• Title/Summary/Keyword: General hospital

Search Result 9,047, Processing Time 0.031 seconds

Esophageal Rupture Due to Diving in Shallow Waters

  • Han, Sung Ho;Chon, Soon-Ho;Lee, Jong Hyun;Lee, Min Koo;Kwon, Oh Sang;Kim, Kyoung Hwan;Kim, Jung Suk;Lee, Ho hyoung;Chon, June Raphael
    • Journal of Trauma and Injury
    • /
    • v.31 no.1
    • /
    • pp.16-18
    • /
    • 2018
  • Delayed esophageal rupture due to blunt injury is not new. However, rupture due to suspected barotrauma is very rare. We describe a case of esophageal rupture in a male 24-year-old patient after diving in shallow waters. The patient was quadriplegic and could not experience the typical chest pain related to rupture and resulting mediastinitis. The rupture was discovered 4 days after emergency decompressive laminectomy and fusion for his cervical spine. The rupture was evidently caused by barotrauma and was discovered four days after admission. He underwent primary closure and pericardial flap as a life-saving procedure.

Differential Expression of DNA Repair Gene, N-Methylpurine-DNA Glycosylase Dduring the Development of Balb/c Mice (Balb/c 생쥐에서 DNA 회복효소인 N-Methylpurine-DNA Glycosylase(MPG)의 발생단계별 유전자 발현 조절)

  • Kim, Nam-Keun;Lee, Sook-Hwan;Kwak, In-Pyung;Han, Sei-Yul;Park, Chan;Lee, Hey-Kyung;Cha, Kwang-Eun;Cha, Kwang-Yul
    • Development and Reproduction
    • /
    • v.1 no.1
    • /
    • pp.37-43
    • /
    • 1997
  • DNA 회복효소인 MPG는 DNA의 퓨린기에 결합되어 있는 메틸기 등 이물질을 염기와 함께 제거하는 작용을 한다. 본 연구에서는 노던 블롯팅 방법을 이용하여 Balb/c mice의 각 조직별로 발생단계별 mRNA 발현 정도를 조사하였다. 뇌와 콩팥조직에서는 출생직후에 발현이 가장 활발하였으며, 성체시기까지 비교적 높은 활성도가 유지되었다. 위장 조직에서는 출생직후에서 일주일 후까지는 명확히 관찰되었으나, 그 이후는 발현이 약화되었다. 간장과 폐조직에서는 그 발현 정도가 매우 약했으며, 특히, 간조직의 경우 출생 직후보다 성체에서 그 발현이 현저히 감소되었다. 이들 조직에서의 활성도는 출생후 24시간 이내에서 1주일후까지 상대적으로 높게 유지되다가 점차 감소되었다. 즉, 수유기(출생직후부터 1주일후)에는 그 활성도가 성체시기(4주에서 6개월)보다 높게 유지되었다. 이러한 결과들로 미루어 보아 늙은 생쥐가 젊고 어린 생쥐보다 alkylating mutagen들에 노출되었을대 암에 걸릴 위험성이 높다고 생각된다.

  • PDF

Meta-analysis of the Efficacy of Sorafenib for Hepatocellular Carcinoma

  • Wang, Zhao;Wu, Xiao-Ling;Zeng, Wei-Zheng;Xu, Gui-Sen;Xu, Hui;Weng, Min;Hou, Juan-Ni;Jiang, Ming-De
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.2
    • /
    • pp.691-694
    • /
    • 2013
  • Purpose: By carrying out a meta-analysis of randomized controlled trials that compared sorafenib or combined chemotherapy with placebo or combined chemotherapy, the effectiveness of sorafenib in hepatocellular carcinoma was evaluated in the present study, which also provided clinical practice guidelines of evidence-based-medicine. Methods: We reviewed PubMed citations concerning sorafenib treating hepatocellular carcinoma in randomized controlled trials from Jan 2000 to July 2012. All the literature was extracted by Cochrane systematic reviews and underwent meta-analysis with RewMan 5.0 software. Results: Finally, four papers documenting randomized controlled studies were included. Compared with controls, sorafenib was shown to significantly increase overall survival (OS), time to progression (TTP), and disease control rates (DCR), but not the time to symptom progression (TTSP) in hepatocellular carcinoma patients. The incidence of grade-III/IV adverse reactions, including hand-foot-skin reactions, diarrhea, hypertension and skin rash or desquamation, in sorafenib treatment group was higher than that in controls. However, there was no significant difference in the incidence of hypodynamia between the two groups. Conclusions: Sorafenib exerts significant curative effects in hepatocellular carcinoma.

A Case of Primary Pulmonary Leiomyosarcoma (우폐하엽의 원발성 평활근육종 1예)

  • Hong, Han-Ki;Baik, Jung-Min;Oh, Young-Bae;Kim, Hee-Yeon;Lee, Chan-Joo;Lee, Sang-Moo;Bak, Man-Sil;Kim, Eun-Kyoung
    • Tuberculosis and Respiratory Diseases
    • /
    • v.44 no.2
    • /
    • pp.419-424
    • /
    • 1997
  • Primary Pulmonary leiomyosarcomas are rare tumors. These tumors may arise at any level of the lung in which smooth muscle fibers are found. The highest incidence of sarcoma is during the fourth decade whereas for bronchogenic carcinoma the maximum incidence is during the sixth and seventh decades. Leiomyosarcomas are aggressive and progressive. Treatment is mainly surgical. The chemotherapy is ineffective and the effectiveness of radiotherapy depends on the total dose of irradiation. Prognosis and significant survival rate are related to the size of the lesion. We report one patient with primary pulmonary leiomyosarcoma involving the right lower lung.

  • PDF

Myoclonus as the Presenting Symptom of Hashimoto's Encephalopathy (근육간대경련으로 발현된 하시모토 뇌병증)

  • Chung, Curie;Nam, Jungmoo;Hwang, Suntae;Kim, Byung-Kun;Koo, Ja-Seong;Kwon, Ohyun;Park, Jong-Moo;Lee, Jung Ju
    • Annals of Clinical Neurophysiology
    • /
    • v.9 no.2
    • /
    • pp.85-88
    • /
    • 2007
  • Hashimoto's encephalopathy has been described as a steroid-responsive syndrome of encephalopathy associated with high serum concentration of anti-thyroid antibodies. We report a 67-year-old woman who presented with myoclonus involving both upper extremities. Brain MRI and EEG showed no diagnostic abnormalities. Thyroid functions were normal, but anti-thyroid antibodies were elevated both in serum and in CSF. Hashimoto's encephalopathy can present with myoclonus even without outstanding encephalopathic feature, therefore anti-thyroid antibody test should be included in diagnostic test in patient with myoclonus.

  • PDF

Prognostic Value of Preoperative Inflammation-Based Prognostic Scores on Hospital Mortality after Gastric Cancer Surgery

  • Dinc, Tolga;Yildiz, Baris Dogu;Kayilioglu, Ilgaz;Sozen, Isa;Tez, Mesut;Coskun, Faruk
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.18
    • /
    • pp.7909-7911
    • /
    • 2014
  • Gastric cancer is the fourth most common malignancy worldwide. Poor prognosis in gastric cancer is linked with hypoalbuminemia. Previous studies demonstrated relationships between gastric cancer and chronic inflammation. The aim of this study was to assess the prognostic value of preoperative inflammation-based prognostic scores regarding hospital mortality after gastrectomy. Unlike other recent articles on the same topic; we could only verify prognostic value of prognostic nutritional index for in hospital mortality after surgery.

Giant Benign Schwannoma Involving Sacral Bone - A Case Report - (천골부에 발생한 거대 신경초종 - 증 례 보 고 -)

  • Oh, Kyung Seup;Ha, Sung Il;Lee, Hyun Sung;Lee, Jong Soo;Kwak, Seung Su;Yun, Suk Hoon
    • Journal of Korean Neurosurgical Society
    • /
    • v.30 no.4
    • /
    • pp.509-513
    • /
    • 2001
  • Sacral schwannoma is a rare lesion with a tendency to reach large proportions. The benign schwannoma rarely involves the vertebral bodies extensively. The authors report a case of giant intrasacral schwannoma in 30-year-old woman who had intermittent lower back pain during 3 years period. CT and MRI showed a destructive mass lesion within the upper part of sacrum with a large mass extending into the presacral space. The patient underwent combined surgery consisted of anterior transabdominal approach and posterior sacral laminectomy and total removal of tumor. The characteristics of the lesion were discussed with a review of literatures.

  • PDF

Factors Influencing on Hospital Choice of the General Hospital among Mongolian Customers with Loyalty (몽골 종합병원 충성고객의 병원선택에 영향을 미치는 요인)

  • Lee, Hyun Sook
    • Korea Journal of Hospital Management
    • /
    • v.26 no.2
    • /
    • pp.68-78
    • /
    • 2021
  • Background:The purpose of this study was to identify factors influencing on hospital choice of the general hospital among customers with loyalty in Mongolia. Methods:This study was divided into 5 types of hospital choice factor such as physical, human, efficiency, accessibility, and hospital image. Data were assessed using 229 patients who visit at a general hospital in Mongolia. The collected data from June 20 to July 20 in 2020 were conducted the self-administered questionnaires and analyzed frequency, t-test, ANOVA, and logistic regression by using SPSS 25.0. Results:The level of education was significant in the mean difference of customer types by demographic characteristics. Expecially, factors affecting hospital choice of loyalty customers were human and hospital image. Conclusion:This study suggests that it is necessary to understand present and potential consumer's needs, wants, and demands. Also, it is important to concern about aspect of marketing strategy of the general hospital in Mongolia.

Nurse Staffing Level Relating Factors of the General Nursing Units, ICU, ER and OR in Acute General Hospitals (종합병원의 일반병동, 중환자실, 응급실, 수술장간호사 확보수준 관련 요인)

  • Kim, Yun-Mi
    • Journal of Korean Academy of Nursing Administration
    • /
    • v.14 no.4
    • /
    • pp.404-412
    • /
    • 2008
  • Purpose: To analyse hospital nurse staffing level of the general nursing unit, ICU, ER and OR in general hospitals. Method: The study sample was 105 acute general hospitals which had reported the bed size and number of nurses by the nursing units. Number of bed per nurse was analysed by the hospital characteristics and the staffing levels of the doctors and the nursing assistant personnels using t-test or ANOVA and Pearson's correlation. Results: Number of bed per nurse was 3.86 in general nursing units and 0.95 in ICU. Tertiary hospitals employed more nurses in general nursing units and ICU than general hospitals. Hospitals located in Seoul and public hospitals employed more ICU nurses. OR nurse staffing level was higher in academic hospitals. Hospital size was positively correlated with nurse staffing level of the general nursing unit, ICU, ER and OR respectively. Total nurse staffing level of the hospital was positively correlated with doctor and nursing assistant personnels staffing levels. Conclusion : Differentiated nursing fee schedule was needed to implement in ER or OR. Regulation policy should be needed for the hospitals which violated hospital nurse staffing level of the law.

  • PDF