• 한국식품위생안전성학회지
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• 제6권2호
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• pp.73-78
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• 1991

한국 고유의 구황식품인 구약 고구마의 성분을 분석하고 식이성 섬유질로서 혈청지질 대사에 미치는 영향을 실험한 결과 다음과 같다. 1. 구약고구마는 팽윤성이나 점성이 높은 수용성 섬유성분이 다량 함유되어있다. 2. 체중 증가율에서 구약고구마 투여군은 대조군에 비해 유의성이 없었으나 cholesterol 투여군에서는 6.8%, 고 지방 투여군에서는 9.1% 증가되었다. 4. 간의 cholesterol 값은 구약고구마 투여군이 대조군에 배히 5.9% 낮았으며 cholesterol 투여군보다 30.5%가 낮았다. 5. 혈장 cholesterol 값은 대조군에 비해 13.4% 감소되었으나 고 지방 투여군은 10.7% 증가되었다. 6. 혈청 중 총 지질 함량에 있어서 GM 투여군은 대조군에 비해 7.5% 감소되고 반대로 고 지방 투여군은 11.3%가 증가되었다. 7 혈청효소의 활성 변화에서 구약고구마 투여군은 대조군에 비해 7.5% 감소되고 반대로 고 지방 투여군은 11.3%가 증가되었다. 7. 혈청효소의 활성 변화에서 구약고구마 투여군은 대조군에 비해 GOT가 9.0% 감소되었으나, cholesterol 투여군은 별다른 차이를 나타내지 않았다. GPT는 대조군에 비해 2.1% 감소, 고지방 투여군 보다는 18.5% 감소되었다.

• 대한한의학회지
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• 제26권1호
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• pp.148-160
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• 2005

Objective: We investigated the effects of deer antler extract (DAE) on the expression of the weight, leptin, and serum levels (lipid metabolism) of the obese SD rats induced by a $2\%$ cholesterol diet in vivo. Methods: In vivo, the weight, leptin and serum levels were measured after a period of 7 weeks for obese SD rats induced by a $2\%$ cholesterol diet and treated with DAE of three concentrations (0.938 g/kg/5ml, 1.875 g/kg/5ml, 3.75 g/kg/5ml). Results: 1. Body weight didn't change significantly. 2. Leptin levels significantly decreased (p<0.05). 3. Total cholesterol, triglyceride, LDH, sGOT & sGPT levels significantly decreased in the sample (p<0.05). 4. The HDL cholesterol levels significantly increased in the sample (p<0.05). 5. The average size of the epididymal fat cells significantly decreased as the concentration of deer antler extract increased (p<0.05). Conclusion: Deer antler effects inhibition of obese rats.

• Journal of Nutrition and Health
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• 제33권5호
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• pp.502-506
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• 2000

Effects of powdered siho(bupleuri radix) on serum and liver lipid composition and antioxidative capacity were investigated in rat fed high oxidized fat. Sixty male Sprague-Dawley rats weighing 161.25$\pm$2.51g were blocked into four groups according to body weight and raised seven weeks with basal diet(normal group), basal diet and 10% oxidized fat(control group), basal diet, 10% oxidized fat and 2% powdered siho(2% powdered siho group) and basal diet, 10% oxidized fat and 3% powdered siho(3% powdered siho group). Feed intake, body weight gain and feed efficiency were not significantly different among oxidized fat diet groups. The values of total cholesterol and triglyceride in plasma and liver showed no significantly different(p>0.05) in the oxidized fat diet groups. Plasma HDL-cholesterol showed atendency to increase in powdered siho diet groups. The values of thiobarbituric acid in plasma and liver were lower in the powdered siho diet groups than control group. Plasma GOT and GPT activity showed a tendence to decrease in powdered siho groups. Liver glutathione peroxidase activity showed a tendence to increase in powdered siho diet groups. Thus, it seems that powdered siho had some antioxidative elements.

• 한국산업융합학회 논문집
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• 제27권2_2호
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• pp.445-456
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• 2024

This study aims to suggest service improvement opportunities by analyzing user review data of the top three OTT service apps(Netflix, Coupang Play, and TVING) on Google Play Store. To achieve this objective, we proposed a framework for uncovering service opportunities through the analysis of negative user reviews from OTT service providers. The framework involves automating the labeling of identified topics and generating service improvement opportunities using topic modeling and prompt engineering, leveraging GPT-4, a generative AI model. Consequently, we pinpointed five dissatisfaction topics for Netflix and TVING, and nine for Coupang Play. Common issues include "video playback errors", "app installation and update errors", "subscription and payment" problems, and concerns regarding "content quality". The commonly identified service enhancement opportunities include "enhancing and diversifying content quality". "optimizing video quality and data usage", "ensuring compatibility with external devices", and "streamlining payment and cancellation processes". In contrast to prior research, this study introduces a novel research framework leveraging generative AI to label topics and propose improvement strategies based on the derived topics. This is noteworthy as it identifies actionable service opportunities aimed at enhancing service competitiveness and satisfaction, instead of merely outlining topics.

• Korean Journal of Acupuncture
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• 제25권2호
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• pp.143-158
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• 2008

Objectives : The purpose of this study is to observe the anti-oxidative effects of electroacupuncture at GB34(Yangreungcheon) in rats. Methods : The authors performed several experimental items including measurements of body weight, relative liver weight, levels of albumin, total bilirubin, LDL-cholesterol, LDH, GOT and GPT in blood serum, levels of SOD, glutathione, catalase, NO and MDA in liver, and histological analysis of liver. The conclusions are as follows. Results : 1. In the GB34-EA group, liver index was lower than those of the control group and the holder group. 2. In the GB34-EA group, the levels of albumin and total bilirubin in serum were increased significantly compared to those of the control and the holder group. LDL-cholesterol level was decreased significantly compared to those of the control group and the holder group. 3. In the GB34-EA group, liver SOD, glutathione, catalase activity were increased, and NO concentration in liver was decreased significantly compared to those of control and the holder group. 4. In the GB34-EA group, the density of liver tissue was more similarly maintained to that of the normal group compared to those of the control group, holder group and sham-EA group. Conclusions : These results suggest that electroacupuncture at GB34 may have an antioxidant effect in rat.

• 대한한의학회지
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• 제37권1호
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• pp.34-40
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• 2016

Objectives: To observe safety and efficacy of herbal medicine for psoriasis patients. Methods: We did retrospective chart review for 107 psoriasis patients who had been treated by herbal medicine for 2 months, and we analyzed the liver function test (LFT) results and Psoriasis Area and Severity Index (PASI) scores of before and after the treatment. Results: The mean LFT and the number of patients with abnormal LFT decreased after the treatments. More than 95% of patients with normal LFT maintained normal results at after the treatment, and only 2.1% and 4.6% patients with normal LFT showed abnormal Glutamic Oxaloacetic Transaminase (GOT) and Glutamic Pyruvic Transaminase (GPT) results at after the treatment. Also, both mean PASI scores for all patients and patients with abnormal LFT before the treatment decreased significantly. Conclusions: This study suggest that herbal medicine may be safe and effective treatment for psoriasis.

• 한국안전학회지
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• 제19권4호
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• pp.48-54
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• 2004

The recent Ire incident in an elementary school of Chonan city causes the media focus on the fire safety of residential container buildings. In this study, real fire tests were conducted in this kind of buildings. Combustion products including $O_2,\; CO_2,\;CO,\;NOx,\;SOx,\;HCI,\;HCN$ were measured, and blood samples of lab rats were analyzed in terms of Co-Hb, Glucose, AST(GOT), ALT(GPT), in order to investigate the hazard-reduction effects of employing gas mask protected with filter during the fire emergency of residential container buildings. According to the test results, whether or not employing the filter showed a sheer difference in the toxicity of the fire-induced gases, and then the importance of wearing a gas mask was evidently demonstrated.

• Journal of Nutrition and Health
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• 제34권7호
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• pp.741-747
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• 2001

The effects of fruiting body of Cordyceps militaris on the growth, the food intake, the food efficiency ratio, the lipid metabolism, the serum protein level ad enzyme activity in male rats were studied. Sprague-Dawley rats were fed four types of diets for five weeks, respectiely: a control diet, a control diet supplemented with 2%, 3% or 4% fruiting body of Cordyceps militaris(CF) powder. In rats fed 2% or 3% CF diets the body weight gain, the food intake, the concentratons of hepatic triglyceride and serum LDL-cholesterol, the atherogenic index, and the total lipid, total cholesterol, triglyceride and phospholipid in serum were similar to those in rats fed the control diet. Whereas, in 4% CF diet these were significantly decrased. But the all CF diets feeding could not decrease the food efficiency ratio, the weights of liver, pancreas, spleen, kidney and heart, and the concentration of serum HDL-cholesterol. Also, it was shown that the concentrations of glucose, total protein, albumin, urea and creatinine, and the GOT, GPT, LDH, ${\gamma}$-GTP and ALP activities were the same levels in serum of rats of fed all the experimental diets.

• 한방재활의학과학회지
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• 제19권3호
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• pp.91-100
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• 2009

Objectives : The purpose of this study was to find the characteristics of Sasang Constitution, Soeumin, Soyangin and Taeumin, Using Regular Medical Inspection. Methods : Subjects of our study were 325 cases who took regular medical inspection. We collected the data of body composition analysis, 7-zone-diagnostic system, blood analysis, and analyzed by Sasang Constitution, Soeumin, Soyangin and Taeumin. Results and Conclusions : 1. In body composition analysis, Taeumin was significantly higher than Soeumin and Soyangin about soft lean mass, body fat mass, waist-hip ratio, body water index, body mass index and basal metabolic rate. In blood analysis, Taeumin was significantly highest about total protein, albumin, GPT, hemoglobin, WBC, triglyceride. In 7-zone-diagnostic system, Taeumin had the highest level at Zone 1, 2. 2. Taeumin had more significant differences than other Sasang constitutions about the parameters of regular medical inspection. 3. Body composition analysis had the most parameters that showed differences among the constitutions, followed by blood analysis and 7-zone-diagnostic system.

• 대한한의학회지
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• 제15권2호
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• pp.156-172
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• 1994

This study was performed to evaluate the effect of the Gamichunggantang on recovering from liver injury induced by d-galactosamine and ${\alpha}$-naphthylisothiocyanate. and following results were obtained. 1. The increases of the serum GOT. GPT activities in mice induced by d-galactosamine and ${\alpha}$-naphthylisothiocyanate were inhibited significantly by the administration of the Gamichunggantang. 2. The increases of the total cholesterol. triglyceride and blood urea nitrogen levels in mice induced by d-galactosamine and ${\alpha}$-naphthylisothiocyanate were significantly inhibited by the administration of the Gamichunggantang. 3. The increase of the ALP activity in mice following liver injury induced by d-galactosamine and ${\alpha}$-naphthylisothiocyanate were inhibited to an extend. but it was not significant. 4. It is considered that the efficacy of the Gamichunggantang on liver cell injury depends on its concentration rate.