• Electronics and Telecommunications Trends
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• v.30 no.1
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• pp.42-50
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• 2015

PON(Passive Optical Network)은 설치 및 유지보수가 편리하여 광가입자망으로 널리 사용되고 있다. 대표적인 PON 기술로 IEEE에서 표준화된 EPON(Ethernet PON), 10G EPON과 ITU-T에서 표준화된 GPON(Gigabit capable PON), XG-PON 기술이 있다. EPON 및 GPON은 각각 1G급 및 2.5G급 전송속도를 제공하며 한국, 일본, 중국 등 아시아와 북미 등에서 가입자 서비스 및 비즈니스 서비스용으로 사용되고 있다. 2010년대부터 10G급 PON 기술 사용이 증가되고 있으며, 앞으로 가파르게 증가하고 있는 가입자 트래픽량에 대처하기 위해 40G급 또는 100G급 PON 기술이 사용될 것으로 예상된다. 본고에서는 현재 ITU-T에서 표준화가 진행 중인 NG-PON2(Next Generation PON2) 기술 중 주요기술인 TWDM-PON(Time and Wavelength Division Multiplexing-PON) 기술에 대한 국제 표준화 현황 및 국내외 기술개발 현황을 살펴보고자 한다.

• Journal of the Korea Institute of Military Science and Technology
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• v.3 no.1
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• pp.164-175
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• 2000

Three compounds of Cu(II)-loaded N,N,N'-trimethylethylenediaminated Merrifield-type polymers were synthesized with yields higher than 80%, and the hydrolysis reaction rates of O-isopropylmethyl-phosphonofluoridate(GB) and O-pinacolylmethylphosphonofluoridate (GD) catalyzed by them have been surveyed. GB and GD hydrolysis by Cu(II)-loaded polymers occurs via intermediate complex mechanism where rapid equilibrium to form intermediate complex between substrate and Cu(II)-loaded polymers($K_f$) is followed by rate determining hydrolysis step($k_1$). The measured activation parameters for $k_1$ are ${\Delta}H^{\ddag}$ : $17.75{\pm}0.98kJ/mol$ ${\Delta}S^{\ddag}$ / : $-218.42{\pm}3.35J/mol$ K, $E^{\circ}_a$ : $20.22{\pm}0.98kJ/mo1$ for GB and ${\Delta}H^{\ddag}$ / : $11.16{\pm}1.15kJ/mol,$${\Delta}S^{\ddag}$ /: $-258.57{\pm}3.93J/mol$ K, $E^{\circ}_a$ : $13.64{\pm}1.15 kJ/mol$ for GD. Standard enthalpy/entropy changes corresponding to the intermediate complex formation constant $K_f$ are ${\Delta}H^{\circ}$ : $37.05{\pm}2.19 kJ/mo1,$$ {\Delta}S^{\circ}$ : $163.12{\pm}7.49 J/mol$ K and ${\Delta}H^{\circ}$ : 418.59{\pm}2.04 kJ/mol,$ ${\Delta}S^{\circ}$ : 4111.92{\pm}6.98 J/mol$ K for GB and GD, respectively, The electron push-pull mechanism by Cu(II)-loaded polymers lowers the P-F bond breaking energy(~400 kJ/mol) to less than 1/20 compared to the case in which no Cu(II)-loaded resin presents. Analysis of $K_f$ and 4k_1$ over pH=6.5~8.0 range suggest that the GB and GD hydrolysis occurs intramolecularily with $pK_a$ =7.29 for ligated $H_2O$ and $t_{1/2}$=36.9 sec, $pK_a$ = 7.06 and $t_{1/2}$=177.7 sec for GB and GD, respectively.

• Advanced Industrial SCIence
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• v.1 no.1
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• pp.7-15
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• 2022

To adopt the development in the medical scenario IoT developed towards the advancement with the processing of a large amount of medical data defined as an Internet of Medical Things (IoMT). The vast range of collected medical data is stored in the cloud in the structured manner to process the collected healthcare data. However, it is difficult to handle the huge volume of the healthcare data so it is necessary to develop an appropriate scheme for the healthcare structured data. In this paper, a machine learning mode for processing the structured heath care data collected from the IoMT is suggested. To process the vast range of healthcare data, this paper proposed an MTGPLSTM model for the processing of the medical data. The proposed model integrates the linear regression model for the processing of healthcare information. With the developed model outlier model is implemented based on the FinTech model for the evaluation and prediction of the COVID-19 healthcare dataset collected from the IoMT. The proposed MTGPLSTM model comprises of the regression model to predict and evaluate the planning scheme for the prevention of the infection spreading. The developed model performance is evaluated based on the consideration of the different classifiers such as LR, SVR, RFR, LSTM and the proposed MTGPLSTM model and the different size of data as 1GB, 2GB and 3GB is mainly concerned. The comparative analysis expressed that the proposed MTGPLSTM model achieves ~4% reduced MAPE and RMSE value for the worldwide data; in case of china minimal MAPE value of 0.97 is achieved which is ~ 6% minimal than the existing classifier leads.

• Journal of the korean academy of Pediatric Dentistry
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• v.36 no.3
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• pp.348-357
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• 2009

The purpose of this study was to evaluate the micro-tensile bond strength (${\mu}TBS$) of four luting resin to regional dentin of human primary teeth. Dentin from non-carious primary molars were prepared from different regions (s, superficial dentin; d, deep dentin; c, cervical dentin), and divided into groups based on anatomical locations and types of luting resins (Scotchbond Multi-purpose : SB ; One-Step : OS ; AdheSE Bond : ASE ; G-Bond : GB) : SB-s, SB-d, SB-c; OS-s, OS-d, OS-c; ASE-s, ASE-d, ASE-c ; GB-s, GB-d, GB-c. Luting resins were used according to the manufacturers' instructions, to bond $Light-Core^{TM}$ Core Build-Up Composite) to the exposed dentin specimens in the light-curing mode. After storage for 1 day, ${\mu}TBS$ was tested at a cross-head speed of 1 mm/min. Data were analyzed with T-test and two-way ANOVA. The bonding interface and fractography analyses were performed with SEM. The results were as follows : 1. ${\mu}TBS$ to superficial dentin was significantly higher than to deep dentin for SB(p<0.05). But there were no significant differences in regional ${\mu}TBS$ among OS, ASE, GB(p>0.05). 2. There were no significant differences in ${\mu}TBS$ to superficial dentin among each groups. But, in deep dentin, ${\mu}TBS$ of SB-d was significantly lower than those of OS-d, ASE-d, and GB-d(p<0.05). ${\mu}TBS$ of OS-d was significantly higher than those of GB-d(p<0.05), but there were no significant differences in ${\mu}TBS$ of ASEd. There were no significant differences among ${\mu}TBS$ of ASE-d, OS-d, and GB-d.

• Applied Microscopy
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• v.37 no.4
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• pp.239-248
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• 2007

Alteration of temperature is one of cancer therapies. In general, severe hyperthermia(around $43^{\circ}C$) and hypothermia(around $18^{\circ}C$) trigger apoptosis through mitochondria, though the specific mechanism is still unknown. CC-t6 and GB-d1 cell lines, which were originally derived from human cholangiocarcinoma and gall bladder cancer, were established from a metastatic lymph node. To investigate the mechanism of metastatic cancer cell response to thermal stresses, hyperthermia($37^{\circ}C{\rightarrow}43^{\circ}C$) and hypothermia($37^{\circ}C{\rightarrow}17.4^{\circ}C$) were designed. Thermal stresses did not induce apoptosis but necrotic cell death. Any alterations of caspase-3, -9, cytochrome c, Bax, and Bcl-2 were not found in both hyperthermia and hypothermia exposed fells using western blot analysis. In the transmission electron microscopy, typical necrotic, but not apoptotic, changes were observed. These results suggest that temperature changes induce cell death through necrotic pathway in metastatic cancer in vitro, and it can be one of effective anticancer methods.

• Korean Journal of Materials Research
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• v.33 no.6
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• pp.251-256
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• 2023

This study aims to examine the correlation between microstructures and the mechanical properties of two high-strength API X70 linepipe steels with different specimen directions and Moaddition. The microstructure of the Mo-added steel has an irregularly shaped AF, GB matrix with pearlite because of the relatively large deformation in the non-recrystallization temperature region, while that of the Mo-free steel shows a PF matrix with bainitic microstructure. In the Mo-added steel, the M/A (martensite-austenite) in granular bainite (GB) and pearlite act as crack initiation sites with decreased upper shelf energy and an increased ductile to brittle transition temperature (DBTT). Regardless of Mo addition, all of the steels demonstrate higher strength and lower elongation in the T direction than in the L direction because of the short dislocation glide path and ease of pile-up at grain boundaries. In addition, the impact test specimens with T-L direction had a lower impact absorbed energy and higher DBTT than those with the L-T direction because the former exhibit shorter unit crack path compared to the latter.

• Journal of Veterinary Clinics
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• v.24 no.2
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• pp.225-228
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• 2007

The therapy by injection-acupuncture (AP) with bee-venom (apitoxin) and injection-AP with apitoxin combined by administration of Chinese herbal medicine was applied in 2 cases with canine intervertebral disc disease (IVDD). Case 1 was diagnosed as thoraco-lumbar IVDD (T11-T12, T12-T13, L3-L4 and L4-L5) and case 2 was diagnosed as IVDD at T10-T11 and T12-T13, respectively Injection-AP with apitoxin($Apitoxinc{(R)}$, total $200{\mu}g$ of apitoxin, 0.1 ml/acupoint) plus physical exercise (walking with gocart, TID/day) and aquatherapy (swimming treatment, BID/week) were given to each patient. The used acupoints were GV20 (Bai Hui), GB30 (Huan Tiao), ST36 (Zu San Li), GB34 (Yang Ling Quan), ST40 (Feng Long), ST41 (Jie Xi) and BL40 (Wei Zhong), the lesions, and trigger points. In addition, Chinese herbal medicine (Koda Pharmaceutical Co., Taiwan) including Zheng Gu Zi Jin Dan (正骨紫金丹 : 1 g), Shiuh Duann(續斷 : 0.2 g), Du Zhong(杜仲 : 0.2 g), Mo Yao(沒藥 : 0.2 g), Ru Xian(乳香 : 0.2 g) and Pyrite(自然銅 : 0.2 g) were orallly mdeicated BID for 0\9days in case 2. Walking was possible after session 11 for 4 weeks in case 1 and after session 6 for 2 weeks in case 2, respectively.

• Journal of mucopolysaccharidosis and rare diseases
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• v.4 no.1
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• pp.21-25
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• 2018

Fabry disease is a hereditary lysosomal storage disorder caused by the reduction or absence of lysosomal enzyme alpha-galactosidase A and the accumulation of glycosphingolipids, such as globotriaosylceramide (Gb3), in various organs, including the heart. The prevention of cardiac involvement in Fabry disease can only be achieved by enzyme replacement therapy (ERT), and the method of assessing the efficacy of ERT should be confirmed. Changes in the electrocardiogram, such as the shortening of PQ interval, prolongation of QTc and repolarization abnormalities as well as left ventricular hypertrophy in voltage criteria, can be used to identify Fabry disease patients; however, the usefulness of electrocardiograms for evaluating the efficacy of ERT is limited. The assessment of left ventricular hypertrophy using echocardiography has been established to evaluate the efficacy of ERT during long-term period. A new technique involving speckled tracking method might be useful for detecting early cardiac dysfunction and identifying the effect of ERT for a relatively short period. The estimation of left ventricular hypertrophy using cardiac magnetic resonance (CMR) is also useful for assessing the efficacy of ERT. Identifying late gadolinium enhancement in CMR may affect the effectiveness of ERT, and the new technique of T1 mapping might be useful for monitoring the accumulation of Gb3 during ERT. Histopathology in cardiac biopsy specimens is another potentially useful method for identifying the accumulation of GB3; however, the use of histopathology to evaluate of the efficacy of ERT is limited because of the invasive nature of an endomyocardial biopsy.

• Journal of Plant Biotechnology
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• v.49 no.4
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• pp.316-324
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• 2022

Hair loss causes psychological stress due to its effect on appearance. Therefore, the global market for hair loss treatment products is rapidly growing. The present study demonstrated that ginseng berry-derived and sequence-modified peptides promoted the proliferation rate of dermal papilla (DP) cells and keratinocytes, in addition to having antioxidant properties. Moreover, the potential role of these ginseng berry peptides as TGF-β2 antagonists was confirmed through in silico computer docking. In addition to promoting the growth of ,the ginseng berry-derived peptides also promoted the proliferation of keratinocytes experimental Particularly, an unmodified ginseng berry-derived peptide (GB-1) and two peptides with sequence modifications (GB-2 and GB-3) decreased ROS generation and exhibited a protective effect on damaged HaCaT keratinocytes. Computer-aided peptide discovery was conducted to identify the potential interactions of important proteins with transforming growth factor-beta 2 (TGF-β2), a key protein that plays a crucial role in the human hair growth cycle. Our results demonstrated that MAGH, an amino acid sequence present in herbal supplements and plant-based natural compounds, can inhibit TGF-β2.

• Journal of Fashion Business
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• v.6 no.6
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• pp.78-88
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• 2002

The purpose of this study is to provide for some basic data useful to production of the apparels fit and measured well for the Chinese men. For this purpose, 389 men aged between 20 and 49 and living in Beijing and Shanghai, China were sampled to be measured for their constitutions. Then, their constitutions were classified and thereupon, according to the Men's Wear Specifications (GB/T 1335.1-1997), National Standards of People's Republic of China. The collected data were statistically processed using SAS 6.12 for technical statistical analysis, correlation analysis, factor analysis, group-wise analysis. The results of this study can be summarized as follows; 1. As a result of the factor analysis aiming to determine Chinese men's constitutional components, five components could be identified: constitutional obesity, lateral body size, longitudinal body size, shoulder and back width, and shoulder drooping. 2. As a result of classifying Chinese men's constitutions according to drop measurements, four types could be identified. Y type had the lowest obesity and the highest longitudinal body size. A type had a lower obesity and had an average longitudinal body size. B Type had the second highest obesity, the smallest longitudinal body size and shoulders/back width. C Type had the highest obesity, upper body length and shoulders/back width. 3. In terms of distribution, 'B' type (39.10%) of the sample, followed by 'A' type (29.26%), 'C' type (19.95%) and 'Y' type (11.70%). In all, the results of this study suggests that 'B' type represents the Chinese men in contrast with GB specifying that 'A' type represents the Chinese men. On the other hand, Beijing region was dominated most by 'B' type (37.06%), followed by 'A' type (28.82%), 'C' type (22.35%) and 'Y' type (11.76%), while Shanghai region was dominated most by 'B' type (41.13%), followed by 'A' type (31.21%), 'C' type (19.15%) and 'Y' type (8.51%).