• Journal of Nutrition and Health
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• 제50권3호
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• pp.217-224
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• 2017

Purpose: Although it is well known thatmortality and morbidity due to cardiovascular diseases are higher in salt-sensitive subjects than in salt-resistant subjects, their underlying mechanisms related to obesity remain unclear. Here, we focused on salt-sensitive gene variants unrelated to monogenic obesity that interacted with sodium intake in humans. Methods: This review was written based on the modified $3^rd$ step of Khans' systematic review. Instead of the literature, subject genes were based on candidate genes screened from our preliminary Genome-Wide Association Study (GWAS). Finally, literature related to five genes strongly associated with salt sensitivity were analyzed to elucidate the mechanism of obesity. Results: Salt sensitivity is a measure of how blood pressure responds to salt intake, and people are either salt-sensitive or salt-resistant. Otherwise, dietary sodium restriction may not be beneficial for everyone since salt sensitivity may be associated with inherited susceptibility. According to our previous GWAS studies, 10 candidate genes and 11 single nucleotide polymorphisms (SNPs) associated with salt sensitivity were suggested, including angiotensin converting enzyme (ACE), ${\alpha}$-adducin1 (ADD1), angiotensinogen (AGT), cytochrome P450 family 11-subfamily ${\beta}$-2 ($CYP11{\beta}$-2), epithelial sodium channel (ENaC), G-protein b3 subunit (GNB3), G protein-coupled receptor kinases type 4 (GRK4 A142V, GRK4 A486V), $11{\beta}$-hydroxysteroid dehydrogenase type-2 (HSD $11{\beta}$-2), neural precursor cell-expressed developmentally down regulated 4 like (NEDD4L),and solute carrier family 12(sodium/chloride transporters)-member 3 (SLC 12A3). We found that polymorphisms of salt-sensitive genes such as ACE, $CYP11{\beta}$-2, GRK4, SLC12A3, and GNB3 may be positively associated with human obesity. Conclusion: Despite gender, ethnic, and age differences in genetics studies, hypertensive obese children and adults who are carriers of specific salt-sensitive genes are recommended to reduce their sodium intake. We believe that our findings can contribute to the prevention of early-onset of chronic diseases in obese children by facilitating personalized diet-management of obesity from childhood to adulthood.

• 임상간호연구
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• 제21권2호
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• pp.188-195
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• 2015

Purpose: The purpose of this study was to evaluate the appropriateness of the replacement time intervals of 18 gauge peripheral intravenous catheters (PICs) by investigating the development of phlebitis. Methods: The subjects were 200 hospitalized patients over 18 yrs old aged who have 18 gauge PICs placed for surgery. After the insertion of PICs, the researcher monitored the insertion site daily for 96 hours for any signs of phlebitis. Results: Phlebitis developed in 25.7% of patients. Patients who developed phlebitis were significantly older and were receiving fluids with faster infusion rate. However, patients with and without phlebitis were not different by gender, insertion site, fluid osmolality, or pH of drugs administered. The incidence rate of phlebitis was higher than 10%(12.9%) starting 24~48 hours after the insertion of 18 gauge PICs. Conclusion: It is recommended to replace 18 gauge PICs within 24~48 hours after insertion. Close monitoring of the PICs insertion site for the signs of phlebitis is recommended.

• 수산해양교육연구
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• 제24권3호
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• pp.355-367
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• 2012

This paper focuses on understanding what kind of experience the women leadership education can provide for adult learners and how the learners grasp a characteristic of a women leader. For this, the research interviewed learner who complete the women leadership course at the P center in Busan. To this end, it is discussed in two sides. One side is about educational experience, the other side is about leadership. In the aspect of former approach, the leadership education shows the characteristic which is much closer to the meaning of the education itself rather than that of leadership. It not only put much emphasize on the recovery to the self but also shows the relation-oriented characteristic like building up social net-work. In the aspect of the latter, by connecting the woman and leader, women expects they wish to be a 'trustful leader'. For them, 'trustful leader' is the true leader. In addition it also means 'charismatic leader', 'servant leader', 'the leader with member to growth' and 'the leader with a rational and reasonable'. Although women acknowledge that women leader's authority and power is important for the realization of the real equality of women, at the same time, however, they worry about the possibility that this leader become a kind of a 'power-oriented leader' which causes conflict and suppress the weaker. This study argues that we need to concentrate more on the new perspective which focuses on the sharing and bordering occurred in inner gender rather than the former approach which focuses on the difference between genders.

• 미생물학회지
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• 제55권1호
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• pp.25-32
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• 2019

Influenza A (H1N1) virus caused a worldwide pandemic in 2009-2010 and still remains in seasonal circulation. Continuous surveillance activities are encouraged in the post pandemic phase to watch over the trend of occurrence every year, this is better to be done by a rapid and sensitive method for its detection. This study was conducted to detect proportions of occurrence of influenza A virus (H1N1) in patients with influenza-like illness. Samples from 500 patients with influenza or influenza-like clinical presentation were tested by real-time reverse transcription polymerase chain reaction (RT-PCR) and virus tissue culture. Among the total 500 participants, 193 (38.6%) were females and 307 (61.4%) males. Seventy-one patients (14.2%) were positive for H1N1 virus infection with real-time RT-PCR while 52 (10.4%) were positive by tissue culture. Non-statistically significant relation was found between age and gender with the positivity of H1N1. Sensitivity and specificity of real-time RT-PCR was 98.08% and 95.54%, respectively, in comparison to virus isolation with accuracy 95.8%. This study showed that H1N1 virus was responsible for a good proportion of influenza during the post-pandemic period. Real-time RT-PCR provides rapidity and sensitivity for the detection of influenza A virus (H1N1) compared with virus isolation and thus it is recommended as a diagnostic tool.

• Journal of Ecology and Environment
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• 제42권4호
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• pp.139-149
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• 2018

Background: Ethiopia is among the poorest countries where land degradation caused livelihood problem to its inhabitants. The livelihood of rural communities in Ethiopia is seriously threatened by land degradation. Land is the major natural resource that economic, social, infrastructure, and other human activities are undertaken on. Thus, land resources play an important role in shaping rural livelihoods, and lack of sustainable land management practices leads to land degradation. Thus, this study aimed to analyze interlink between land degradation and livelihood of rural communities in Chilga district, Northwest Ethiopia. It also addresses the factors which influence income diversification for livelihood of households in the study area. Result: The result depicts that the major causes of land degradation are both natural and anthropogenic. Land degradation and livelihood are negatively interlinked with each other. The livelihood of the majority of the population in the study area is dependent on subsistence agriculture both farming and animal husbandry with low diversification. The survey result showed that more than half (69%) of the sample households have farm size of less than 2 ha, nearly one third (31%) have 2.0-2.5 ha, and insignificant number of farmers have more than 2.5 ha. More than 80% of the respondents pointed out that land degradation has impacts both on crop yield and livestock production. Most of the explanatory variables such as gender, age, education level, farmland size, and family size have statistical significant influence (at P < .01 and P < .05 levels) for income diversification of households, while marital status on the other hand is not statistically significant though it has positive relation with income diversification in this study. Conclusions: Our results suggest awareness should be created in the community about the livelihood diversification mechanisms which enabled them to engage in different income-generating activities and comprehensive watershed management should be implemented.

• 융합정보논문지
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• 제9권2호
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• pp.121-129
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• 2019

본 연구는 부모 간 갈등이 공격성을 매개로 하여 남녀 청소년의 또래관계에 미치는 영향을 살펴보는 것을 목적으로 하였다. 본 연구의 대상은 서울시에 있는 중학교 3학년에 재학 중인 남녀 학생 482명이었다. 본 연구의 자료를 분석한 결과를 요약하면 다음과 같다. 첫째, 남자 청소년과 여자 청소년이 인식하는 부모 간 갈등에서는 유의한 차이가 나타나지 않았으나, 공격성과 또래관계에서는 성별에 따른 유의한 차이가 나타났다. 둘째, 부모 간 갈등과 공격성, 또래관계 간에 유의한 상관관계가 있는 것으로 밝혀졌다. 셋째, 부모 간 갈등이 청소년의 또래관계에 미치는 영향에 대한 공격성의 매개효과를 분석한 결과, 남자 청소년 집단에서는 부모 간 갈등이 공격성에 부분매개 되어 남자 청소년의 또래관계에 영향을 미치는 것으로 나타났다. 여자 청소년 집단에서는 부모 간 갈등이 또래관계에 미치는 영향에서 공격성이 완전매개 역할을 하는 것으로 나타났다. 본 연구의 결과는 청소년의 또래관계를 청소년의 부모 및 가족 경험과 청소년 개인의 심리 정서 맥락에서 이해할 필요가 있다는 것을 제시한다.

• 한국콘텐츠학회논문지
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• 제19권3호
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• pp.385-395
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• 2019

본 연구에서는 죄책감, 수치심, 수줍음, 내부 적대감을 포함하는 자의식적 부정정서와 비자살적 자해의 관계에서 정서조절기제의 매개효과를 규명하고자 하였다. 본 연구의 대상은 J지역 3개 대학교에 재학 중인 대학생 652명으로, 이들에게 비자살적 자해, 자의식적 부정정서, 정서조절에 대한 자기보고식 설문지를 실시하였다. Process macro의 model 4를 사용한 매개분석 결과, 자의식적 부정정서는 자해행동과 유의한 관련성을 보였으며, 부정적 반추의 정서조절이 그 관련성을 매개하는 것으로 나타났다. 이러한 결과는 자의식적 부정정서가 높을수록 비자살적 자해 행동이 증가하며, 부정적 반추가 부정정서를 더욱 강화시켜 자해 행동을 증폭시킴을 확인할 수 있었다.

• 치위생과학회지
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• 제19권1호
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• pp.23-30
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• 2019

Background: The health of the economically active population contributes to increased corporate productivity by reducing the productivity loss caused by disease and increasing job efficiency, which in turn is a national benefit. Since the economically active population is a concept encompassing workers and a source of economic development for a country, that population's health should be treated with importance not only from a personal standpoint but also at a national level. Methods: In this study, data of 11,007 adults aged 20 years and older who participate in economic activities were analyzed in the five-year Korea Health Panel Study from 2010 to 2014 including the number of dental visits and dental medical expenses. Results: Factors related to "gender," "education level," "age," "duty category," "income level," "employment type," "national health insurance," and "chronic disease status" of the economically active population are affected in relation to the number of visits and dental medical expenses. The number of dental visits increased with higher education levels (p<0.001), and the number of visits to the dentist increased with older age (p <0.001). Dental medical expenses were 91,806 Korean won (KRW) more for "white-collar workers" than for "blue-collar workers" (p<0.03), and 127,674 KRW more for "regular workers" than for "atypical workers" (p<0.02). Conclusion: When it is necessary to improve policies to enhance the efficiency of the distribution of health and medical resources in the overall balance of the dental health sector, we should try to identify various factors of oral health disorder due to income inequality among the classes according to the country's employment type in order to find ways to reduce the health gap among the social classes.

• 한국방사선학회논문지
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• 제13권4호
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• pp.531-537
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• 2019

본 연구는 복부 초음파 검사를 통해 확인된 지방간 환자의 지방간 정도에 따른 혈액학적 고지혈증 지표와의 관련성을 분석하여 관련 연구에 기초자료를 제공하고자 시행되었다. 2017년 1월 1일부터 2017년 12월 31일까지 총 412명의 성인을 대상으로 하였으며, 복부초음파 검사를 진행하여 지방간이 확인된 환자 중 초음파 검사 시행일 기준 3개월 이내의 혈액학적 데이터가 있는 환자를 대상으로 후향적 분석을 실시하였다. 연구결과, 지방간 정도에 따른 혈액학적 수치는 중성지방, AST, ALT에서 통계적으로 유의한 차이가 있었고(p<.05), 지방간은 전체 변수 중 성별, 중성지방, AST, ALT와 관련성이 있었다(p<.05). 결론적으로 지방간 정도는 고지혈증의 혈액학적 수치와 직접적인 영향인자는 아니었지만 그 관련성 확인을 통해 지방간과 고지혈증 동반 관리의 필요성을 확인했다.

• 대한치과기공학회지
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• 제41권2호
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• pp.103-112
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• 2019

Purpose: This article tried to find the relations between periodontal diseases, body mass index and clinical level for Korean adults over the age of 19, utilizing data of the 6th national nutrition survey. Methods: In the collected data, 14,940 adults aged 19 years or older were included in the study to determine the relationship between the general health status of Korean adults and periodontal disease. Results: As the result, 28.6% of Korean adults had periodontal diseases, there were significant differences depending on gender, age, smoking, residential aria, education level, body mass index, HDL-cholesterol, leukocyte value and fasting blood sugar. When general factors were controlled for multiple logistic regression analysis, there was significance as BMI cross rate was 1.029(95% C1, 1.007-1.051). HDL-cholesterol cross rate was 0.989(95% C1, 0.980-0.999), leukocyte cross rate was 1.086(95% C1, 1.040-1.134) and fasting bloody sugar cross rate was 1.006(95% C1, 1.003-1.009), so there were significance. In conclusion, there was a significance relation between periodontal diseases, body mass index, HDL-cholesterol and fasting bloody sugar. Conclusion: Based on the results of this study, oral health education should be used to manage and maintain healthy oral cavity by improving periodontal disease management and awareness. In addition, it will be necessary to develop periodic oral examinations and age - specific oral health education programs, and it can be used as a basic data for public oral health plan.