Genetic algorithm is a optimization technique based on the mechanics of natural selection and natural genetics. Global optimum solution can be obtained efficiently by operations of reproduction, crossover and mutation in genetic algorithm. The authors developed a computer program which can optimize marine propulsion shafting by using binary-coded genetic algorithm and modal analysis method. In order to confirm the effectiveness of the developed computer program, we apply the program to a optimum design problem which is to obtain optimum diameters of intermediate shaft and propeller shaft in marine propulsion shafting. Objective function is to minimize total mass of shafts and constraints are that torsional vibration stresses of shafts in marine propulsion shafting can not exceed the permissible torsional vibration stresses of the ship classification society. The computational results by the program were compared with those of conventional design technique.

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A Review on Professional non-MD Genetic Counselors for Education and Accreditation in Korea (비의사 전문 유전상담사의 교육 및 자격의 인증을 위한 소고)

  • Kim, Hyon J.;Doh, Seong Tak
    • Korean Journal of Clinical Laboratory Science
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    • v.41 no.3
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    • pp.93-104
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    • 2009
  • This short review was aimed to provide the information for the people who are interested in genetic counselor education and certification system in Korea. A large part of this study is indebted to HJ Kim's articles on the genetic counselor system, the global standards of genetic counseling curriculums, training program accreditation (TPA), and a certification process for genetic counselors (CPGC) in the US and Japan. The US and Japanese educational systems showed a high degree of similarities in curriculum, accreditation, and certification programs. Based upon this review, we hereby propose that the Korean Society for Medical Genetics should take a key role in providing the TPA and CPGC for non-MD genetic counselors. Requirement for the entrance to a Master's degree genetic counseling program should be open to successful four year undergraduate students for all areas, provided the candidates demonstrate the abilities to master the graduate level study in human genetics, statistics, psychology, and other required subjects. Besides accredited program graduates, eligibility for certification should also include the qualified candidates of genetic counseling with no formally approved education, but with a sufficient amount of clinical experience.

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A Study on Genetic Counseling Curriculum, Accreditation of the Training Program, and the Certification Process of Genetic Counselors in Korea (유전상담 교육프로그램 개발과 전문유전상담사 학회인증제도에 관한 연구)

  • Choi, Jee-Yeong;Kim, Hyon-J.
    • Journal of Genetic Medicine
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    • v.6 no.1
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    • pp.38-55
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    • 2009
  • Purpose: This study was undertaken to provide the framework for development of a genetic counseling training program, and an accreditation and certification process suitable for non-M.D. genetic counselors in Korea. Materials and Methods: Global standards of genetic counseling curriculums, training program accreditation (TPA), and the certification process for genetic counselors (CPGC) in the U.S.A and Japan were reviewed, and a questionnaire survey was performed to elicit opinions among health-care providers including physicians, nurses, technicians, researchers, and educators. In addition, input from professional communities, including the Korean Society of Medical Genetics (KSMG) and Institute for Genetic Testing Evaluation, was sought in formulating the framework of this study. Results: Comparison of U.S.A. and Japan educational systems showed similarities in curriculum, accreditation, and certification programs. Analysis of 117 respondents opinions showed a high level of agreement in the area of global standards; 88% indicated that KSMG should be in charge of TPA and CPGC, while 77% favored a certification exam composed of both written exam and interview components. Conclusion: Based upon this study we propose that the KSMG should be in charge of providing the TPA and CPGC for non-MD genetic counselors. Requirements for the entrance to a Master's degree genetic counseling program should be open to successful four year undergraduate students in all areas, provided the candidates demonstrate the abilities to master the graduate level of study in human genetics, clinical genetics, statistics, psychology, and other required subjects. Eligibility for certification should include qualified candidates of genetic counseling with no formally approved education, but a sufficient amount of clinical experience, in addition to accredited program graduates. Certification examinations should be carried out every two years and the certification should be good for five years, as is the case in Japan.

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A Study of the Curriculum of Genetics Nursing Education (유전간호교육 교과과정에 관한 연구)

  • Choi, Kyung-Sook;Kim, Hyun-Jung;Jang, Eun-Sil;Park, Jung-Ae
    • Asian Oncology Nursing
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    • v.10 no.1
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    • pp.103-111
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    • 2010
  • Purpose: This study was undertaken to establish the framework for development of the curriculum of genetics in Nursing Education. Methods: The Internet search, literature review of the US system of genetic nurses, genetic graduate nursing education programs and curricula for nurse in Korea were reviewed and analyzed. Results: American Nurses genetic system consists of APNG and the GCS and all the APNG credential provided by the GNCC of ISONG. The curriculums of genetic nursing education in the US are mainly conducted in of master's program and genetically related subjects consists of basic genetics subjects, basic applied genetics subjects, genetics in nursing subjects and practical training subjects. Lastly a genetic nursing education program in Korea 44 hr of lectures and practical training of 4 hr is composed of basic genetics, genetic cancer, genetics in nursing and practicum in the computer lab and online include family history assessment, pedigree construction, breast and colorectal cancer risk calculations, and ELSI discussions. Conclusion: This study suggested that genetic nursing education course needs in master's program as detailed subjects. Also the establishment of the genetic nurse system is an urgent needed.

Genetic diversity of Indonesian cattle breeds based on microsatellite markers

  • Agung, Paskah Partogi;Saputra, Ferdy;Zein, Moch Syamsul Arifin;Wulandari, Ari Sulistyo;Putra, Widya Pintaka Bayu;Said, Syahruddin;Jakaria, Jakaria
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.4
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    • pp.467-476
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    • 2019
  • Objective: This research was conducted to study the genetic diversity in several Indonesian cattle breeds using microsatellite markers to classify the Indonesian cattle breeds. Methods: A total of 229 DNA samples from of 10 cattle breeds were used in this study. The polymerase chain reaction process was conducted using 12 labeled primers. The size of allele was generated using the multiplex DNA fragment analysis. The POPGEN and CERVUS programs were used to obtain the observed number of alleles, effective number of alleles, observed heterozygosity value, expected heterozygosity value, allele frequency, genetic differentiation, the global heterozygote deficit among breeds, and the heterozygote deficit within the breed, gene flow, Hardy-Weinberg equilibrium, and polymorphism information content values. The MEGA program was used to generate a dendrogram that illustrates the relationship among cattle population. Bayesian clustering assignments were analyzed using STRUCTURE program. The GENETIX program was used to perform the correspondence factorial analysis (CFA). The GENALEX program was used to perform the principal coordinates analysis (PCoA) and analysis of molecular variance. The principal component analysis (PCA) was performed using adegenet package of R program. Results: A total of 862 alleles were detected in this study. The INRA23 allele 205 is a specific allele candidate for the Sumba Ongole cattle, while the allele 219 is a specific allele candidate for Ongole Grade. This study revealed a very close genetic relationship between the Ongole Grade and Sumba Ongole cattle and between the Madura and Pasundan cattle. The results from the CFA, PCoA, and PCA analysis in this study provide scientific evidence regarding the genetic relationship between Banteng and Bali cattle. According to the genetic relationship, the Pesisir cattle were classified as Bos indicus cattle. Conclusion: All identified alleles in this study were able to classify the cattle population into three clusters i.e. Bos taurus cluster (Simmental Purebred, Simmental Crossbred, and Holstein Friesian cattle); Bos indicus cluster (Sumba Ongole, Ongole Grade, Madura, Pasundan, and Pesisir cattle); and Bos javanicus cluster (Banteng and Bali cattle).