• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권6호
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• pp.2889-2909
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• 2017

Wireless sensor networks (WSNs) have attracted lots of attention in recent years due to their potential for various applications. In this paper, we seek how to efficiently deploy relay nodes into traditional static WSNs with constrained locations, aiming to satisfy specific requirements of the industry, such as average energy consumption and average network reliability. This constrained relay node deployment problem (CRNDP) is known as NP-hard optimization problem in the literature. We consider addressing this multi-objective (MO) optimization problem with an improved Artificial Bee Colony (ABC) algorithm with a linear local search (MOABCLLS), which is an extension of an improved ABC and applies two strategies of MO optimization. In order to verify the effectiveness of the MOABCLLS, two versions of MO ABC, two additional standard genetic algorithms, NSGA-II and SPEA2, and two different MO trajectory algorithms are included for comparison. We employ these metaheuristics on a test data set obtained from the literature. For an in-depth analysis of the behavior of the MOABCLLS compared to traditional methodologies, a statistical procedure is utilized to analyze the results. After studying the results, it is concluded that constrained relay node deployment using the MOABCLLS outperforms the performance of the other algorithms, based on two MO quality metrics: hypervolume and coverage of two sets.

• 한국지능시스템학회논문지
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• 제17권6호
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• pp.792-798
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• 2007

본 논문에서는 학습기법을 사용하지 않고 패턴분류의 성능을 최대화하면서 규칙의 수를 줄일 수 있는 통계적 정보기반 계층적 퍼지-러프 분류방법을 제안한다. 제안된 방법에서 통계적 정보는 계층적 퍼지-러프 분류 시스템에서 각 계층의 입력부 퍼지집합의 분할 구간을 추출하기 위해서 사용되었고, 러프집합은 통계적 정보로부터 추출된 분할 구간들과 연관된 퍼지 if-then 규칙의 수를 최소화하기 위해서 사용되었다. 제안된 방법의 효과성을 보이기 위해 Fisher의 IRIS 데이터를 사용한 기존 패턴분류 방법의 분류 정확도와 규칙들의 수를 비교하였다. 그 결과, 제안된 방법은 기존 방법들의 분류 성능과 유사함을 확인할 수 있었다.

• IMMUNE NETWORK
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• 제5권2호
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• pp.110-116
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• 2005

Background: As an attempt to develop a strategy to improve the protective immune response to GM-CSF-secreting CT26 (GM-CSF/CT26) tumor vaccine, we have investigated whether the apoptogenic treatment of GM-CSF/CT26 prior to vaccination enhances the induction of anti-tumor immune response in mouse model. Methods: A carcinogeninduced mouse colorectal tumor, CT26 was transfected with GM-CSF gene using a retroviral vector to generate GM-CSF-secreting CT26 (CT26/GM-CSF). The CT26/GM-CSF was treated with ${\gamma}$-irradiation or mitomycin C to induce apoptosis and vaccinated into BALB/c mice. After 7 days, the mice were injected with a lethal dose of challenge live CT26 cells to examine the protective effect of tumor vaccination in vivo. Results: Although both apoptotic and necrotic CT26/GM-CSF vaccines were able to enhance anti-tumor immune response, apoptotic CT26/GM-CSF induced by pretreatment with ${\gamma}$-irradiation (50,000 rads) was the most potent in generating the anti-tumor immunity, and thus 100% of mice vaccinated with the apoptotic cells remained tumor free for more than 60 days after tumor challenge. Conclusion: Apoptogenic pretreatment of GM-CSF-secreting CT26 tumor vaccine by ${\gamma}$-irradiation (50,000 rads) resulted in a significant enhancement in inducing the protective anti-tumor immunity. A rapid induction of apoptosis of CT26/GM-CSF tumor vaccine at the vaccine site might be critical for the enhancement in anti-tumor immune response to tumor vaccine.

• 한국지능시스템학회논문지
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• 제18권5호
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• pp.685-691
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• 2008

퍼지 규칙기반 분류 시스템에서 위한 퍼지 분할 경계들의 선택은 중요하고 어려운 문제이다. 그래서 이들을 효과적으로 결정하기 위해서 신경망, 유전자알고리즘 등과 같은 학습과정에 기반을 둔 다양한 방법들이 제안되었고, 이전 연구에서는 이들 방법에 대한 문제점을 지적하고 이를 개선하기 위하여 중첩 형태에서 퍼지 분할을 결정할 수 있는 방법에 대해서 논의하였다. 본 논문에서는 이전 연구의 방법을 3가지 형태의 분류 경계들, 즉 비중첩, 중첩, 1점 인접 형태로 확장하였다. 또한 이들을 학습에 의존하지 않고 주어진 데이터로부터 얻어진 통계적 정보만을 사용하여 결정하는 방법을 제안하고, 이를 패턴 분류 문제에 적용하여 제안된 방법의 효용성을 보인다.

• Composites Research
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• 제24권2호
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• pp.38-45
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• 2011

본 논문에서는 유리섬유 강화 복합재 적층판으로 이루어진 단일층 Dallenbach layer의 전파흡수체의 최적화 기법을 제시하고 그 성능을 분석하였다. 복합재 적층판의 전기적 특성을 제어하기 위해서 탄소나노튜브(CNT)를 혼합한 프리프레그를 사용하였다. 최적화 설계 기법은 유전자 알고리즘을 사용하였으며, 이를 이용하여 다양한 주파수에서 흡수체를 설계하고, 복합재의 두께 및 CNT 함유율을 최적화하였다. CNT 함유율의 최적화를 위해서는 복합재의 복소 유전율의 수치적 모델이 사용되었다. 전파흡수체의 최적설계에서 주파수에 따라서 CNT 함유율은 비례하여 증가하고, 흡수체의 두께는 반비례하여 감소한다. 흡수체의 -10 dB 흡수대역폭은 흡수체가 설계된 중심주파수에 비례하여 증가한다. 설계된 흡수체의 검증을 위해서 10 GHz에서 중심주파수를 갖는 흡수제를 제조하고 그 성능을 평가하였다. 복합재 적층판의 복소 유전율과 전파흡수체의 반사손실은 벡터회로망분석기와 7 mm 동축관을 이용하여 측정하였다. 복합재의 두께와 복소 유전율에 있어서의 측정된 값과 예측치의 차이에 의해서 중심주파수의 이동, 중심주파수에서의 반사손실의 감쇄, 흡수대역폭의 감소가 발생하였다.

• 한국정보통신학회논문지
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• 제14권11호
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• pp.2514-2520
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• 2010

본 논문은 진화기법을 이용하여 최적의 보안 대응전략을 자동생성 하는 방법의 제안을 목적으로 한다. 정보통신 환경에 대한 침해에 의한 피해가 급증함에 따라 다양한 보안 기술에 대한 연구가 활발히 이루어지고 있다. 그러나 다양한 네트워크 환경에 대한 보안 기술들의 연통 상황을 고려한 최적의 대응 전략을 생성하는데 어려움이었다. 따라서 본 논문에서는 대응방법을 유전자로 표현하여 유전 알고리즘을 적용함으로써 대응방법들에 대한 최적의 조합으로서 최적 대응 전략을 생성하였다. 또한 시뮬레이션을 이용하여 다양한 상황에 대한 대용방법의 적용에 따른 취약성을 정량적으로 평가함으로써 적합도를 평가하였다. 끝으로 제안한 방법을 구현한 시스템에 대한 실험을 통하여 타당성을 검토하였다.

• Geomechanics and Engineering
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• 제11권4호
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• pp.571-585
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• 2016

The crest of the Pubugou central core rockfill dam (CCRD) cracked in the first and second impounding periods. To evaluate the safety of the Pubugou CCRD, an inversion analysis of the constitutive model parameters for rockfill materials is performed based on the in situ deformation monitoring data. The aim of this work is to truly reflect the deformation state of the Pubugou CCRD and determine the causes of the dam crest cracks. A novel real-coded genetic algorithm based upon the differences in gene fragments (DGFX) is proposed. It is used in combination with the radial based function neural network (RBFNN) to perform the parameters back analysis. The simulated settlements show good agreements with the monitoring data, illustrating that the back analysis is reasonable and accurate. Furthermore, the deformation gradient of the dam crest has been analysed. The dam crest has a great possibility of cracking due to the uncoordinated deformation, which agrees well with the field investigation. The deformation gradient decreases to the value lower than the critical one and reaches a stable state after the second full reservoir.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10355-10361
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• 2015

Background: MicroRNAs (miRNAs) are small non-coding RNA molecules found in multicellular eukaryotes which are implicated in development of cancer, including cutaneous squamous cell carcinoma (cSCC). Expression is controlled by transcription factors (TFs) that bind to specific DNA sequences, thereby controlling the flow (or transcription) of genetic information from DNA to messenger RNA. Interactions result in biological signal control networks. Materials and Methods: Molecular components involved in cSCC were here assembled at abnormally expressed, related and global levels. Networks at these three levels were constructed with corresponding biological factors in term of interactions between miRNAs and target genes, TFs and miRNAs, and host genes and miRNAs. Up/down regulation or mutation of the factors were considered in the context of the regulation and significant patterns were extracted. Results: Participants of the networks were evaluated based on their expression and regulation of other factors. Sub-networks with two core TFs, TP53 and EIF2C2, as the centers are identified. These share self-adapt feedback regulation in which a mutual restraint exists. Up or down regulation of certain genes and miRNAs are discussed. Some, for example the expression of MMP13, were in line with expectation while others, including FGFR3, need further investigation of their unexpected behavior. Conclusions: The present research suggests that dozens of components, miRNAs, TFs, target genes and host genes included, unite as networks through their regulation to function systematically in human cSCC. Networks built under the currently available sources provide critical signal controlling pathways and frequent patterns. Inappropriate controlling signal flow from abnormal expression of key TFs may push the system into an incontrollable situation and therefore contributes to cSCC development.

• 대한전기학회논문지:시스템및제어부문D
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• 제49권7호
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• pp.378-388
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• 2000

In this paper, we propose Fuzzy Polynomial Neural Networks(FPNN) based on Polynomial Neural Networks(PNN) and Fuzzy Neural Networks(FNN) for model identification of complex and nonlinear systems. The proposed FPNN is generated from the mutually combined structure of both FNN and PNN. The one and the other are considered as the premise part and consequence part of FPNN structure respectively. As the consequence part of FPNN, PNN is based on Group Method of Data Handling(GMDH) method and its structure is similar to Neural Networks. But the structure of PNN is not fixed like in conventional Neural Networks and self-organizing networks that can be generated. FPNN is available effectively for multi-input variables and high-order polynomial according to the combination of FNN with PNN. Accordingly it is possible to consider the nonlinearity characteristics of process and to get better output performance with superb predictive ability. As the premise part of FPNN, FNN uses both the simplified fuzzy inference as fuzzy inference method and error back-propagation algorithm as learning rule. The parameters such as parameters of membership functions, learning rates and momentum coefficients are adjusted using genetic algorithms. And we use two kinds of FNN structure according to the division method of fuzzy space of input variables. One is basic FNN structure and uses fuzzy input space divided by each separated input variable, the other is modified FNN structure and uses fuzzy input space divided by mutually combined input variables. In order to evaluate the performance of proposed models, we use the nonlinear function and traffic route choice process. The results show that the proposed FPNN can produce the model with higher accuracy and more robustness than any other method presented previously. And also performance index related to the approximation and prediction capabilities of model is evaluated and discussed.

• Nuclear Engineering and Technology
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• 제42권2호
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• pp.219-230
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• 2010

In nuclear power plants (NPPs), periodic sensor calibrations are required to assure that sensors are operating correctly. By checking the sensor's operating status at every fuel outage, faulty sensors may remain undetected for periods of up to 24 months. Moreover, typically, only a few faulty sensors are found to be calibrated. For the safe operation of NPP and the reduction of unnecessary calibration, on-line instrument calibration monitoring is needed. In this study, principal component-based auto-associative support vector regression (PCSVR) using response surface methodology (RSM) is proposed for the sensor signal validation of NPPs. This paper describes the design of a PCSVR-based sensor validation system for a power generation system. RSM is employed to determine the optimal values of SVR hyperparameters and is compared to the genetic algorithm (GA). The proposed PCSVR model is confirmed with the actual plant data of Kori Nuclear Power Plant Unit 3 and is compared with the Auto-Associative support vector regression (AASVR) and the auto-associative neural network (AANN) model. The auto-sensitivity of AASVR is improved by around six times by using a PCA, resulting in good detection of sensor drift. Compared to AANN, accuracy and cross-sensitivity are better while the auto-sensitivity is almost the same. Meanwhile, the proposed RSM for the optimization of the PCSVR algorithm performs even better in terms of accuracy, auto-sensitivity, and averaged maximum error, except in averaged RMS error, and this method is much more time efficient compared to the conventional GA method.