• 제목/요약/키워드: GEE

검색결과 2,027건 처리시간 0.058초

Patient and Clinical Variables Account for Changes in Health-related Quality of Life and Symptom Burden as Treatment Outcomes in Colorectal Cancer: A Longitudinal Study

  • Hung, Hsiu-Chi;Chien, Tsui-Wei;Tsay, Shiow-Luan;Hang, Hewi-Ming;Liang, Shu-Yuan
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권3호
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    • pp.1905-1909
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    • 2013
  • Objective: The aim of the current study was to evaluate changes in treatment outcomes in terms of health-related quality of life (HRQoL) and symptom burden at zero, one, three, and six months after an initial diagnosis of colorectal cancer. The demographic and clinical characteristics that account for outcome changes in patients were investigated using a repeated measures framework. Methods and Materials: A cohort study was performed of 134 colorectal cancer patients followed from diagnosis to 6 months post-treatment in Central Taiwan. HRQoL and symptoms were assessed at diagnosis and one, three, and six months thereafter. The Functional Assessment of Cancer Therapy-Colon (FACT-C) questionnaire, VAS pain, and the Memorial Symptom Assessment Scale (MSAS) were used for data collection. A generalized estimating equation (GEE) was applied for statistical analysis. Results: The majority of the patients were male (55%) and married (91.5%). The mean age was 60.4 years (SD = 11.71). Most were diagnosed stage III and IV colorectal cancer (54.5%). All underwent surgery; some also received chemotherapy (CT) or concurrent chemoradiation therapy (CCRT). The results of the GEE showed that overall, the HRQoL, pain, and symptoms of the patients significantly improved over the treatment period. Patients with stage IV disease who had received surgery and CCRT showed the worst HRQoL. Females, patients with comorbidity, and stage IV patients had higher pain scores over time. Female and stage IV patients had more severe physical symptoms, whereas stage II and IV patients had worse psychological symptoms over time. Conclusion: The patients' HRQoL, pain, and symptoms significantly improved over the 6-month treatment period. Certain patient and clinical variables accounted for changes in treatment outcomes regarding HRQoL and symptom burden in colorectal cancer patients.

도시 근로자 가구의 빈곤 추이(推移)와 원인에 관한 연구: 조세와 이전소득의 빈곤완화효과를 포함하여 (Trends and Causes of Poverty among Urban Wage Earners' Households)

  • 김교성
    • 한국사회복지학
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    • 제59권2호
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    • pp.143-169
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    • 2007
  • 본 연구의 목적은 1995년부터 2005년까지 도시근로자 가구의 빈곤실태와 변화추이, 빈곤가구의 특성, 그리고 빈곤의 원인을 규명하고, 공 사적 이전소득과 조세의 빈곤완화 효과를 평가하여, 우리나라 빈곤문제에 대한 전반적인 이해를 도모하고, 그에 기초하여 보다 바람직한 정책적 대안을 모색하는데 있다. 이를 위해 도시가계조사의 연간 원자료를 분석의 자료로 활용하였으며, 종단자료에 대한 분석을 위해 GEE(Generalized estimating equation) 회귀분석을 실시하였다. 분석의 결과, 가장 중요한 사실 가운데 하나는, 경제위기를 경험하면서 그 규모와 심도 차원에서 심각했던 도시 근로자 가구의 빈곤 문제가, 이후 크게 개선되지 못하고, 오히려 더욱 악화되고 있다는 점이다. 또한 여성빈곤, 노령빈곤, 저학력 가구주 가구의 빈곤 등, 전통적인 빈곤가구의 특성이 확인되었으며, 이들 취약집단의 빈곤화 현상도 시간이 경과함에 따라 더욱 심화되는 모습을 보이고 있다. 그리고 임시 일용직, 단순노무직, 1차 산업과 민간서비스업 종사자 가구의 빈곤화 현상도 상대적으로 높게 나타나, 저임금과 고용불안정이 빈곤의 주된 원인임을 추정할 수 있다. 이러한 빈곤 가구의 특성은 빈곤의 원인에 대한 분석에서도 다시 한번 확인된다. 그리고 정부의 조세와 공적이전소득의 빈곤완화 효과는 이전의 시기에 비해 크게 확대되었지만, 그 상대적인 효과는 서구의 복지선진국과 비교해 볼 때, 아직 초보적인 단계에 머물러 있는 낮은 수준이다.

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Health-Related Quality of Life of Breast Cancer Patients in iran: Pooled Analysis using Generalized Estimating Equations

  • Kiadaliri, Aliasghar Ahmad;Bastani, Peivand;ibrahimipour, Hossein
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권3호
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    • pp.941-944
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    • 2012
  • Objective: The aim of current study was to evaluate the changes of health-related quality of life (HRQoL) and its clinical, demographic and socioeconomic determinants during chemotherapy and 4 months follow-up in women with breast cancer using a repeated measures framework. Methods and Materials: A double blind cohort study was performed in 100 breast cancer patients given fluorouracil, doxorubicin and cyclophosphamide (FAC) or docetaxel, doxorubicin, cyclophosphamide (TAC) in south of Iran. HRQoL was assessed at baseline, end of chemotherapy and four months thereafter using the QLQ-C30 questionnaire from European Organization for Research and Treatment of Cancer (EORTC). Generalized estimating equations (GEE) was applied for statistical analysis. Results: The mean of age at baseline was $48.5{\pm}10.6$. 70% and 14% of patients were married and smokers, respectively, and 20% suffered from another disease besides breast cancer. The results of GEE showed that after control for baseline scores, the HRQoL significantly improved over time. Although, the patients in FAC group had higher scores than the TAC group, the differences also diminished over time. Smoking, marital status and having child affected some scales of HRQoL. None of other variables were significantly related to HRQoL. Conclusion: Although patients in TAC groups had lower level of HRQoL over 8 months follow up, they experienced faster improvement than the FAC group. This implies that in long-term, improvements in TAC group are higher than FAC. Having children was positively correlated with HRQoL. Generally, there were no demographic and socio-economic differences in HRQoL in these patients between the chemotherapeutic regimens.

메타확률 프런티어를 사용한 CO2의 국제환경효율 (International Environmental Efficiency with CO2 Using Meta Stochastic Frontier Analysis)

  • 리즈야오;강상목
    • 자원ㆍ환경경제연구
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    • 제30권3호
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    • pp.471-501
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    • 2021
  • 본 연구는 투입물 거리함수에 의한 메타확률 프런티어 방법을 사용하여 1998년부터 2018년까지 4개 소득그룹의 이산화탄소 기준의 환경효율성(EE)을 측정하였다. 에너지 소비가 이산화탄소 배출을 증가시키고, 노동과 자본투입을 증가하면 이산화탄소 배출을 감소시킬 것임을 보여주고 있다. 또한 그룹환경효율성(GEE: Group Environmental Efficiency), 메타환경효율성(MEE: Meta Environmental Efficiency) 및 환경격차(EGR: Environmental Gap Ratio)를 비교하였다. 결과는 GEE가 과대평가되고 MEE는 이 기간 동안 하향세를 보여주고 있다. 중하위 소득그룹의 EGR은 가장 높았다. 그리고 고소득 및 중상위 소득그룹의 MEE 및 EGR이 상대적으로 낮았다. 환경효율성을 높이려면 화석에너지를 저감하고 기준 환경 문제를 해결하는 방법이 보다 과학적이고 기술적인 방법을 찾아 필요가 있음을 시사한다.

Google Earth Engine의 Sentienl-1 SAR를 활용한 남극 빙설 면적 변화 모니터링 (Assessment of Antarctic Ice Tongue Areas Using Sentinel-1 SAR on Google Earth Engine)

  • 이나미;김승희;김현철
    • 대한원격탐사학회지
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    • 제40권3호
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    • pp.285-293
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    • 2024
  • 본 연구는 Google Earth Engine을 활용하여 Sentinel-1 Synthetic Aperture Radar 영상을 통해 남극 Campbell Glacier Tongue (CGT)와 Drygalski Ice Tongue (DIT)의 면적 변화를 2016년부터 2024년까지 모니터링하였다. Otsu 기법과 Simple Non-Iterative Clustering (SNIC) 클러스터링 기법을 사용하여 빙설과 해양을 구분하고 월평균 영상을 통해 빙설 탐지 오류를 줄였다. 분석 결과 CGT는 주기적인 붕괴로 인하여 약 26% 감소하였고 DIT는 전반적으로 증가하다가 최근 급격한 감소를 보였다. Sentinel-2 광학 영상과 비교한 결과 높은 탐지 정확성을 보여 제안된 방법의 신뢰성을 입증하였으며, 본 연구는 남극 빙설과 빙붕의 장기 모니터링에 기여할 것으로 기대된다.

박근형 연극에 나타난 가족 이데올로기에 대한 비판적 인식 (A Study on Critical Understanding of Family Ideologies in Geun Hyung Park's Plays)

  • 김숙경
    • 한국연극학
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    • 제48호
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    • pp.85-125
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    • 2012
  • Geun Hyung Park is one of the playwrights who consistently pursues his unique world of play. One of the characteristics that is constantly discovered in Park's plays is the motif of 'family.' Park chooses family as the motif in most of his work. Park particularly emphasizes 'family life' rather than 'individual life' to focus on the internal problems of families. Therefore, the motif of family in Park's plays takes a very important position in the content and theme. The Korean society imposes unique value on families and possesses a strictly obstinate family ideology. Park observes distorted family relations or individuals who cannot be happy within their families to identify the problems related to the family ideology that is deeply rooted in the Korean society. This is one of the important backgrounds for which Park is constantly dealing with 'family life.' This study selected five of Park's most famous plays to specifically examine Park's critical understanding of family ideology. First, his criticizes extreme family egoism by depicting a family that cannibalizes people to keep the family full. Park chooses 'absurd time and space' and the extreme subject of 'human flesh' to warn his audiences about the awful consequences of family egoism. His , which is the only piece that deals with family history among the five pieces selected, criticizes Korea's unique family-centered ideology by humorously depicting the history of the Cho family that is all about maintaining and worshipping the its clan. He reveals the unethical and hypocritical attitudes of the Cho family for the audiences to reconsider the family-centered ideology of the Korean society. In , he talks about the son and the father who lose his ethical authority and fail to perform his paternal responsibilities to criticize the traditional family ideology of patriarchism and suggests the pessimistic future of patriarchism. contrasts a blood-related family with an irresponsible father and a quasi-family to criticize the identity of blood-related families. In , Park depicts a 'smelly house' of a family in agonizing relations to deny the family myth and the maternal myth. He clearly shows how the ideals of family myth and maternal myth are distant from the reality. In result of this study, Park's criticism of family ideology appears in various forms. He comprehensively criticizes both the general family problems and the unique family issues of Korea. The family ideology of Korea is currently undergoing a radical change. It has been long since the traditional family ideologies have exposed problems to show the signs of crisis. Also, there have emerged various forms of families, including single-parent families, one-person families, adoption families, and multi-cultural families. In this respect, Park's critical understanding of family ideologies allows you to see the obvious family forms from a new perspective and greatly contributes to awakening the essential questions about families. Park's work is noticeable among the various artistic and literature pieces that deal with family issues because of his extraordinary skills to capture the key issues inherent in the problems of family ideologies.