• 한국임상수의학회지
• /
• 제30권2호
• /
• pp.142-145
• /
• 2013

말운동신경세포질환은 척수와 뇌간에 존재하는 운동신경의 변성에 의해 자발적으로 발병하는 말의 신경성 질환이다. 8년령의 제주 조랑말 거세마 1두가 체중감소, 근육진전, 잦은 횡와, 낮은 두위, 발한, 사지를 모아 서있는 증상으로 내원하였다. 환마는 장기간 동일한 마방 내에서 초지 방목 없이 건초와 농후사료로 사육되었다. 혈청 생화학검사 결과 혈청 비타민 E(0.14 ${\mu}g/mL$; 정상 > 1.5 ${\mu}g/mL$)의 감소, CK(402 IU/L; 정상 119-287 IU/L) 및 AST(876 IU/L; 정상 226-336 IU/L)의 증가가 관찰되었다. 포도당 경구흡수시험에서는 부분적 흡수장애를 나타내었다. 미근부 근육생검 후 조직검사 결과 근섬유 위축과 비대, 핵 중심화, 변성 및 괴사된 근섬유가 관찰되었다. 상기의 내용을 종합하여 환마는 말운동신경세포질환으로 진단되었다. 경구 비타민 E 투여 5주 후, 환마는 정상적으로 개선된 기립자세와 두위, 횡와 빈도의 감소 및 체중증가를 보였다. 본 증례는 한국의 제주 조랑말에서 발생한 말운동신경세포질환으로서 비타민 E 치료에 성공한 최초의 보고이다.

• 한국임상수의학회지
• /
• 제38권5호
• /
• pp.225-230
• /
• 2021

A 4-year-old gelding Thoroughbred racehorse, which had been undergoing antibiotic therapy at a local veterinary clinic, was referred to the KRA veterinary center with a 20-day history of continuous right nasal discharge. Patient's history, endoscopic examination, and radiographic examination revealed primary maxillary sinusitis. Under sedation, surgical intervention was performed to collect samples and remove the accumulated mucopurulent exudate in the sinus. Swab samples were collected from the sinus during surgery for cytology and antimicrobial susceptibility testing. Only one type of bacteria was cultured, and molecular analyses of 16S ribosomal RNA gene sequences identified it as Staphylococcus aureus (S. aureus). The isolate was resistant to multiple antibiotics, which are frequently used in equine practice. Trimethoprim-sulfamethoxazole was chosen based on antibiotic susceptibility test, trephination, and sinus lavage using saline were applied to treat bacterial sinusitis. The clinical signs improved after 1 month and the patient resumed training. This report describes S. aureus isolated from bacterial maxillary sinusitis in a horse and its antibiotic susceptibility.

• 한국동물위생학회지
• /
• 제29권1호
• /
• pp.79-82
• /
• 2006

A 5 years old gelding (Thoroughbred, Equus caballus) had shown severe abdominal pain, colic, after overeating of hay in the feed storage. following through treatment, it subsequently died. Grossly, the large colon was impacted with firm mass of food and congestion of blood vessel in the intestinal wall. There were mild peritonitis and pleuropneumonia. This case demonstrates typical large colon impaction with hard consistence ingesta due to improper management of horse.

• Journal of Animal Science and Technology
• /
• 제50권6호
• /
• pp.741-746
• /
• 2008

본 연구는 한국마사회로부터 수집한 8,197두의 경주기록 총 155,656개를 이용하여 더러브렛 경주마의 체중변화가 주파기록에 미치는 효과를 구명하기 위하여 수행되었다. 국내 더러브렛 경주마의 평균 체중은 449kg 이었으며, 거세말, 수말과 암말의 평균 체중은 각각 460kg, 454kg과 441kg으로 수말의 체중이 가장 높게 나타났다. 암말의 경우 체중의 감소는 3월, 4월과 5월사이에 가장 크게 나타나며, 수말과 거세마의 경우 5월, 6월과 7월에 체중의 감소가 가장 크게 나타났다. 전반적으로 경주마의 체중은 봄과 여름에 감소하며, 가을과 겨울에 증가하는 현상을 나타내었다. 주파기록에 대한 유전력과 반복력은 각각 0.237과 0.525였으며, 체중에 대한 유전력은 0.612로 추정되었다. 직전 경주 대비 체중의 변화가 ±10kg 이상일 때 주파기록은 현저히 증가하였으며, 직전 경주 대비 체중의 변화가 ±20kg인 경우는 ±5kg인 경우와 비교했을 때 주파기록의 차이가 0.3초 정도 증가하였다. 체중의 변화가 체중에 비례하여 ±0.5% 정도 변화하였을 때 주파기록이 가장 우수하였으며, 체중의 변화가 체중 대비 ±2.5% 이상이 되면 경주능력은 현저히 감소하였다.

• 한국임상수의학회지
• /
• 제23권4권
• /
• pp.469-471
• /
• 2006

노책성 횡문근융해증의 재발을 보이는 거세된 4세령 Paint horse가 다당류저장성근질환으로 진단되었다. 말이 폐사하기전 보인 임상증상으로는 근약화, 근손실, 운동불내성, 장제시 사지를 들어올리는데 어려움이 있었고, grooming 시 민감한 반응, 이동 혹은 기립시 장애였다. 골격근 샘플의 조직검사를 통해서 말의 다당류저장성근질환으로 확진되었다.

• 한국임상수의학회지
• /
• 제38권1호
• /
• pp.41-44
• /
• 2021

Pituitary pars intermedia dysfunction (PPID), often referred to as equine Cushing's disease, is a common endocrine disorder often diagnosed in older horses. A 13-year-old 460 kg Warmblood gelding showed clinical signs suggestive of PPID, including hypertrichosis, fat redistribution, polyuria and polydipsia (PU/PD), and weight loss. Physical examination, complete blood cell count, and serum chemistry results were normal. However, dexamethasone suppression and plasma adrenocorticotropic hormone (ACTH) level tests confirmed PPID. Three months after the confirmed diagnosis, the horse was referred again with symptoms of laminitis. Radiography and venography were performed to evaluate the laminitis severity level. However, the foot condition continued to worsen, and the horse was eventually euthanized. The purpose of this case report is to describe clinical signs and diagnosis of PPID with laminitis.

• Mass Spectrometry Letters
• /
• 제14권3호
• /
• pp.104-109
• /
• 2023

Anabolic-androgenic steroids (AAS) are used illegally to enhance muscle development and increase strength and power. In this study, a reliable, and sensitive quantitative method was developed and validated using heptafluorobutyric acid anhydride (HFPA) derivatives for the simultaneous detection of prohibited AAS (testosterone [TS], boldenone [BD], 5α-estrane-3β,17α-diol [EAD]) using gas chromatography-tandem mass spectrometry (GC-MS/MS). For processing the samples, solid phase extraction, methanolic hydrolysis, and liquid-liquid extraction were used. For detection using mass spectrometry, the multiple reaction monitoring (MRM) mode was used with the electron ionization (EI) positive mode. The method was evaluated for selectivity, linearity, lower limit of quantification, intra- and inter-day precision, accuracy, and stability. The results showed that the method was accurate and reproducible for the quantitation of the three steroids. The developed method was finally applied to the analysis of a suspect gelding urine sample received from the Asian Quality Assurance Program (AQAP).

• 한국임상수의학회지
• /
• 제35권4호
• /
• pp.161-165
• /
• 2018

A 12-year-old gelding Warmblood Horse was presented with a corneolimbal mass in the right eye (OD) of 6 months duration. Clinical signs included ocular discomfort, persistent mucoid ocular discharge, and conjunctival hyperemia. The mass was excised by superficial keratectomy under sedation in a standing position, followed by a topical application of 0.04% mitomycin C (MMC), and a placement of a conjunctival advancement graft. The histopathological diagnosis was squamous cell carcinoma. One month after surgery, recurrence of the mass was suspected upon examination of the eye. Topical MMC and 5-fluorouracil followed by cryotherapy were applied as adjunctive therapies after debulking of the mass. The surgical site healed without complications and with a cosmetically acceptable result. No recurrence of the mass was noted four years following the second procedure.

• 한국임상수의학회지
• /
• 제24권3호
• /
• pp.473-475
• /
• 2007

A 11-year-old gelding Thoroughbred horse was presented with a history of unilateral nasal discharge of right side. The horse was diagnosed as maxillary sinusitis based on blood examination and radiography. The horse was treated with bone flap of right maxillary sinuses. Abscess of maxillary sinus was drained and irrigated with antibiotic-saline and povidone iodine solution. After surgical procedure, nebulization and medication applied by the result of antibiotic sensitivity test. After treatment for two weeks, the patient was recovered completely.

• 한국임상수의학회지
• /
• 제36권5호
• /
• pp.292-295
• /
• 2019

A 2-year-old, 440 kg, thoroughbred gelding showed a lameness grade of 3 out of 5, as well as swelling and heating on the proximal interphalangeal joint (PIPJ). Periarticular new bones due to the arthritis were observed on performing radiography and ultrasonography. PIPJ arthrodesis was performed under general anesthesia. With the PIPJ open, the articular cartilage was removed by using curette, chisel, and mallet. Arthrodesis was performed with a PIP plate and two additional transarticular cortex screws inserted in lag fashion. A cast was placed over the limb distal from the proximal metatarsal bone. At 6 months after surgery, complete union of the PIPJ was confirmed by radiography, and the incision site was well closed. Based on the outcome, a PIP plate with two additional transarticular cortex screws inserted in lag fashion is recommended as a method for treating osteoarthritis of the PIPJ in horses.