• Communications for Statistical Applications and Methods
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• v.13 no.2
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• pp.285-295
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• 2006

As more generic drugs become available, the quality, safety, and efficacy of generic drugs have become a public concern. Specifically, drug interchangeability among generic copies of the same brand-name drug is a safety concern. This research proposes a Bayesian method for assessing bioequivalence between two generic copies of the same brand-name drug from two independent $2{\times}2$ crossover design experiments. Uninformative priors are considered for general use and the posterior distribution of the difference of two generic drug effects is derived from which the highest probability density interval can be evaluated. Examples are presented for illustration.

• Ocean and Polar Research
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• v.34 no.1
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• pp.101-110
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• 2012

In this study, we attempted to provide Korean names to the arctic vascular plants observed around the Dasan Korean Arctic Station and Longyearbyen in Spitsbergen Island, in the Arctic region. To obtain recognizable results, plants were named according to the following naming rules. (1) When Korean names already existed, those names were used. (2) When there was no Korean name for a plant species, a scientific name for the plant was translated into a Korean name. (3) If the meaning of the scientific name was unclear, an English common name was translated into Korean name. (4) If the scientific names had meaning to the Arctic inhabitation, the Korean names included the word 'Buk-geuk'. (5) If the distribution of the plant was limited to the Arctic area or the original species lived in the polar region, the Korean name included the word 'Buk-geuk'. (6) If the plant had no Korean generic name, a particular suffix '~a-jae-bi' was added to the closely related genus name of the plant species, or a new Korean genus name was used by translating a common English name. (7) If the same generic name had two or more Korean names, a generic name that better reflected the characteristics of the plant was selected. In this paper, we reported Korean names for 46 plants species belonging to 15 families and 28 genera. Eight plants had an existing Korean name and the other species were given new Korean names based on the criteria outlined above. We also made new Korean generic names for three genera, Braya, Micranthes and Cassiope.

• Journal of the Korea Society of Computer and Information
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• v.26 no.2
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• pp.1-9
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• 2021

In this paper, we extend a generic library framework based on the state monad to exploit deterministic parallelism in a purely functional language Haskell and provide benchmarks for the extended features on a multicore machine. Although purely functional programs are known to be well-suited to exploit parallelism, unintended squential data dependencies could prohibit effective parallelism. Symbolic execution programs usually implement fresh name generation in order to prevent confusion between variables in different scope with the same name. Such implementations are often based on squential state management, working against parallelism. We provide reusable primitives to help developing parallel symbolic execution programs with unbound-genercis, a generic name-binding library for Haskell, avoiding sequential dependencies in fresh name generation. Our parallel extension does not modify the internal implementation of the unbound-generics library, having zero possibility of degrading existing serial implementations of symbolic execution based on unbound-genecrics. Therefore, our extension can be applied only to the parts of source code that need parallel speedup.

• Korean Journal of Weed Science
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• v.30 no.3
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• pp.308-321
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• 2010

To increase of weed researches, abbreviations for Korean weeds name(tentatively named 'KSWS code', the Korean Society Weed Science code) of 433 species belonging to 68 families in arable land were suggested in this paper. The KSWS code was derived from Bayer code or/and modified. The KSWS code was composed of alphabetic 5 characters, namely 3 characters in generic name and 2 characters in specific name. And variable species's KSWS code was 1 characters in generic name and 1 characters in variable name.

• Journal of the Korean Geographical Society
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• v.32 no.4
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• pp.479-490
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• 1997

This study attempted to grasp the etimological meaning of the ancient place name Dumo, and to identify when the ancient place names in Dumo system started to be used by Korean people. The results of analysis of generic toponym and specific toponym of the ancient place names in Dumo system are as follow: Firstly, Chumong, the name of the founder of the Koguryo Dynasty, and his two sons Biryu,the founder of the kingdom Biryu-Paekche, and Oncho, the founder of the kingdom Paekche, are presumed to originate from place name, not from person's name. Particularly, the name of Chumong is considered to be a person's name which comes from Dumo system. Oncho, who claimed to be a son of Chumong, a person of north-Puyo, transterred the capital of his kingdom to the present site of Dumo in Chunggung-dong, Hanam city in present, which is thought to be an early capital of Paekche or a part of it. Secondly, the word of Dumo means a warm space which is surrounded by mountains, protected from wind, endowed with river which provided with water. This kind of spatial cognition gradually evolved as the prototypical locational artifice which was diffused to Manchuria and Japan, and is believed to be introduced to the Korean Peninsula.

• ALGAE
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• v.22 no.2
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• pp.53-55
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• 2007

The name Palisada, which recently was proposed but not validly published for a new genus in the Laurencia complex,is validated by the provision of a Latin diagnosis. Relevant omenclatural changes for several species of Chondrophycus are included.

• Korean Journal of Clinical Pharmacy
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• v.27 no.2
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• pp.105-112
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• 2017

Background: Generic medications are approved on the basis of bioequivalence with brand medications in healthy volunteers rather than the target population, there remains a substantial uncertainty regarding their clinical effectiveness and safety. The object of this paper is to compare the clinical equivalence of generic statin drugs in patients. Methods: Literature published before September 2016, which is indexed in PubMed, EMBASE, RISS, comparing generic to brand products in statins. Outcomes included blood lipid level, proportion of days covered (adherence), hospitalization and mortality. Results: 511 citations were screened, of which 11 studies met eligibility criteria (6 randomized clinical trials, 5 observational studies). Generic atorvastatin was clinical equivalent with brand drugs in blood lipid level (3 RCTs) and generic simvastatin was also clinical equivalent with brand drugs (2 RCTs). 2 of 3 studies reported no significant difference in proportion of days covered except 1 study which reported generic statin significantly enhance proportion of days covered (p<0.001). Hospitalization was no significant difference in all studies (p>0.05). 1 study reported that all cause of mortality was significantly low in generic drugs (p<0.0001). Conclusion: Published data on comparing clinical efficacy of generic and brand statins were insufficient in both quantity and quality. This systematic review suggests that additional studies on clinical equivalence and safety of generic medications in patients would be needed.

• Journal of Pharmaceutical Investigation
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• v.32 no.4
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• pp.331-337
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• 2002

Nonproprietary name may be used without restriction by the public at large and can be called common name, generic name. Nomenclature agencies exist in US, Great Britain, Japan and so on. The agencies maintain liaison with onε another in an effort to secure the wide adoption of thε most appropriate and universally acceptable designation for each drug. To prevent the confusion which arises when several nonproprietary names are used for a single drug, either in the same country or in several different countries, the WHO has assumed the responsibility of coordination existing nomenclature at the international level. In this study, the nomenclature for new drugs and the terminology to harmonize specifications for revision of Korean Pharmacopoeia (KP) were established.

• Health Policy and Management
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• v.23 no.3
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• pp.210-223
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• 2013

Backgrounds: Escalating pharmaceutical expenditure has threatened the sustainability of National Health Insurance system in Korea. Generic medicines allow patients to access safe, effective, high-quality medicines at low cost, thus insurers could achieve significant financial savings by promotion of generics, if they are priced much lower than the originator. The purpose of this study was to review generic pricing as well as promotion policies in other countries and assess the implication of those policies. Methods: We reviewed the main measures adopted by the developed countries such as Austria, Belgium, Denmark, Finland, France, Germany, Italy, Japan, Netherlands, Norway, Sweden, United Kingdom, especially in countries where governments are the largest third-party payers or insurance finance resource is the national health insurance. Results: The foreign countries's experience with generic medicine policy shows that demand-side policies such as physician budgets, international nonproprietary name prescribing, generics substitution, patients co-payment as well as supply-side policies relating to pricing and reimbursement seems to play a critical role in developing the generic medicines market. Conclusion: Various strategy should be implemented to promote generic drug use.

• Journal of the Korean association of regional geographers
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• v.5 no.1
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• pp.1-24
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• 1999

This is a study on village names in a plain region of Changnyeong-Gun, a mountain region of Bonghwa-Gun and an island region of Namhae-Gun. The three regions differ in geographical features. The data are based on 455 village names in Changnyeong-Gun, 552 village names in Bonghwa-Gun and 275 village names in Namhae-Gun found in the 1 : 50,000 topographic map. The method of this study is to analyze the word structures of village names in the five basic concepts in geography : Man-Land(Natural Environment and Human Activities). Spatial Relation, Distribution, Region and Transition. The main results of this study are as follows: 1. Naming of villages are related to Natural Environment(41%), Human Activities(23%), Region(17%), Spatial Relation(13%), Distribution(5%), and Transition(3%). Of these six factors, Changnyeong-Gun is relatively dominant in village names related to Spatial Relations, Region and Transition ; Bonghwa-Gun Natural Environment and Namhae-Gun Human Activities and Spatial Relations. But the three Guns are absolutely dominant in village names related to Natural Environment and Human Activities. 2. A village name is divided into the specific name part(given name) and the generic name part(classified name). Names related to Human Activities, Spatial Relations, Distribution and Transition are more frequently found in the specific name part. Therefore, they are used as the given name of a village name. Whereas names related to Natural Environment and Region are more frequently found in generic name part, which means that they are used as the classified name of a village. 3. The word structure of a village name usually has two parts a frontal part(given name) and a rear part(classified name). The two parts have a particular pattern in the geographic concept when they are combined. 1) In the village names related to in their frontal part of the word structure, is more frequently combined as their rear part in Bonghwa-Gun, in Namhae-Gun and in Changnyeong-Gun. 2) In the village names related to in their frontal part of the word structure, is more frequently combined as their rear part in Changnyeong-Gun, in Namhae-Gun and in Bonghwa-Gun. Accordingly, Man(Human Activities) - Land (Natural Environment) can be considered the most important concept in the naming of villages, because the concept is most frequently used in the word structures of village names.