• Journal of Haehwa Medicine
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• v.13 no.2
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• pp.147-168
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• 2004

Objectives & Methods: We investigated 36 books to study etiology, pathology and acupuncture & Moxibustion treatment of Gak-Gi Result and Conclusion 1. Gak-Gi is a disease of legs. In the past, it was called Wan-poong(緩風) or Gueol(厥). Currently it is divided into two kinds; the Seup-Gak-Gi(Damp Gak-Gi) in which the legs swell; The Gun-Gak-Gi(Dry Gak-Gi) in which the legs do not swell. 2. Gak-Gi may be caused by exogenous wind, coldness, dampness and Excess of phlegm or damp-heat. It also can be caused by weakness of vital energy(Myungmoon fire;命門火), kidney Yin deficiency and vital energy deficiency in the Stomach and Spleen. 3. Gak-Gi-Pal-Hyul(Eight acupoints for Gak-Gi; 脚氣八穴) are GB31(Poonsi; 風市), ST32(Bok-to; 伏兎), ST35(Dok-bi; 犢鼻), Nae-seul-an(Extra point; 內膝眼), ST36(Chok-samni; 足三里) ST37(Sang-goho; 上巨虛) ST39(Hagoho; 下巨虛) GB41 (Choc-imup; 足臨泣) 4. Treatment plans for Gak-Gi are removing the exogenous wind, coldness and dampness, regulating meridians, alleviating the pain and swelling, more importantly, tonifying vital energy and nourishing Spleen and Stomach. 5. Three out of Eight acupoints for Gak-Gi, ST36(Chok-samni; 足三里), ST37(Sang-goho; 上巨 虛), ST39(Hagoho; 下巨虛) are Lower sea points of Fu organs( Stomach, Large Intestine, Small Intestine). Five out of Eight acupoints for Gak-Gi, ST32(Bok-to; 伏兎), ST35(Dok-bi;犢鼻) are onthe Stomach meridian, and Nae-seu1-an(Extra point; 內膝眼) is on the Spleen meridian. This result indicates that regulation of Middle-cho(中焦) is important in the treatment for Gak-Gi.

• Korean Journal of Psychosomatic Medicine
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• v.1 no.1
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• pp.75-80
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• 1993

To understand and evaluate the patients who were referred for psychiatric consultation from medical departments, the authors reviewed the concept of disease, psychological reaction to disease, problems on psychiatric diagnosis and evaluation which were encountered at the medical ward. In addition, we reviewed what psychiatrists should do during consultation.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.1 no.1
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• pp.62-63
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• 2001

• Nuclear Medicine and Molecular Imaging
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• v.43 no.4
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• pp.363-365
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• 2009

Kikuchi's disease is a self-limiting benign disease characterized by cervical lymphadenopathy, but it can be mistaken for malignant disease, and when involved lymph nodes are unusually located, diagnosis can be more difficult. The authors report the case of a 19-year-old man with Kikuchi's disease, who had isolated intra-abdominal lymphadenopathy and increased 18-fluoro-deoxyglucose (FDG) uptake in positron emission tomography-computed tomography (PET-CT). Although its incidence is extremely rare, intra-abdominal Kikuchi's disease with increased FDG uptake in PET-CT image should be considered in the differential diagnosis when constitutional symptoms mimic those of malignant lymphoma.

• Genomics & Informatics
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• v.19 no.2
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• pp.14.1-14.6
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• 2021

Coronavirus disease 2019 (COVID-19) is an on-going pandemic disease infecting millions of people across the globe. Recent reports of reduction in antibody levels and the re-emergence of the disease in recovered patients necessitated the understanding of the pandemic at the core level. The cases of multiple organ failures emphasized the consideration of different organ systems while managing the disease. The present study employed RNA sequencing data to determine the disease associated differentially regulated genes and their related protein interactions in several organ systems. It signified the importance of early diagnosis and treatment of the disease. A map of protein interactions of multiple organ systems was built and uncovered CAV1 and CTNNB1 as the top degree nodes. A core interactions sub-network was analyzed to identify different modules of functional significance. AR, CTNNB1, CAV1, and PIK3R1 proteins were unfolded as bridging nodes interconnecting different modules for the information flow across several pathways. The present study also highlighted some of the druggable targets to analyze in drug re-purposing strategies against the COVID-19 pandemic. Therefore, the protein interactions map and the modular interactions of the differentially regulated genes in the multiple organ systems would incline the scientists and researchers to investigate in novel therapeutics for the COVID-19 pandemic expeditiously.

• Journal of the Korean Society of Radiology
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• v.84 no.3
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• pp.757-762
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• 2023

First described in 1930 as a lipoid granulomatosis, Erdheim-Chester disease (ECD) is a rare histiocytosis encompassing a group of disorders caused by overproduction of histiocytes, a subtype of white blood cells. This disease most commonly involves the bones and can affect organs in the abdomen; however, biliary involvement is rarely reported. We report a case of ECD with biliary involvement, which rendered it difficult to radiologically distinguish ECD from immunoglobulin G4-related disease.

• Mycobiology
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• v.42 no.1
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• pp.79-81
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• 2014

From June to October 2012, severe outbreaks of rust disease on Solidago virgaurea var. gigantea were observed in 5 different regions of Ulleung-do, Korea. Typical rust symptoms appeared as yellow spots, uredinia on leaves, and massive urediniospores covering the entire plant. Severely infected plants became discolored and died. On the basis of its morphological and molecular characteristics, the causal agent was identified as Coleosporium asterum. This pathogen has been reported as rust disease on S. virgaurea in the Canada and United States. In Korea, rust disease on S. virgaurea var. gigantea was reported as Uromyces rudbeckia in 1992. To the best of our knowledge, C. asterum is a novel rust pathogen on S. virgaurea var. gigantea in Korea.

• The Plant Pathology Journal
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• v.18 no.2
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• pp.106-108
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• 2002

Severe spotted lesions were observed on tulip plants grown in Asan, Yongin, and Icheon areas in Korea during a disease survey in 2000 and 2001. Diseased plants with severe symptoms were blighted and rotted at the late stage of disease development. A total of 15 isolates was obtained from the infected plant parts of tulip. All the isolates were identified as Botrytis tulipae based on their morphological and cultural characteristics. Three isolates of B. tulipae were tested for their pathogenicity to tulip by artificial inoculation. Spotted lesions similar to those observed in the fields were induced on tulip leaves. This is the first report of tulip fore disease caused by B. tulipae in Korea.

• Genomics & Informatics
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• v.10 no.4
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• pp.234-238
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• 2012

Genetic epidemiology studies have established that the natural variation of gene expression profiles is heritable and has genetic bases. A number of proximal and remote DNA variations, known as expression quantitative trait loci (eQTLs), that are associated with the expression phenotypes have been identified, first in Epstein-Barr virus-transformed lymphoblastoid cell lines and later expanded to other cell and tissue types. Integration of the eQTL information and the network analysis of transcription modules may lead to a better understanding of gene expression regulation. As these network modules have relevance to biological or disease pathways, these findings may be useful in predicting disease susceptibility.

• Journal of Oriental Neuropsychiatry
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• v.17 no.1
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• pp.145-152
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• 2006

The purpose of this study was to investigate the clinical application of oriental medical therapy to Pick's disease We treated the patient with oriental medical therapy. The recovery of the dementia was evaluated by Korean-Mini Mental State Examination(MMSE-K), Korean-dementia Rating Scale(K-DRS) & Barthel ADL Index.(ADL) The applicability of oriental medical therapy has positive effects on the patient with Pick's disease. The Sum of MMSE-K score was increased. K-DRS & ADL were also promoted.