• 한국항해항만학회지
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• 제33권9호
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• pp.635-644
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• 2009

The optimum design of power yacht belongs to the nonlinear constrained optimization problems. The determination of scantlings for the bow structure is a very important issue with in the whole structural design process. The derived design results are obtained by the use of real-coded micro-genetic algorithm including evaluation from Lloyd's Register small craft guideline, so that the nominal limiting stress requirement can be satisfied. In this study, the minimum volume design of bow structure on the power yacht was carried out based on the finite element analysis. The target model for optimum design and local structural analysis is the bow structure of a power yacht. The volume of bow structure and the main dimensions of structural members are chosen as an objective function and design variable, respectively. During optimization procedure, finite element analysis was performed to determine the constraint parameters at each iteration step of the optimization loop. optimization results were compared with a pre-existing design and it was possible to reduce approximately 19 percents of the total steel volume of bow structure from the previous design for the power yacht.

• 대한전기학회논문지:전력기술부문A
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• 제48권11호
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• pp.1382-1387
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• 1999

This paper presents an optimal fuzzy power system stabilizer to damp out low frequency oscillation. So far fuzzy controllers have been applied to power system stabilizing controllers due to its excellent properties on the nonlinear systems. But the design process of fuzzy logic power system stabilizer requires empirical and heuristic knowledge of human experts as well as many trial-and-errors in general. This paper presents and optimal design method of the fuzzy logic stabilizer using the genetic algorithm. Non-symmetric membership functions are optimally tuned over an evaluation function. The present inputs of fuzzy stabilizer are torque angle error and the change of torque angle error without loss of generality. The coding method used in this paper is concatenated binary mapping. Each linguistic fuzzy variable, defined as the peak of a membership function, is assigned by the mapping from a minimum value to a maximum value using eight bits. The tournament selection and the elitism are used to keep the worthy individuals in the next generation. The proposed system is applied to the one-machine infinite-bus model of a power system, and the results showed a promising possibility.

• 한국지능시스템학회논문지
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• 제20권2호
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• pp.234-242
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• 2010

본 논문은 가장 중요한 자료구조 중 하나인 그래프를 효과적으로 시각화하는 방법에 관해 다룬다. 그래프 시각화의 목적은 원래의 그래프 구조를 이해하기 쉽게 잘 표현하는 것이지만 일반적으로 그래프의 크기가 커짐에 따라 교차하는 간선의 수가 급격히 증가하여 각 정점 간의 관계를 눈으로 확인하기 쉽지 않게 된다. 우리는 이 문제에 대한 새로운 해결 방법을 제시한다. 기존의 연구들이 대부분 간선의 교차 수를 최소화하는 조건만 고려하였던 것을 벗어나 본 논문에서는 간선 교차 최소화와 더불어 정점 간의 거리를 보존하는 것을 동시에 고려하여 원래의 그래프 구조를 최대한 잘 표현하고자 하였다. 이를 위하여 본 논문에서는 이 두 목적 값의 가중치 합으로 각 해를 평가하는 유전 알고리즘을 설계하여 시각화에 적용한다. 제안한 시각화 방법이 새로운 목적에 맞게 그래프를 잘 시각화할 수 있음을 실험을 통해 입증할 수 있었다.

• 조명전기설비학회논문지
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• 제20권6호
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• pp.81-86
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• 2006

회로 전송선 배선 시 신호선은 직선의 형태와 방향을 바꾸기 위한 구부러지는 형태를 가진다. 차동 신호선의 정확한 등가회로는 이러한 전송선 구조의 시 공간 영역에서의 신호적 특성과 인접 신호선들 간의 영향을 평가할 수 있게 해준다. 이를 위해 기존의 몇 몇 CAD Tool들이 등가 회로 모델과 그 파라미터 값들을 추출 해주기도 하지만, 이는 큰 연산량과 시간을 요구한다. 본 논문에서는 구부러진 차동 신호선의 등가회로를 모델링하기 위해 기본적 모델인 RLC-모델의 파라미터 값을 유전 알고리듬을 이용하여 추출하는 방법을 제시한다. 본 방법에 의해 더욱 빠르게 물리적 구조를 갖는 차동 신호선의 등가회로를 모델링 할 수 있다.

• Biomolecules & Therapeutics
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• 제25권2호
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• pp.165-170
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• 2017

Cordyceps bassiana is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. This mushroom has recently demonstrated to have an ability to reduce 2,4-dinitrofluorobenzene-induced atopic dermatitis symptoms in NC/Nga mice. In this study, we further examined phytochemical properties of this mushroom by column chromatography and HPLC analysis. By chromatographic separation and spectroscopic analysis, 8 compounds, such as 1,9-dimethylguanine (1), adenosine (2), uridine (3), nicotinamide (4), 3-methyluracil (5), 1,7-dimethylxanthine (6), nudifloric acid (7), and mannitol (8) were identified from 6 different fractions and 4 more subfractions. Through evaluation of their anti-inflammatory activities using reporter gene assay and mRNA analysis, compound 1 was found to block luciferase activity induced by $NF-{\kappa}B$ and AP-1, suppress the mRNA levels of cyclooxygenase (COX)-2 and tumor necrosis factor $(TNF)-{\alpha}$. Therefore, our data strongly suggests that compound 1 acts as one of major principles in Cordyceps bassiana with anti-inflammatory and anti-atopic dermatitis activities.

• Earthquakes and Structures
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• 제13권4호
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• pp.397-407
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• 2017

With the growing demand for metallic dampers in engineering practice, it is urgent to establish a reasonable approach to evaluating the mechanical performance of metallic dampers under seismic excitations. This paper introduces an effective method for parameter identification of the modified Bouc-Wen model and its application to evaluating the fatigue performance of metallic dampers (MDs). The modified Bouc-Wen model which eliminates the redundant parameter is used to describe the hysteresis behavior of MDs. Relations between the parameters of the modified Bouc-Wen model and the mechanical performance parameters of MDs are studied first. A modified Genetic Algorithm using real-integer hybrid coding with relative fitness as well as adaptive crossover and mutation rates (called RFAGA) is then proposed to identify the parameters of the modified Bouc-Wen model. A reliable approach to evaluating the fatigue performance of the MDs with respect to the Chinese Code for Seismic Design of Buildings (GB 50011-2010) is finally proposed based on the research results. Experimental data are employed to demonstrate the process and verify the effectiveness of the proposed approach. It is shown that the RFAGA is able to converge quickly in the identification process, and the simulation curves based on the identification results fit well with the experimental hysteresis curves. Furthermore, the proposed approach is shown to be a useful tool for evaluating the fatigue performance of MDs with respect to the Chinese Code for Seismic Design of Buildings (GB 50011-2010).

• Journal of Forest and Environmental Science
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• 제35권2호
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• pp.90-101
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• 2019

Biodiversity refers to the total number and variation among species of flora and fauna of an area. Due to tremendous biotic especially anthropogenic pressure these natural resources are being vanishing. In present study genetic diversity among accessions of Thamnocalamus spathiflorus was evaluated. A total of 51 vegetative characters and 42 primers (10-mer) were screened. Out of 42 screened primers, 28 polymorphic primers were selected for further analysis. A total of 263 bands were recorded as polymorphic whereas 48 bands were monomorphic. The resolving power (Rp) of 28 Randomly Amplified Polymorphic DNA (RAPD) primers ranged from 4.6 (OPE08) to 17.6 (OPA11). The polymorphic information content (PIC) value ranged from 0.21 (OPAH09) to 0.44 (OPG02). The result revealed high degree of genetic relatedness (56 to 80%). Cluster analysis revealed two major clusters both for morphology as well as RAPD. Unlike morphological characterization, the accession (D5) from Bahli, Rampur, Shimla (H.P.) was clustered separately from the others in RAPD cluster analysis. Accessions with closed locality grouped together through RAPD marker system however analogy was recorded for morphological traits. The study conducted reflects the utility of RAPD technique for species identification and phylogenetic studies in bamboo for conducting bamboo breeding program.

• Journal of Genetic Medicine
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• 제17권2호
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• pp.102-107
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• 2020

We report the case of an infant with a 4q35.1 deletion with 10p duplication. This mutation is rarely reported in the literature and has been found to have variable clinical findings, often including developmental delay. In this case, the condition was detected by chromosomal microarray analysis after initial manifestation of a feeding problem and developmental delay. Minor dysmorphic features with abnormal neurological examination led to further evaluation. The father's chromosome complement was 46, XY, t(4;10)(q35;p12.2). Parental balanced translocation can go unrecognized, because affected individuals are often phenotypically healthy until they have fertility issues such as recurrent miscarriages or children with severe congenital disorders. Genetic diagnoses help to establish a clear family genetic background that permits the development of clear treatment strategies. Prenatal counseling can also help to understand the possible risks associated with pregnancy or future child planning.

• 대한두개안면성형외과학회지
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• 제24권4호
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• pp.145-158
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• 2023

Vascular anomalies encompass a variety of malformations and tumors that can result in severe morbidity and mortality in both adults and children. Advances have been made in the classification and diagnosis of these anomalies, with the International Society for the Study of Vascular Anomalies establishing a widely recognized classification system. In recent years, notable progress has been made in genetic testing and imaging techniques, enhancing our ability to diagnose these conditions. The increasing sophistication of genetic testing has facilitated the identification of specific genetic mutations that help treatment decisions. Furthermore, imaging techniques such as magnetic resonance imaging and computed tomography have greatly improved our capacity to visualize and detect vascular abnormalities, enabling more accurate diagnoses. When considering reconstructive surgery for facial vascular anomalies, it is important to consider both functional and cosmetic results of the procedure. Therefore, a comprehensive multidisciplinary approach involving specialists from dermatology, radiology, and genetics is often required to ensure effective management of these conditions. Overall, the treatment approach for facial vascular anomalies depends on the type, size, location, and severity of the anomaly. A thorough evaluation by a team of specialists can determine the most appropriate and effective treatment plan.

• Asian-Australasian Journal of Animal Sciences
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• 제11권5호
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• pp.470-474
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• 1998

Data on the first lactation performance traits of $F_1$, $F_2$ and $F_3$ crosses covering the period from 1972 to 1995 of a total of 803 dairy cows of three genetic grades maintained at Livestock Production Research Farm, Indian Veterinary Research Institute, Izatnagar were analysed. Three genetic grades were 1/2 Friesian + 1/2 Hariana (FH), 1/2 Friesian + 1/4 Brown Swiss and 1/4 Hariana (FBH) and 1/2 Friesian+ 1/4 Jersey + 1/4 Hariana (FJH). Age at first calving increased by 7% and 8% in $F_2$ and $F_3$, respectively, over the $F_1$ in FH. The reduction in age at first calving at $F_2$ and $F_3$ levels by 2-7% over the $F_1$ was observed in FBH and FJH. The lactation milk yield of $F_1$, $F_2$ and $F_3$ crosses was $1,943{\pm}100.3$, $2202{\pm}120.5$ and $1,925{\pm}123.2kg$ in FH; $2,014{\pm}76.7$, $2,264{\pm}91.5$ and $2,096{\pm}123.9kg$ in FBH and $2,005{\pm}87.0$, $2,414{\pm}94.4$ and $2,093{\pm}121.1kg$ in FJH, respectively. The lactation milk yield improved by 12-20% in $F_2$ crosses in various genetic grades. The performance of $F_1$ was, however, maintained in FH $F_3$ crosses, it improved by 4% in FBH and FJH $F_3$ crosses. The lactation lengths and calving intervals were nearly the same for $F_1$, $F_2$ and $F_3$ crosses in FH while lactation lengths and calving intervals were reduced by 3-11% in $F_2$ and $F_3$ crosses in FBH and FJH genetic grades. The milk yield/day of lactation length and milk yield/day of calving interval increased by 16-35% in $F_2$ and 2-14% in $F_3$ over the $F_1$ in various genetic grades. It is recommended that a sufficiently large effective population size of these three genetic grades be maintained by inter se matings and rigorous selection of sires so for developing a genetic base population for new breed development.