• 천문학회지
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• 제46권4호
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• pp.173-181
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• 2013

We trace the dynamical evolution of dark matter (DM) content in NGC 6397, one of the native Galactic globular clusters (GCs). The relatively strong tidal field (Galactocentric radius of ~ 6 kpc) and short relaxation timescale (~0.3 Gyr) of the cluster can cause a significant amount of DM particles to evaporate from the cluster in the Hubble time. Thus, the cluster can initially contain a non-negligible amount of DM. Using the most advanced Fokker-Planck (FP) method, we calculate the dynamical evolution of GCs for numerous initial conditions to determine the maximum initial DM content in NGC 6397 that matches the present-day brightness and velocity dispersion profiles of the cluster. We find that the maximum allowed initial DM mass is slightly less than the initial stellar mass in the cluster. Our findings imply that NGC 6397 did not initially contain a significant amount of DM, and is similar to that of NGC 2419, the remotest and the most massive Galactic GC.

• Journal of Korean Neurosurgical Society
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• 제48권2호
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• pp.99-104
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• 2010

Objective : We conducted this study to evaluate the clinical impact of early enteral nutrition (EN) on in-hospital mortality and outcome in patients with critical hypertensive intracerebral hemorrhage (ICH). Methods : We retrospectively analyzed 123 ICH patients with Glasgow Coma Scale (GCS) score of 3-12. We divided the subjects into two groups : early EN group (< 48 hours, n = 89) and delayed EN group ($\geq$ 48 hours, n = 34). Body weight, total intake and output, serum albumin, Creactive protein, infectious complications, morbidity at discharge and in-hospital mortality were compared with statistical analysis. Results : The incidence of nosocomial pneumonia and length of intensive care unit stay were significantly lower in the early EN group than in the delayed EN group (p < 0.05). In-hospital mortality was less in the early EN group than in the delayed EN group (10.1% vs. 35.3%, respectively; p = 0.001). By multivariate analysis, early EN [odds ratio (OR) 0.229, 95% CI : 0.066-0.793], nosocomial pneumonia (OR = 5.381, 95% CI : 1.621-17.865) and initial GCS score (OR = 1.482 95% CI : 1.160-1.893) were independent predictors of in-hospital mortality in patients with critical hypertensive ICH. Conclusion : These findings indicate that early EN is an important predictor of outcome in patients with critical hypertensive ICH.

• BMB Reports
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• 제29권2호
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• pp.127-132
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• 1996

Germinal centers (GCs) are formed in peripheral lymphoid tissues in response to protein antigens. In order to see if immunoglobulin isotype switching takes place in GC B-cells, we isolated GC B-cells (PNA positive cells) from mouse popliteal lymph nodes by a flow cytometer after the staining of lymph node cells with PNA-FITC and anti-B220-PE, and determined the expression of ${\gamma}1$ germline transcript and ${\gamma}1$ mRNA by RT-PCR. ${\gamma}1$ germline transcript and ${\gamma}1$ mRNA were amplified specifically in cDNAs from hybridoma expressing IgG1 or splenocytes stimulated LPS plus IL-4. Germinal center B-cells formed in popliteal lymph nodes of mice immunized with chicken ovalbumin were isolated 7 days after immunization. We sorted GC B-cells five times. Immunoglobulin ${\gamma}1$ germline transcripts were expressed in germinal center B-cells in three out of five sorts whereas two out of five sorts did not express ${\gamma}1$ germline transcripts in GC B-cells. The contents of GC B-cells ranged from 5 to 7% of total lymph node cells in most flow cytometric analyses but those of two sorted cells which did not express ${\gamma}1$ germline transcripts were out of normal range. These results imply that isotype switching of immunoglobulins may take place in GCs.

• Journal of Power Electronics
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• 제18권4호
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• pp.1245-1254
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• 2018

The stability of a grid-connected system (GCS) has become a critical issue with the increasing utilization of renewable energy sources. Under grid faults, however, a grid-connected inverter cannot work efficiently by using only the traditional droop control. In addition, the unbalance factor of voltage/current at the common coupling point (PCC) may increase significantly. To ensure the stable operation of a GCS under grid faults, the capability to compensate for grid imbalance should be integrated. To solve the aforementioned problem, an improved voltage-type grid-connected control strategy is proposed in this study. A negative sequence conductance compensation loop based on a positive sequence power droop control is added to maintain PCC voltage balance and reduce grid current imbalance, thereby meeting PCC power quality requirements. Moreover, a stable analysis is presented based on the small signal model. Simulation and experimental results verify the aforementioned expectations, and consequently, the effectiveness of the proposed control scheme.

• Journal of Korean Neurosurgical Society
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• 제40권4호
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• pp.234-238
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• 2006

Objective : The operative indications on cerebellar hemorrhage have been controversial especially when the patient condition is grave. Therefore we investigated whether it can be justifiable if we perform the surgery in poor clinical grade. Methods : Clinical records and computerized tomography[CT] films of the 89 patients, who were undergone hospital treatment due to spontaneous cerebellar hemorrhage between May 1997 and May 2004, were retrospectively researched. Results : The study population consisted of 36 males and 53 female patients. The mean age was 65years [range $23{\sim}89$]. As a result of treatment, the patients, whose Glasgow coma scale[GCS] score were higher, showed better outcomes [p=0.001]. 13 patients [14.6%] were below 5 in GCS score and 10 patients of these were operated. Among 10 patients, 4 patients [40%] showed good outcome and 5 patients [50%] had been dead. 3 patients [60%] of these dead patients had the findings of intraventricular hemorrhage, fourth ventricular obliteration and hydrocephalus in CT scan. Conclusion : This study suggests that operation may be justifiable in clinically poor grade patient with spontaneous intra cerebellar hemorrhage.

• Journal of Korean Neurosurgical Society
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• 제42권3호
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• pp.173-178
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• 2007

Objective : Hydrocephalus is one of the major complications following spontaneous subarachnoid hemorrhage (SAH). However, the risk factors of the hydrocephalus after SAH are not still well known. This study was focused on verification of the causal relationships between the development of hydrocephalus and SAH. Methods : The patients who developed hydrocephalus after rupture of aneurysms were studied. To obtain prognostic factors regarding to hydrocephalus, several parameters such as age, sex, hypertension, location of aneurysm, existence of intraventricular hemorrhage (IVH) and intracerebral hemorrhage (ICH), Glasgow coma scale (GCS), Hunt-Hess SAH classification & Fisher Grade on admission and the ratio of frontal harn of lateral ventricle diameter to skull inner table diameter at this level (FH/ID) were studied retrospectively. Results : The development of hydrocephalus following SAH is multifactorial. The age, IVH, FH/ID ratio were related to hydrocephalus in analysis. There is a low clinical correlation between sex, hypertension, location of aneurysm, existence of ICH, GCS, Hunt-Hess SAH classification, Fisher Grade on admission and hydrocephalus. Conclusion : Knowledge on risk factors related to the occurrence of hydrocephalus may help guide neurosurgeons in the long-term care of patients who have experienced aneurysmal SAH.

• 천문학회보
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• 제39권2호
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• pp.89-89
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• 2014

While the current consensus view holds that galaxy mergers are commonplace, it is sometimes speculated that Globular Clusters (GCs) may also have undergone merging events, possibly resulting in massive objects with a strong metallicity spread such as Omega Centauri. Galaxies are mostly far, unresolved systems whose mergers are most likely wet, resulting in observational as well as modeling difficulties, but GCs are resolved into stars that can be used as discrete dynamical tracers, and their mergers might have been dry, therefore easily simulated with an N-body code. It is however difficult to determine the observational parameters best suited to reveal a history of merging based on the positions and kinematics of GC stars, if evidence of merging is at all observable. To overcome this difficulty, we investigate the applicability of supervised and unsupervised machine learning to the automatic reconstruction of the dynamical history of a stellar system. In particular we test whether statistical clustering methods can classify simulated systems into monolithic versus merger products. We run direct N-body simulations of two identical King-model clusters undergoing a head-on collision resulting in a merged system, and other simulations of isolated King models with the same total number of particles as the merged system. After several relaxation times elapse, we extract a sample of snapshots of the sky-projected positions of particles from each simulation at different dynamical times, and we run a variety of clustering and classification algorithms to classify the snapshots into two subsets in a relevant feature space.

• 천문학회보
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• 제39권2호
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• pp.69.2-69.2
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• 2014

We present space-based near-IR (NIR) and optical photometry of globular clusters (GCs) of 16 early-type galaxies in the Fornax and Virgo Clusters. The NIR imaging data for the nearby galaxies was acquired with the IR Channel of the Wide Field Camera 3 (WFC3/IR) in the F110W ($J_{110}$) and F160W ($H_{160}$) bandpasses. We introduce the full sample of our WFC3/IR program, describe data reductions and photometric measurements including GC candidate selection criteria, and then show selected GCs' color-magnitude diagrams. The tilted features in the diagrams related to the morphological types of host galaxies are discussed in the context of galaxy formation and evolution histories. Combining F475W ($g_{475}$) and F850LP ($z_{850}$) data taken from the Advanced Camera for Surveys Virgo and Fornax Cluster Surveys with our NIR data, we investigate the bimodality in optical-NIR color distribution and the nonlinear feature of the optical-NIR color relation as a function of optical color for these extragalactic GC systems.

• 천문학회보
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• 제41권2호
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• pp.43.4-44
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• 2016

The presence of multiple stellar populations is now well established in most globular clusters (GCs) in the Milky Way. The origin of this phenomenon, however, is yet to be understood. In this respect, the study of NGC 2808, an intriguing GC which hosts subpopulations with extreme helium abundances, would help to resolve this problem. In order to investigate chemical abundance patterns among different subpopulations in this GC, we have performed low-resolution spectroscopy for the red-giant-branch (RGB) stars and measured CN & CH bands, and Ca line strength. We have identified at least three subpopulations from the CN abundance distribution. This GC shows CN-CH anti-correlation following the general trend among "normal" GCs. In addition, we have cross-matched our results with the high-resolution data in literature, and found a tight correlation between CN strength and sodium abundance. However, CN is anticorrelated with oxygen abundance, as expected from the well known N(&Na)-O anticorrelation. In this talk, we will discuss the implication of these results.

• BMB Reports
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• 제35권1호
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• pp.7-18
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• 2002

The major function of the thymus is to eliminate developing thymocytes that are potentially useless or autoreactive, and select only those that bear functional T cell antigen receptors (TCRs) through fastidious screening. It is believed that glucocorticoids (GCs) are at least in part responsible for cell death during death by neglect. In this review, we will mainly cover the topic of the GC-induced apoptosis of developing thymocytes. We will also discuss how thymocytes that are fated to die by GCs can be rescued from GC-induced apoptosis in. response to a variety of signals with antagonizing properties for GC receptor (GR) signaling. Currently, a lot of evidence supports the notion that the decision is made as a result of the integration of the multiple signal transduction networks that are triggered by GR, TCR, and Notch. A few candidate molecules at the converging point of these multiple signaling pathyways will be discussed. We will particularly describe the role of the SRG3 protein as a potent modulator of GC-induced apoptosis in the crosstalk.