• Title/Summary/Keyword: Gene inheritance

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The Limit of Gene-Culture Co-evolutionary Theory

  • Lee, Min-seop;Jang, Dayk
    • Korean Journal of Cognitive Science
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    • v.28 no.3
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    • pp.173-191
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    • 2017
  • The theories of cultural evolution hold subtly or clearly different stances about definition of culture, pattern of cultural evolution, biases that affect cultural evolution, and relationship between culture and organism. However, the cultural evolution theories have a common problem to solve: As the evolutionary theory of life tries to explain the early steps and the origin of life, the cultural evolution theories also must explain the early steps of the cultural evolution and the role of the human capability that makes cultural evolution possible. Therefore, explanations of the human's unique traits including the cultural ability are related to determine which one is the most plausible among many cultural evolution theories. Theories that tried to explain human uniqueness commonly depict the coevolution of gene (organism) and culture. We will explicitly call the niche construction theory and the dual inheritance theory the 'gene-culture co-evolutionary theory'. In these theories, the most important concept is the 'concept of positive feedback'. In this paper, we distinguish between core positive feedback and marginal positive feedback, according to whether the trait that the concept of positive feedback explains is the trait of human uniqueness. Both types of positive feedback effectively explain the generality of human uniqueness and the diversity of human traits driven by cultural groups. However, this positive feedback requires an end, in contrast to negative feedback which can be continued in order to maintain homeostasis. We argue that the co-evolutionary process in the gene-culture co-evolutionary theories include only the positive feedback, not covering the cultural evolution after the positive feedback. This thesis strives to define the coevolution concept more comprehensively by suggesting the potential relationships between gene and culture after the positive feedback.

Complex Segregation Analysis of Total Milk Yield in Churra Dairy Ewes

  • Ilahi, Houcine;Othmane, M. Houcine
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.3
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    • pp.330-335
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    • 2011
  • The mode of inheritance of total milk yield and its genetic parameters were investigated in Churra dairy sheep through segregation analyses using a Monte Carlo Markov Chains (MCMC) method. Data which consisted of 7,126 lactations belonging to 5,154 ewes were collected between 1999 and 2002 from 15 Spanish Churra dairy flocks. A postulated major gene was assumed to be additive and priors used for variance components were uniform. Based on 50 000 Gibbs samples from ten replicates chains of 100,000 cycles, the estimated marginal posterior means${\pm}$posterior standard deviations of variance components of milk yield were $23.17{\pm}18.42$, $65.20{\pm}25.05$, $120.40{\pm}42.12$ and $420.83{\pm}40.26$ for major gene variance ($\sigma_G^2$), polygenic variance ($\sigma_u^2$), permanent environmental variance ($\sigma_{pe}^2$) and error variance ($\sigma_e^2$), respectively. The results of this study showed the postulated major locus was not significant, and the 95% highest posterior density regions ($HPDs_{95%}$) of most major gene parameters included 0, and particularly for the major gene variance. The estimated transmission probabilities for the 95% highest posterior density regions ($HPDs_{95%}$) were overlapped. These results indicated that segregation of a major gene was unlikely and that the mode of inheritance of total milk yield in Churra dairy sheep is purely polygenic. Based on 50,000 Gibbs samples from ten replicates chains of 100,000 cycles, the estimated polygenic heritability and repeatability were $h^2=0.20{\pm}0.05$ and r=$0.34{\pm}0.06$, respectively.

Identification and Characterization of Novel Sequences of ev21-K Locus for Feather-Sexing in Chickens

  • Eun Jung Cho;Sea Hwan Sohn
    • Korean Journal of Poultry Science
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    • v.51 no.2
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    • pp.117-125
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    • 2024
  • This study aimed to find genetic markers for breed-independent identification of early- and late-feathering chickens. We explored the novel sequences of the ev21-K locus associated with late-feathering and investigated its characterization. Additionally, the genetic transmission pattern of the identified sequences were investigated to understand its potential application in auto-sexing lines. A total of 707 chickens from 5 chicken breeds were employed for the study. The ev21-K locus was identified through a comparative analysis of the ev21 gene and the K gene related to feather development. For analysis of identified loci, specific primers for the target sequences were prepared and polymerase chain reaction (PCR) was performed to obtain the products, and then their nucleotide sequences were analyzed. Crossbreeding tests of early-feathering and late-feathering chickens were conducted to examine the genetic transmission patterns of the identified sequences. The results showed that the identified 230 bp ev21-K locus, which named as ev21-related K specific sequences were 99% homology with the ev21 gene. PCR analysis confirmed its presence exclusively in late-feathering chickens. Comparative analyses across tissues, breeds, and ages demonstrated the sequences consistency in identifying late-feathering chickens. Genetic transmission patterns were investigated through crossbreeding tests, revealing sex-linked inheritance and consistent segregation with feathering phenotypes. The inheritance patterns of the ev21-related K specific sequences demonstrated that this locus follows the typical Mendelian inheritance pattern as a dominant gene. In conclusion, the novel sequences of ev21-K locus were a reliable molecular marker for identifying early- and late-feathering chickens across breeds.

Enhanced stability of Pseudomonas sp. Endo-1,4-$\beta$$\beta$-1,4-Glucosidase Gene (Pseudomonas sp. 유래 Endo-1,4-$\beta$-Glucanase 및$\beta$-1,4-Glucosidase 유전자의 안정성 개선)

  • Kim, Yang-Woo;Chun, Sung-Sik;Chung, Young-Chul;Roh, Jong-Soo;Sung, Nack-Kie
    • Microbiology and Biotechnology Letters
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    • v.23 no.6
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    • pp.659-664
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    • 1995
  • To improve stability of recombinant DNA pLC1 encoding endoglucanase gene and pGL1 encoding $\beta $-glucosidase gene, DNA fragments of genes coding endoglucanase and $\beta $-glucosidase were cloned within the recA gene on a pDR1453, and the pDRE10 and pDRG20 of recombinant plasmids were integrated into the recA gene on the E. coli 1100 chromosomal DNAs. The stability of inheritance was completely maintained in E. coli 1100; Transformants E. coli 1100/pDREIO and pDRG20 were expressed well by recA promoter and increased endoglucanase and $\beta $-glucosidase activities. This method can be used as a model to improve the stability of recombinant plasmid in large scale culture.

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Inheritance of Fenvalerate Resistance in the Diamondback Moth, Plutella xylostella Linne(Lepidoptera: Yponomeutidae) (배추좀나방의 Fenvalerate에 대한 저항성 유전)

  • 김길하;이준호;조광연
    • Korean journal of applied entomology
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    • v.30 no.2
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    • pp.106-110
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    • 1991
  • The mode of inheritance of resistance to fenvalerate in the diamondback moth (Plutella xylostella L.) was studied using insecticide susceptibility and mixed function oxidase tests. Tehre were no differences in the concentration-mortality relationships between $F_1$ progenies $(S_{female}\timesR_{male},\;R_{female}\timesS_{male})$ obtained from reciprocal crosses with the susceptible and fenvalerate-selected strains(R), indicating the absence of sex-linked inheritance. Degree of dominance of the $F_1$ progenies $(S_{female}\timesR_{male},\;R_{female}\timesS_{male})$ were -0.50 and -0.46, respectively, in the insecticide susceptibility test and -0.85 and -0.81, respectively, in the mixed function oxidase test. These results suggest that inheritance of fenvalerate resistance is controlled by and incompletely recessive autosomal gene.

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A Conception Analysis on Reproduction and Inheritance of Elementary Preservice Teachers (예비초등교사들의 생식 및 유전에 관한 개념 분석)

  • Hong Seung-Ho
    • Journal of Korean Elementary Science Education
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    • v.24 no.4
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    • pp.351-359
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    • 2005
  • The aims of this research are to analyze elementary preservice teacher's conception and causes of their misconceptions on biological reproduction and inheritance. In future, it would be also to provide useful data for the effective teaching-teaming method in the elementary school as well as opportunities to correct their misconceptions, which help elementary preservice teachers have the appropriate scientific conceptions. Thirty kinds of test questions were designed in science curriculum for elementary students and biology textbook for university students in order to develop reproduction and inheritance's concepts. The questionnaire was given to 166 junior students of university of education in a local city. All statistical analysis was performed using SPSS version 10.0 program. The major results are as follows: Among 30 test questions, 2 questions in plants, 5 questions in animals and 2 questions in gene were appeared as misconceptions over $50\%$. The major reason to hold the misconceptions was influenced by 'learning up to now' category. The selection reasons of response were significantly different between scientific conceptions and misconceptions in 10 questions by analysis of variance. The gender also showed statistically significant differences between scientific conception and misconception in 3 questions by $\chi^2$ test. The selection reasons according to gender were significantly different between male and female students in 5 questions. For the reasons in forming misconceptions, they may cause by stereotype, conscious priority, differences of experiences, interest or attention, lack of professional Knowledge, and so on. Therefore, it was concluded that this research may help elementary preservice teachers to reconsider their conception for reproduction and inheritance and to be successful in science instructions fur elementary students.

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Genetic Variation in Exon 3 of Human Apo B mRNA Editing Protein (apobec-1) Gene

  • Hong, Seung-Ho;Song, Jung-Han;Kim, Jin-Q
    • Journal of Genetic Medicine
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    • v.3 no.1
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    • pp.15-19
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    • 1999
  • We have investigated the genetic variation in the human apo B mRNA editing protein (apobec-1) gene. Exon 3 of the apobec-1 gene was amplified by polymerase chain reaction. After detection of an additional band by single strand conformational polymorphism (SSCP) analysis, sequencing of the SSCP-shift sample revealed a single-base mutation. The mutation was a CGG transversion at codon 80 resulting in a lleRMet substitution. This substitution was confirmed by restriction fragment length polymorphism analysis since a Pvull site is abolished by the substitution. Population and family studies confirmed that the inheritance of the genotypes for apobec-1 gene polymorphism is controlled by two codominant alleles (P1 and P2). A significant difference in plasma triglyceride was detected among the different apobec-1 genotypes in the CAD patients (P<0.05). Our study could provide the basis for elucidating the interaction between genetic variation of the apobec-1 gene and disorders related to lipid metabolism.

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Detection of Mendelian and Parent-of-origin Quantitative Trait Loci for Meat Quality in a Cross between Korean Native Pig and Landrace

  • Choi, B.H.;Lee, Y.M.;Alam, M.;Lee, J.H.;Kim, T.H.;Kim, K.S.;Kim, J.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.12
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    • pp.1644-1650
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    • 2011
  • This study was conducted to detect quantitative trait loci (QTL) affecting meat quality in an $F_2$ reference population of Korean native pig and Landrace crossbreds. The three-generation mapping population was generated with 411 progeny from 38 $F_2$ full-sib families, and 133 genetic markers were used to produce a sex-average map of the 17 autosomes. The data set was analyzed using least squares Mendelian and parent-of-origin interval-mapping models. Lack-of-fit tests between models were used to characterize the QTL for mode of gene expressions. A total of 10 (32) QTL were detected at the 5% genome (chromosome)-wise level for the analyzed traits. Of the 42 QTL detected, 13 QTL were classified as Mendelian, 10 as paternal, 14 as maternal, and 5 as partial expressed QTL, respectively. Among the QTL detected at 5% genome-wise level, four QTL had Mendelian mode of inheritance on SSCs 5, 10, 12, and 13 for cooking loss, drip loss, crude lipid and crude protein, respectively; two QTL maternal inheritance for pH at 24-h and shear force on SSC11; three QTL paternal inheritance for CIE b and Hunter b on SSC9 and for cooking loss on SSC15; and one QTL partial expression for crude ash on SSC13, respectively. Most of the Mendelian QTL (9 of 13) had a dominant mode of gene action, suggesting potential utilization of heterosis for genetic improvement of meat quality within the cross population via marker-assisted selection.

Resistance to Bombyx mori Densonucleosis Virus Type 1 and Its Inheritance in Silkworm, Bombyx mori L.

  • Sen, Ratna;Nataraju, B.;Balavenkatasubbaiah, M.;Premalatha, V.;Thiagarajan, V.;Datta, R.K.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.9 no.1
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    • pp.35-40
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    • 2004
  • Bombyx mori densonucleosis virus type 1 (BmDNV1)- a non occluded virus causes flacherie disease in the susceptible stocks of the silkworm, Bombyx mori. However, some stocks are non-susceptible. Non-susceptibility to BmDNV1 in B. mori is a unique case where the virus infection is completely inhibited by a single gene of the host. A survey conducted by this institute in some parts of Karnataka state has revealed that, 43.05% of the total incidence of flacherie disease caused by non-occluded viruses, are due to the synergistic infection of B. mori densonucleosis and infectious flacherie virus. Earlier study indicated that rearing of BmDNV1 resistant silkworm stock is effective in protecting silkworm against BmIFV also. In the present study the response of 78 silkworm stocks which include 42 of non-diapausing and 36 of diapausing groups, to BmDNV1 is investigated. Newly ecdysed third instar larvae were inoculated per-os with 10% inoculum of BmDNV1 extracted from the mid-gut of infected silkworm. One non-diapausing and three diapausing silkworm stocks were found to be resistant to BmDNV1. Eleven silkworm stocks were found to possess moderate resistance whereas rest sixty three were found to be susceptible to BmDNV1. Genetic analysis has shown that the resistance to BmDNV1 is autosomally inherited and controlled by a major dominant or a major recessive gene in different silkworm stocks. These resistant stocks can be utilized as the resource material to develop BmDNV1 resistant commercial hybrids. The selection strategies, depending upon the mode of inheritance of resistance in the resource material chosen, are discussed.

Effects of using Umbilical Hernia Animals as Breeding Pigs on the Reproductive Traits (배꼽탈장(umbilical hernia)돼지의 종돈 활용이 번식형질에 미치는 영향)

  • Han, Sang-Hyun;Cho, In-Cheol;Cho, Yong-Il;Park, Yong-Sang;Kang, Tae-Young
    • Journal of Veterinary Clinics
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    • v.34 no.2
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    • pp.126-131
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    • 2017
  • This study investigated the incidence rate of umbilical hernia (UH) in pig farms and examined the effect of using them as breeding pigs on reproductive traits. The occurrence of UH ranged from 0.1% to 3.0% in pig farms investigated. UH pigs were found in almost all farms except for a single farm in Jeju Island. Spontaneously occurring UH pigs were selected and used for cross breeding tests. UH-related crosses and their progeny showed significant (P < 0.05) differences in gestation period, the numbers of piglets born and alive, and body weights at birth and $21^{st}$ day comparing to those of the control population. UH-related crosses showed longer gestation period, reduced numbers of piglets, and lighter body weights than those from the control population. Interestingly, reduced number of piglets was about one fourth, suggesting that UH inheritance might play a critical role as a lethal gene during embryogenesis. In addition, UH incidence rate in UH-related crosses was significantly (P < 0.05) higher than that in the control except for UH-cross3. However, in the progeny of control cross, a pig also had UH appearance, indicating that porcine UH might be inherited in recessive inheritance mode. Taken together, the results of this study indicate that UH is one of recessively inherited genetic defect that occurs at ordinary times in pig farms, suggesting that the use of UH animals as sire and/or dam may lead to economic losses due to increased gestation period, reduced numbers of piglets born and alive, and lower growth rates after birth of pigs.