• Title/Summary/Keyword: GM model

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Gene flow from herbicide resistant genetically modified rice to conventional rice (Oryza sativa L.) cultivars

  • Han, Sung Min;Lee, Bumkyu;Won, Ok Jae;Hwang, Ki Seon;Suh, Su Jeoung;Kim, Chang-Gi;Park, Kee Woong
    • Journal of Ecology and Environment
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    • v.38 no.4
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    • pp.397-403
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    • 2015
  • Rice (Oryza sativa L.) is an important feeding crop in Asia, and utilization of genetically modified (GM) rice is highly demanding. For co-existence of GM rice and non-GM rice, the proper confinement measures should be provided. Thus, we surveyed gene flow from herbicide resistant GM rice to the conventional rice cultivars in the field tests. Gene flow frequency decreased with increasing distance between the pollen donor and recipients and did not exceed more than 1% even at the nearest distance. In single recipient model plot, a maximum gene flow frequency was observed at the shortest distance and hybrid was detected up to 12 m from the pollen donor. The direction of gene was coincided with the dominant wind direction. Gene flow assessment to multiple recipient plots was conducted under the high raining season by chance, and abrupt decline of gene flow frequency and maximum distance were resulted. According to the survey results, current regulation for isolation distance is reasonable for environmental safety or for general crop production. However, we suggest an alternative measure for GM rice cultivation that should be supplemented to overcome the out of estimation and in the environment asking higher security levels.

Acute Toxicity Evaluation to Daphnia magna of Disease Resistant(OsCK1) Rice (병저항성 GM(OsCK1)벼의 물벼룩(Daphnia magna)에 대한 급성독성 평가)

  • Oh, Sung-Dug;Lee, Kijong;Park, Soo-Yun;Ryu, Tae-Hun;Suh, Sang Jae
    • Korean Journal of Environmental Agriculture
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    • v.33 no.2
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    • pp.121-128
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    • 2014
  • BACKGROUND: The disease resistant (OsCK1) rice was generated by inserting choline kinase (CK1) and phosphinothricin acetyltransferase (PAT) genes isolated from Oryza sativa and Streptomyces hygroscopicus into the genome of the rice, Nakdongbyeo. With the potential problems of safeties, the evaluations on non-target organisms are essentially required for the environmental risk assessment of genetically modified (GM) crops. In the present study, we conducted the evaluation of acute toxicity on Daphnia magna that commonly used as a model organism in ecotoxicological studies for non-target organism evaluation. METHODS AND RESULTS: Effect of acute toxicity to Daphnia magna by each concentration were investigated in the disease resistant (OsCK1) rice and non-genetically modified (non-GM) rice, Nakdongbyeo, as concentration (0, 1,000, 1,800, 3,240, 5,830, 10,500 and 20,000 mg/L). The OsCK1 rice used for the test was confirmed to express the OsCK1/PAT gene by the PCR(Polymerase chain reaction) and western blot analysis. Feeding test showed that no significant differences in cumulative immobility and abnormal response of Daphnia magna fed on OsCK1 rice or non-GM rice. The 48hr-$EC_{50}$ values showed no difference between OsCK1 rice (3,147.18 mg/L) and non-GM rice (3,596.27 mg/L). CONCLUSION: This result suggested that there was no significant difference in toxicity to Daphnia magna between OsCK1 rice and non-GM counterpart.

Tolerance Factor Analysis of Flexible Pedestrian Legform Impactor Test (신형 하부다리 모형 시험 결과에 영향을 미치는 오차 인자 분석)

  • Lee, Yonghoon;Kim, Hanseung;Jang, Sungjae
    • Journal of Auto-vehicle Safety Association
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    • v.6 no.2
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    • pp.43-48
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    • 2014
  • The flexible pedestrian legform impactor(Flex-PLI) consisting of a flexible femur and tibia will be tested for pedestrian protection by global technical regulation(GTR) within the next couple of years as a replacement for the existing transport research laboratory(TRL) legform impactor. In this study, a computer aided engineering(CAE) model was used to perform the effect analysis of each injury with regard to the changes in tolerance factors with the baseline results without tolerance. The tolerance factors were the height of impactor from ground reference line, initial velocity of impactor and rotation of impactor.

CAE-based DFSS Study for Road Noise Reduction (Road Noise 개선을 위한 CAE 기반 DFSS Study)

  • Kwon, Woo-Sung;Yoo, Bong-Jun;Kim, Byoung-Hoon;Kim, In-Dong
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2011.04a
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    • pp.735-741
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    • 2011
  • In the early phase of vehicle development, CAE is conducted as tool for vehicle performance assessment. To maintain acceptable road noise performance, solution for reduced vehicle sensitivity is required. Chassis interface dynamic stiffness characteristics are key component to isolating vibration and noise of road from the vehicle interior. This research provide how to set up the optimized dynamic characteristics under noise effect through DFSS study. CAE-based DOE is performed to build prediction math model, CMS process involves DOE to achieve very fast run times while giving results very comparable. Minimized $95^{th}$ percentile of performance distribution is applied to minimize vehicle sensitivity and road noise levels variation during the optimization process. Finally, the results of optimization were reviewed for performance and robustness.

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CAE-based DFSS Study for Road Noise Reduction (로드 노이즈 개선을 위한 전산응용해석 기반 DFSS 연구)

  • Kwon, Woo-Sung;Yoo, Bong-Jun;Kim, Byoung-Hoon;Kim, In-Dong
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.21 no.7
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    • pp.674-681
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    • 2011
  • In the early phase of vehicle development, CAE is conducted as tool for vehicle performance assessment. To maintain acceptable road noise performance, solution for reduced vehicle sensitivity is required. Chassis interface dynamic stiffness characteristics are key component to isolating vibration and noise of road from the vehicle interior. This research provide how to set up the optimized dynamic characteristics under noise effect through DFSS study. CAE-based DOE is performed to build prediction math model, CMS process involves DOE to achieve very fast run times while giving results very comparable. Minimized 95th percentile of performance distribution is applied to minimize vehicle sensitivity and road noise levels variation during the optimization process. Finally, the results of optimization were reviewed for performance and robustness.

Study on the Stability Estimation Method of Small Fishing Vessels at the Initial Design Step (초기설계 단계에서 소형 어선의 복원성 추정 방안에 관한 연구)

  • Hwe-Woo Kim;Sanghyun Kim;Sun-Woo Lee;Hyogeun Lee;In-Tae Kim
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.29 no.7
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    • pp.863-870
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    • 2023
  • Ship capsize accidents are common in coastal waters, particularly involving small fishing boats. To prevent there overturing accidents in small fishing boats, their stabilities must be assessed at the initial design step. However, the available information during the initial design step is limited, posing challenges in performing a reliable stability evaluation. Therefore, this study presents a plan to estimate the transverse metacenter (GM) of small fishing boats using parameters such as KM, KG, and TRIM that can be determined at the initial design step. Stability was evaluated by comparing GM with the minimum transverse metacenter (GMmin) specified in the standard safety evaluation criteria for fishing boats. To calculate the required trim value for hydrostatic characteristics using K-SHIP, a stability assessment program provided by the Korea Maritime Safety and Transportation Corporation, the initial trim state is estimated based on the ship lines using the commercial CFD program STAR-CCM+. GM is then calculated by assessing the hydrostatic characteristics in relation to the boat lines using K-SHIP. Furthermore, the stability of the fully loaded state is compared by subtrcating GM from GMmin. One constructed ship is designated as the standard ship, and the stability assessment method proposed in this study is applied to evaluate stability and validate its effectiveness. Consequently, the representative line of a 4.99-ton fishing boat and nine modular lines models derived from it were evaluated, ultimately identifying a relatively superior stability.

A quantitative methodology for evaluating the ship stability using the index for marine ship intact stability assessment model

  • IM, Nam-Kyun;CHOE, Hun
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.13 no.1
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    • pp.246-259
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    • 2021
  • IMO stability regulations include various stability parameters such as GM values. To assess the stability of the ships, we should check all stability parameters of the IMO requirements. However, since this process is complex, a more convenient way to evaluate stability performance is required. In this research, the index for marine ship intact stability assessment (IMSISA) model was developed to solve these problems. The IMSISA model consists of a stability index calculation module and a stability assessment module. In the stability index calculation module, ten stability parameters, including GM, were used to develop the stability index, which has the advantage of being able to quantify the ship stability. The stability assessment module uses the stability index value to determine the stability status of the ship and provides the captain with stability management guidelines. To verify the proposed model, the basic stability calculations were performed for two model ships in 32 loading situations. The proposed model was found to provide better performance in the stability assessment than the previous study. By applying the IMSISA model to the ships, the captain can assess the ship stability more quantitatively and efficiently.

Life Prediction of Hydraulic Concrete Based on Grey Residual Markov Model

  • Gong, Li;Gong, Xuelei;Liang, Ying;Zhang, Bingzong;Yang, Yiqun
    • Journal of Information Processing Systems
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    • v.18 no.4
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    • pp.457-469
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    • 2022
  • Hydraulic concrete buildings in the northwest of China are often subject to the combined effects of low-temperature frost damage, during drying and wetting cycles, and salt erosion, so the study of concrete deterioration prediction is of major importance. The prediction model of the relative dynamic elastic modulus (RDEM) of four different kinds of modified concrete under the special environment in the northwest of China was established using Grey residual Markov theory. Based on the available test data, modified values of the dynamic elastic modulus were obtained based on the Grey GM(1,1) model and the residual GM(1,1) model, combined with the Markov sign correction, and the dynamic elastic modulus of concrete was predicted. The computational analysis showed that the maximum relative error of the corrected dynamic elastic modulus was significantly reduced, from 1.599% to 0.270% for the BS2 group. The analysis error showed that the model was more adjusted to the concrete mixed with fly ash and mineral powder, and its calculation error was significantly lower than that of the rest of the groups. The analysis of the data for each group proved that the model could predict the loss of dynamic elastic modulus of the deterioration of the concrete effectively, as well as the number of cycles when the concrete reached the damaged state.

A development of multivariate drought index using the simulated soil moisture from a GM-NHMM model (GM-NHMM 기반 토양함수 모의결과를 이용한 합성가뭄지수 개발)

  • Park, Jong-Hyeon;Lee, Joo-Heon;Kim, Tae-Woong;Kwon, Hyun Han
    • Journal of Korea Water Resources Association
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    • v.52 no.8
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    • pp.545-554
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    • 2019
  • The most drought assessments are based on a drought index, which depends on univariate variables such as precipitation and soil moisture. However, there is a limitation in representing the drought conditions with single variables due to their complexity. It has been acknowledged that a multivariate drought index can more effectively describe the complex drought state. In this context, this study propose a Copula-based drought index that can jointly consider precipitation and soil moisture. Unlike precipitation data, long-term soil moisture data is not readily available so that this study utilized a Gaussian Mixture Non-Homogeneous Hidden Markov chain Model (GM-NHMM) model to simulate the soil moisture using the observed precipitation and temperature ranging from 1973 to 2014. The GM-NHMM model showed a better performance in terms of reproducing key statistics of soil moisture, compared to a multiple regression model. Finally, a bivariate frequency analysis was performed for the drought duration and severity, and it was confirmed that the recent droughts over Jeollabuk-do in 2015 have a 20-year return period.

Lifetime Risk Assessment of Lung Cancer Incidence for Nonsmokers in Japan Considering the Joint Effect of Radiation and Smoking Based on the Life Span Study of Atomic Bomb Survivors

  • Shimada, Kazumasa;Kai, Michiaki
    • Journal of Radiation Protection and Research
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    • v.46 no.3
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    • pp.83-97
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    • 2021
  • Background: The lifetime risk of lung cancer incidence due to radiation for nonsmokers is overestimated because of the use of the average cancer baseline risk among a mixed population, including smokers. In recent years, the generalized multiplicative (GM)-excess relative risk (ERR) model has been developed in the life span study of atomic bomb survivors to consider the joint effect of radiation and smoking. Based on this background, this paper discusses the issues of radiation risk assessment considering smoking in two parts. Materials and Methods: In Part 1, we proposed a simple method of estimating the baseline risk for nonsmokers using current smoking data. We performed sensitivity analysis on baseline risk estimation to discuss the birth cohort effects. In Part 2, we applied the GM-ERR model for Japanese smokers to calculate lifetime attributable risk (LAR). We also performed a sensitivity analysis using other ERR models (e.g., simple additive (SA)-ERR model). Results and Discussion: In Part 1, the lifetime baseline risk from mixed population including smokers to nonsmokers decreased by 54% (44%-60%) for males and 24% (18%-29%) for females. In Part 2, comparison of LAR between SA- and GM-ERR models showed that if the radiation dose was ≤200 mGy or less, the difference between these ERR models was within the standard deviation of LAR due to the uncertainty of smoking information. Conclusion: The use of mixed population for baseline risk assessment overestimates the risk for lung cancer due to low-dose radiation exposure in Japanese males.