• Journal of Pharmaceutical Investigation
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• v.35 no.3
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• pp.151-155
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• 2005

A drug delivery system(DDS) for practically insoluble meloxicam was developed and evaluated by dissolution study. A novel DDS is two layered system, where the first layer is consisted of gas-forming agent for an immediate release and the second layer is composed of metolose SR(HPMC) for sustained release. This bilayered tablets were manufactured by using manual single punch machine. The results of dissolution study showed an initial burst release followed by sustained release for the experimental period time. From a pharmaceutical point of view, the designed DDS for meloxicam would be informative system in terms of poorly soluble analgesic medicines.

• 연구논문집
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• s.29
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• pp.49-55
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• 1999

Heat release rate used to characterize the fire is an important factor for determining the fire size, the fire growth and the time for suppression and evacuation. The purpose of present work is to review theoretical backgrounds and to introduce equations for estimation of heat release rate with oxygen consumption method in fires. Our work also shows the experimental results of applications for liquid fuels. The oxygen concentration is measured by the analyzer of paramagnetic type. The analyzers of Infra-Red type are used to measure the concentrations of $CO_2$ and CO gas. Time delays of analyzers are ignored.

• Transactions of the Korean Society of Automotive Engineers
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• v.4 no.1
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• pp.147-154
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• 1996

An one-zone heat release analysis was studied for a 6 cylinder direct injetction compressionignition engine. The heat transfer constants in this anlysis were calibrated to match the measured fuel energy at 1,000 rpm full load, which was the fuel mass multiplied by the fuel's heating value. The integrated gross heat release values were close to the measured fuel energy at various full load operating conditions. The combustion inefficiency from this calculation was proportional to the smoke of exhaust gas.

• Fire Protection Technology
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• s.19
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• pp.22-28
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• 1995

The rate of heat release is probably the single most important measure of fire hazard. Several tech-niques were developed for the measurement of rate of heat release, but were not suitable for fire test-ing purpose. Recently the application of oxygen consumption principle made it possible to development of well-characterized heat release rate measurement apparatus, the furniture calorimeter for large-scale fire tests and the cone calorimeter for bench-scale fire tests. The cone calorimeter can be used to determine the ignitability as well as heat release rate and smoke development, mass loss rate, combustion gas production etc. from burning materials. Thus, test method using cone calorimeter, an internationally recognized and accepted for the evalua-tion of fire properties, is a very promising tool for combustion study on various kind of materials and products.

• Fire Science and Engineering
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• v.33 no.3
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• pp.1-8
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• 2019

The international standard for FT-IR gas analysis of fire effluents in ISO 5660-1 cone calorimeter has been being developed in ISO TC 92. A comparison of the round-robin test of WD 21397 was conducted with six participating laboratories in 2018. The test specimens were PMMA, rigid PU foam board, and PVC flooring. The measurement quantities were the time-to-ignition, peak heat release rate, total heat release, and effective heat of combustion for a cone calorimeter test and peak gas concentration, gas generation, and gas yield for FT-IR gas analysis. No outliers were identified. For the cone calorimeter quantities, the repeatability and reproducibility were 1.5% and 9.8%, respectively. For FT-IR gas analysis, the repeatability and reproducibility was 12.9% and 27.9%, respectively.

• Korean Journal of Environmental Agriculture
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• v.42 no.2
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• pp.112-120
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• 2023

Methane (CH₄) and nitrous oxide (N₂O) are significant contributors to greenhouse gas (GHG) emissions from rice fields. Mid-summer drainage is a commonly practiced water management technique that reduces CH₄ emissions from rice fields. Slow-release fertilizers gradually release nutrients over an extended period and have been shown to reduce N₂O emissions. However, the combined effect of slow-release fertilizer and water management on GHG emissions remains unclear. This study compared GHG emissions from a rice paddy subjected to mid-summer drainage for 10 days (control) with that of a rice paddy subjected to prolonged mid-summer drainage for 20 days combined with slow-release fertilizer (W+S). Gas sampling was conducted weekly using a closed chamber method. During the rice cultivation period, cumulative CH₄ and N₂O emissions were reduced by 12.3% and 16.2%, respectively, in the W+S treatment compared to the control. Moreover, the W+S treatment exhibited a 1.9% increase in grain yield compared to the control. Under experimental conditions, slow-release fertilizers, in combination with prolonged mid-summer drainage, proved to be the optimal approach for achieving high crop yield while reducing GHG emissions. This represents an effective strategy to mitigate GHG emissions from rice paddy fields.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.5
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• pp.750-756
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• 2002

The effect of equivalence ratio and velocity on the stability of flame in dump combustor was studied in an atmospheric pressure, laboratory scathe dump combustor operating natural gas. Traditionally, peak-to-peak pressure, fluctuation of the heat release rate and Rayleigh index were used to find and control the combustion instability. Cross correlation coefficients, Ci,j which is defined as the normalized value of the integration of the product of two of the mixer pressure, dump plane pressure and heat release rate, are introduced to see whether the flame is stable or not. Ci,j shows more sensitive to combustion status than Rayleigh index in steadily burning flame. Also, the result indicates that the amplitude of Ci,j between heat release and mixer pressure goes up before the flame at the rich de-stabilizing equivalence ratio near $\psi$=0.85. t means Ci:j at this case has a potential to detect the de-stablizing moment in prior to becoming unstable in dump combustor.

• Journal of the Korean Wood Science and Technology
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• v.42 no.6
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• pp.675-681
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• 2014

The purpose of this study is to analyze fundamental combustion characteristics of woods used for indoor applications. The combustion characteristics such as heat release rate, total heat release, gas yield, and mass loss were analyzed by the method of cone calorimeter or thermogravimetry. These analysis results show that material properties of wood are closely related to flammability. It was shown that the relationship between the mass loss and gas emission. The results of combustion properties of woods would be useful for fundamentals of guiding the safe use of wood indoor application.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.32 no.8
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• pp.574-581
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• 2008

The characteristics of combustion and flow for a lean premixed flame in lab-scale gas turbine combustor was studied through experiment and numerical analysis. From the experiment, flame structure and heat release rate were obtained from OH emission spectroscopy. Qualitative comparisons were made line-integrated OH chemiluminescence image and abel-transformed one. NOx analyzer was implemented to get the characteristic of NOx exhaust from the combustor. From the numerical analysis, the thermal distribution and characteristic of recirculation zone with the change of fuel-air mixing degree, the characteristic of methane distribution with equivalence ratio in the combustor respectively. Total heat release rate is increased with increasing equivalence ratio. Thermal Nox is reduced with increasing fuel-air mixing degree. Increasing equivalence ratio results in the decrease of the size of reaction zone and alteration of the position of the reaction zone into the entrance of the combustor.

• Biomaterials and Biomechanics in Bioengineering
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• v.1 no.1
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• pp.13-25
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• 2014

In the current study, a drug-eluting stent coated with biodegradable polymers and sirolimus was developed by using an ultrasonic nanocoater and characterized in aspects of surface smoothness and coating thickness. In addition, in vitro release profiles of sirolimus by changing top coating layer with different biodegradable polymers were investigated. Smooth surfaces with variable thickness could be fabricated by optimizing polymer concentration, flow rate, nozzle-tip distance, gas pressure, various solvents and ultrasonic power. Smooth surface could be generated by using volatile solvents (acetone, chloroform, and methylene chloride) or post-treating with solvent vapor. Coating thickness could be controlled by varying injection volume or polymer concentration, and higher concentration could reduce the coating time while obtaining the same thickness. The thickness measurement was the most effectively performed by a conventional cutting method among three different methods that were investigated in this study. Release profiles of sirolimus were effectively controlled by changing polymers for top layer. PLGA made the release rate 3 times faster than PDLLA and PLLA and all top layers prevented burst release at the initial phase of profiles. Our results will provide useful and informative knowledge for developing drug-eluting stents, especially coated with biodegradable polymers.