• Title/Summary/Keyword: Gamma dose rate

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Development of a Stereotactic Device for Gamma Knife Irradiation of Small Animals

  • Chung, Hyun-Tai;Chung, Young-Seob;Kim, Dong-Gyu;Paek, Sun-Ha;Cho, Keun-Tae
    • Journal of Korean Neurosurgical Society
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    • v.43 no.1
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    • pp.26-30
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    • 2008
  • Objective : The authors developed a stereotactic device for irradiation of small animals with Leksell Gamma Knife Model C. Development and verification procedures were described in this article. Methods : The device was designed to satisfy three requirements. The mechanical accuracy in positioning was to be managed within 0.5 mm. The strength of the device and structure were to be compromised to provide enough strength to hold a small animal during irradiation and to interfere the gamma ray beam as little as possible. The device was to be used in combination with the Leksell G-$frame^{(R)}$ and $KOPF^{(R)}$ rat adaptor. The irradiation point was determined by separate imaging sequences such as plain X-ray images. Results : The absolute dose rate with the device in a Leksell Gamma Knife was 3.7% less than the value calculated from Leksell Gamma $Plan^{(R)}$. The dose distributions measured with $GAFCHROMIC^{(R)}$ MD-55 film corresponded to those of Leksell Gamma $Plan^{(R)}$ within acceptable range. The device was used in a series of rat experiments with a 4 mm helmet of Leksell Gamma Knife. Conclusion : A stereotactic device for irradiation of small animals with Leksell Gamma Knife Model C has been developed so that it fulfilled above requirements. Absorbed dose and dose distribution at the center of a Gamma Knife helmet are in acceptable ranges. The device provides enough accuracy for stereotactic irradiation with acceptable practicality.

Effects of Low Dose Gamma Radiation on the Growth and Antioxidant Enzyme Activities of Chinese Cabbage (Brassica campestris L.) Seedlings (배추 유식물의 생장과 항산화효소의 활성도에 미치는 저선량 방사선의 효과)

  • 김재성;이영근;백명화;김동희;이영복
    • Korean Journal of Environmental Biology
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    • v.18 no.2
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    • pp.247-253
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    • 2000
  • In order to investigate the stimulatory effect(hormesis) of low dose gamma-radiation on the seeding growth of old seeds with respect to antioxidant defense systems, various doses of gamma radiation to the 5-year-old dried seeds of Chinese cabbage (Brassica campestris L. cv Sulin eockaei). Compared to the new, 1-year- old seeds, old seeds irradiated by low does gamma radiation in the range of 1-2 Gy showed vigor growth as revealed by statistically significant increases both in the germination rates and the leaf size and fresh weight. Further, seedlings grown from seeds treated by low dose gamma radiation showed higher peroxidase and catalase activities than non-treated seedlings. These results suggest that the antioxidant defense systems could be closely related to the stimulatory effects of low dose radiation. [antioxidant enzyme, chinese cabbage, gamma radiation, germination rate, hormesis]

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Application of Commercial PIN Photodiodes to develope Gamma-Ray Dosimeters (감마선 선량계를 개발하기 위한 상용 PIN 포토 다이오드의 응용)

  • Jeong, Dong-Hwa;Kim, Sung-Duck
    • Journal of Sensor Science and Technology
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    • v.9 no.4
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    • pp.274-280
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    • 2000
  • This paper deals with an experimental study to apply commercial semiconductors to measure radiation dose rate for gamma ray. Since the low cost, small size, high efficiency and ruggedness of silicon photodiodes make them attractive photodetectors, they coulde be effectively used in measuring any radiation such as gamma ray. Most PN photodiodes show that the reverse current increases when the light is increased. Therefore the depletion region of them have influence on the reverse current, so we choose silicon PIN photodiodes with large depletion region. In order to detect radiation dose rate and then, to apply in developing any gamma ray dosimeter, some examinations and experiments were performed to PIN photodiodes in this work. Two kinds of PIN photodiodes, such as NEC's PH302 and SIEMENS's BPW34, were tested in a Co-60 gamma irradiation facility with a semiconductor parameter analyzer. As a result, we found that such PIN photodiodes present good linearity in diode current characteristics with dose rate. Therefore silicon PIN photodiodes could be suitably used in designing gamma ray dosimeters.

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Sensitivity of Lavender to Proton, Electron, and Gamma Radiation

  • Chen, Wensheng;Li, Hui;Shi, Lei;Bai, Hong Tong
    • Horticultural Science & Technology
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    • v.34 no.1
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    • pp.122-133
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    • 2016
  • While ion beams are widely used in plant breeding, little is known about the sensitivity of Lavandula angustifolia (lavender) to ionizing radiation. To compare the biological effects of different types of ionizing radiation on the germination and survival rates of lavender, we exposed lavender seeds to gamma rays, 3 MeV electron beams, and 1.89 MeV proton ion beams. We observed that the seed germination rate decreased with increasing dosages of all three types of ionizing radiation. The malformation rate of lavender seedlings exposed to electron beams and gamma rays increased with increasing radiation dosage. By contrast, the effect of the accelerated proton beams on the malformation rate was negatively correlated with the dosage used. The survival rate of lavender seedlings exposed to the three types of ionizing radiation decreased in a dose-dependent manner. In addition, the survival rate of seedlings irradiated with proton and electron beams decreased more slowly than did that of seedlings irradiated with gamma rays. The half-lethal dose of gamma rays, electron beams, and proton beams was determined to be 48.1 Gy, 134.3 Gy, and 277.8 Gy, respectively, and the most suitable proton-ion energy for lavender seeds in terms of penetration depth was determined to be 5 MeV. These findings provide valuable information for the breeding of lavender by radiation mutation.

Stimulation Effect of Early Growth in Crops by Low Dose Radiation (저선량 방사선에 의한 작물 초기생육 촉진효과)

  • Kim, Jae-Sung;Song, Hi-Sup;Kim, Jin-Kyu;Lee, Young-Keun;Lee, Young-Bok
    • Korean Journal of Environmental Agriculture
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    • v.17 no.2
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    • pp.156-159
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    • 1998
  • Germination rate and early growth in crop such as rice,soybean,and perilla were observed after irradiation of $^{\gamma}$-ray (Co-60) in order to determine the effects of low does radiation. The low dose radiation was able to improve the early growth in crops and their agricultural charaters. Germination rate of 2Gy-irradiatied rice seeds was high and also were seeding height and fresh weight of the 0.5 Gy-irradiated. Germination rate and early growth of soybean were high in 4Gy-irradiated group. Perilla gew ot so promisingly after after low dose irradiation,however there slightly increasing effects on germination rate, seeding height and fresh weightat 2Gt-, 1Gy-, and 1Gy irradiated group, respectively.

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Radiation Effects on the Power MOSFET for Space Applications

  • Lho, Young-Hwan;Kim, Ki-Yup
    • ETRI Journal
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    • v.27 no.4
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    • pp.449-452
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    • 2005
  • The electrical characteristics of solid state devices such as the bipolar junction transistor (BJT), metal-oxide semiconductor field-effect transistor (MOSFET), and other active devices are altered by impinging photon radiation and temperature in the space environment. In this paper, the threshold voltage, the breakdown voltage, and the on-resistance for two kinds of MOSFETs (200 V and 100 V of $V_{DSS}$) are tested for ${\gamma}-irradiation$ and compared with the electrical specifications under the pre- and post-irradiation low dose rates of 4.97 and 9.55 rad/s as well as at a maximum total dose of 30 krad. In our experiment, the ${\gamma}-radiation$ facility using a low dose, available at Korea Atomic Energy Research Institute (KAERI), has been applied on two commercially available International Rectifier (IR) products, IRFP250 and IRF540.

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Effect of Low-Dose Gamma Radiation to Enhance Germination Rate in Bottle Gourd and Pumpkin Seeds (참박과 호박 종자의 발아촉진을 위한 저선량 감마선의 효과)

  • Kim, Jae-Sung;Baek, Myung-Hwa;Lee, Young-Keun;Lee, Hae-Youn;Yoo, Jun-Cheol
    • Korean Journal of Environmental Agriculture
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    • v.21 no.3
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    • pp.202-207
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    • 2002
  • To establish the seed treatment method of the gamma radiation for germination enhancement of bottle gourd(Lagenaria siceraria Standl.) and pumpkin(Cucurbita ficifolia Bouche), seeds were irradiated with the dose of 1$\sim$20 Gy of the gamma radiation. The germination rate in irradiated group was higher than that of the control, depending on seed condition. In the case of bottle gourd, the germination rate of 70$\sim$80% germinative seed was increased at 4$\sim$20 Gy irradiated groups. Especially, it was the highest at 4 Gy irradiated group. The germination rate of 80$\sim$90% germinative seed was the highest at 4 Gy irradiated group. The germination rate of 70$\sim$80% and 80$\sim$90% germinative seed at 4 days after sowing was increased 66% and 26% at 4 Gy irradiated group, respectively. In the case of pumpkin, the germination rate of 70$\sim$80% and 80$\sim$90% germinative seed was increased at 2 Gy and 8 Gy irradiated group, respectively. Effect of the low-dose gamma radiation on the early growth was enhanced depending on their germination enhancement. Especially, it was the highest at 2 Gy irradiated group of 70$\sim$80% germinative seed of pumpkin. Catalase activity of bottle gourd was increased at 4 Gy irradiated group. Catalase and peroxidase activity of pumpkin were increased at 2 Gy and 8 Gy irradiated group. These results suggest that the germination, early growth and physiological activity of bottle gourd and pumpkin seeds could be promoted by the low dose gamma radiation.

Long-term Outcomes of Gamma Knife Stereotactic Radiosurgery of Vestibular Schwannomas

  • Kim, Kang-Min;Park, Chul-Kee;Chung, Hyun-Tai;Paek, Sun-Ha;Jung, Hee-Won;Kim, Dong-Gyu
    • Journal of Korean Neurosurgical Society
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    • v.42 no.4
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    • pp.286-292
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    • 2007
  • Objective : Gamma Knife Stereotactic Radiosurgery (GK SRS) has become an important treatment modality for vestibular schwannomas. We evaluated the tumor control rate, patterns of tumor volume change and preservation of hearing following low-dose radiation for vestibular schwannomas in a homogeneous cohort group in which the mean marginal dose was 12 Gy. Methods : A total of 59 patients were enrolled in this study. All enrolled patients were followed-up for at least 5 years and the radiation dose was 11-13 Gy. Regular MRI, audiometry and clinical evaluations were done and tumor volumes were obtained from MRI using the OSIRIS program. Results : The tumor control rate was 97%. We were able to classify the patterns of change in tumor volume into three categories. Transient increases in tumor volume were detected in 29% of the patients and the maximum transient increase in tumor volume was identified at 6 to 30 months after GK SRS. The transient increases in tumor volume ranged from 121% to 188%. Hearing was preserved in 4 of the 12 patients who had serviceable hearing prior to treatment. There were no other complications associated with GK SRS. Conclusion : Low-dose GK SRS was an effective and safe mode of treatment for vestibular schwannomas in comparison to the previously used high-dose GK SRS. Transient increases in tumor volume can be identified during the follow-up period after low-dose GK SRS for vestibular schwannomas. Physicians should be aware that these increases are not always indicative of treatment failure and that close observation is required following treatments. Unfortunately, a satisfactory hearing preservation rate was not achieved by reducing the radiation dose. It is thought that hearing preservation is a more sophisticated problem and further research is required.

Improvement of Mutation Rate and Reduction of Somatic Effects by Double Treatment of Chemical Mutagens in Barley (화학 돌연변이제 이중처리에 의한 돌연변이율 향상 및 생장저해 경감)

  • 구본철
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.41 no.3
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    • pp.348-353
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    • 1996
  • Mutation tachniques inducing more useful mutations and reducing somatic effects need to be improved for crop breeding. Seeds of barley varieties ; Dema, Grosso were treated with two types of mutagens ; 1) chemical treatment: single treatment or double treatment of two mutagens (N-nitroso-N-methylurea ; MNH, Sodium Azide; NaN$_3$) 2) gamma ray irradiation treatment. After treatment, half of seeds were used for germination test and half of seeds were sown to the field. With the higher dose of mutagen both chemical and gamma ray were plants treated, the higher rate of growth reduction rate was in M$_1$ seedling. In chemical treatment, germination rate of seeds, growth rate of coleoptile and root in double treatment of chemical mutagens were better than single treatments, especially in same dose. Growth inhibition rate of plant in double treatment of 1.0mM MNH(0.5mM MNH + 0.5mM MNH), for example, were less than one of plants of single treatment of 1.0mM MNH in pot and petri dish test. Growth reduction rate of culm and fertility rate in M$_1$ plants double treated in same dose of single treatment were also less than single one. With the higher dose of mutagen both chemical and gamma ray were plants treated, the higher frequency of chlorophyll mutants was in M$_2$ seedling. The rate of chlorophyll mutants in double treatment of chemical mutagens were higher than single treatment. Double treatment methods can be a improved method for induction of new good mutants, which were induced more useful mutations and reduced harmful somatic effects.

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Effects of Low Dose ${\gamma}$ Radiation on the Radiosensitivity of Soybean(Glycine max L.) Plant (저선량 ${\gamma}$선 조사가 대두 식물체의 방사선 감수성에 미치는 영향)

  • Kim, Jae-Sung;Chae, Sung-Ki;Back, Myung-Hwa;Kim, Dong-Hee
    • Korean Journal of Environmental Agriculture
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    • v.19 no.4
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    • pp.324-327
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    • 2000
  • Soybean (Glycine max L. cv. Hwangkeum) seeds were irradiated with the dose of $0{\sim}20$ Gy to investigate the effect of the low dose ${\gamma}-ray$ radiation on the early growth and resistance to subsequent high dose of radiation. Germination rate was not enhanced in the seeds irradiated with low dos ${\gamma}-ray$ but plant height and fresh weight increased in the low dose irradiation group. The optimal radiation dose for the growth increasing was 8 Gy in soybean plant. Growth inhibition of soybean plants by high dose radiation was noticeably reduced by pre-irradiation of low dose radiation, Resistance to subsequent high dose of radiation was effective in 8 Gy and 20 Gy irradiation group.

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