• 제목/요약/키워드: Genetic identification

검색결과 1,286건 처리시간 0.038초

RAPD(Random Amplified Polymorphic DNA)법을 이용한 한약재의 판별 연구 (Identification and classification study of natural products by RAPD analysis)

  • 김대원;김도균;안선경;조동욱
    • 한국한의학연구원논문집
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    • 제3권1호
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    • pp.153-167
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    • 1997
  • Conventionally, identification and classification methods of natural products include the morphological survey and assay of chemical disposition, sing these methods, however, is not satisfying for the precise identification of natural products because they are often valiable in the compositions and morphology To standardize the natural products identification and classification, genomic DNA analysis such as RAPD, RFLP and Amp-FLP can be adopted for this purpose. In this study, various ginsengs and bear gall bladder were tested for the development of genetic identification and classification method. Varieties of ginsengs such as, P. ginseng, P. quinquefolium, P. japonicus and P. notoginseng, were genetically analyzed by RAPD. Also, DNA isolated from Bear blood and gall bladder, Ursus thibetanus, Ursus americanus and Ursus arctos, were analyzed by the same method. The results demonstrated that the identification and classification of bear gall bladder and various ginsengs were possible by RAPD analysis. Therefore, this method was thought to be used as a additional method for the identification and classification of other natural products.

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Fuzzy Model Identification for Time Series System Using Wavelet Transform and Genetic DNA-Code

  • Lee, Yeun-Woo;Kim, Jung-Chan;Joo, Young-Hoon
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 2003년도 ISIS 2003
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    • pp.322-325
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    • 2003
  • In this paper, we propose n new fuzzy model identification of time series system using wavelet transform and genetic DNA code. Generally, it is well known that the DNA coding method is more diverse in the knowledge expression and better in the optimization performance than the genetic algorithm (GA) because it can encode more plentiful genetic information based on the biological DNA. The proposed method can construct a fuzzy model using the wavelet transform, in which the coefficients are identified by the DNA coding method. Thus, we can effectively get the fuzzy model of the nonlinear system by using the advantages of both wavelet transform and DNA coding method. In order to demonstrate the superiority of the proposed method, it is compared with modeling method using the conventional GA.

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Genetic Hearing Loss and Gene Therapy

  • Carpena, Nathanial T;Lee, Min Young
    • Genomics & Informatics
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    • 제16권4호
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    • pp.20.1-20.20
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    • 2018
  • Genetic hearing loss crosses almost all the categories of hearing loss which includes the following: conductive, sensory, and neural; syndromic and nonsyndromic; congenital, progressive, and adult onset; high-frequency, low-frequency, or mixed frequency; mild or profound; and recessive, dominant, or sex-linked. Genes play a role in almost half of all cases of hearing loss but effective treatment options are very limited. Genetic hearing loss is considered to be extremely genetically heterogeneous. The advancements in genomics have been instrumental to the identification of more than 6,000 causative variants in more than 150 genes causing hearing loss. Identification of genes for hearing impairment provides an increased insight into the normal development and function of cells in the auditory system. These defective genes will ultimately be important therapeutic targets. However, the auditory system is extremely complex which requires tremendous advances in gene therapy including gene vectors, routes of administration, and therapeutic approaches. This review summarizes and discusses recent advances in elucidating the genomics of genetic hearing loss and technologies aimed at developing a gene therapy that may become a treatment option for in the near future.

유전알고리즘과 러프집합을 이용한 계층적 식별 규칙을 갖는 가스 식별 시스템의 설계 (Design of Gas Identification System with Hierarchically Identifiable Rule base using GAS and Rough Sets)

  • 조해파;방영근;이철희
    • 산업기술연구
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    • 제31권B호
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    • pp.37-43
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    • 2011
  • In pattern analysis, dimensionality reduction and reasonable identification rule generation are very important parts. This paper performed effectively the dimensionality reduction by grouping the sensors of which the measured patterns are similar each other, where genetic algorithms were used for combination optimization. To identify the gas type, this paper constructed the hierarchically identifiable rule base with two frames by using rough set theory. The first frame is to accept measurement characteristics of each sensor and the other one is to reflect the identification patterns of each group. Thus, the proposed methods was able to accomplish effectively dimensionality reduction as well as accurate gas identification. In simulation, this paper demonstrated the effectiveness of the proposed methods by identifying five types of gases.

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최적화기법에 의한 베어링 동특성 계수의 규명 (Identification of Bearing Dynamic Coefficients Using Optimization Techniques)

  • 김용한;양보석;안영공;김영찬
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2003년도 춘계학술대회논문집
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    • pp.520-525
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    • 2003
  • The determination of unknown parameters in rotating machinery is a difficult task and optimization techniques represent an alternative technique for parameter identification. The Simulated Annealing(SA) and Genetic Algorithm(GA) are powerful global optimization algorithm. This paper proposes new hybrid algorithm which combined GA with SA and local search algorithm for the purpose of parameter identification. Numerical examples are also presented to verify the efficiency of proposed algorithm. And, this paper presents the general methodology based on hybrid algorithm to identify unknown bearing parameters of flexible rotors using measured unbalance responses. Numerical examples are used to ilustrate the methodology used, which is then validated experimentally.

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네트워크형 이산 시스템의 동정에 관하여 (On Identification of Discrete System Expressed by Network Model)

  • 석상문;강기중;이철영
    • 한국항만학회지
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    • 제14권2호
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    • pp.155-163
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    • 2000
  • A discrete system has interpreted by using the network model, and PERT network is one of these methods. For the purpose of analysing the real system, it is necessary to measure the parameter of the real system. And system identification problem is to assume the parameter of a real system when we get to know the system model, the input data and output data. System identification method has been only developed to a system of which a structure has expressed a differential equation or a polynomial expression. But it has been scarcely developed yet in that case of network model. The aim of this paper is to examine a changes when new system is introduced to the present system. The changes are as follows : how the present system will be changed, when the changes will be happened. In this paper, genetic algorithm is used to assume the parameter.

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네트워크형 이산 시스템의 동정에 관하여 (On Identification of discrete system expressed by Network Model)

  • 석상문;강기중;이철영
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 1999년도 추계학술대회논문집
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    • pp.101-108
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    • 1999
  • A discrete system has interpreted by using the network model, and PERT network is one of these methods. For the purpose of analysing the real system. it is necessary to measure the parameter of the real system. And system identification problem is to assume the parameter of a real system when we get to know the system model, the input data and output data. System identification method has been only developed to a system of which a structure has expressed a differential equation or a polynomial expression. But it has been scarcely developed yet in that case of network model. The aim of this paper is to examine a changes when new system isn introduced to the present system, The changes are as follows: how the present system will be changed, when the changes will be happened. In this paper, genetic algorithm is used to assume the parameter.