• Title/Summary/Keyword: Gallstone composition

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A Descriptive Study of Gall Stone Patient's Dietary Habits and Nutritional Status (담석증 환자의 식생활양식 및 영양 실태 조사)

  • Kim, Eun-Jung;Lee, Young-Mee
    • Korean Journal of Community Nutrition
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    • v.12 no.6
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    • pp.826-837
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    • 2007
  • Gallstone composition has changed over the past decades in the Korean with a prominent increase in the prevalence of cholesterol gallstone. This trend is possibly due to the westernization of dietary habits. The purpose of this study was descriptive of GB patient's health related eating behaviors and nutrient consumption patterns. One hundred and six gallstone patients who have had cholecystitis surgery enrolled in this study. Anthropomertic indices, such as height, weight, waist circumference, and hip circumference were measured and calculated BMI and WHR. As the biomarker, TC, TG, LDL-C, HDL-C, FBG level and SBP/DBP were measured and analyzed the relationship with GB stone formation. The structured checklist of health related eating behavior and the semiquantitative food frequency questionnaire after pre-test was used in the face to face interview study. The mean age was $54.9{\pm}13.3$ and gallstone disease was more frequent in the fifties and sixties. Mean BMI was $24.3{\pm}2.8$ in males, and $23.4{\pm}3.9$ in females, the average of waist circumference was $91.1{\pm}7.0cm$ in males and females were $85.4{\pm}9.6cm$. The WHR of men and women was $0.93{\pm}0.0,\;0.90{\pm}0.1$, respectively. The obesity and overweight trend was observed in gallstone patients. The mean blood sugar was researched at $114.5{\pm}35.0mg/dL$. And the ratio of both symptoms DM and gallstone was 26.4%. The rate of dramatic eating repast was significantly higher in the females (p<0.01). Males tended to more frequently consume meat, of high fat content meats and greasy food consumption when eating out. The CPF ratio was 57:16.5:26.5. There was a significant positive correlation between WC and energy (r=0.252, p<0.05), carbohydrate (r=0.255, p<0.05) and niacin (r=0.227, p<0.05). In addition, carbohydrate were significantly correlatied with TC (r=0.230, p<0.05). BMI appeared positive in correlation of protein (r=0.201, p<0.05) and fat (r=0.205, p<0.05). These findings provide a little association that dietary habits are related with cholesterol gallstone formation.

Determination of Chemical Composition of Gallbladder Stones and their Association with Induction of Cholangiocarcinoma

  • Hussain, Saad Muhmood;Al-Jashamy, Karim Alwan
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6257-6260
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    • 2013
  • Gallstone disease is a major surgical problem in many populations; it is probably related to diet, especially excessive consumption of meat. The objective of this study was to determine the chemical composition of gallstones and their association with neoplastic changes including cholangiocarcinomas in cholecystectomised patients. The chemical composition of gallstones from 40 patients (8 males and 32 females) was analyzed. This is a prospective study performed in Baquba teaching hospital in the period from 1/10/2012 to 1/1/2013 in which we collected the gallstones for the patients who underwent cholecystectomy, whether open or laparoscopic. The stones were classified according to their chemical composition as a mixed stones (MS), and examined using a stone analysis set (chemical qualitative method) for calcium, magnesium, phosphate, uric acid and oxalate which was used reagent for qualitative determination of main individual components of stones. The results of this study showed the highest incidence of gallstones in the age group 40-49 was 13 cases followed by 11, 8 and 4 cases for age groups 30-39, 50-59, 20-29 and 60 and above, respectively. The chemical analysis showed the majority of gallstones were mixed, 38 containing calcium followed by 37 cases with uric acid, 28 with magnesium, and 25 and 22 stones with oxalate and phosphate, respectively. Microscopically, we confirmed neoplastic changes (17.5%) as cholangiocarcinomas (CCCs) (7.55%) and dysplastic cells of carcinoma in situ in 4 (10%), 31 (77.5%) cases were chronic cholecystitis and 2 (5%) cases were acute cholecystitis with empyema out of bile duct disorders patients. In conclusion, majority of cases had mixed gallstones that involved five and four of inorganic chemicals of calcium, magnesium and phosphate, the highest incidence of gallstones in age group 40-49 years old was 13 cases, and neoplastic changes were confirmed (17.5%) including CCCs, (7.5%) and dysplastic cells of carcinoma in situ (10%), while 31 (77.5%) cases were chronic cholecystitis.

A Study on the Sasang Constitutional Characteristics of Obese Middle-Aged Women (중년비만여성의 사상체질별 특성에 관한 연구)

  • Lim, Jinny;Lee, In-Soon;Koh, Byung-Hee;Song, Il-Byung;Lee, Soo-Kyung
    • Journal of Sasang Constitutional Medicine
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    • v.16 no.3
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    • pp.59-69
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    • 2004
  • 1. Objectives This research is to ascertain relations between the Sasang Constitution and characteristics of the eating attitudes, mental state, body composition, various examination results of obese middle-aged women. 2. Methods The subjects were 31 female patients whose BMI(Body Mass Index) was over $25kg/m^2$ and age was 35~55. It was analysed statistically the results of EAT(The Eating Attitudes Test), DEBQ(Dutch Eating Behavior Questionnaire), BDI(Beck Depression Inventory), STAI(State-Trait Anxiety Inventory), body composition analyser, biochemistry, abdominal ultrasonography, mammography which was surveyed from them. 3. Results and Conclusions 1)There was no relation between the Sasang Constitution and the eating attitudes, eating behaviors. But Taeumin got statistically lower score than Non-Taeumin in 23rd question for emotional eating and 33rd question for environmental eating of DEBQ 2)On the mental state, Taeumin got statistically lower score than Non-Taeumin in BDI, STAI-S 3)On the body composition, Taeumin got statistically higher value than Non-Taeumin in BMI. Soyangin got statistically lower value than Non-Soyangin in BMI, left upper limb water, soft lean mass, body water, trunk water. 4)On the various examinations, Taeumin got statistically lower value than Non-Taeumin in serum albumin. Soyangin got statistically lower value in BMI and higher frequency in gallstone, breast nodule than Non-Soyangin. 5)It was thought that Taeumin's obesity is managed by controling physical factor such as excessive 'Gathering Qi(吸聚之氣)' rather than eating attitudes and psychological factor.

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Simultaneous Determination of Biliary Free and Phospholipid Fatty Acids Using Gas Chromatography-Mass Spectrometry (GC-MS를 이용한 담즙내 유리 지방산 및 인지질 지방산들의 동시 분석)

  • Yang, Yoon Jung;Lee, Seon Hwa;Chung, Bong Chul
    • Analytical Science and Technology
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    • v.13 no.5
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    • pp.592-600
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    • 2000
  • The concentration of free fatty acids and fatty acid composition as well as cholesterol supersaturation in bile may be an important factor in the gallstone formation. Therefore, we simultaneously determinded 23 fatty acids in bile by selected ion monitoring (SIM) method of gas chromatography-mass spectrometry (GC-MS). Biliary fatty acids were extracted by aminopropyl column and the extracts with (phospholipid fraction) or without (free fatty acid fraction) alkaline hydrolysis of phospholipid were derivatized with MSTFA/TMCS (N-methyl-N-trimethylsilyl-trifluoroacetamide/trimethylsilylchloride) mixture in order to be detected on the GC-MS. The recovery range of this method was 61.1-99.0% and the RSD value of within-a-day and day-to-day test were 3.1-25.6% and 3.8-27.0%, respectively. Using this method, biliary profile was investigated in the bile of normal controls and patients with gallstones. The amounts and their distribution of free and phospholipid fatty acids showed different pattern between normal subjects and patients.

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