• Title/Summary/Keyword: GBS

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Development and Mechanical Performance Evaluation of Lumbar Porous Interbody Fusion Cage (요추부 다공성 추간체유합보형재의 개발 및 기계적 성능 평가)

  • Ahn, Yoon-Ho;Yoo, Kyeong-Joo;Park, Kwang-Min;Cha, Eun-Jong;Kim, Kyung-Ah;Ahn, Kyoung-Gee
    • Journal of Biomedical Engineering Research
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    • v.41 no.1
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    • pp.14-21
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    • 2020
  • Recently, porous additive manufactured(AM) cages have been introduced to provide more desirable stiffness and may be beneficial to bone ingrowth. They are designed to attempt to reduce the subsidence problem of traditional titanium cage and to get osseointegrative property that PEEK doesn't have. This study was performed to evaluate the mechanical performance of newly developed lumbar porous AM cages. Three types of mechanical tests were performed in accordance with the ASTM standards: Static compression, compression-shear, and subsidence tests. The porous AM cages with 60% porosity showed similar device stiffness and strength as the various products submitted to FDA 510(k), and their wider contact area improved the subsidence test results by about 50%. In conclusion, the porous AM cages developed in this study were considered mechanically safe and could be an alternative to solid PEEK cages.

A Case of Combined Korean Medicine Treatment for Recurrent Limb Weakness after Guillain-Barré Syndrome Improvement: Case Report (길랑바레 증후군 호전 이후 재발한 사지무력 증상에 대한 한방 복합치료 1예: 증례보고)

  • Park, Song-Mi;Cho, Sung-Woo
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.4
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    • pp.135-142
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    • 2019
  • The objective of this study is to propose Korean Medicine treatment for recurrent limb weakness after Guillain-Barre syndrome (GBS) improvement by intraveinous immunoglobulin, and to report its effectiveness. Manual muscle test (MMT), Korean modified Bathel index (K-MBI), and tendon reflex were used to evaluate the patient. The patient was improved hip joint, knee joint, ankle joint MMT from grade 3-/3- to grade 5/5 and in the upper limb the patient can do big joint exercise but cannot do micromovement like writing or using cell phone. When discharge date the patient's wrist joint MMT grade is improved grade 5-/5- to grade 5/5. The K-MBI score is improved from 71 to 86 and there was a big change in walking and chair/bed transfer, there was no change in tendon reflex. This study suggests that Korean Medicine can be effective for patients who have recurrent limb weakness after GBS improvement.

Guillain-Barre Syndrome after Minimally Invasive Lumbar Procedure: A Case Report (요추부 최소침습적 시술 후 길랑-바레 증후군: 증례보고)

  • Lee, Bong-Yeon;Yoon, Seo-Ra;Ryu, Su-Ra;Choe, Yu-Ri
    • Journal of Electrodiagnosis and Neuromuscular Diseases
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    • v.20 no.2
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    • pp.159-163
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    • 2018
  • Guillain-Barre syndrome (GBS) after trauma and general orthopedic surgery is rare. A 74-year-old woman showed ascending paralysis symmetrically, dysarthria, dysphagia and areflexia on 14 days after minimally invasive endoscopic thermoannuloplasty on L4-5 level. Brain and lumbar magnetic resonance imaging demonstrate no abnormal findings. The electrodiagnostic study showed prolonged distal motor, sensory latencies and F-wave latencies and reduced amplitude of compound muscle action potential in nerves of upper and lower extremities. In the cerebrospinal fluid (CSF) examination, total protein and IgG were increased. We diagnosed Guillain-Barre Syndrome based on clinical features, electrodiagnostic study and CSF examination and the patient improved symptoms after immunoglobulin injection and rehabilitation. Because the occurrence of GBS after minimally invasive procedure has not been reported, we report a case of GBS after minimally invasive procedure with literature review.

A Study on Pullout Characteristics of Pedicle Screw Design Considering Anatomical Structure of the Lumbar Spine (척추의 해부학적 요소를 고려한 척추경 나사못 디자인의 Pullout 특성 연구)

  • Yoo, Kyeong-Joo;Park, Kwang-Min;Ahn, Kyoung-Gee;Ahn, Yoon-Ho
    • Journal of Biomedical Engineering Research
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    • v.42 no.1
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    • pp.1-6
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    • 2021
  • Recently, various types of pedicle screws have been developed considering the anatomical structure of the spine. The purpose of this study was to evaluate the pullout stiffness and strength of two types of commercial pedicle screws. The design of two type screws were single pitched thread (ST) pedicle screw and dual pitched thread (DT) pedicle screw, respectively. The tests were conducted in accordance with the ASTM standards using polyurethane (PU) test blocks which has anatomical structure of the spine. There was no significant difference in pullout stiffness between two types of screw. However, DT exhibited higher pullout strength than ST (p<0.05). Pedicle screw with dual pitched thread showed higher pullout strength without decrease in pullout stiffness compared to the standard pedicle screw. In conclusion, dual pitched thread design of the pedicle screw is considered to be more suitable than the single pitched thread for the anatomical structure of the spine.

Interoperability Analysis for BIM software Based on User-defined Properties (BIM 소프트웨어 호환성 분석 : 사용자정의 속성정보인 GBS를 중심으로)

  • Kang, Seunghee;Ha, Jiwon;Ju, Taehwan;Jung, Youngsoo
    • Korean Journal of Construction Engineering and Management
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    • v.17 no.2
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    • pp.99-109
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    • 2016
  • The utilization of Building Information Modeling (BIM) has increased in order to enhance the integration of information for management and resources throughout the construction projects. Therefore, various BIM softwares have been used under open BIM environments in the building and plant construction industry. However, it has obstructive factors due to the lack of interoperability. In order to address this problem, this study conducted an interoperability analysis of BIM software focused on user-defined properties for enhanced function and efficiency. Result of the analysis shows that authoring tools have more interoperability problems than viewer tools and simulation tools have. In terms of interoperability, user-defined properties outperforms than those of system basic properties and logic data. Therefore, it was found that functional improvement and workload minimization in BIM can be attained by applying the GBS (an user-defined property for automatic manipulation of BIM proposed by Jung et al. 2013) that enables automatic link between geometric data and non-geometric data. In this respect, this study concludes that the application of user-defined property (e.g. GBS) can be an effective method for information integration throughout construction projects.

A Study on Residual Strength Assessment of Damaged Oil Tanker by Smith Method (Smith법에 의한 손상 유조선의 잔류강도 평가 연구)

  • Ahn, Hyung-Joon;Baek, Deok-Pyo;Lee, Tak-Kee
    • Journal of Navigation and Port Research
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    • v.35 no.10
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    • pp.823-827
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    • 2011
  • The present Common Structural Rules for double hull oil tanker is not included the residual strength, which is one of the functional requirements in design part of Goal-based new ship construction standards (GBS). The GBS will be enforced after July 1, 2016. The requirement related residual strength has the goal to build safe ship even if she has the specified damages due to marine accidents including collision and grounding. In order to assess the residual strength based on risk for structural damages according to GBS, tons of nonlinear FE analysis work taking into account various types of damage will be needed. The Smith's method, a kind of simplified method for the strength analysis is very useful for this purpose. In this paper, the residual strength assessments based on ultimate strength using Smith's method were carried out. The objected ship is VLCC with stranding damage in bottom structures. Also, the results were compared with that of nonlinear FE analysis using three cargo hold model.

Development of an SNP set for marker-assisted breeding based on the genotyping-by-sequencing of elite inbred lines in watermelon (수박 엘리트 계통의 GBS를 통한 마커이용 육종용 SNP 마커 개발)

  • Lee, Junewoo;Son, Beunggu;Choi, Youngwhan;Kang, Jumsoon;Lee, Youngjae;Je, Byoung Il;Park, Younghoon
    • Journal of Plant Biotechnology
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    • v.45 no.3
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    • pp.242-249
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    • 2018
  • This study was conducted to develop an SNP set that can be useful for marker-assisted breeding (MAB) in watermelon (Citrullus. lanatus L) using Genotyping-by-sequencing (GBS) analysis of 20 commercial elite watermelon inbreds. The result of GBS showed that 77% of approximately 1.1 billion raw reads were mapped on the watermelon genome with an average mapping region of about 4,000 Kb, which indicated genome coverage of 2.3%. After the filtering process, a total of 2,670 SNPs with an average depth of 31.57 and the PIC (Polymorphic Information Content) value of 0.1~0.38 for 20 elite inbreds were obtained. Among those SNPs, 55 SNPs (5 SNPs per chromosome that are equally distributed on each chromosome) were selected. For the understanding genetic relationship of 20 elite inbreds, PCA (Principal Component Analysis) was carried out with 55 SNPs, which resulted in the classification of inbreds into 4 groups based on PC1 (52%) and PC2 (11%), thus causing differentiation between the inbreds. A similar classification pattern for PCA was observed from hierarchical clustering analysis. The SNP set developed in this study has the potential for application to cultivar identification, F1 seed purity test, and marker-assisted backcross (MABC) not only for 20 elite inbreds but also for diverse resources for watermelon breeding.

SLA 기반 GBS

  • Lee, Jong-Gap
    • Bulletin of the Society of Naval Architects of Korea
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    • v.44 no.1
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    • pp.94-98
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    • 2007
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DEGREE OF APPROXIMATION FOR BIVARIATE SZASZ-KANTOROVICH TYPE BASED ON BRENKE TYPE POLYNOMIALS

  • Begen, Selin;Ilarslan, H. Gul Ince
    • Honam Mathematical Journal
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    • v.42 no.2
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    • pp.251-268
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    • 2020
  • In this paper, we estimate the degree of approximation by means of the complete modulus of continuity, the partial modulus of continuity, the Lipschitz-type class and Petree's K-functional for the bivariate Szász-Kantorovich operators based on Brenke-type polynomials. Later, we construct Generalized Boolean Sum operators associated with combinations of the Szász-Kantorovich operators based on Brenke-type polynomials. In addition, we obtain the rate of convergence for the GBS operators with the help of the mixed modulus of continuity and the Lipschitz class of the Bögel continuous functions.