• Journal of IKEEE
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• v.14 no.2
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• pp.69-75
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• 2010

A 3D graphics pipeline is largely divided into geometry stage and rendering stage. In this paper, we propose a method that accelerates a geometry processing in multi-core GP-GPU, using dual-phase structure. It can be improved by parallel data processing using SIMD of GP-GPU, dual-phase structure and memory prefetch. The proposed architecture improves approximately 19% of performance when it use all the features.

• Communications of the Korean Mathematical Society
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• v.37 no.2
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• pp.399-407
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• 2022

In this paper, we continue to study the von Neumann regularity of rings whose essential maximal right ideals are GP-injective. It is proved that the following statements are equivalent: (1) R is strongly regular; (2) R is a 2-primal ring whose essential maximal right ideals are GP-injective; (3) R is a right (or left) quasi-duo ring whose essential maximal right ideals are GP-injective. Moreover, it is shown that R is strongly regular if and only if R is a strongly right (or left) bounded ring whose essential maximal right ideals are GP-injective. Finally, we prove that a PI-ring whose essential maximal right ideals are GP-injective is strongly π-regular.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.5
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• pp.561-568
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• 2009

To investigate the effects of garlic and medicinal plants extracts (GP) on liver function and lipid metabolism of rat administered with ethanol chronically, Sprague-Dawly male rats were fed with a basial diet (Normal), a basial diet plus ethanol (Control, 10 mL of 20% ethanol/kg b.w/day), a control diet plus 0.5% garlic and 1.0% medicinal plants extracts (GP-I), and a control diet plus 1.0% garlic and medicinal plants extracts (GP-II) for 4 weeks. Blood glucose in GP group was significantly decreased, but not significantly different between GP-I and GP-II group. Albumin content of serum was significantly increased in GP groups, while total lipid, cholesterol and triglyceride of serum were significantly decreased in GP group. Total cholesterol and triglyceride were not significantly different between GP-I and GP-II group. LDL-cholesterol in blood was decreased to 58% in GP-I group and 73% in GP-II group compared to the control group, it's contents were the lowest amounts among the normal, control and experimented groups. Lipid levels in liver of rat administered with alcohol were decreased in GP group and significantly different in GP-II group. GOT and r-GTP activities were significantly higher in control than normal group, while GPT and ALP activities were not significant in groups administered with alcohol. Activities of GOT, GPT and r-GTP were significantly lower in GP group than control group, while ALP activity was not significant in all groups. TBARS contents were not significant in serum, but it's contents in liver were significantly decreased in GP groups than control group. DPPH radical scavenging ability in serum and liver was significantly increased in GP groups. These results indicate that garlic and medicinal plants extracts were effective in improving and protecting liver disorder induced from long-term alcohol consumption.

• Journal of the Korean Mathematical Society
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• v.47 no.1
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• pp.215-222
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• 2010

A T$_1$ topological space X is called an almost GP-space if every dense G$_{\delta}$-set of X has nonempty interior. The behaviour of almost GP-spaces under taking subspaces and superspaces, images and preimages and products is studied. If each dense G$_{\delta}$-set of an almost GP-space X has dense interior in X, then X is called a GID-space. In this paper, some interesting properties of GID-spaces are investigated. We will generalize some theorems that hold in almost P-spaces.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2008.04a
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• pp.294-298
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• 2008

이메본 논문은 GP 트리의 노드포화도를 제어함으로써 트리의 구조공간에서 효율적인 개체 분포를 유도하는 GP 진화연산자를 제안한다. 특정 영역으로의 트리 개체의 분포가 성능에 미치는 영향을 검증하고 진화과정에서 나타나는 군집내의 개체 다양성과의 관계를 분석한다. 제안된 진화연산자를 회귀다항식, 멀티플렉서, 짝수 패리티의 3가지 벤치마크 문제에 대해서 실험을 하였고, 표준 GP 연산자와 비교하였다.

• Korean Journal of Mathematics
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• v.7 no.2
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• pp.215-218
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• 1999

We investigate characterizations of rings whose simple singular right R-modules are GP-injective. It is proved that if R is a semiprime ring whose simple singular right R-modules are GP-injective, then the center $Z(R)$ of R is a von Neumann regular ring. We consider the condition ($^*$): R satisfies $l(a){\subseteq}r(a)$ for any $a{\in}R$. Also it is shown that if R satisfies ($^*$) and every simple singular right R-module is GP-injective, then R is a reduced weakly regular ring.

• Proceedings of the Materials Research Society of Korea Conference
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• 2009.11a
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• pp.31.2-31.2
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• 2009

본 연구에서는 Graphene oxide를 $800^{\circ}C$, 질소분위기 하에서 환원시켜 얻은 $GP_{TR}$과 Hydrazine을 이용한 화학적 처리로 얻은 $GP_{CR}$의 분자구조를 제안하였다. 이때 grapheneoxide는 modified Hummers' method를이용하여 제조하였다. $GP_{TR}$과 $GP_{CR}$은 모두 표면에 몇몇의 oxide group이 존재하는데$GP_{TR}$은 six layer로 $C_{100}O_{3{\pm}1}$ 의 조성을 갖고 $GP_{CR}$은 three layer로 and $C_{100}O_{6.5{\pm}2}$의 조성을 갖는다. 그리고 면간간격은 $GP_{TR}$은 $3.432\;{\AA}$, $GP_{CR}$은 $3.760\;{\AA}$으로 전형적인 방법인 top downprocess로 얻은 graphene 보다 다소 크다는 것을 알 수 있다.

• Journal of Pharmaceutical Investigation
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• v.41 no.6
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• pp.381-386
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• 2011

Multi-drug resistance (MDR) has been known as a major hurdle in cancer chemotherapy. One of the most clinically significant causes of MDR was the efflux of anticancer agents mediated by p-glycoprotein (p-gp) over-expressed in MDR cancer cells. To overcome MDR, there have been several strategies such as co-administration with p-gp inhibitors and encapsulation of anticancer drugs into drug delivery systems. In the present study, curcumin was evaluated for its potential as p-gp inhibitor and MDR reversal activity when combined with paclitaxel incorporated into lipid nanoparticles (PTX/LN). Western blot assay showed curcumin did not modulate the level of p-gp expression in MCF-7/ADR which is a MDR variant of human breast cancer cell line, MCF-7, and over-expresses p-gp. However, curcumin inhibited p-gp-mediated efflux of calcein in a dose-dependent manner even though it showed lower activity compared to verapamil, a well-known p-gp inhibitor. Incorporation of paclitaxel into lipid nanoparticles partially recovered the anticancer activity of paclitaxel in MCF-7/ADR. The combined use of curcumin and PTX/LN exhibited further full reversal of MDR, suggesting susceptibility of PTX/LN to the efflux system. In conclusion, combined approach of using p-gp inhibitors and incorporation of the anticancer agents into nano-delivery systems would be an efficient strategy to overcome MDR.

• Journal of Microbiology
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• v.34 no.1
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• pp.7-14
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• 1996

Teh baculovirus gp64 glycoprotein is a major component of the envelope of budded virus (BV) and has been shown that it plays an essential role in the infection process, especially virus-cell membrane fusion. We have cloned Autographa californica Nuclear Polyhedrosis Virus (AcNPV) gp64 protein were examined for membrane fusion activity by using a synchtium formation assay under various conditions. The optimal conditions required for inducing membrane fusion are 1) form pH 4.0 to 4.8 2) 15 min exposure of cells to acidic pH 3) at least 1 .mu.g of gp64 cloned plasmid DNA per 3 * 10$^{6}$ cells 4) and an exposure of cells to acidic pH at 72 h post-transfection. In order to investigate the role of hydrophobicity of the gp64 glycoprotein for the membrane fusion, the two leucine residues (amino acid position at 229 and 230) within hydrophobic region I were substituted to alanine by PCR-derived site-directed mutagenisis and the membrane fusion activity of the mutant was anlaysed. The gp64 glycoprotein carrying double alamine substitution mutation showed no significant difference in fusion activity. This result suggested that minor changes in hydrophobicity at the amino acid position 229 and 230 does not affect the acid-induced membrane fusion activity of the gp64 glycoprotein.

• YAKHAK HOEJI
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• v.45 no.5
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• pp.545-556
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• 2001

Crude saponin fractions were isolated using non-ionic resin chromatography from Ginseng Radix Alba (PG) and Gynostemmae Herba+ (GP). These saponin fractions were orally administered to strep- tozotocin (STZ)-induced diabetic rats for 2 weeks and to high-fat diet-induced obese rats for 4 weeks. Treatment with either PG saponin or GP saponin at a dose of 1 mg/kg significantly decreased the plasma glucose level to that of glibenclamide treated or normal groups. The increased plasma triglyceride (TG) level in diabetic rats was decreased by 50% with PG or GP saponin treatment. Combined administration of PG and GP saponins with different ratios (total dose of 1 mg/kg) also had the similar effects on the blood glucose and TG levels with that of PG or GP alone. Treatments with GP (1 mg/kg) or GP (0.5 mg/kg) and PG (0.5 mg/kg) together significantly suppressed the rise in TG levels induced by high-fat diet whereas slightly suppressed the rise in the total cholesterol level. The body weight gain was also decreased both in the two saponin treated groups. These results demonstrate that either alone or mixture of PG and GP have similar degree of effects on hyperglycemia and hyperlipidemia.