• Title/Summary/Keyword: Gamma shift

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Upregulation of IP-10(CXCL10) mRNA Expression by Interleukin-18

  • Kim, Hyo-Young;Kim, Hee-Sun
    • Journal of Yeungnam Medical Science
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    • v.24 no.1
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    • pp.67-78
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    • 2007
  • Background : Interleukin-18 (IL-18) is one of the principal inducers of interferon-${\gamma}$ (IFN-${\gamma}$) in lymphocytes. Materials and Methods : The effect of IL-18 on the expression of chemokine IP-10(CXCL10) mRNA in C57BL/6 mouse peritoneal macrophages was studied by using Northern blot analysis, enzyme linked immunosobent assay and electrophoretic mobility shift assay. Results : IL-18 was determined to exert no direct effect on the expression of IP-10(CXCL10) mRNA. However, IL-18 pretreatment was determined to play a cooperative role in the synergistic induction of LPS-induced IP-10(CXCL10) mRNA expression. The effect associated with IL-18 pretreatment with regard to the synergistic induction of LPS-induced IP-10 (CXCL10) mRNA expression was detected after 16 hr of IL-18 pretreatment, administered prior to LPS stimulation. The pattern of NF-${\kappa}B$ binding activity during IL-18 pretreatment with LPS stimulation was found to coincide with the expression of IP-10(CXCL10) mRNA. Conclusion : Although IL-18 alone exerts no direct effect on the expression of chemokine IP-10(CXCL10), a definite period of IL-18 pretreatment induces the synergistic expression of LPS-induced IP-10(CXCL10) mRNA. NF-${\kappa}B$ activation is a component of this synergistic effect of IL-18 pretreatment. These results provide useful information, which may facilitate the elucidation of the action mechanisms underlying IL-18 effect on the expression of IP-10(CXCL10) mRNA.

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SIMULATION OF SHIELDING EFFECTS ON THE TOTAL DOSE OBSERVED IN TDE OF KITSAT-1 (KITSAT-1 TDE의 차폐 효과에 의한 총 축적 방사능양 변화에 대한 연구)

  • 김성준;신영훈;민경욱
    • Journal of Astronomy and Space Sciences
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    • v.18 no.1
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    • pp.71-80
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    • 2001
  • The threshold voltage shift observed in TDE (Total Dose Experiment) on board the KITAT-1 is converted into dose (rad($SiO_2$)) using the result of laboratory calibration with Co-60 gamma ray source in KAERI (Korea Atomic Energy Research Institute). Simulation using the NASA radiation model of geomagnetosphere verifies that the dose difference between RADFET1 and RADFET3 observed on KITSAT-1 comes from the difference in shielding thickness at the position of these RADFETs.

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IRRADIATION EMBRITTLEMENT OF CLADDING AND HAZ OF RPV STEEL

  • Lee J.S.;Kim I.S.;Jang C.H.;Kimura A.
    • Nuclear Engineering and Technology
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    • v.38 no.5
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    • pp.405-410
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    • 2006
  • Microstructural features and their related mechanical property changes in the 309L cladding and the heat affected zone (HAZ) of SA508 cl.3 steel were investigated through the use of TEM, tensile and small punch (SP) tests. The specimens were irradiated at 563 K up to the neutron fluences of $5.79{\times}10^{19}n/cm^2$ (>1MeV). The microstructure of the clad was mainly composed of a fcc ${\gamma}-phase$, a low percentage of bcc ${\delta}-ferrite$, and a brittle ${\sigma}-phase$. Along the weld fusion line there formed a heavy carbide precipitation with a width of $20{\sim}40{\mu}m$, showing preferential cracking during plastic deformation. The yield stress and ductile-to-brittle transition temperature (DBTT) of the irradiated clads increased. The origin of the hardening and the shift of the DBTT are discussed in terms of the irradiation-produced defect clusters of a fine size and brittle ${\sigma}-phase$.

Kinetics on Direct Synthesis Dimethyl Ether (디메틸에테르의 직접반응 속도론)

  • Cho Wonihl;Choi Chang Woo;Baek YoungSoon;Row Kyung Ho
    • 한국가스학회:학술대회논문집
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    • 2005.10a
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    • pp.83-87
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    • 2005
  • The kinetics of the direct synthesis of DME was studied under different conditions over a temperature range of $220\~280^{\circ}C$, syngas ratio $1.2\~ 3.0$ All experiment were carried out over hybrid catalyst, composed to a methanol synthesis catalyst (Cu/ZnO/$Al_2O_3$) and a dehydration Catalyst ($\gamma$-Al_2O_3$) The observed reaction rate qualitatively follows a Langmiur-Hinshellwood type of reaction mechanism. Such a mechanism is considered with three reaction, methanol synthesis, methanol dehydration and water gas shift reaction. From a surface reaction with dissociative adsorption of hydrogen, methanol and water, individual reaction rate was determined

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Change of Phase Transformation Temperature at Fabricated Membrane using Sol-gel Method

  • Cheong, Hun;Choi, Duck-Kyun;Cheong, Deock-Soo
    • Journal of the Korean Ceramic Society
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    • v.38 no.10
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    • pp.876-880
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    • 2001
  • The supported and unsupported boehmite ($\gamma$-AlOOH) membranes were prepared using a boehmite sol. The supported membrane was consisted of a porcelain support, two intermediate $\alpha-{Al_2}{O_3}$ layers, and a top boehmite membrane. XRD patterns showed that the supported top membrane had a higher $\theta-$ to $\alpha-{Al_2}{O_3}$ transformation temperature compared to the unsupported membrane. This result was also confirmed from microstructural study of the membrane. The shift in the phase transformation temperature should be explained by difference of a stress generated in the supported top membrane due to interaction between the support layers and the top membrane.

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The Effect of Microstructures on Yield Strength and Impact Properties of a Microalloyed Steel (미세합금강의 조직이 항복강도와 충격치에 미치는 영향)

  • Jo, Jong-Chun;Werner Osterler
    • 한국기계연구소 소보
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    • s.16
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    • pp.29-39
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    • 1986
  • Several heat treatment were applied to on HSLA steel of type StE47 (German standard) to produce five ferrite microstructures of different strength and at least two different grain sizes respectively. Whereas the ferrite microstructure had a strong influence on yield strength the effect of grain size was negligible. The different strength levels could be explained by regarding the arrangement of dislocations and vanadium carbide particles, and their mutual interaction. Specimens tranformed at $600^{\circ}C$ showed the highest strength levels. In this case precipitation has occured after the $\gamma$- $\alpha$ transformation. Very small VC particles are arranged mostly along dislocation lines. Increasing both, grain size and pearlite volume fraction leads to a remarkable shift of transition temperature which was further enhanced by increasing ferrite strength.

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A Technique to Circumvent V-shaped Deconvolution Error for Time-dependent SRAM Margin Analyses

  • Somha, Worawit;Yamauchi, Hiroyuki;Yuyu, Ma
    • IEIE Transactions on Smart Processing and Computing
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    • v.2 no.4
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    • pp.216-225
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    • 2013
  • This paper discusses the issues regarding an abnormal V-shaped error confronting algebraic-based deconvolution process. Deconvolution was applied to an analysis of the effects of the Random Telegraph Noise (RTN) and Random Dopant Fluctuation (RDF) on the overall SRAM margin variations. This paper proposes a technique to suppress the problematic phenomena in the algebraic-based RDF/RTN deconvolution process. The proposed technique can reduce its relative errors by $10^{10}$ to $10^{16}$ fold, which is a sufficient reduction for avoiding the abnormal ringing errors in the RTN deconvolution process. The proposed algebraic-based analyses allowed the following: (1) detection of the truncating point of the TD-MV distributions by the screening test, and (2) predicting the MV-shift-amount by the assisted circuit schemes needed to avoid the out of specs after shipment.

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Performance Analysis of FFH/MFSK System with Clipper Receiver in the Presence of Multitone Interference (다중톤 재밍 환경에서 clipper 수신기를 사용하는 FFH/MFSK 시스템의 성능 분석)

  • 전근표;곽진삼;권오주;박재돈;이재홍
    • Proceedings of the IEEK Conference
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    • 2003.11c
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    • pp.15-19
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    • 2003
  • In this paper, the bit error rate (BER) performance of the fast frequency hopping/M-ary frequency shift keying system using the clipper receiver is analyzed by using the characteristic function (CF) technique in the presence of n=1 band multitone jamming and additive white Gaussian noise environment. The CFs of the clipper receiver outputs are derived as a infinite series representation using Gamma function and Marcum's Q -function. The analytical results are validated with various simulation results. Performance comparisons with linear combining receiver are shown that the BER performance of the clipper receiver is much better than that of the linear combining receiver In addition, as the clipping level approaches to infinity, it is shown that the clipper receiver simply performs a linear combining without clipping and there exists an optimum value of diversity level (the number of hops per symbol) that maximizes the worst case BER performance of the clipper receiver.

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Small Group Velocity of Line Defect in Two-dimensional Photonic Crystal (2차원 광결정 선결함의 낮은 군속도)

  • Lee, Myoung-Rae;Kim, Gyeong-Rae;Shin, Won-Jin;Kim, Chang-Kyo;Hong, Chin-Soo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.23 no.2
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    • pp.128-132
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    • 2010
  • Photonic crystal is dielectric materials or a set of different dielectric materials with periodic structure. Line defect is obtained by leaving out a row of rods along the $\Gamma$-X direction. We showed the change of group velocity in waveguide mode and found resultant small group velocity. Characteristics of the small group velocity were described by electric field distribution. Investigating the phase shift, it is confirmed if small group velocity is positive or negative.