• Journal of Navigation and Port Research
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• v.33 no.9
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• pp.635-644
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• 2009

The optimum design of power yacht belongs to the nonlinear constrained optimization problems. The determination of scantlings for the bow structure is a very important issue with in the whole structural design process. The derived design results are obtained by the use of real-coded micro-genetic algorithm including evaluation from Lloyd's Register small craft guideline, so that the nominal limiting stress requirement can be satisfied. In this study, the minimum volume design of bow structure on the power yacht was carried out based on the finite element analysis. The target model for optimum design and local structural analysis is the bow structure of a power yacht. The volume of bow structure and the main dimensions of structural members are chosen as an objective function and design variable, respectively. During optimization procedure, finite element analysis was performed to determine the constraint parameters at each iteration step of the optimization loop. optimization results were compared with a pre-existing design and it was possible to reduce approximately 19 percents of the total steel volume of bow structure from the previous design for the power yacht.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.48 no.11
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• pp.1382-1387
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• 1999

This paper presents an optimal fuzzy power system stabilizer to damp out low frequency oscillation. So far fuzzy controllers have been applied to power system stabilizing controllers due to its excellent properties on the nonlinear systems. But the design process of fuzzy logic power system stabilizer requires empirical and heuristic knowledge of human experts as well as many trial-and-errors in general. This paper presents and optimal design method of the fuzzy logic stabilizer using the genetic algorithm. Non-symmetric membership functions are optimally tuned over an evaluation function. The present inputs of fuzzy stabilizer are torque angle error and the change of torque angle error without loss of generality. The coding method used in this paper is concatenated binary mapping. Each linguistic fuzzy variable, defined as the peak of a membership function, is assigned by the mapping from a minimum value to a maximum value using eight bits. The tournament selection and the elitism are used to keep the worthy individuals in the next generation. The proposed system is applied to the one-machine infinite-bus model of a power system, and the results showed a promising possibility.

• Journal of the Korean Institute of Intelligent Systems
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• v.20 no.2
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• pp.234-242
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• 2010

In this paper, we deal with the visualization of graphs, which are one of the most important data structures. As the size of a graph increases, it becomes more difficult to check the graph visually because of the increase of edge intersections. We propose a new method of overcoming such problem. Most of previous studies considered only the minimization of edge intersections, but we additionally pursue to preserve distances between vertices. We present a novel genetic algorithm using an evaluation function based on a weighted sum of two objectives. Our experiments could show effective visualization results.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.20 no.6
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• pp.81-86
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• 2006

Routing signal lines in PCB, line shapes would be straight or bent. time-domain and frequency-domain evaluation of the signal property and interference are archived by precise Modeling of differential signal line. Some of CAD tools can extract equivalent circuit model parameters. but it takes a long time and heavy loads. This paper introduces a basic RLC equivalent circuit model parameter extraction technique for bent differential structures using genetic algorithm by this technique, we can model equivalent circuit of bent differential structures more faster.

• Biomolecules & Therapeutics
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• v.25 no.2
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• pp.165-170
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• 2017

Cordyceps bassiana is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. This mushroom has recently demonstrated to have an ability to reduce 2,4-dinitrofluorobenzene-induced atopic dermatitis symptoms in NC/Nga mice. In this study, we further examined phytochemical properties of this mushroom by column chromatography and HPLC analysis. By chromatographic separation and spectroscopic analysis, 8 compounds, such as 1,9-dimethylguanine (1), adenosine (2), uridine (3), nicotinamide (4), 3-methyluracil (5), 1,7-dimethylxanthine (6), nudifloric acid (7), and mannitol (8) were identified from 6 different fractions and 4 more subfractions. Through evaluation of their anti-inflammatory activities using reporter gene assay and mRNA analysis, compound 1 was found to block luciferase activity induced by $NF-{\kappa}B$ and AP-1, suppress the mRNA levels of cyclooxygenase (COX)-2 and tumor necrosis factor $(TNF)-{\alpha}$. Therefore, our data strongly suggests that compound 1 acts as one of major principles in Cordyceps bassiana with anti-inflammatory and anti-atopic dermatitis activities.

• Earthquakes and Structures
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• v.13 no.4
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• pp.397-407
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• 2017

With the growing demand for metallic dampers in engineering practice, it is urgent to establish a reasonable approach to evaluating the mechanical performance of metallic dampers under seismic excitations. This paper introduces an effective method for parameter identification of the modified Bouc-Wen model and its application to evaluating the fatigue performance of metallic dampers (MDs). The modified Bouc-Wen model which eliminates the redundant parameter is used to describe the hysteresis behavior of MDs. Relations between the parameters of the modified Bouc-Wen model and the mechanical performance parameters of MDs are studied first. A modified Genetic Algorithm using real-integer hybrid coding with relative fitness as well as adaptive crossover and mutation rates (called RFAGA) is then proposed to identify the parameters of the modified Bouc-Wen model. A reliable approach to evaluating the fatigue performance of the MDs with respect to the Chinese Code for Seismic Design of Buildings (GB 50011-2010) is finally proposed based on the research results. Experimental data are employed to demonstrate the process and verify the effectiveness of the proposed approach. It is shown that the RFAGA is able to converge quickly in the identification process, and the simulation curves based on the identification results fit well with the experimental hysteresis curves. Furthermore, the proposed approach is shown to be a useful tool for evaluating the fatigue performance of MDs with respect to the Chinese Code for Seismic Design of Buildings (GB 50011-2010).

• Journal of Forest and Environmental Science
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• v.35 no.2
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• pp.90-101
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• 2019

Biodiversity refers to the total number and variation among species of flora and fauna of an area. Due to tremendous biotic especially anthropogenic pressure these natural resources are being vanishing. In present study genetic diversity among accessions of Thamnocalamus spathiflorus was evaluated. A total of 51 vegetative characters and 42 primers (10-mer) were screened. Out of 42 screened primers, 28 polymorphic primers were selected for further analysis. A total of 263 bands were recorded as polymorphic whereas 48 bands were monomorphic. The resolving power (Rp) of 28 Randomly Amplified Polymorphic DNA (RAPD) primers ranged from 4.6 (OPE08) to 17.6 (OPA11). The polymorphic information content (PIC) value ranged from 0.21 (OPAH09) to 0.44 (OPG02). The result revealed high degree of genetic relatedness (56 to 80%). Cluster analysis revealed two major clusters both for morphology as well as RAPD. Unlike morphological characterization, the accession (D5) from Bahli, Rampur, Shimla (H.P.) was clustered separately from the others in RAPD cluster analysis. Accessions with closed locality grouped together through RAPD marker system however analogy was recorded for morphological traits. The study conducted reflects the utility of RAPD technique for species identification and phylogenetic studies in bamboo for conducting bamboo breeding program.

• Journal of Genetic Medicine
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• v.17 no.2
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• pp.102-107
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• 2020

We report the case of an infant with a 4q35.1 deletion with 10p duplication. This mutation is rarely reported in the literature and has been found to have variable clinical findings, often including developmental delay. In this case, the condition was detected by chromosomal microarray analysis after initial manifestation of a feeding problem and developmental delay. Minor dysmorphic features with abnormal neurological examination led to further evaluation. The father's chromosome complement was 46, XY, t(4;10)(q35;p12.2). Parental balanced translocation can go unrecognized, because affected individuals are often phenotypically healthy until they have fertility issues such as recurrent miscarriages or children with severe congenital disorders. Genetic diagnoses help to establish a clear family genetic background that permits the development of clear treatment strategies. Prenatal counseling can also help to understand the possible risks associated with pregnancy or future child planning.

• Archives of Craniofacial Surgery
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• v.24 no.4
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• pp.145-158
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• 2023

Vascular anomalies encompass a variety of malformations and tumors that can result in severe morbidity and mortality in both adults and children. Advances have been made in the classification and diagnosis of these anomalies, with the International Society for the Study of Vascular Anomalies establishing a widely recognized classification system. In recent years, notable progress has been made in genetic testing and imaging techniques, enhancing our ability to diagnose these conditions. The increasing sophistication of genetic testing has facilitated the identification of specific genetic mutations that help treatment decisions. Furthermore, imaging techniques such as magnetic resonance imaging and computed tomography have greatly improved our capacity to visualize and detect vascular abnormalities, enabling more accurate diagnoses. When considering reconstructive surgery for facial vascular anomalies, it is important to consider both functional and cosmetic results of the procedure. Therefore, a comprehensive multidisciplinary approach involving specialists from dermatology, radiology, and genetics is often required to ensure effective management of these conditions. Overall, the treatment approach for facial vascular anomalies depends on the type, size, location, and severity of the anomaly. A thorough evaluation by a team of specialists can determine the most appropriate and effective treatment plan.

• Asian-Australasian Journal of Animal Sciences
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• v.11 no.5
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• pp.470-474
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• 1998

Data on the first lactation performance traits of $F_1$, $F_2$ and $F_3$ crosses covering the period from 1972 to 1995 of a total of 803 dairy cows of three genetic grades maintained at Livestock Production Research Farm, Indian Veterinary Research Institute, Izatnagar were analysed. Three genetic grades were 1/2 Friesian + 1/2 Hariana (FH), 1/2 Friesian + 1/4 Brown Swiss and 1/4 Hariana (FBH) and 1/2 Friesian+ 1/4 Jersey + 1/4 Hariana (FJH). Age at first calving increased by 7% and 8% in $F_2$ and $F_3$, respectively, over the $F_1$ in FH. The reduction in age at first calving at $F_2$ and $F_3$ levels by 2-7% over the $F_1$ was observed in FBH and FJH. The lactation milk yield of $F_1$, $F_2$ and $F_3$ crosses was $1,943{\pm}100.3$, $2202{\pm}120.5$ and $1,925{\pm}123.2kg$ in FH; $2,014{\pm}76.7$, $2,264{\pm}91.5$ and $2,096{\pm}123.9kg$ in FBH and $2,005{\pm}87.0$, $2,414{\pm}94.4$ and $2,093{\pm}121.1kg$ in FJH, respectively. The lactation milk yield improved by 12-20% in $F_2$ crosses in various genetic grades. The performance of $F_1$ was, however, maintained in FH $F_3$ crosses, it improved by 4% in FBH and FJH $F_3$ crosses. The lactation lengths and calving intervals were nearly the same for $F_1$, $F_2$ and $F_3$ crosses in FH while lactation lengths and calving intervals were reduced by 3-11% in $F_2$ and $F_3$ crosses in FBH and FJH genetic grades. The milk yield/day of lactation length and milk yield/day of calving interval increased by 16-35% in $F_2$ and 2-14% in $F_3$ over the $F_1$ in various genetic grades. It is recommended that a sufficiently large effective population size of these three genetic grades be maintained by inter se matings and rigorous selection of sires so for developing a genetic base population for new breed development.