• East Asian Economic Review
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• 제18권2호
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• pp.111-142
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• 2014

We examine whether country fundamentals help explain the cross-section of currency excess returns. For this purpose, we consider fundamental variables such as default risk, foreign exchange rate regime, capital control as well as interest rate in the multi-factor model framework. Our empirical results show that fundamental factors explain a large part of the cross-section of currency excess returns. The zero-intercept restriction of the factor model is not rejected for most currencies. They also reveal that our factor model with country fundamentals performs better than a factor model with usual investment-style factors. Our main empirical results are based on 2001-2010 balanced panel data of 19 major currencies. This paper may fill the gap between country fundamentals and practitioners' strategies on currency investment.

• Environmental Analysis Health and Toxicology
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• 제23권4호
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• pp.231-245
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• 2008

Various methods for detecting changes in response behaviors of indicator specimens are presented for monitoring effects of toxic treatments. The movement patterns of individuals are quantitatively characterized by statistical (i.e., ANOVA, multivariate analysis) and computational (i.e., fractal dimension, Fourier transform) methods. Extraction of information in complex behavioral data is further illustrated by techniques in ecological informatics. Multi-Layer Perceptron and Self-Organizing Map are applied for detection and patterning of response behaviors of indicator specimens. The recent techniques of Wavelet analysis and line detection by Recurrent Self-Organizing Map are additionally discussed as an efficient tool for checking time-series movement data. Behavioral monitoring could be established as new methodology in integrative ecological assessment, tilling the gap between large-scale (e.g., community structure) and small-scale (e.g., molecular response) measurements.

• 정보보호학회논문지
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• 제6권4호
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• pp.53-66
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• 1996

World Wide Web is a total solution for multi-media data transmission on Internet. Because of its characteristics like ease of use, support for multi-media data and smart graphic user interface, WWW has extended to cover all kinds of applications. The Secure Information Center(SIC) is a data transmission system using conventional cryptography between client and server on WWW. It's main function is to support the encryption of sending data. For encryption of data IDEA(International Data Encryption Algorithm) is used and for authentication mechanism MD5 hash function is used. Since Secure Information Center is used by many users, conventional cryptosystem is efficient in managing their secure interactions. However, there are some restrictions on sharing of same key and data transmission between client and server, for example the risk of key exposure and the difficulty of key sharing mechanisms. To solve these problems, the Secure Information Center provides encryption mechanisms and key management policies.

• IMMUNE NETWORK
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• 제21권1호
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• pp.7.1-7.24
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• 2021

The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 has severely impacted global health and economy. There is currently no effective approved treatment for COVID-19; although vaccines have been granted emergency use authorization in several countries, they are currently only administered to high-risk individuals, thereby leaving a gap in virus control measures. The scientific and clinical communities and drug manufacturers have collaborated to speed up the discovery of potential therapies for COVID-19 by taking advantage of currently approved drugs as well as investigatory agents in clinical trials. In this review, we stratified some of these candidates based on their potential targets in the progression of COVID-19 and discuss some of the results of ongoing clinical evaluations.

• 한국농림기상학회지
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• 제24권4호
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• pp.234-243
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• 2022

우리나라에서 우박에 의한 피해는 매년 발생하고 있으며, 특히 농업 분야의 경우 노지 작물과 재배 시설에 치명적인 손실을 입히고 있다. 이러한 우박 피해를 최소화하기 위해 국내 주산지 분포와 작물 생육에 맞춤화 된 우박정보 서비스 시스템의 개발이 필요하다. 그러나 우박의 관측은 다른 기상 변수에 비해 상대적으로 많은 어려움이 따르고 자료도 시공간적으로 불균일성이 크며 산발적이다. 이에 본 연구는 우박정보 서비스 시스템 개발의 일환으로 우박 발생에 대한 시·공간 분포를 파악하기 위해 자연과학적 자료인 기상청 목측자료와 사회과학적 자료인 신문기사 자료를 통합한 우박 관측 DB를 구축하고, 이를 기반으로 우박위험지도를 제작하였다. 이러한 다학제적 우박 자료 융합을 통해 우박 자료의 공백기간과 공백지역에 대해서 보완이 될 수 있었다. 지역별 우박 발생 시기와 빈도 및 크기에 대해 분석한 결과, 최근으로 올수록 크기가 큰 우박의 비중이 증가하였고, 발생 시간은 상승기류가 잘 형성되는 오후 시간대에 주로 분포하였다. 강원, 경북, 충북 등 남한의 북동쪽과 일부 내륙 지역이 더 자주 발생하였고, 겨울에는 북쪽 해안과 일부 내륙 지역에 주로 싸락 우박이 발생하였다. 통합 자료를 이용하여 제작한 우박 위험지도를 통해 1970~2018년 기간의 전국적인 발생 분포 특성과 극값들이 제시되었다. 이번 연구에서 제작된 우박위험지도는 작물 재배적지 선정과 생육 관리에 다학제적인 응용기후 자료로서 도움을 줄 것이다.

• The Korean Journal of Pain
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• 제27권4호
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• pp.321-325
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• 2014

Background: Epidural blocks are widely used for the management of acute and chronic pain. The technique of loss of resistance is frequently adopted to determine the epidural space. A discontinuity of the ligamentum flavum may increase the risk of failure to identify the epidural space. The purpose of this study was to investigate the anatomic variations of the cervical and high thoracic ligamentum flavum in embalmed cadavers. Methods: Vertebral column specimens of 15 human cadavers were obtained. After vertebral arches were detached from pedicles, the dural sac and epidural connective tissue were removed. The ligamentum flavum from C3 to T6 was directly examined anteriorly. Results: The incidence of midline gaps in the ligamentum flavum was 87%-100% between C3 and T2. The incidence decreased below this level and was the lowest at T4-T5 (8%). Among the levels with a gap, the location of a gap in the caudal third of the ligamentum flavum was more frequent than in the middle or cephalic portion of the ligamentum flavum. Conclusions: The cervical and high thoracic ligamentum flavum frequently has midline intervals with various features, especially in the caudal portion of the intervertebral space. Therefore, the ligamentum flavum is not always reliable as a perceptible barrier to identify the epidural space at these vertebral levels. Additionally, it may be more useful to insert the needle into the cephalic portion of the intervertebral space than in the caudal portion.

• 한국지역사회생활과학회지
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• 제17권3호
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• pp.55-65
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• 2006

Recent trends of global food production, processing, distribution and preparation under free trade circumstance are creating an increase in common' concerns about food safety. It is important that farmers improve agricultural products/food safety for satisfying consumer needs and health. Cognizant to the situation, this study was conducted to analyze how the Producers gather information, and determine their awareness about agricultural Products safety using a safety Questionnaire. The Questionnaire was given to 500 farmers who cultivate rice, fruit trees, vegetables, and other crops from September through October 2005. More than half of the producers felt concerns about the agricultural products/foods safety. Uneasiness of the producers was higher amongst those who were younger and earned a higher income. Pesticides and zoonosis (BSE AI, etc.) emerged as the main risk factors causing concerns among the greatest number of producers. Producers had a positive opinion of the effects and perception of food safety, but no opinion of the activity of government. The producers showed a high level of understanding of the Country of Origin Labeling System (88.2%), the quality certification system of agricultural and livestock products (71.9%), and the raising system of environment-friendly agriculture (72.7%). However, their level of understanding of the GAP (59.3%) and the Traceability System (22.8%) was still low. To effectively implement these policies, awareness of producers who are the beneficiaries of the above policies has to be enhanced. Therefore, the safety information should be provided at a more appropriate time and should be easier to understand.

• Journal of Construction Engineering and Project Management
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• 제6권2호
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• pp.1-7
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• 2016

Construction in the UK is the second most dangerous industry in terms of fatal and minor injuries according to the 2014 report of HSE. The use of mobile devices such as iPad, Tablets and Smart phones on the live construction projects is also on the increase in the UK due to the 2016 - Level 2 BIM (Building Information Modelling) implementation target, set by the UK Government. Hence, the use of such devices may become a distraction from work activities on the construction sites and will cause a major risk to the end users. The subject of improving safety of BIM use is widely researched, but there is a gap in knowledge about the actual use of the mobile devices and perception of 'Site BIM', on the construction site activities. The main gap identified in the 'Site BIM' is the health and safety aspect of using such devices on the construction sites. A safer way of working with such devices needs to be identified to avoid any potential site hazards and fatalities before the widespread use of the devices are found on the construction projects. In that context, the paper is aimed to highlight the safety issues that are required to address for the successful implementation of the mobile devices for safer use of the 'Site BIM'. Questionnaire survey was used to collect the site information among construction professionals in the UK. The survey findings suggested that a proactive approach may be helpful to stop potential hazards and risks causing by the use of mobile devices and potential measures need to be identified before any injuries and incidents occur. The paper concludes that training, changing size of mobile devices and ensuring a separate induction training for 'Site BIM' tools will improve the health and safety of the end users of the mobile devices at the live construction sites.

• 한국지하수토양환경학회지:지하수토양환경
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• 제27권spc호
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• pp.64-74
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• 2022

The conceptual site model (CSM) is used as a key tool to support decision making in risk based management of contaminated sites. In this work, CSM was applied in Jeonju Industrial Complex where site investigation for groundwater contamination was conducted. Site background information including facility types, physical conditions, contaminants spill history, receptor exposure, and ecological information were collected and cross-checked with tabulated checklist necessary for CSM application. The CSM for contaminants migration utilized DNAPL transport model and narrative CSMs were constructed for source to receptor pathway, ecological exposure route, and contaminants fate and transport in the form of a diagram or flowchart. The component and uncertainty of preliminary CSM were reviewed using the data gap analysis while taking into account the purpose of the survey and the site management stage at the time of the survey. Through this approach, the potential utility of CSM was demonstrated in the site management process, such as assessing site conditions and planning follow-up survey work.

• 한국환경성돌연변이발암원학회지
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• 제23권2호
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• pp.56-62
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• 2003

The liver progenitor cells could form a potential target cell population fore both tumor-initiating and -promoting chemicals. Induction of drug-metabolizing and antioxidant enzymes, including AhR-dependent CYP1A1, NQO-1 and AKR1C9, was detected in the rat liver epithelial WB-F344 "stem-like" cells. Additionally, WB-F344 cells express a functional, wild-type form of p53 protein, a biomarker of genotoxic events, and connexin 43, a basic structural unit of gap junctions forming an important type of intercellular communication. In this cellular model, two complementary assays have been established for detection of the modes of action associated with tumor promotion: inhibition of gap junctional intercellular communication (GJIC) and proliferative activity in confluent cells. We found that the PAHs and PCBs, which are AhR agonists, released WB-F344 cells from contact inhibition, increasing both DNA synthesis and cell numbers. Genotoxic effects of some PAHs that lead to apoptosis and cell cycle delay might interfere with the proliferative activity of PAHs. Contrary to that, the nongenotoxic low-molecular-weight PAHs and non-dioxin-like PCB congeners, abundant in the environment, did not significantly affect cell cycle and cell proliferation; however both groups of compounds inhibited GJIC in WB-F344 cells. The release from contact inhibiton by a mechanism that possibly involves the AhR activation, inhibition of GJIC and genotoxic events induced by environmental contaminants are three important modes of action that could play an important role in carcinogenic effects of toxic compounds. The relative potencies to inhibit GJIC, to induce AhR-mediated activity, and to release cells from contact inhibition were determined for a large series of PAHs and PCBs and their metabolites. In vitro bioassays based on detection of events on cellular level (deregulation of GJIC and/or proliferation) or determination of receptor-mediated activities in both ?$stem-like^{\circ}{\times}$ and hepatocyte-like liver cellular models are valuable tools for detection of modes of action of polyaromatic hydrocarbons. They may serve, together with concentration data, as a first step in their risk assessment.