• Biotechnology and Bioprocess Engineering:BBE
• /
• v.11 no.3
• /
• pp.230-234
• /
• 2006

In this study, we describe a one-step chemoenzymatic reaction for the production of natural blue pigments, in which the geniposide from Gardenia extracts is transformed by glycosidases to genipin. Genipin is then allowed to react with amino acids, thereby generating a natural blue pigment. The ${\beta}-glycosidases$, most notably Isolase (a variant of ${\beta}-glucanase$), recombinant ${\beta}-glycosidases$, Cellulase T, and amylases, were shown to hydrolyze geniposide to produce the desired pigments, whereas the ${\alpha}-glycosidases$ did not. Among the 20 tested amino acids, glycine and tyrosine were associated with the highest dye production yields. The optimal molar ratio of geniposide to glycine, two reactants relevant to pigment production, was unity The natural blue pigments produced in this study were used to dye cotton, silk, and wool. The color yields of the pigments were determined to be significantly higher than those of other natural dyes. Furthermore, the color fastness properties of these dyes were fairly good, even in the absence of mordant.

• Korean Journal of Pharmacognosy
• /
• v.25 no.4 s.99
• /
• pp.368-381
• /
• 1994

This study was attempted to investigate the effect of Gardeniae Fructus on GOT, GPT, Al.p, LDH activities and level of total cholesterol in serum of $CCl_{4}$ and $_{D}-galactosamine$ intoxicated rats, and bile excretion. The geniposide and extract caused a remarkabel decrease of GPT activities, level of total cholesterol in serum of $CCl_{4}$ intoxicated rats at EtOH Ex. 300, 500 mg/kg p.o., MeOH Ex. and geniposide 100 mg/kg p.o., and GOT, Al.p, LDH activities were significantly decreased compared with control group. It caused a remarkable decrese of GPT, Al.p, LDH activities in serum of $_{D}-galactosamine$ intoxicated rats, and GOT activities was significantly decreased compared with control group. The geniposide and extract caused a remarkable increase of bile excretion, when administration of EtOH extract 500 mg/kg p.o., MeOH extract 100 mg/kg i.d., MeOH extract 50 mg and geniposide 50 mg/kg i. v. compared with normal-control group.

• The Journal of Internal Korean Medicine
• /
• v.40 no.6
• /
• pp.1294-1302
• /
• 2019

Objective: Glucagon-like peptide 1 (GLP-1), one of the gut peptide hormones, has an action to induce satiety, and its effect as an anti-obesity agent is known. Recently, it has been reported that many herbal medicines have an anti-diabetic effect through inhibition of DPP-4 enzyme and inducing of GLP-1 secretion. It is therefore suggested that GLP-1 may be effective for the treatment of obesity. In this study, we report a case of male obese patients treated with herbal medicine as a GLP-1 secretagogue. Methods: In this study, the patient took a fixed prescription of herbal medicine for 10 weeks and recorded his weight at each visit. Results: This prescription produced significant weight loss (BMI loss>5%). In the follow-up period after two weeks, the trend of weight loss was observed continuously. Conclusion: This prescription can be an alternative to ephedra herba-based obesity treatment.

• Journal of the Korea Fashion and Costume Design Association
• /
• v.17 no.2
• /
• pp.45-61
• /
• 2015

In order to analysis on color difference of natural dyes, I have dyed Hanji, cotton, silk fabric and exposed them to carbon arc light. The results of experiment have been analysed by wavelength of maximum absorption, amounts of dye uptake, color difference, Hunter's value and Munsell's value. Gardenia Jasminoides is monogenetic dye, but it gained darker color by pre-mordanting method used Al mordant agent and greenish yellow color by Fe mordant agent. whereas Curcuma, an Amur cork, and bud of pagoda tree are shown as greenish yellow color, and A barberry root, Betel nut, and Rhubarb are shown as reddish yellow color. these gained khaki colored dyed fabric by Fe mordanting. In addition, Sappan wood showed great result in pre-mordanting. Especially, it gained dark red color by Al pre-mordanting. The pink color was shown by post-mordanting. and Logwood showed great dyeing result in Hanji and cotton better than silk. Specially pre-mordanting was effective. Hanji and cotton showed greenish blue color by Al pre-mordanting, and silk showed brown color.

• Journal of the Korea Fashion and Costume Design Association
• /
• v.18 no.4
• /
• pp.77-86
• /
• 2016

In order to analysis on color difference of natural dyes, I have dyed Hanji, cotton, silk fabric and exposed them to carbon arc light. The results of experiment have been analysed by Munsell's value, and compared the difference of colors which were recognized visually. Gardenia Jasminoides is monogenetic dye, but it gained darker color by pre-mordanting method used aluminum mordant agent and greenish yellow color by ferric mordant agent. whereas Curcuma, an Amur cork, and bud of pagoda tree are shown as greenish yellow color, and A barberry root, Betel nut, and Rhubarb are shown as reddish yellow color. these gained khaki colored dyed fabric by ferric mordanting. In addition, Sappan wood showed great result in pre-mordanting. Especially, it gained dark red color by aluminum pre-mordanting. The pink color was shown by post-mordanting. and Logwood showed great dyeing result in Hanji and cotton better than silk. Specially pre-mordanting was effective. Hanji and cotton showed greenish blue color by aluminum pre-mordanting, and silk showed brown color. However the color, which was recognized visually, differed from colorimeter sometimes. Therefore, such color table might be necessary for the natural dyeing.

• Journal of Conservation Science
• /
• v.34 no.2
• /
• pp.129-135
• /
• 2018

Scientific investigation of cultural heritage can provide important information to understand the context of the object. To know the characteristics of the material is also an essential part of objects management and conservation. However, the identification and characterization of organic dyes used in archaeological and historical textiles are often limited by the restrictions in sampling. To cope with the difficulties, applications of high-performance techniques of surface analysis, such as Time of Flight-Secondary Ion Mass Spectra (TOF-SIMS) could be considered as a non or micro-destructive option. This study aims to examine the applicability of TOF-SIMS analysis to the detection of organic dyes from historical textiles. A group of silk fabrics dyed with vegetable dyes were artificially photo-aged to different degrees and analyzed with TOF-SIMS. Molecular and fragment ions from indigo were successfully detected from the aged samples; however, only some fragment ions were observed from gardenia and safflower dyed fabrics. Further studies with actual historical samples with extended examination scope would be necessary to assess the validity of this technique.

• Journal of the Korean Institute of Landscape Architecture
• /
• v.18 no.3 s.39
• /
• pp.1-9
• /
• 1990

Landscape plants as attenuator of vehicular noise were basically experimented with 8 kinds of trees and shrubs at the university nursery, and checked the attenuating effects by the planted distances, species and sound frequencies. The experimental results are shown and sumarized as follows ; 1. Most plants showed the considerable noise attenuating function in the sound frequencies of 63Hz and 1,000Hz. Tall trees such as Juniperus chinensis var. kaizuka and Magnolia grandiflora showed better effects than shrubs or small trees such as Gardenia jasminoides, Osmanthus fragnance, Osmanthrs heterophyllus, Rhododendron indicum, Chamaecyparis obtusa 'Tetragona Aurea' and Pinus paruiflora in 63Hz frequency, but shrubs showed better effects in 1,000Hz. 2. Trees showed 6~8dB attenuation and shrubs 4~5dB regardless an increase of distance between sound source and receiver in 63Hz. 10 meter width of tree belt could reduce 10 more dB, but 5 meter of shrub belt showed the same effect in 1,000Hz. 3. Trees having more leaves and wider crown showed constantly increase of attenuation of sound by the distance in 1,000Hz, and distinct increase of attenuation were observed in 2,000 more Hz.

• International Journal of Oral Biology
• /
• v.36 no.4
• /
• pp.187-194
• /
• 2011

Periodontitis is an inflammatory disorder of the periodontium, characterized by destruction of the tooth supporting tissues including alveolar bone and mediated by various pro-inflammatory mediators. Here, we demonstrated that HP08-0106, composed of four crude drugs-Gardenia jasminoides Grandiflora, Angelica gigas Nakai, Rehmannia glutinosa, and Schizonepeta tenuifolia in a weight ratio of 2:2:1:2, perturbs inflammatory responses, osteoclast formation in LPS-induced RAW 264.7 cells and alveolar bone resorption in ligature-induced periodontitis. HP08-0106 decreased the protein level of iNOS and COX2 as well as the secreted level of IL-$1{\beta}$, indicating that HP08-0106 has antiinflammatory effects. HP08-0106 also inhibited the expression of genes associated with osteoclastogenesis including c-Fos, MMP-9 and TRAP. Moreover, HP08-0106 exhibited a protective effect from alveolar bone loss in ligature-induced periodontitis animal models. Our results strongly suggest that HP08-0106 represent an important therapeutic tool to treat inflammatory disorders associated with bone loss such as periodontitis.

• The Korean Journal of Ecology
• /
• v.5 no.4
• /
• pp.164-175
• /
• 1982

This paper contains the results obtained by the ecological investigation in Bijin island. The investigation was conducted during 3 dyas from Aug. 3 to Aug. 5, 1981. The results are followings. The tracheophyta of this island was recoreded as 64 families, 128 genera, 142 species, 21 varieties and 2 forma. Twenty eight species of ever-green broad-leaved trees comprising Gardenia jasminoides for. grandiflora, Castanopsis cuspidata var. thunbergii, Camellia japonica, etc. wad distributed in the southern area of the island. And there was the wind-break forest mainly consisting of aged Machilus thunbergii, Celtis sinensis and Zelkova serrata in the northern area. The northern area dominated by the second forest of Pinus thunbergii, where the whole residents lead their lives, shows the high population density and pure farming rate, so the natural degree is low. The other hand, there was the well-preserved forest of broad-leaved trees containing Zelkoba serrata. Acer palmatum and Quercus serrata, etc. in southern area having a steep peak, Seonyudai, and no resident. So, the potential vegetation of this island is assumed as the forest of ever-green broad-leaved trees which belongs to the forest of subtropics.

• Textile Coloration and Finishing
• /
• v.24 no.4
• /
• pp.270-280
• /
• 2012

This study examined the dyeing characteristics of five oriental herbs, namely Gardenia jasminoides, Sophora japonica L., Rheum coreanum, Rhus javanica L., Ginkgo biloba L., on fabrics with traditional fermentation using malt. And the properties of Hwangsu (mineral water) of Yeongcheon (Korea)as a mordant in the post-treatment of textile were evaluated. The dyeability and fastness of cotton fabric and silk to light and washing as well as different fermentation periods and temperatures were investigated, and the following results were obtained. The dyeability of the fermented and non-fermented material did not show a significant difference. Fabrics mordanted with Hwangsu generally exhibited a reddish color due to the presence of iron. The dyeing of cotton fabric and silk by fermentation and Hwangsu mordanting were found to be effective on Rhus javanica L. and Rheum coreanum. These results were confirmed through fastness to light 3 of cotton on Rheum coreanum and 3-4 of silk on Rhus javanica L., respectively. The washing fastness of both fabrics dyed with fermented Rhus javanica L. and Rheum coreanum was improved, showing higher K/S value after washing than before washing.