• Title/Summary/Keyword: GL

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Pulmonary Fungal Infection in Patients with Healed Tuberculosis or Other Underlying Diseases (폐결핵 또는 기타 질환환자에 있어서의 폐진균증에 관한 연구)

  • Kim Sang Jae;Hong Young Pyo;Kim Sung Chin
    • Korean Journal of Microbiology
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    • v.19 no.3
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    • pp.142-152
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    • 1981
  • One hundred and thirteen healed pulmonary tuberculosis patients and 11 patients with other underlying diseases were studied for evidence of pulmonary fungal infection because of persisting hemoptysis or chronic cough. Rediological, mycological and serological investigations revealed that 54 out of 124 patients were evidently infected with one or more species of fungi. A. fumigatus was isolated from 4 out of 70 patients whose sera did not react with antigens from this fungus, while it was isolated from 43 out of 47 serological reactors to this fungus. Chest radiography showed a distinct fungus ball in a cyst of one patient and in a preformed cavity in the lung of 17 healed tuberculosis patients and two other patients. The latter two patients were infected with A.flavus. Two patients, who were under the long period of immunosuppressive therapy, apparently succumbed to invasive aspergillosia due to A.fumigatus. A single or dual infection with A. flavus, A. nidulans, A.nidulans var. latus, C. albicans, and P. boydii were noticed in some patients without mycetomal shadow on chest radiographs. Young mycelial extract (ME) of A.fumigatus detected antibody in 95.8 percent of the sera from patients infected with this fungus, while it was isolated from 43 out of 47 serological reactors to this fungus. Chest radiography showed a distinct fungus ball in a cyst of one patient and in a performed cavity in the lung of 17 healed tuberculosis patients and two other patients. The latter two patients were infected with A. flavus. Two patients, who were under the long period of immunosuppressive therapy, apparently succumbed to invasive aspergillosis due to A.fumigatus. A single or dual infection with A. flavus, A. nidulans, A. niduans var. latus, C. albicans, and P. boydii were noticed in some patients without mycetomal shadow on chest radiographs. Young mycelial extract (ME) of A.fumigatus detected antibody in 95.8 percent of the sera from patients infected with this fungus, while the commercial culture filtrate antigen (GL) yielded 78.7 per cent positive result. Culture filtrate antigen, however, was comparable with ME. There was no single antigen with which all the serum specimens reacted. Fractionation of ME resulted in a loss of some activity although it excluded substances that reacted with C-reactive protein in a loss of some activity although it excluded substances that reacted with C-reactive protein. Most reactive and specific precipitinogens distributed in the fraction (FB) which was precipitable at 75 percent saturation with ammonium sulfate and eluted in a second peak in order from gel-filtration and which contained mostly proteinic components. Glycoproteins or polysaccharides rich fractions (FA and ASI) were relatively less effective in detecting antibody. Demonstration of antibody in the serum from patients using a battery of fungal antigens and of etiologically related fungi from clinical specimens are very useful laboratory procedures for the diagnosis of pulmonary fungal infection which is a common complication of tuberculosis.

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Molecular Theory of Superplastic Deformation (초소성변형의 분자론)

  • Chang Hong Kim;Taikyue Lee
    • Journal of the Korean Chemical Society
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    • v.23 no.4
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    • pp.217-236
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    • 1979
  • The author's theory for plastic deformation was applied to superplastic alloys (Zn-Al eutectoid, Al-Cu, Pb-Sn, Sn-Bi, Mg-Al eutectics). The plastic deformation of the superplastic alloys could be described by two Maxwell models connected in parallel which represent two grain boundary flow units. The flow units are characterized by the two parameters $X_{gj}/{\alpha}_{gj}\;and\;{\beta}_{gj}$ (j=l or 2, g signifies the grain boundary) the values of which were obtained by applying our flow equation [Eq. (5)] to experiment. We confirmed that our flow equation describes the superplasticity very well. The curve of strain rate sensitivity m (=${\partial}\;In\;f/{\partial}\;In\;\dot{s})\;vs.\;-In\dot{s}$, where f and s are stress and strain rate, respectively, showed two peaks corresponding to flow unit gl and g2, the separation of the two peaks is determined by the difference between ${\beta}_{g1}\;and\;{\beta}_{g2}$. The condition of superplasticity is also determined by ${\beta}_{gj}$, which satisfies $\dot{s}_{mj}{\leqslant}1.53}{\beta}_{gj}$ [Eq.(13)], where $\dot{s}_{mj}$ is the s of the jth unit at the peak. The grain size dependence of ${\beta}_{gj}$ is described by $ln({\beta}_{gj})^{-1}$=alnx+b [Eq. (16)], where x is the grain size, and a and b are constants. The activation enthalpy for each flow unit, ${\Delta}H_{gj}^{\neq}$ was also determined from the temperature dependence of ${\beta}_{gj}$ which is proportional to the relaxation time of the j th unit. Since the superplasticity is determined by Eq. (13), and since ${\beta}_{gj}$ and ${\Delta}H_{gj}^{\neq}$ are related, we obtained the conclusion that superplasticity occurs in the system having small ${\Delta}H_{gj}^{\neq}$ values. The Aej values were equal to the activation enthalpies of grain boundary self-diffusion of the component atoms of the alloys, this accords with our proposed flow mechanism. The ${\Delta}H_{gj}^{\neq}$ value increases with grain size as expected from Eq. (16).

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Design and Implementation of Optimal Smart Home Control System (최적의 스마트 홈 제어 시스템 설계 및 구현)

  • Lee, Hyoung-Ro;Lin, Chi-Ho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.18 no.1
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    • pp.135-141
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    • 2018
  • In this paper, we describe design and implementation of optimal smart home control system. Recent developments in technologies such as sensors and communication have enabled the Internet of Things to control a wide range of objects, such as light bulbs, socket-outlet, or clothing. Many businesses rely on the launch of collaborative services between them. However, traditional IoT systems often support a single protocol, although data is transmitted across multiple protocols for end-to-end devices. In addition, depending on the manufacturer of the Internet of things, there is a dedicated application and it has a high degree of complexity in registering and controlling different IoT devices for the internet of things. ARIoT system, special marking points and edge extraction techniques are used to detect objects, but there are relatively low deviations depending on the sampling data. The proposed system implements an IoT gateway of object based on OneM2M to compensate for existing problems. It supports diverse protocols of end to end devices and supported them with a single application. In addition, devices were learned by using deep learning in the artificial intelligence field and improved object recognition of existing systems by inference and detection, reducing the deviation of recognition rates.

Service Worker Technology and Standardization (서비스워커 기술 및 표준화 동향)

  • Hwang, Hyun-seo;Kim, Sung-hyun;Jung, Yong-jin;Park, Jong-geun;Kim, Tae-yong;Kim, Tae-hwan;Moon, Il-young
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.05a
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    • pp.656-659
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    • 2015
  • Recently, due to the standard of a new browser developed by the Google and Mozilla "Service Worker", future users is expected to be able to make use of favorite Web sites offline. Google's is, Web sites have developed a standard of a new browser so as to always respond to user requests. Service Worker, websites that provide space capable of offline work to the user's browser to store various document information, to provide the necessary resources. Then, in order to greatly reduce the data exchange operations between the browser and the server, the speed of the Web page increases. Not only cooks as native app that can use the Web application offline, in that us to also further enhance the characteristics of an existing Web application that is running without installing destructive high technology. Service worker specifications, use experience of Web application is very can be improved, is an innovative technology indicates the version of the web evolve as the future of the platform. Service Worker is not included in HTML5 standard final, is currently being continued standardization. Future Service Worker technology I expect what kind of thing unfolds when applied to the Web browser.

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Inhibition of pRB Phosphorylation and Induction of p21WAF1/CIP1 Occur During cAMP-induced Growth Arrest in Human Neuroblastoma Cells (인체 신경아세포종에서 cAMP 처리에 의한 pRB의 인산화 억제 및 p21WAF1/CIP1의 유도)

  • Park, Yung-Hyun;Lee, Sang-Hyeon
    • Journal of Life Science
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    • v.13 no.5
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    • pp.642-650
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    • 2003
  • To develop a new approach to the treatment of neuroblastoma cells we evaluated the effect of cAMP on the Ewing's sarcoma cell line CHP-100. We observed that the proliferation-inhibitory effect of cAMP analogs was due to cell cycle arrest and induction of apoptosis, which was confirmed by observing the morphological changes and DNA fragmentation. DNA flow cytometric analysis revealed that cAMP arrested the cell cycle progression at the G1 phase, which effects were associated with inhibition of phosphorylation of retinoblastoma protein (pRB) and enhanced binding of pRB and the transcription factor E2F-1. cAMP also suppressed the cyclin-dependent kinase (Cdk) 2 and cyclin E-associated kinase activity without changes of their expressions. Furthermore, cAMP induced the levels of Cdk inhibitor $p21^{WAF1/CIP1$ expression and p21 proteins induced by cAMP were associated with Cdk2. Overall, our results identify a combined mechanism involving the inhibition of pRB phosphorylation and induction of p21 as targets for cAMP, and this may explain some of its anti-cancer effects.

Elicitation of Indole-3-ylmethyl Glucosinolate Biosynthesis in Turnip Culture Cells and Their Relationship with Plant Resistance to Botrytis cinerea (잿빛곰팡이병 추출물을 이용한 순무배양세포의 Indole-3-ylmethyl glucosinolate의 생합성유도와 병원성연구)

  • Kwon, Soon Tae;Zhang, Vivian
    • Korean Journal of Plant Resources
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    • v.30 no.5
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    • pp.542-548
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    • 2017
  • Two different races of Botryris cinerea were selected by the response of plant leaves to the pathogen infection. Based on lesion size of the pathogen on the leaves, turnip showed susceptible response to 'Grape-01' race, and resistant to 'Orange' race. Turnip leaves infected with resistant pathogen race, "Orange", showed significantly higher content of indole-3-ylmethyl glucosinolate (I3M) than those infected with susceptible race, 'Grape-01'. Contents of I3M in the leaves with resistant 'Orange' race was 2.5 times as high as that in uninfected leaves, whereas I3M in the leaves infected with susceptible 'Grape-01' race showed lower content than in untreated leaves. Growth of turnip suspension cells was significantly inhibited by the treatment of MeOH extract or water extract of 'Orange' race as compared with the treatment of susceptible race, 'Grape-01'. Treatment of MeOH or water extract from 'Orange' race to turnip suspension cells, strongly inhibited cell viability up to 22.7% or 16.5%, respectively. However, plant cells treated with MeOH or water extract from resistant race, 'Orange' showed higher I3M content than that from susceptible race, 'Grape-01'. These results suggest that accumulation and degradation of I3M glucosinolate in turnip cells closely related to the resistance and susceptibility of turnip cells to Botrytis cinerea.

QTLs analysis associated with a major agronomic traits in hanareum2×unkwang rice recombinant inbred line

  • Lee, Ji Yoon;Cho, Jun Hyeon;Kang, Ju Won;Shin, Dong Jin;Kim, Tae Heon;Song, You Chun;Han, Sang Ik;Park, Dong Soo;Son, Young Bo;Cho, Su Min;Oh, Myeong Kyu
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.101-101
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    • 2017
  • This study was carried out to improve yield potential of Tongil type rice variety based on QTLs analysis associated with yield component using a total of 386 rice recombinant inbred lines (RILs) derived from a cross between Tongil type high yield variety "Hanareum2" and Japonica variety "Unkwang". 384 SNP markers were used, and 241 of them (62.6%) were polymorphic between Hanareum2 and Unkwang. One hundred forty-four QTLs in 11 traits, such as heading days, were detected. Most of them were 21 QTLs associated with 1000 grain weight and the least was 8 QTLs associated with panicle number. The QTL, qDTH3-2 associated with days to heading was identified to delay heading date for 2.4~2.6 day. Eleven QTLs were associated with culm length. The QTL, qCL1-2 on chromosome 1, was identified to decrease culm length. A total of 16 QTLs were detected for panicle length. Three QTLs, qPL3, qPL6, and qPL7-1 were increased panicle length. Seven QTLs related to panicle number except qPN7 were increased the number of panicle. Four QTLs related to grain number per panicle, qGNP2-1, qGNP6, and qGNP7, were increased the number of grains. Three QTLs associated with grain filling rate, qGFR1, qGFR2-2, and qGFR7-1 were increased grain filling rate. Twelve QTLs associated with 1,000 grain weight. were increased the grain weight. Fourteen QTLs were identified associated with grain length. 10 QTLs, such as qGL1-1, were increasing grain. Fifteen QTLs associated with grain width were detected. The 8 QTLs, such as qGW1-1, were elongated grain width. Seventeen QTLs were associated with grain thickness, and ten QTLs of them were increased grain thickness. We need further study to develop introgression lines of each QTL to improve yield potential of Tongil type rice variety.

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Development of Aerodynamic Shape Optimization Program for Horizontal Axis Wind Turbine Blade (수평축 풍력 블레이드 공력 형상 최적화 설계 프로그램 개발)

  • Yoo, Cheol;Son, Eunkuk;Hwang, Sungmok;Choi, Jungchul;Lee, Jin-Jae;Kim, Seokwoo;Lee, Gwang-Se
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.12
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    • pp.9-16
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    • 2017
  • In this paper, the aerodynamic design process of wind turbine blades is established. The optimization design strategy is presented and the constraints that must be reviewed during the aerodynamic design process are summarized. Based on this, this study developed a BEMT-based aerodynamic optimal design program that can be applied easily to actual work, not only for research purposes, but also can be integrated from the initial concept design stage to the final 3D shape detail design stage. The developed program AeroDA consisted of a concept design module, basic design module, optimal TSR module, local shape optimization module, performance analysis module, design verification module, and 3D shape generation module. Using the developed program, an improved design of the 5MW blade by NREL was made, and it was confirmed that this program could be used for design optimization. In addition, a 10kW blade aerodynamic design and turbine detailed performance analysis were carried out, and it was verified by a comparison with the commercial program DNVGL Bladed.

Evaluation of corrosion resistance for various coated steel sheets by different types of corrosion test method (내식성 코팅 강재의 부식시험 종류 별 내식성 비교 평가)

  • Park, Jae-Hyeok;Hwang, Seong-Hwa;Park, Jun-Mu;Eom, Jin-Hwan;Yun, Yong-Seop;Lee, Myeong-Hun
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2017.05a
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    • pp.163-163
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    • 2017
  • 철강재는 대량 생산이 가능하여 경제성이 뛰어나고 기계적 성질도 우수하여 다양한 산업 분야에서 널리 사용되고 있다. 그러나 철강재는 부식 환경에 취약하기 때문에 그 용도에 따라 다양한 내식성을 부여하는 표면처리를 적용하고 있다. 이러한 철강재에 대한 내식성 표면처리로는 용융아연도금(HDG)과 용융알루미늄도금(HDA)이 우수한 내식성과 다양한 특성으로 널리 사용되고 있으며 아연과 알루미늄을 접목시킨 갈바륨(GL)도금 또한 우수한 내식성 코팅으로 알려져 있다. 또한 최근에는 기존 용융아연도금에 알루미늄(Al) 과 마그네슘(Mg)을 첨가한 3원계 도금강판이 개발되어 기존 용융도금강판 대비 고내식 코팅으로 알려져 있으며 그 적용은 점차 확대되고 있는 추세이다. 일반적으로 이와 같은 강판소재의 내식성 평가에 대해서는 실제 사용할 환경에 폭로하여 비교-시험 하는 것이 가장 확실하고 신뢰도가 높은 방법이다. 그러나 이러한 방법은 경우에 따라 수년에서 수십년에 이르는 장시간이 소요된다. 그러므로 이 방법을 대체하기 위한 각종 가속적 부식 시험들이 널리 적용되고 있다. 즉, 그 목적이나 용도에 따라 염수분무(SST), 침지(Immersion) 및 전기화학적 분극(Polarization) 등 실내에서 부식 시험 하는 방법이 사용되고 있다. 한편, 이러한 부식 가속 시험들은 실제 외부에서 폭로 시험한 결과와의 상관성이 불명확한 경우가 많아 종종 해석에 어려움을 갖고 있는 실정이다. 또한 이 시험 방법들은 동일 재료를 시험하더라도 시험방법의 차이에 따라 부식요인이나 해석방법이 다르므로 인해 그 내식성 결과가 다르게 나타날 수 있다. 그 중 시험목적에 따라 전기화학적 분극 또는 임피던스 분광법(EIS)과 건조 및 습윤 등의 부식 환경 인자들을 적용한 복합부식시험(CCT) 방법은 근사한 대안으로 주목받고 있다. 하지만 이들 시험 또한 실제 부식 환경과는 여러 환경 및 요인들이 다르기 때문에 그 시험방법에 따라 목적하는 시험 결과가 상이하게 나타날 수 있어 해석-평가 하기에 종종 곤란을 갖는다. 이에 따라 최근에는 재현성이 우수하고 실제 부식 환경을 유사하게 모사할 수 있는 내식성 시험과 해석-평가에 대한 내용이 주요한 과제로 사료되고 있다. 본 연구에서는 다양한 내식성 코팅 강판소재들에 대하여 염수분무(SST), 복합부식(CCT), 갈바닉 시험, EIS 시험을 통하여 부식시험 종류 및 시험 환경, 코팅 소재 별 부식경향을 비교-분석하고자 하였다. 또한 이들 부식 진행과정에서는 미세구조관찰(SEM), 결정구조 분석(XRD) 및 원소조성 분석(EPMA)을 통해 다양한 조건에 따른 강판소재들의 부식경향을 비교-평가하고, 실제 환경과의 상관성 및 가속관계를 도출하고자 하였다.

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Gastropericardial Fistula as a Late Complication after Esophagectomy with Esophagogastrostomy, A Case report (식도 절제술 및 위-식도문합술 후 만기 합병증으로 발생한 위-심막루)

  • Kim, Tae-Gyun;Kang, Jung-Ho;Chung, Won-Sang;Kim, Young-Hak;Kim, Hyuck;Jee, Heng-Ok;Lee, Chul-Bum;Ham, Shi-Young;Jeon, Seok-Chol
    • Journal of Chest Surgery
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    • v.35 no.3
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    • pp.248-250
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    • 2002
  • A 56 year-old man complaining of dry cough, dyspnea, chest pain, fever, and chills was admitted to the emergency room. The patient had a history of esophagectomy and esophagogastrostomy and subsequent radiotherapy because of an esophageal cancer. After the emergency echocardiography revealed a small amount of pericardial effusion and pneumopericardium. Upper GI contrast study showed a fistulous tract between the stomach and the pericardium, and an emergency operation was done under the diagnosis of gastropericardial fistula. The patient expired postoperative seven days later. Gastropericardial fistula caused by a peptic ulcer perforation after the esophagectomy and esophagogastrostomy operation is a very rare complication and brings forth a disastrous result. Early detection using the chest radiography, electrocardiogram, upper Gl study, echocardiography and a review of physical examination, and an immediate treatment are therefore mandatory.