• 제목/요약/키워드: Genetic evaluation

검색결과 886건 처리시간 0.024초

A Study on the Urinary Metabolite by PAHs and Genetic Susceptibility Markers

  • Chung, Young-Hee;Kim, Dae-Seon;Kang, Tack-Shin
    • 한국환경보건학회:학술대회논문집
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    • 한국환경보건학회 2005년도 Proceedings of KSEH.Minamata Forum
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    • pp.115-117
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    • 2005
  • In this study, the methods were developed to measure polycyclic aromatic hydrocarbons(PAHs) in the air, metabolites of pyrene and benzo(a)pyrene via human urine, genetic polymorphisms in human buccal cell for evaluation of the health effects about environmental pollution. We have also performed a preliminary molecular epidemiology study on residents in the metropolitan area and workers in workplace for these method applications.

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Evaluation of Genetic Diversity among Korean Wild Codonopsis lanceolata by Using RAPD

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    • 한국자원식물학회지
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    • 제10권3호
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    • pp.258-264
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    • 1997
  • The introduction of molecular biology methodologies to plant improvement programs offers an invaluable opportunity for extensive germplasm characterization. We have applied the developed technique of random amplification of polymorphic DNA(RAPD)to the analysis of evaluating genetic diversity among Korean wild Codonopsis lanceolata. A total of 340 polymorpic hands were gernerated on agarose- and polyacrylamide-gel by 19 primers of abitrary sequence. grouped by cluster analysis using sample matching coefficients of similarity. Among of the samples. the minimum genetic distance value was obtained between sample no. 1(Girisan) and no. 2(Girisan), and the largest value between sample no. 11(Sulaksan) and no. 17(Sulaksan).In separate cluster dendrograms based on agareose - and polyacryamide-gel. some differences were observed; In the case of agarose gel,41 samples could be devided into 7 groups at below about 0.44 level of distance. However they were divided into 6 gourps at below about 0.40 level of distance in the case of polyacrylamide gel. These results showed that polymophic data in agrose were not grouped to wild plant selected from each mountainous district except for wild plants selected from Sulaksan and Chiaksan. We believe that polyacrylamide-RAPD is a superior method for detecting DNA polymorphism compared to agarose-RAPD method.

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배전계통 최적기본신뢰도 지수 평가를 위한 유전자 알고리즘의 적용 (Assessment of the optimal basic reliability in distribution system using genetic algorithm)

  • 김재철;한성호;이보호;이욱;장정태
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1995년도 추계학술대회 논문집 학회본부
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    • pp.64-66
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    • 1995
  • This paper presents a new approach to evaluate optimal basic reliability indices of electric distribution systems using genetic algorithm. The use of optimal reliability evaluation is an important aspect of distribution system planning and operation to determine adequacy reliability level of each area. In this paper, the reliability model is based on the analytical method, connecting component failure to load point outage in each section. The proposed method applies genetic algorithm to calculate the optimal values of basic reliability indices, ie. failure rate and repair time, for a load point in the power distribution system, subject to minimizing interruption cost. Test results for the model system are reported in the paper compared with a direct optimization method(gradient projection).

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Evaluation of Genetic Diversity among the Genus Viola by RAPD Markers

  • Oh, Boung-Jun;Ko, Moon-Kyung;Lee, Cheol-Hee
    • 한국자원식물학회지
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    • 제19권6호
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    • pp.716-720
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    • 2006
  • The genetic diversity among the genus Viola was evaluated using the random amplified polymorphic DNA (RAPD) method. A total of 142 distinct amplification fragments by 18 random primers were scored to perform the cluster analysis with UPGMA. Viola species from the subsection Patellares were clustered into group I to IV. The groups from I to IV were consistent with its morphological taxonomy, series Pinnatae, Chinensis, Variegatae, and Patellares in the subsection Patellares, respectively. Even though V. albida and V. albida var. takahasii were classified in Chinensis, they were assigned into group I. The cluster analysis separated other subsections from Patellares in the section Nomimium. Interestingly, V. verecunda and V. grypoceras in subsections Biobatae and Trigonocarpae, respectively, were clustered into group C with a high similarity coefficient. Therefore, RAPD analysis can be used for providing an alternative classification system to identify genotypes and morphological characters of Viola species.

구조최적화를 위한 병렬유전자 알고리즘 (Parallel Genetic Algorithm for Structural Optimization on a Cluster of Personal Computers)

  • 이준호;박효선
    • 한국전산구조공학회:학술대회논문집
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    • 한국전산구조공학회 2000년도 가을 학술발표회논문집
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    • pp.40-47
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    • 2000
  • One of the drawbacks of GA-based structural optimization is that the fitness evaluation of a population of hundreds of individuals requiring hundreds of structural analyses at each CA generation is computational too expensive. Therefore, a parallel genetic algorithm is developed for structural optimization on a cluster of personal computers in this paper. Based on the parallel genetic algorithm, a population at every generation is partitioned into a number of sub-populations equal to the number of slave computers. Parallelism is exploited at sub-population level by allocationg each sub-population to a slave computer. Thus, fitness of a population at each generation can be concurrently evaluated on a cluster of personal computers. For implementation of the algorithm a virtual distributed computing system in a collection of personal computers connected via a 100 Mb/s Ethernet LAN. The algorithm is applied to the minimum weight design of a steel structure. The results show that the computational time requied for serial GA-based structural optimization process is drastically reduced.

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Application of multi objective genetic algorithm in ship hull optimization

  • Guha, Amitava;Falzaranoa, Jeffrey
    • Ocean Systems Engineering
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    • 제5권2호
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    • pp.91-107
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    • 2015
  • Ship hull optimization is categorized as a bound, multi variable, multi objective problem with nonlinear constraints. In such analysis, where the objective function representing the performance of the ship generally requires computationally involved hydrodynamic interaction evaluation methods, the objective functions are not smooth. Hence, the evolutionary techniques to attain the optimum hull forms is considered as the most practical strategy. In this study, a parametric ship hull form represented by B-Spline curves is optimized for multiple performance criteria using Genetic Algorithm. The methodology applied to automate the hull form generation, selection of optimization solvers and hydrodynamic parameter calculation for objective function and constraint definition are discussed here.

퍼지선호관계 순서화 문제와 유전자 알고리즘 기반 해법 (A Sequencing Problem with Fuzzy Preference Relation and its Genetic Algorithm-based Solution)

  • 이건명;손봉기
    • 한국지능시스템학회논문지
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    • 제14권1호
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    • pp.69-74
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    • 2004
  • A sequencing problem is to find an ordered sequence of some entities which maximizes (or minimize) the domain specific objective function. As some typical examples of sequencing problems, there are traveling salesman problem, job shop scheduling, flow shop scheduling, and so on. This paper introduces a new type of sequencing problems, named a sequencing problem with fuzzy preference relation, where a fuzzy preference relation is provided for the evaluation of the quality of sequences. It presents how such a problem can be formulated in terms of objective function. It also proposes a genetic algorithm applicable to such a sequencing problem.

A Genetic Algorithm Approach to the Frequency Assignment Problem on VHF Network of SPIDER System

  • Kwon, O-Jeong
    • 한국국방경영분석학회지
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    • 제26권1호
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    • pp.56-69
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    • 2000
  • A frequency assignment problem on time division duplex system is considered. Republic of Korea Army (ROKA) has been establishing an infrastructure of tactical communication (SPIDER) system for next generation and it will be a core network structure of system. VHF system is the backbone network of SPIDER, that performs transmission of data such as voice, text and images. So, it is a significant problem finding the frequency assignment with no interference under very restricted resource environment. With a given arbitrary configuration of communications network, we find a feasible solution that guarantees communication without interference between sites and relay stations. We formulate a frequency assignment problem as an Integer Programming model, which has NP-hard complexity. To find the assignment results within a reasonable time, we take a genetic algorithm approach which represents the solution structure with available frequency order, and develop a genetic operation strategies. Computational result shows that the network configuration of SPIDER can be solved efficiently within a very short time.

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A non-destructive method for elliptical cracks identification in shafts based on wave propagation signals and genetic algorithms

  • Munoz-Abella, Belen;Rubio, Lourdes;Rubio, Patricia
    • Smart Structures and Systems
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    • 제10권1호
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    • pp.47-65
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    • 2012
  • The presence of crack-like defects in mechanical and structural elements produces failures during their service life that in some cases can be catastrophic. So, the early detection of the fatigue cracks is particularly important because they grow rapidly, with a propagation velocity that increases exponentially, and may lead to long out-of-service periods, heavy damages of machines and severe economic consequences. In this work, a non-destructive method for the detection and identification of elliptical cracks in shafts based on stress wave propagation is proposed. The propagation of a stress wave in a cracked shaft has been numerically analyzed and numerical results have been used to detect and identify the crack through the genetic algorithm optimization method. The results obtained in this work allow the development of an on-line method for damage detection and identification for cracked shaft-like components using an easy and portable dynamic testing device.

Somatic Cells Count and Its Genetic Association with Milk Yield in Dairy Cattle Raised under Thai Tropical Environmental Conditions

  • Jattawa, D.;Koonawootrittriron, S.;Elzo, M.A.;Suwanasopee, T.
    • Asian-Australasian Journal of Animal Sciences
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    • 제25권9호
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    • pp.1216-1222
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    • 2012
  • Somatic cells count (SCC), milk yield (MY) and pedigree information of 2,791 first lactation cows that calved between 1990 and 2010 on 259 Thai farms were used to estimate genetic parameters and trends for SCC and its genetic association with MY. The SCC were log-transformed (lnSCC) to make them normally distributed. An average information-restricted maximum likelihood procedure was used to estimate variance components. A bivariate animal model that considered herd-yr-season, calving age, and regression additive genetic group as fixed effects, and animal and residual as random effects was used for genetic evaluation. Heritability estimates were 0.12 (SE = 0.19) for lnSCC, and 0.31 (SE = 0.06) for MY. The genetic correlation estimate between lnSCC and MY was 0.26 (SE = 0.59). Mean yearly estimated breeding values during the last 20 years increased for SCC (49.02 cells/ml/yr, SE = 26.81 cells/ml/yr; p = 0.08), but not for MY (0.37 kg/yr, SE = 0.87 kg/yr; p = 0.68). Sire average breeding values for SCC and MY were higher than those of cows and dams (p<0.01). Heritability estimates for lnSCC and MY and their low but positive genetic correlation suggested that selection for low SCC may be feasible in this population as it is in other populations of dairy cows. Thus, selection for high MY and low SCC should be encouraged in Thai dairy improvement programs to increase profitability by improving both cow health and milk yield.