• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.8
• /
• pp.3233-3239
• /
• 2015

Background: Whether depression causes increased risk of the development of breast cancer has long been debated. We conducted an updated meta-analysis of cohort studies to assess the association between depression and risk of breast cancer. Materials and Methods: Relevant literature was searched from Medline, Embase, Web of Science (up to April 2014) as well as manual searches of reference lists of selected publications. Cohort studies on the association between depression and breast cancer were included. Data abstraction and quality assessment were conducted independently by two authors. Random-effect model was used to compute the pooled risk estimate. Visual inspection of a funnel plot, Begg rank correlation test and Egger linear regression test were used to evaluate the publication bias. Results: We identified eleven cohort studies (182,241 participants, 2,353 cases) with a follow-up duration ranging from 5 to 38 years. The pooled adjusted RR was 1.13(95% CI: 0.94 to 1.36; $I^2=67.2%$, p=0.001). The association between the risk of breast cancer and depression was consistent across subgroups. Visual inspection of funnel plot and Begg's and Egger's tests indicated no evidence of publication bias. Regarding limitations, a one-time assessment of depression with no measure of duration weakens the test of hypothesis. In addition, 8 different scales were used for the measurement of depression, potentially adding to the multiple conceptual problems concerned with the definition of depression. Conclusions: Available epidemiological evidence is insufficient to support a positive association between depression and breast cancer.

• CELLMED
• /
• v.2 no.2
• /
• pp.16.1-16.5
• /
• 2012

Fever in cancer patients is often due to the following causes: evil qi and toxity stagnancy, disorders of qi and blood, deficiencies of zang and fu organs, and the disorder of yin and yang. The treatments given to cancer patients with a fever are according to five: (a) Excessive inner heat and toxicants: remove heat and the toxicant, induce purgation. We use Cheng-Qi-Tang plus Qing-Wen-Bai-Du-Yin. (b) Tangle of damp and heat, and qi stagnancy: remove damp and heat, smooth the qi channel. We use Gan-Lu-Xiao-Du-Dan or San-Ren-Tang. (c) Obvious blood and heat stagnancy: remove heat and blood stasis. We use Xue-Fu- Zhu-Yu-Tang. (d) Deficiency of spleen qi, inner heat caused by a yin deficiency: nourish spleen qi and yin to remove the inner heat. We use Bu-Zhong-Yi-Qi-Tang or Xiao-Jian-Zhong-Tang. (e) Prominent yin deficiency and hectic fever: replenish yin and remove inner heat. We use Qing-Hao-Bie-Jia-Tang or Chai- Qian-Mei-Lian-San. The pathogenesis of fever in cancer patients is complicated. We can see both deficiency and excess in one differentiation. Therefore, we must make sure of it, then we can get the most effective treatment.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.14
• /
• pp.5861-5865
• /
• 2014

High risk forms of the human papilloma virus (HPV) are generally accepted as necessary causative agents for cervical cancer. Recently, a possible relation between HPV and oral squamous cell carcinoma (OSCC) has also been noticed. The present study was conducted to investigate the prevalence of HPV infection in OSCCs in Wuhan city. DNA samples were collected from fresh tissues in 200 patients with OSCC and 68 normal controls. The polymerase chain reaction and direct sequencing were used to identify the HPV types in the samples. The prevalence of HPV of all types in the OSCC group was higher than in the control group (55/200 vs 2/68, OR=11.5, 95% CI=2.6-50.2). HPV16 and HPV18 were the main types detected, with HPV6 was the only low-risk type identified. High-risk HPV types HPV16 and HPV18 are prevalent in OSCC patients and may participate in the development of OSCC with traditional risk factors, tobacco and alcohol, possibly exerting synergistic effects. The results of multinomial logistic regression showed that those who smoked, consumed alcohol and with HPV infection have the highest risk of developing oral cancer (OR=13.3, 95% CI=3.1-56.8). Adjusted for age, smoking and alcohol use, HPV infection was independently associated with oral squamous cell carcinoma.

• Journal of Korean Medical classics
• /
• v.19 no.1 s.32
• /
• pp.1-15
• /
• 2006

UNGI(運氣) theory is one of the most important theory in Oriental medicine. But it's so difficult to adapt to real medic. Long time ago many Oriental Physicians disscussed this with other physicians, UNGI to Oriental Medicine, and so still now. Remarkably, it is important as a basic theory itself, UNGI exist as a special medic. We can see that in the book of ‘五運六氣韓醫學寶鑑’, ‘運氣演繹方藥篇’ and other such kind of books. The special thing is we can predict each man's disease through the date of his birth. And more, we can make out prescription for each person's health. In addition, by knowing his date of birth, we can calculate his date of pregnancy, and with the same way, we can also predict and prescript that he can be protected from his fateful disease. But, the way like this can make Oriental medic an astrology and a superstition. So I studied on this and concluded as follow, 1. UNGI theory is important in the Oriental Medicine not only in basic but on diagnosis and attendance. 2. Mechanical abuse in the past, make UNGI theory unbelievable. But Liu Ha-gan(劉河間) studied so deeply, and knew the right way to applicate UNGI theory on Oriental medic. 3. It is not logical the pregnant day counted thru birthday, so we have to percept this an abstract idea. And it founded detail way to count the pregnant day. 'UNGI' as a medical system, by knowing his birthday we can predict and prevent his fateful disease. Of course, I cannot find such substances in Neijing, and classic books on Oriental medicine. So queer at a glance, but clinically it has some valuable meanings. However, There's little to prove its foundation. It is similar to astrology, we cannot define its base. The problems we have to trace and find out.

• Journal of IKEEE
• /
• v.24 no.3
• /
• pp.791-796
• /
• 2020

In this paper, "Q-Bone", a 3^rd generation blockchain platform with enhanced security and flexibility, was developed. As a 3^rd generation blockchain platform, it exploits BP (block producer) to increase processing speed. It has many advantages as follows. It improves both security and speed by mixing RSA (Rivest-Shamir-Adleman) and AES (advanced encryption standard). It improves flexibility by exploiting gateway to convert between apps and blockchain with different programming language. It increases processing speed by combining whole transactions into one block and distribute it when too many transactions occur. It improves search speed by inserting sequence hash into transaction data. It was implemented and applied to pet communication service and academy-instructor-student matching service, and it was verified to work correctly and effectively. Its processing speed is 3,357 transactions/second, which shows excellent performance.

• Korean Institute of Interior Design Journal
• /
• v.22 no.5
• /
• pp.225-232
• /
• 2013

The spatial separation of male's and female's area due to the law of 'Naeoei' is one of the trademark features of residence by the building principle of 'Confucianism' in the upper class house in the late of the Chosun Dynasty. Thanks to modernized agriculture and commerce, the residence of 'Sinheung-Yangban' developed. And they were influenced by the economic and living characteristics than traditional custom. So the residence of 'Sinheung-Yangban' is very important in terms of the course of modernizing of the korean traditional residence. Researcher figures out the influences of the law of 'Naeoei' in residence and the characteristics of male's and female's field in terms of daily life with investigating the residence of 'Sinheung-Yangban' as the upper class house in the late of the Chosun Dynasty. Through this, the goal of this study is to find the properties of male's and female's field of upper class houses in the late of the Chosun Dynasty. With this study, the followings are the characteristics of male's and female's spatial composition of upper class houses in Gyong-gi Province in the late of the Chosun Dynasty. First, the traditional law of 'Naeoei' plays a primary role as the principle of building of upper class houses in Gyong-gi Province in the late of the Chosun Dynasty. With a natural result, there is a clear spatial separation as the male's and female's social role. Second, 'An-Chae' and 'Sarang-Chae' as male's and female's living space are separated physically, but real living life tends to be syntagmatically made with 'An-Madang' as the center. Third, spatial integration of 'An-Madang' as the center results in the development of architectural connection factors of 'An-Chae' and 'BaKat-Chae' adjoining 'An-Madang', facing 'Toei-Gan', 'Maru', and 'door'. Forth, the boundary of male's and female's areas is relatively clear between dwellers and visitors, but on the other hand, the separation of male's and female's spaces between family members has little significance.

• The Journal of Pediatrics of Korean Medicine
• /
• v.24 no.1
• /
• pp.104-116
• /
• 2010

Objectives The Medical record consist of symptoms, the cause of a disease, diagnostic studies, medical treatment, prescription, and so on. Doctors can use medical records as data for diagnosis, treatment, and education. Therefore, medical records are beneficial. Methods Translating $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ into modern Korean, and studying the medical records of Qian Yi(錢乙)'s Medical concept in $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ were examined. Results Regarding the diagnosis of the pediatric diseases, Si Zhen He Can(四該合參), consider in the eye exam closely. In addition, he closely combined the concept of Wu Zang Bian Zheng(五藏辨證), and diagnosis the pediatric diseases. Wu Zang Bian Zheng(五藏辨證). what Qian-Yi(錢乙) established method was based on Zheng Ti Guan(整體觀) in Huang Di Nei Jing(黃帝內經). Qian-Yi(錢乙) took a close look on Chuang Zhen(瘡疹) which had been an inadequate field in those days. He criticized on the habitual misuse of medications. He treated Ji Jing(急驚) and Man Jing(慢驚) separately; Ji Jing(急驚) as Liang Xie(凉瀉) and Man Jing(慢驚) as Wen Bu(溫補). He proposed Zong Gan Zhu Feng and Xin Zhu Jing(縱肝主風, 心主驚) theory and formulated Jing Feng(驚風) theory as well. He emphasized the treatment to Gong Bu Shang Zheng, Bu Bu Zhi Xie, Xiao Bu Jian Shi(攻不傷正, 補不滯邪, 消補兼施) because he had a clear demonstration to Han Re Xu Shi(寒熱虛實) of the five viscera in the field of Fang yao(方藥). Conclusions Understanding $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ and its medical records of Qian Yi(錢乙)'s medical concept had quintessential meaning to both modern pediatrician and oriental medical doctors of all medical fields in treating children.

• The Journal of Korean Physical Therapy
• /
• v.24 no.2
• /
• pp.143-150
• /
• 2012

Purpose: This study was intended to discover the effect of the turning training on figure of 8 tract on stroke patients' static and dynamic balance, as well as walking. Methods: A total of 42 stroke patients participated in this study. The training group was trained on the figure of 8 tract, while the control group was trained on the straight path for 30 minutes per day, for 4 weeks. Berg balance scale was used to measure the balance of the patients, before and after the training, and Good balance system was used to measure the sway speed and the distance of COG while standing. To measure the ability of walking, TUG and FSST were also used. Results: There were significant increases in the average score of Berg balance scale, in both groups after the training, and also significant difference between both groups were observed. The training group showed significant differences in the static balance ability, as well as anteroposterior and mediolateral sway speed. Further, there were significant increases in the dynamic balance ability, COP total distance, and TUG in both groups. The results showed more differences in comparing the control group with that of the training group. In FSST, there was no change in the control group, but there was a significant increase in the training group. Conclusion: Turning training on figure of 8 tract in stroke patients significantly increased the static and dynamic balance and walking ability. Based on the results, it can be seen that the training on the figure of 8 tract can influence the ability of balance and walking, which can lead to appropriate reactions to the change of environment and various tasks. Thus, it is assumed that turning training on figure of 8 tract as a means of improving the condition of stroke patients can be a meaningful program.

• Journal of Veterinary Clinics
• /
• v.23 no.2
• /
• pp.102-104
• /
• 2006

The purpose of this study was to document the histology of canine acupoints. Acupunctural needles were inserted by 0.5 to 1 cm depth into acupoints Nei-guan (Inner pass, PC06), Gan-shu (Liver Association Point, BL18), Shen-shu (Kidney Association Point, BL23) and Pangguang-shu (Bladder Association Point, BL28) in 4 dogs, and the tissues around the acupoints were examined. Light microscopy was used to observe the surrounding structures of each point. Nerve fibres, small vessels and muscle spindles were found around the tip of the needle in every case, although they occurred not so often at nonacupoint in nearby region or nonacupoint in the areas, such as skin, subcutaneous tissue and muscle. Therefore, it is suggested that nerve fibres, small vessels and muscle spindles may be potential acupoint receptors.

• The Journal of Korea Robotics Society
• /
• v.13 no.1
• /
• pp.26-30
• /
• 2018

Planetary global localization is necessary for long-range rover missions in which communication with command center operator is throttled due to the long distance. There has been number of researches that address this problem by exploiting and matching rover surroundings with global digital elevation maps (DEM). Using conventional methods for matching, however, is challenging due to artifacts in both DEM rendered images, and/or rover 2D images caused by DEM low resolution, rover image illumination variations and small terrain features. In this work, we use train CNN discriminator to match rover 2D image with DEM rendered images using conditional Generative Adversarial Network architecture (cGAN). We then use this discriminator to search an uncertainty bound given by visual odometry (VO) error bound to estimate rover optimal location and orientation. We demonstrate our network capability to learn to translate rover image into DEM simulated image and match them using Devon Island dataset. The experimental results show that our proposed approach achieves ~74% mean average precision.