• Title/Summary/Keyword: GBS

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Bickerstaff's Brainstem Encephalitis with Guillain-Barr$\acute{e}$ Syndrome Presenting Severe Paralytic Ileus (길랑-바레증후군이 동반된 Bickerstaff 뇌줄기뇌염에서 나타난 심한 마비성 장 폐색)

  • Park, Min-Su
    • Annals of Clinical Neurophysiology
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    • v.11 no.1
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    • pp.33-36
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    • 2009
  • Bickerstaff's brainstem encephalitis (BBE) is an autoimmune central nervous system disorder. It can occur in more limited forms and may overlap with Guillain-Barr$\acute{e}$ syndrome (GBS). A 49-year-old female presented with rapidly progressive paralytic ileus, urinary retention, deep drowsiness, ophthalmoplegia, dysarthria, ataxia, quadriparesis and hyporeflexia after viral meningitis. She was diagnosed as BBE with GBS and treated with immunoglobulin. She was completely recovered after 1 month. It is a rare case of BBE overlapping with GBS presenting with severe paralytic ileus.

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A Case of Acute Motor Axonal Guillain-Barré Syndrome combined with Acute Cervical-Upper Thoracic Transverse Myelitis (급성 운동축삭성 길랑-바레 증후군과 동반된 급성 경수-상흉수 횡단성 척수염 1예)

  • Lee, Dong-Kuck
    • Annals of Clinical Neurophysiology
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    • v.3 no.2
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    • pp.172-175
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    • 2001
  • Guillain-$Barr{\acute{e}}$ syndrome(GBS) is a common demyelinating disease of the peripheral nervous system. But recently, the axonal types are also reported. Acute transverse myelitis(ATM) is also a common inflammatory disease of the spinal cord. Generally, it is difficult to identify the etiology of GBS and ATM. I guess the occurrence of the 2 diseases at once is hard to take the place. A 63-year-old woman showed an acute motor axonal GBS and a cervical-upper thoracic ATM occurring at the same time. She was treated by intravenous immunoglobulin and solumedrol therapy. Her sensory symptoms were improved rapidly but motor symptoms showed only mild improvement.

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Point defects and grain boundary effects on tensile strength of 3C-SiC studied by molecular dynamics simulations

  • Li, Yingying;Li, Yan;Xiao, Wei
    • Nuclear Engineering and Technology
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    • v.51 no.3
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    • pp.769-775
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    • 2019
  • The tensile strength of irradiated 3C-SiC, SiC with artificial point defects, SiC with symmetric tilt grain boundaries (GBs), irradiated SiC with GBs are investigated using molecular dynamics simulations at 300 K. For an irradiated SiC sample, the tensile strength decreases with the increase of irradiation dose. The Young's modulus decreases with the increase of irradiation dose which agrees well with experiment and simulation data. For artificial point defects, the designed point defects dramatically decrease the tensile strength of SiC at low concentration. Among the point defects studied in this work, the vacancies drop the strength the most seriously. SiC symmetric tilt GBs decrease the tensile strength of pure SiC. Under irradiated condition, the tensile strengths of all SiC samples with grain boundaries decrease and converge to certain value because the structures become amorphous and the grain boundaries disappear after high dose irradiation.

Acute combined central and peripheral nervous system demyelination: a case report

  • Roh, Young Eun;Kim, Young Mi
    • Kosin Medical Journal
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    • v.33 no.2
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    • pp.257-262
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    • 2018
  • Guillain-$Barr{\acute{e}}$ syndrome (GBS) and acute disseminated encephalomyelitis (ADEM) are demyelinating neurologic disorders with different target organs. Although they share similar pathogenetic mechanism, reports of simultaneous occurrence of the 2 disorders are rare. A 2 year 6 month old girl visited our hospital for fever, cough, and general weakness. Although the muscle power of extremities showed mild weakness and voiding difficulty, initial deep tendon reflex of both knees and ankles was normal. A nerve conduction study to evaluate the weakness revealed the absence of F waves. Cerebrospinal fluid analysis demonstrated pleocytosis with lymphocyte predominance and elevated protein levels. Magnetic resonance imaging showed abnormal T2 hyperintensity in pons, medulla and spinal cord. Serum anti-GD1b antibody was positive. Based on clinical findings, laboratory findings, nerve conduction study, and neuroimaging, the diagnosis of GBS and ADEM was made. This is the first case of GBS accompanied by ADEM in Korea.

Guillain-Barré syndrome supervening on meningitis in primary Epstein-Barr virus infection

  • Lee, Jeong-Yoon;Sunwoo, Jun-Sang;Kwon, Kyum-Yil;Lee, Kyung Bok;Ahn, Moo-Young;Roh, Hakjae
    • Annals of Clinical Neurophysiology
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    • v.21 no.1
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    • pp.48-52
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    • 2019
  • Primary Epstein-Barr virus (EBV) infection can manifest with a broad spectrum of neurological complications. There are only rare reports of Guillain-$Barr{\acute{e}}$ syndrome (GBS) supervening on meningitis in patients with primary EBV infection. Clear evidence of central nervous system infection makes it difficult for the clinicians to consider a diagnosis of GBS. We present a patient with GBS supervening on meningitis in primary EBV infection.

Molecular Serotyping of Group B Streptococcus Isolated from the Pregnant Women by Polymerase Chain Reaction and Sequence Analysis (임신부에서 분리된 B군 연구균의 중합효소연쇄반응과 염기서열분석을 통한 혈청형 분석)

  • Oh, Chi Eun;Jang, Hyun Oh;Kim, Nam Hee;Lee, Jina;Choi, Eun Hwa;Lee, Hoan Jong
    • Pediatric Infection and Vaccine
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    • v.16 no.1
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    • pp.47-53
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    • 2009
  • Purpose : This study was performed to investigate the serotype distribution of group B streptococcus (GBS) isolated from pregnant Korean women using molecular methods. Methods : The study materials included 42 GBS isolates obtained from the vagina and anorectum of pregnant women in Goyang, Korea between 2005 and 2006. Four clinical isolates with known serotypes (Ia, Ib, III, and V) were used for validation of molecular serotyping. We used serotype-specific primers for identification of the serotypes (Ia, Ib, III, V, and VI). To determine the ambiguous serotypes by serotype-specific PCR, sequence analysis of the PCR amplicons which had been amplified with GBS-common primers was used. Results : The serotypes determined by the molecular methods agreed with the previously known 4 serotypes (Ia, Ib, III, and V). The serotypes of all 42 isolates were successfully determined by molecular methods. The distribution of the GBS serotype was as follows in order of frequency: serotype III was found in 12 isolates (28.6%), serotype V was found in 11 isolates (26.2%), serotype Ia was found in 11 isolates (26.2%), serotype VI was found in 4 isolates (9.5%), serotype Ib was found in 2 isolates (4.8%), and serotype II was found in 2 isolates (4.8%). Conclusion : Serotypes III, V, and Ia were the most frequently identified serotypes in pregnant Korean women. Molecular serotyping is useful for surveillance of the serotype distribution of GBS in colonized pregnant women and GBS diseases of neonates.

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A Study on the Improvement of Properties of High Strength Concrete Using Mineral Admixtures (광물질 혼화재 혼합 고강도콘크리트의 제성질 개선에 대한 연구)

  • 문한영;문대중;하상욱
    • Proceedings of the Korea Concrete Institute Conference
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    • 1997.04a
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    • pp.335-340
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    • 1997
  • The mineral admixtures, ground granulated blast furnace slag (GSB) and fly ash (FA), were mixed with ordinary portland cement(OPC) in order to reduce temperature rise and slump loss in concrete. In according to concrete replaced with 30% of GBS, the compressive strength of that developed to 574 kg/$\textrm{cm}^2$ at age of 28days and maximum temperature decreased to the extent of $5^{\cire}C$. When GBS and FA are mixed with concrete, it can be estimated that mix proportions of them have to be taken into consideration.

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Development of the Instructional Design Guideline utilizing Goal-based Scenario for Culinary Practice Education

  • Ko, Beom-Seok;Na, Tae-Kyun
    • Culinary science and hospitality research
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    • v.22 no.1
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    • pp.141-152
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    • 2016
  • Recently, not only development of curriculum associated directly with job, the development of new education model is in great need. So, the purpose of this study is to develop the instructional design guideline utilizing goal-based scenario(GBS) for college students who major in culinary arts. First, to achieve this goal, we recognized the 7 core elements(learning goal, mission, cover story, role activity, scenario operating, resource, feedback) composing GBS through literature review and case study. Second, we drew a conclusion about the problem and guideline for traditional culinary practice course by conducting inspection about culinary practice environment and needs with professors who are teaching culinary arts. Third, we applied the instructional design guideline for culinary practice to regular classes according to GBS's factors, and then we did formative evaluation with content experts and educational technology expert. Finally, we designed the final instructional design guideline for culinary practice by modifying early model reflected the result of formative evaluation. The results of this study are as following. First, when we applied GBS to culinary practice, professors have to focus on process of materialization by developing easy scenario to students. Also, they have to prepare the class circumstance to feel about sense of realism in advance. Second, to give a conjugally new skill at working, professors's effort is important. culinary practice education at college has responsibility to carry out the vocational training that has competitiveness and difference with labor market's needs. Therefore, it is necessary for us to develop the teaching and learning model for culinary practice which is suitable for major based on the manpower demand for industry without causing job mismatch from demand for industry.

Application of Social Network Analysis on Learner Interaction in a GBS Learning Environment (GBS 학습 환경 하에서 상호작용 연구를 위한 사회 연결망 분석 기법의 적용)

  • Jo, Il-Hyun
    • The Journal of Korean Association of Computer Education
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    • v.6 no.2
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    • pp.81-93
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    • 2003
  • The purpose of the study was to explore the potential of the Social Network Analysis as an analytical tool for scientific investigation of learner-learner, or learner-tutor interaction within an e-Learning environment. Theoretical and methodological implication of the Social Network Analysis had been discussed. Following theoretical analysis, an exploratory empirical study was conducted to test statistical correlation between traditional performance measures such as achievement and team contribution index, and the centrality measure, one of the many quantitative measures the Social Network Analysis provides. Results indicate the centrality measure was correlated with the higher order learning performance and peer-evaluated contribution indices. An interpretation of the results and their implication to instructional design theory and practices were provided along with some suggestions for future research.

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Radiation damage in helium ion-irradiated reduced activation ferritic/martensitic steel

  • Xia, L.D.;Liu, W.B.;Liu, H.P.;Zhang, J.H.;Chen, H.;Yang, Z.G.;Zhang, C.
    • Nuclear Engineering and Technology
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    • v.50 no.1
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    • pp.132-139
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    • 2018
  • Nanocrystalline reduced activation ferritic/martensitic (RAFM) steel samples were prepared using surface mechanical attrition treatment (SMAT). Un-SMATed and SMATed reduced activation ferritic/martensitic samples were irradiated by helium ions at $200^{\circ}C$ and $350^{\circ}C$ with 2 dpa and 8 dpa, respectively, to investigate the effects of grain boundaries (GBs) and temperature on the formation of He bubbles during irradiation. Experimental results show that He bubbles are preferentially trapped at GBs in all the irradiated samples. Bubble denuded zones are clearly observed near the GBs at $350^{\circ}C$, whereas the bubble denuded zones are not obvious in the samples irradiated at $200^{\circ}C$. The average bubble size increases and the bubble density decreases with an increasing irradiation temperature from $200^{\circ}C$ to $350^{\circ}C$. Both the average size and density of the bubbles increase with an increasing irradiation dose from 2 dpa to 8 dpa. Bubbles with smaller size and lower density were observed in the SMATed samples but not in the un-SMATed samples irradiated in the same conditions, which indicate that GBs play an important role during irradiation, and sink strength increases as grain size decreases.