• Title/Summary/Keyword: GP5+/6+

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Anticarcinogenic Effect of Ginseng Extracts Depending on the Types and Ages Using Yun's Anticarcinogenicity Test(II) (벤조피렌으로 유도된 마우스 폐선종에 대한 인삼분말의 연근별 항발암효과(II))

  • Yun, Taik-Koo;Lee, Yun-Sil
    • Journal of Ginseng Research
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    • v.18 no.3
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    • pp.160-164
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    • 1994
  • In this study, we investigeated the anticarcinogenicity of various types and ages of ginseng extracts as an extended study using Yun's anticarcinogenicity test. Fresh ginseng at 1.5, 3, 4, 5 and 6 years was dried and powdered. And white ginseng was processed in the same way that of fresh ginseng after removal fo the ginseng cortex and fine root. For red ginsneg, fresh ginseng was steamed and dried. Each ginseng powder was extracted and extracts was freeze dried. Newborn N:GP(S) mice were given a single subcutaneous injection of 0.5 mg of benzo(a)pyrene(BP). Various types and ages of ginseng extracts at 2.5mg/ml were orally administered. All the mice were sacrificed at the 9th week. The following results were obtained. In the dried fresh ginseng extract treated group, the incidence of lung adenoma induced by BP was 63.9% and its incidence was reduced to 48.3%, 52.5%, 51.8%, 47.5% and 44.1% after co-treatment with 1.5, 3, 4, 5 and 6 year-dried fresh ginseng, respectively. The incidence of lung adenoma induced by BP on the white ginseng extract treated group was 41.3% and decreased to 31.0%, 46.0%, 44.0% and 26.5% after co-treatment with 3, 4, 5 and 6 year-white ginseng, respectively. In the red ginseng extract treated group, the incidence of lung adenoma induced by BP was 47.5% and its incidence diminished to 40.7%, 35.0%, 30.1%, 30.0% and 26.3% after co-treatment with 1.5, 3, 4, 5 and 6 year-red ginseng, respectively. From the above results, we concluded that a statistically significant anticarcinogenic effect was observed in extracts of 6 year-dried fresh ginseng, 6 year-white ginseng, and 4, 5 and 6 year-red ginseng and it is suggested that the anticarcinogenicity of ginseng varies according to the types and ages Key words Ginseng extract, types and ages. anticarcinogenic, newborn mice, lung tumor.

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Modelling the performance of self-compacting SIFCON of cement slurries using genetic programming technique

  • Cevik, Abdulkadir;Sonebi, Mohammed
    • Computers and Concrete
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    • v.5 no.5
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    • pp.475-490
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    • 2008
  • The paper explores the potential of applicability of Genetic programming approach (GP), adopted in this investigation, to model the combined effects of five independent variables to predict the mini-slump, the plate cohesion meter, the induced bleeding test, the J-fiber penetration value, and the compressive strength at 7 and 28 days of self-compacting slurry infiltrated fiber concrete (SIFCON). The variables investigated were the proportions of limestone powder (LSP) and sand, the dosage rates of superplasticiser (SP) and viscosity modifying agent (VMA), and water-to-binder ratio (W/B). Twenty eight mixtures were made with 10-50% LSP as replacement of cement, 0.02-0.06% VMA by mass of cement, 0.6-1.2% SP and 50-150% sand (% mass of binder) and 0.42-0.48 W/B. The proposed genetic models of the self-compacting SIFCON offer useful modelling approach regarding the mix optimisation in predicting the fluidity, the cohesion, the bleeding, the penetration, and the compressive strength.

Evaluation of Human Papillomavirus Infections in Prostatic Disease: a Cross-Sectional Study in Iran

  • Ghasemian, Ehsan;Monavari, Seyed Hamid Reza;Irajian, Gholam Reza;Nodoshan, Mohammad Reza Jalali;Roudsari, Rouhollah Vahabpour;Yahyapour, Yousef
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.3305-3308
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    • 2013
  • Background: The role of inflammation in prostate diseases is suggested by the presence of inflammatory cells within the prostate in benign prostatic hyperplasia (BPH) and prostate cancer (PCa) patients. In addition, bacterial and viral infection may lead to chronic and recurrent inflammation of the prostate. The human papillomaviruses (HPVs) are a family of sexually transmitted viruses which have been implicated in the aetiology of cervical cancer and several other malignancies. This study evaluated the frequency of HPV infection in individuals with prostatic disease in Iran. Materials and Methods: The study included formalin fixed paraffin- embedded tissue samples of 196 primary prostate cases, including 29 PCa and 167 BPH samples. HPV DNA was purified and amplified through MY09/MY11 and GP5+/GP6+ primers with nested PCR. All patients were interviewed using a questionnaire to collect demographic information. Results: Nested PCR showed that HPV DNA was found in 17.2 percent of PCa samples and 4.8 percent of BPH samples (not significant). Conclusions: Our data do not support a significant role of HPV infection in prostatic disease in Iranian patients, but demographic data indicated a probable association between presence of HPV DNA and risk of inflammation in prostate tissue which might lead to prostate carcinoma. Further studies are required to elucidate any roles of HPV infection in prostatic disease.

A Study on Effective Planning Method of the Check-off Fund Program for Egg (계란자조금의 효과적인 조성방안에 관한 연구)

  • Kim, Dong Jin;Hong, Sung Kyu;Kim, Yoon doo
    • Korean Journal of Poultry Science
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    • v.44 no.1
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    • pp.51-57
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    • 2017
  • Subsequent to the introduction of the "Laws on Consumption Promotion of Livestock Products" in 2002, a mandatory check-off system for the egg industry was introduced in June 2009. Unlike other livestock products, the check-off on eggs is financed not from the sale of the egg-the end product-but from the spent hen. Variables such as the falling price of spent hens lead to a low financing rate; The present farm allotment rate of 14%, introduced in 2015, is much higher than the 0.2% to 0.3% check-off rate in other types of business, thus placing a huge burden on farms. When check-off is financed from the egg, it is expected that 6.5 billion won will be raised using a rate of 0.3% of sale proceeds, Therefore, it is urgent for the government to establish infrastructure to enable producers and merchants to do business through Grade & Packing centers. This can be achieved by the staged construction of local Grade & Packing centers. Check-off should continue to be financed from the present spent hen until this infrastructure is established, and an institutional strategy should be provided by the government to raise the financing rate accurately and transparently using statistical treatment of supply data for spent hens as a short-term alternative.

COMPARATIVE STUDY ON FLUORIDE RELEASE AND RE-UPTAKE CAPACITY OF SEVERAL FLUORIDE-RELEASING RESTORATIVE MATERIALS (수종의 수복재의 불소 적용법에 따른 불소 유리에 관한 비교 연구)

  • Lee, Yeon-Ho;Yoo, Seung-Hoon;Kim, Jong-Soo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.33 no.1
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    • pp.25-34
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    • 2006
  • Fluoride released from dental restorative materials effectively declines the incidence and activity of dental caries and inhibits tooth demineralization. This study investigated the fluoride release and uptake characteristics of one composite resin $(Z-250^{TM})$ three glass ionomer-based restorative material ($Dyract^{(R)}$ AP, Fuji II $LC^{(R)}$, Fuji IX GP $Fast^{(R)}$) Forty discs(6mm diameter and 1mm height) were prepared for each material. Each disc was immersed in 5ml of distilled water within polyethylene vial and stored at $37^{\circ}C$. The distilled water was changed every 24 hours and the release of fluoride was measured for 31 days. At the end of this period, each specimen was subjected to one of four treatments : (A) no fluoride treatment (control), (B) application of a fluoride dentifrice (500ppm) for three minutes three times; (C) application of the 1.23% acidulated phosphate fluoride(APF) foam for one minute once, (D) the same regimen as (B), plus application of the APF foam for one minute once. Then, all samples were reassessed for an additional 7 days. For all samples, the greatest fluoride release was observed after the first day of the study but diminished with time. On the 7th day of the study, fluoride release level was stabilized. Fuji II $LC^{(R)}$ and Fuji IX GP $Fast^{(R)}$ released higher amount of fluoride than other materials ; however, no statistically significant difference was found from Fuji II $LC^{(R)}$ and Fuji IX GP $Fast^{(R)}$. The amount of fluoride of $Dyract^{(R)}$ AP, Fuji II $LC^{(R)}$ and Fuji IX GP $Fast^{(R)}$ was increased after fluoride treatment, and diminished with time.

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Effect of Temperature and Various Pre-treatments on Germination of Hippophae rhamnoides Seeds (갈매보리수나무 종자의 온도 및 여러 가지 전처리에 따른 발아반응)

  • Choi, Chung-Ho
    • Korean Journal of Plant Resources
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    • v.25 no.1
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    • pp.132-141
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    • 2012
  • This study was carried out to test seed germination responses to temperatures and pre-treatments in Hippophae rhamnoides, which has many abilities in antioxidant activity, soil improvement and erosion control. H. rhamnoides seeds were placed at 10, 15, 20, 25, 30 and $35^{\circ}C$ under light condition. As the results, germination percentage (GP) was the highest at 15 and $20^{\circ}C$, and mean germination time (MGT), germination rate (GR) and germination value (GV) were the highest at $25^{\circ}C$. Quadratic and linear regression model were used to determine the cardinal temperatures such as base ($T_b$), maximum ($T_m$) and optimum ($T_o$) temperature for germination. In quadratic regression model using PG, $T_b$, $T_m$ and $T_o$ was estimated as 0.6, 36.4 and $18.5^{\circ}C$, respectively, and temperature range for germination was $35.8^{\circ}C$. In linear regression model using GR, $T_b$, $T_m$ and $T_o$ was estimated as 8.3, 35.4 and $25.3^{\circ}C$, respectively, and temperature range for germination was $27.2^{\circ}C$. Germination properties were investigated after H. rhamnoides seeds were treated by prechilling (1, 2, 4, 6 and 8 weeks), stratification (2, 4, 6 and 8 weeks), solid matrix priming (seed : carrier : water = 5 : 1 : 7, 8, 9 and 10), osmo-priming (-0.25, -0.5, -1.0 and -1.5 MPa) and calcium chloride ($CaCl_2$) -priming (100, 200, 300 and 400 mM). The highest GP was observed in $CaCl_2$ 300 and 400 mM treatments, and MGT was the shortest in stratification 6 and 8 weeks treatments. GR and GV were the highest and GP was the second highest when seeds were prechilled for 1 and 2 weeks. Consequently, prechilling 1 or 2 weeks treatment was considered as the appropriate method when we contemplate qualitative and quantitative effects in seedling production.

Analysis of integrated GPS and GLONASS double difference relative positioning accuracy in the simulation environment with lots of signal blockage (신호차폐 시뮬레이션 환경에서의 통합 GPS/GLONASS 이중차분 상대측위 정확도 분석)

  • Lee, Ho-Seok;Park, Kwan-Dong;Kim, Du-Sik;Sohn, Dong-Hyo
    • Journal of Navigation and Port Research
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    • v.36 no.6
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    • pp.429-435
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    • 2012
  • Although GNSS hardware and software technologies have been steadily advanced, it is still difficult to obtain reliable positioning results in the area with lots of signal blockage. In this study, algorithms for integrated GPS and GLONASS double difference relative positioning were developed and its performance was validated via simulations of signal blockages. We assumed that signal blockages are caused by high-rise buildings to the east, west, and south directions. And then, GPS-only and integrated GPS/GLONASS positioning accuracy was analysed in terms of 2-dimensional positioning accuracies. Compared with GPS-only positioning, the positioning accuracy of integrated GPS/GLONASS improved by 0.3-13.5 meters.

Prevalence of Human Papillomavirus Types and Phylogenetic Analysis of HPV-16 L1 Variants from Southern India

  • Kabekkodu, Shama Prasada;Bhat, Samatha;Pandey, Deeksha;Varghese, Vinay Koshy;Shukla, Vaibhav;Ghosh, Supriti;Kushtagi, Pralhad;Bhat, Parvati;Gopinath, Puthiya Mundayat;Satyamoorthy, Kapaettu
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.5
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    • pp.2073-2080
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    • 2015
  • Background: The human papillomavirus (HPV) and its variants show wide geographical distribution and have been reported to cause cervical lesions. With cervical neoplasia as the leading cancer in Indian women, the aim of the present study was to evaluate the multiple infection HPV type distribution and variant genotypes in cervical samples from the coastal Karnataka region, India. Materials and Methods: A total of 212 samples were screened by nested polymerase chain reaction using PGMY9/11 and GP5+/6+ primers. HPV positive samples were sequenced to identify the types and a phylogenetic tree was constructed using the neighbor-joining method. Results: Sequence analysis identified a total of 14 HPV types distributed in 20%, 73.3% and 82.5% of non-malignant, pre-malignant [low grade squamous intraepithelial lesion (LSIL) and high grade squamous intraepithelial lesion (HSIL)] and cervical cancer samples. The distribution of high risk HPV in cancer samples was HPV 16, 76.4%, HPV18, 11.7%, HPV81, 2.9%, HPV31, 1.4%, HPV35, 1.4% and HPV 45, 1.4%. Multiple infections were observed in 11.8% of tumor samples with HPV 16 contributing to 62.5% of cases. In non-malignant samples, 20% of HPV positive samples were detected with HPV16, 82.3%, HPV33, 5.8% and HPV58, 5.8% and very low incidence of multiple infections. Comparative phylogenetic analysis of HPV variants identified 9 HPV sequences as new papillomavirus species, predominantly classified as European lineage type. Conclusions: The findings for HPV infections associated with progression of cervical cancer in coastal Karnataka region and HPV variant analysis provide baseline data for prevention and HPV vaccination programs.

Development of Auto-Parking Algorithm for Driving in Urban (무인차량의 자동주차 알고리즘 개발)

  • Cho, Kyoung-Hwan;Chung, Jin-Wok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.5
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    • pp.2360-2366
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    • 2011
  • The Unmanned Ground Vehicle is comprised of four systems of obstacle detection: The navigation system, vehicle controlling system, obstacle detecting and an integration system that use the various sensors. The research introduced utilizes 6 lasers to recognize obstacles. The system operates an avoidance system within the unmanned ground vehicle, using six lasers. The Unmanned Ground Vehicle's parallel parking and right angle parking is in development using algorithms. This algorithms' certification is intended to be installed in the encoder, in the GPS. By using the Laser Scannerfor the position's calculation, errors are both reduced and minimized, so the tire's slip minimized to the point where the vehicle had a limit of about 5Km/h.

Analysis of Relationship between GPs and SPs in CMMI Maturity Level 2 and Verifying the Applicable Efficiency (CMMI 성숙도 2단계 GP와 SP간 상호 연관성 분석 및 적용 효율성 검증)

  • Lee, Min-Jae;Rhew, Sung-Yul;Kim, Sung-Tae
    • Journal of KIISE:Software and Applications
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    • v.37 no.6
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    • pp.480-485
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    • 2010
  • In the characteristics of CMMI architectures and components, there are many relations among CMMI practices. The organizations can be more efficiently improving their processes if they understand relationship among CMMI practices. However, there are no researches regarding this topic yet. In this paper we analyzed the relationship between Generic Practices and Specific Practices of each process areas in CMMI Maturity Level 2 by using Chi-square test of independence. As a result, we demonstrated that 10 Generic Practices in each process area are related 17 out of 48 Specific Practices (35% relationship). Using this result to improve the organization's processes, we achieved a significant improvement of 36.5% in CMMI appraisal result.