• 산업공학
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• 제25권3호
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• pp.365-375
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• 2012

An Unmanned Aerial Vehicle (UAV) is a powered pilotless aircraft, which is controlled remotely or autonomously. UAVs are an attractive alternative for many scientific and military organizations. UAVs can perform operations that are considered to be risky or uninhabitable for humans. UAVs are currently employed in many military missions and a number of civilian applications. For accomplishing the UAV's missions, guarantee of survivability should be preceded. The main objective of this study is to suggest a mathematical programming model and a $A^*PS$_PGA (A-star with Post Smoothing_Parallel Genetic Algorithm) for Multiple UAVs's path planning to maximize survivability. A mathematical programming model is composed by using MRPP (Most Reliable Path Problem) and MTSP (Multiple Traveling Salesman Problem). After transforming MRPP into Shortest Path Problem (SPP),$A^*PS$_PGA applies a path planning for multiple UAVs.

• Asian-Australasian Journal of Animal Sciences
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• 제21권12호
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• pp.1696-1702
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• 2008

In order to learn the origin of the Chinese Mongolian horse, we analyzed polymorphisms within the mtDNA D-loop variable region in 305 horses of 6 types of 3 different breeds, including one imported breed, one cultivated breed and 4 types of one local breed. We detected 13 different haplotypes, and subsequent sequence analysis showed that all 6 horse types were genetically diverse. By constructing a cladogram of mtDNA D-loop sequences from the 6 horse types along with homologous sequences from several other horse types obtained from GenBank, we showed that Chinese Mongolian horses have a close genetic relationship with other horse types from Mongolia. We also speculate that several Chinese Mongolian horses descended from Przewalskii horse. Additionally, the 13 haplotypes were dispersed throughout the cladogram, suggesting that Chinese Mongolian horses likely originated from multiple female ancestors. A phylogenetic map of the 6 horse types showed that the genetic relationship between the local Wuzhumuqin and Wushen types were the closest. The Xinihe and Baerhu were also closely related to each other, and slightly more distantly related to the cultivated Sanhe breed. All five of the local Chinese horse types had a much more distant relationship with the imported Thoroughbred breed.

• 환경영향평가
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• 제20권5호
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• pp.663-673
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• 2011

In the face of accelerating biodiversity loss and its significance in our coexistence with nature, biodiversity is becoming more crucial in sustainable development perspective. To estimate biodiversity in the future which provides valuable information for decision making system especially in the national level, a quantitative approach must be studied forehand as a baseline of the present status. In this study, we developed a large-scale map of Plant Species Richness (PSR, typical indicator of biodiversity) for Young-dong and Pyung-chang provinces. Due to the accessibility of appropriate data and advance of modelling techniques, reduction of variables without deteriorating the predictive power is considered by applying Genetic algorithm. In addition, a number of Correctly Classified Instances (CCI) with 10-fold cross validation which indicates the predictive power, was carried out for evaluation. This study, as a fundamental baseline, will be beneficial in future land work as well as ecosystem restoration business or other relevant decision making agenda.

• 생명과학회지
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• 제8권2호
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• pp.216-225
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• 1998

Metal ion-induced and it’s regulatory genes were screened in virulent salmonella typhimurium UK1 and tested cross-regulation with various stresses. Using the techniqud of P22-MudJ(Km, lacZ)-directed lacZ operon fusion, LF40 cuiA::MudJ and Lf153 cuiD::MudJ which were induced by copper were selected. cuia and cuiD were determined anaerobic coper inducible and copper tolerance response gene, respectively. Also cuiA and cuiD locus were determined at 81 and 8min, respectively, on salmonella Genetic Map. The two regulators were identified as cuaR, and cudR, which controls cuiA and cuiD, respectively. cuaR, and cudR appeared as negative regulators because the expression of cuiA-lac-Z and cuiD-lacZ were increased. Copper adapted UK1 showed high resistance to H$_{2}$O$_{2}$, but cuiD did not. The product of the cudR locus was responsible for decreasing the tolerance to copper and H$_{2}$O$_{2}$. Furthemore cuiA and cuiD locus were found to be part of a regulon under the control of a trans-acting regulators, rpoS, oxyR and relA. Therefore, the results suggest CTR participate with oxidative stress on Salmonella.

• 한국시뮬레이션학회논문지
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• 제22권2호
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• pp.33-40
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• 2013

본 논문은 에이전트 기반 모델링 및 시뮬레이션을 바탕으로 한 한국군 GOP 경계시스템에 관한 연구이다. 에이전트 기반 모델링 및 시뮬레이션 기반 소프트웨어인 MANA를 이용하여 다양한 시나리오를 모델링하고 유전학적 알고리즘을 통해 침투 양상이 변화하는 적에 대해 분석하였다. 우리는 유전학적 알고리즘을 이용하여 침투하는 적의 최적화된 행동에 근사하는 값을 구하기 위해 최적화 모델을 구성하였다. 그 결과는 GOP 경계시스템에서 침투하는 적의 행동에 대한 최적화가 경계시스템의 효과성에 현저한 차이를 가져온다는 점과 침투하는 적의 아군 자산에 대한 회피 정도는 각각의 자산의 중요성을 반영한다는 점에서 두 가지 중요한 통찰력을 제공한다.

• ETRI Journal
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• 제43권3호
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• pp.436-446
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• 2021

In this paper, we propose an energy-efficient unmanned aerial vehicle (UAV) relaying network. In this network, the channels between UAVs and ground transceivers are model-free. A UAV acting as a flying relay explores better channels to assist in efficient data delivery between two ground nodes. The full-duplex relaying mode is applied for potential energy efficiency (EE) improvements. With the genetic algorithm, we manage to optimize the UAV trajectory for any arbitrary radio map scenario. Numerical results demonstrate that compared to other schemes (eg, fixed trajectory/speed policies), the proposed algorithm performs better in terms of EE. Additionally, the impact of self-interference on average EE is also investigated.

• Steel and Composite Structures
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• 제47권6호
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• pp.759-779
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• 2023

The paper proposes two hybrid metaheuristic optimization and artificial neural network (ANN) methods for the close prediction of the ultimate axial compressive capacity of concentrically loaded concrete filled double skin steel tube (CFDST) columns. Two metaheuristic optimization, namely genetic algorithm (GA) and particle swarm optimization (PSO), approaches enable the dynamic training architecture underlying an ANN model by optimizing the number and sizes of hidden layers as well as the weights and biases of the neurons, simultaneously. The former is termed as GA-ANN, and the latter as PSO-ANN. These techniques utilize the gradient-based optimization with Bayesian regularization that enhances the optimization process. The proposed GA-ANN and PSO-ANN methods construct the predictive ANNs from 125 available experimental datasets and present the superior performance over standard ANNs. Both the hybrid GA-ANN and PSO-ANN methods are encoded within a user-friendly graphical interface that can reliably map out the accurate ultimate axial compressive capacity of CFDST columns with various geometry and material parameters.

• Journal of Plant Biotechnology
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• 제42권4호
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• pp.342-349
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• 2015

키위는 세계적으로 1970년대 이후 상업화되어 최근 재배가 급속히 확대되고 있는 신종 과수이며, 국내에서도 재배와 소비량이 급격히 증가하고 있다. 키위는 자웅이주 낙엽성 덩굴 식물로 과피에 털이 있고 과육색이 다양한 특성을 가지고 있으며 배수성도 다양하나, 산업적인 품종 구성은 매우 단순하다. 독특한 식물적 특성에 기인한 진화 및 생물학적 관점은 물론 다양한 품종의 효율적 개발의 요구에 따라 최근 유전체 해석 및 활용 연구가 활발히 진행되고 있다. 키위 유전체 draft 서열과 엽록체 서열이 Illumina HiSeq 기반으로 각각 2013년과 2015년에 해독 되었으며 gene annotation 연구가 계속적으로 진행되고 있다. 과거 ESTs 기반의 전사체 분석에서 최근 RNA-seq 기반의 전사체 분석으로 전환되어 과일의 아스코르브산 생합성, 과육색 발현 및 성숙, 그리고 나무의 궤양병 저항성 관련 유전적 발현조절과 유전자 발굴 연구가 중점적으로 진행되고 있다. 전통육종의 효율을 증대하기 위한 분자표지 개발 및 유전자지도 작성에 있어서는 이전의 RFLP, RAPD, AFLP 기반의 연구에서 벗어나 NGS 기반의 유전체 및 전사체 정보의 해독에 의한 SSR 및 SNP 기반의 농업적으로 중요한 형질연관 분자마커 개발 및 고밀도 유전자지도 작성이 연구되고 있다. 그러나 국내 연구는 아직 제한적인 수준에서 진행되고 있다. 향후 키위 유전체 및 전사체 분석 연구는 가까운 장래에 실질적으로 분자육종에 적용될 것으로 전망된다.

• Journal of Microbiology and Biotechnology
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• 제15권4호
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• pp.756-766
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• 2005

The signaling mechanism underlying aburatubolactam C-induced FasL upregulation was investigated in human Jurkat T cells. After treatment with aburatubolactam C, the src-family PTKs $p56^{lck}\;and\;p59^{fyn}$, and MAP kinases ERK2 and JNK1, were activated prior to FasL upregulation; Both $p56^{lck}\;and\;p59^{fyn}$ were directly activated 2.4- and 2.2-fold, respectively, in vitro by aburatubolactam C. The aburatubolactam C-induced cellular changes, including the activation of ERK2 and INK1, and FasL upregulation, were completely prevented by the PTK inhibitor genistein. The activation of protein kinase C (PKC$\delta,\;\epsilon\;and\;\mu$ was also induced following aburatubolactam C treatment. Although the activation of $p56^{lck}$ and tyrosine phosphorylation of the cellular proteins were not blocked by the PKC inhibitor GFl09203X, the activation of ERK2 was completely abrogated, along with a detectably enhanced JNK1 activation; FasL upregulation, and apoptosis. However, the FasL upregulation and apoptosis were significantly inhibited by the PKC activator PMA, with a remarkable increase in the ERK2 activation. The cytotoxic effect of aburatubolactam C was reduced in the presence of the anti-Fas neutralizing antibody ZB-4. Although ectopic expression of Bcl-2 failed to completely block the cytotoxicity of aburatubolactam C, it was clearly suppressed. The c-Fos mRNA expression was upregulated in a biphasic manner, where the second phasic expression overlapped with the FasL upregulation. Accordingly, these results demonstrate that aburatubolactam C-induced apoptosis is exerted, at least in part, by FasL upregulation dictated by activation of the PTK ($p56^{lck}\;and\;p59^{fyn}$) /JNKI pathway, which is negatively affected by the concurrent activation of the PKC/ERK2 pathway proximal to PTK activation.

• Genomics & Informatics
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• 제1권1호
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• pp.50-54
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• 2003

Genome of an extreme thermophile, Thermus caldophilus GK24 has been analyzed to construct the genomic map. The genomic DNAs encapsulated in agarose gel were digested with SspI, EcoRI, SpeI, and HpaI restriction endonucleases, and then the resulting genomic DNA fragments were analyzed by pulsed-field gel electrophoresis. Its restriction map has been constructed by analyzing sizes of the restriction fragments obtained from both complete and partial digestions. The circular form of its genome was composed of about 1.98 Mbp and a megaplasmid. The genomic loci for the genes of xylose isomerase, thioredoxin, tRNA-16S rRNA, 23S rRNA, L5 ribosomal protein, ADP-glucose pyrophosphorylase, DNA-ligase, and Tca DNA polymerase were determined by both Southern hybridization and PCR.