• 제목/요약/키워드: GAP43

검색결과 443건 처리시간 0.027초

The Study on Regenerative Effects of Ginseng on Injured Axonal and Non-Neuronal cell

  • Lim, Chang-Bum;Oh, Min-Seok
    • 대한한의학회지
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    • 제29권5호
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    • pp.14-28
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    • 2008
  • Objective : This study was carried out to understand effects of ginseng(hearinafter ; GS, Panax Ginseng) extract on regeneration responses on injured sciatic nerves in rats. Methods :Using white mouse, we damaged sciatic nerve & central nerve, and then applied GS to the lesion. Then we observed regeneration of axon and non-neuron. Results : 1. NF-200 protein immunostaining for the visualization of axons showed more distal elongation of sciatic nerve axons in GS-treated group than saline-treated control 3 and 7 days after crush injury. 2. GAP-43 protein was increased in the injured sciatic nerve and further increased by GS treatment. Enhanced GAP-43 protein signals were also observed in DRG prepared from the rats given nerve injury and GS treatment. 3. GS treatment in vivo induced enhanced neurite outgrowth in preconditioned DRG sensory neurons. In vitro treatment of GS on sensory neurons from intact DRG also caused increased neurite outgrowth. 4. Phospho-Erk1/2 protein levels were higher in the injured nerve treated with GS than saline. Phospho-Erk1/2 protein signals were mostly found in the axons in the injured nerve. 5. NGF and Cdc2 protein levels showed slight increases in the injured nerves of GS-treated group compared to saline-treated group. 6. The number of Schwann cell population was significantly increased by GS treatment in the injured sciatic nerve. GS treatment with cultured Schwann cells increased proliferation and Cdc2 protein signals. 7. GS pretreatment into the injured spinal cord generated increased astrocyte proliferation and oligodendrocytes in culture. In vitro treatment of GS resulted in more differentiated pericytoplasmic processes compared with saline treatment. 8. More arborization around the injury cavity and the occurrence at the caudal region of CST axons were observed in GS-treated group than in saline-treated group. Conclusion :GS extract may have the growth-promoting activity on regenerating axons in both peripheral and central nervous systems.

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다중 큐 SSD 기반 I/O 가상화 프레임워크의 성능 향상 기법 (Improving Performance of I/O Virtualization Framework based on Multi-queue SSD)

  • 김태용;강동현;엄영익
    • 정보과학회 논문지
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    • 제43권1호
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    • pp.27-33
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    • 2016
  • 오늘날 가상화 기술은 가장 유용하게 사용되는 컴퓨팅 기술 중 하나이며 모든 컴퓨팅 환경에서 널리 활용되고 있다. 그러나 가상화 환경의 I/O 계층들은 호스트 머신의 I/O 동작 방식을 인지하지 못하도록 설계되어 있기 때문에 I/O 확장성 문제는 여전히 해결해야 할 문제로 남아 있다. 특히, 다중 큐 SSD가 보조 기억 장치로 사용될 경우, 증가한 잠금 경쟁과 제한된 I/O 병렬화 문제로 가상 머신은 다중 큐 SSD의 공인된 성능을 활용하지 못하는 문제가 발생한다. 이러한 성능 문제를 해결하기 위해 본 논문에서는 가상 CPU마다 전용 큐와 I/O 스레드를 할당하는 새로운 기법을 제안한다. 제안 기법은 성능 저하의 주요한 원인 중 하나인 잠금 경쟁을 효율적으로 분산시키고 또 다른 원인인 Virtio-blk-data-plane의 병렬화 문제를 해소한다. 제안 기법을 평가한 결과 최신 QEMU 보다 IOPS가 최대 155% 향상되는 것을 확인하였다.

대전시 3대 하천의 수질 및 식물플랑크톤상에 관한 연구 (The study on water quality and phytoplankton flora at 3 rivers in the Taejon city)

  • 강창민;이상명;엄준식;이정희;이호원;홍춘표
    • 한국환경과학회지
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    • 제9권4호
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    • pp.275-284
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    • 2000
  • The studyies on physico-chemical factors and phytoplankton at the 3 rivers in the Taejon city were conducted from November 1997 to May 1998. The Results were as floows; In the water quality, the down streams were generally worse than the upper streams. Water temperature was varied from 2.4$^{\circ}C$ to 23.$0^{\circ}C$; DO from 1.80mg/$\ell$ to 17.6mg/$\ell$ ; pH from 4.7 to 10.4 ; BOD from 0.78mg/$\ell$ to 8.80mg/$\ell$ ; COD from 0.32mg/$\ell$ to 8.26mg/$\ell$ ; SS from 2.0mg/$\ell$ to 43.0mg/$\ell$ ; total phosphate was from 0.001mg/$\ell$ to 0.709mg/$\ell$ ; total nitrogen 0.01mg/$\ell$ to 11.69mg/$\ell$. In phytoplankton species, they were identified as total 191 taxa composed of 8 classes, 18 orders, 35 families, 74 genera, 152 species, 35 varieties and 4 forms. The dominant species were Synedra ulna in Taejon-chon, Diatomavulgare in Yudong-chon, Oscillatioria princeps, Scenedesmus qadricauda, Synedra ulna, and Diatom vulgare in Gap-chon. Standing crops of phytoplankton were from 2,076 cells/$m\ell$ to 97,356 cells/$m\ell$

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Characterization of Pseudomonas syringae pv. syringae, Causal Agent of Citrus Blast of Mandarin in Montenegro

  • Ivanovic, Zarko;Perovic, Tatjana;Popovic, Tatjana;Blagojevic, Jovana;Trkulja, Nenad;Hrncic, Snjezana
    • The Plant Pathology Journal
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    • 제33권1호
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    • pp.21-33
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    • 2017
  • Citrus blast caused by bacterium Pseudomonas syringae is a very important disease of citrus occuring in many areas of the world, but with few data about genetic structure of the pathogen involved. Considering the above fact, this study reports genetic characterization of 43 P. syringae isolates obtained from plant tissue displaying citrus blast symptoms on mandarin (Citrus reticulata) in Montenegro, using multilocus sequence analysis of gyrB, rpoD, and gap1 gene sequences. Gene sequences from a collection of 54 reference pathotype strains of P. syringae from the Plant Associated and Environmental Microbes Database (PAMDB) was used to establish a genetic relationship with our isolates obtained from mandarin. Phylogenetic analyses of gyrB, rpoD, and gap1 gene sequences showed that P. syringae pv. syringae causes citrus blast in mandarin in Montenegro, and belongs to genomospecies 1. Genetic homogeneity of isolates suggested that the Montenegrian population might be clonal which indicates a possible common source of infection. These findings may assist in further epidemiological studies of this pathogen and for determining mandarin breeding strategies for P. syringae control.

Splitting effect of photocurrent for $CdIn_2Te_4$ single crystal

  • You, Sang-Ha;Hong, Kwang-Joon
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 하계학술대회 논문집
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    • pp.84-85
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    • 2009
  • The single crystals of p-$CdIn_2Te_4$ were grown by the Bridgman method without the seed crystal. From photocurrent measurements, it was found that three peaks, A, B, and C, correspond to the intrinsic transition from the valence band states of $\Gamma_7(A)$, $\Gamma_6(B)$, and $\Gamma_7(C)$ to the conduction band state of $\Gamma_6$, respectively. The crystal field splitting and the spin orbit splitting were found to be 0.2360 and 0.1119 eV, respectively, from the photocurrent spectroscopy. The temperature dependence of the $CdIn_2Te_4$ band gap energy was given by the equation of $E_g(T)=E_g(0)$ - $(9.43\times10^{-3})T^2$/(2676+T). $E_g(0)$ was estimated to be 1.4750, 1.7110, and 1.8229 eV at the valence band states of A, B, and C, respectively. The band gap energy of $p-CdIn_2Te_4$ at room temperature was determined to be 1.2023 eV.

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Yield Gap Analysis of Mulberry Sericulture in Northwest India

  • Bhatia, Narendra Kumar;Yousuf, Mohammad;Nautiyal, Raman
    • International Journal of Industrial Entomology and Biomaterials
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    • 제27권1호
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    • pp.131-141
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    • 2013
  • At the interface of reducing agricultural income and increasing unemployment in agrarian economy of rural India, this article summarizes and evaluates the state of mulberry sericulture in northwest India, which includes Himachal Pradesh, Punjab, Rajasthan, Uttarakhand, and Uttar Pradesh. In $11^{th}$ plan period (2007-2012), there was an addition of 6 196 ha (217.09 %) of mulberry acreage at annual linier growth rate of 33.44%. However, total silk production could increase only by 54.64 MT (78.57%) at annual linier growth rate of 15.59 %, due to 43.93% (10.82 kg/ha) reduction in silk productivity at negative growth rate of -13.46%, annually. And now, average raw silk productivity in north-western states of India remains at 13.81 kg/ha, which is lower by 452.93 % (76.36 kg) in comparison to the national average of 100.90 kg/ha. Paper summaries the reasons for increasing cocoon yield gap at farmer's level and discuss the ways and means to increase raw silk productivity to improve the livelihood delivery of mulberry sericulture in northwest India.

Bridgman법에 의해 성장된 $CdIn_2Te_4$ 단결정의 가전자 갈라짐에 대한 광전류 연구 (Photocurrent Study on the Splitting of the Valence Band and Growth of $CdIn_2Te_4$ Single Crystal by Bridgman method)

  • 백승남;홍광준
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2003년도 하계학술대회 논문집 Vol.4 No.1
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    • pp.347-351
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    • 2003
  • A p-$CdIn_2Te_4$ single crystal has been grown by the Bridgman method without a seed crystal in a tree-stage vertical electric furnace. From photocurrent measurements, it was found that three peaks, A, B, and C, corresponded to an intrinsic transition due to the band-to-band transition from the valence band states ${\Gamma}_7(A),\;{\Gamma}_6(B),\;and\;{\Gamma}_7(C)$ to the conduction band state ${\Gamma}_6$, respectively. Also, the valence band splitting of the $CdIn_2Te_4$ crystal has been confirmed by photocurrent spectroscopy. The crystal field splitting and the spin orbit splitting were obtained to be 0.2360 and 0.1119 eV, respectively. Also, the temperature dependence of the band gap energy of the $CdIn_2Te_4$ crystal has been driven as the following equation of $E_g(T)\;=E_g(0)\;-\;(9.43\;{\times}\;10^{-3})T^2/(2676\;+\;T)$. In this equation, the Eg(0) was estimated to be 1.4750, 1.7110, and 1.8229 eV at the valence band state A, B, and C, respectively. The band gap energy of the p-$CdIn_2Te_4$ at room temperature was determined to be 1.2023 eV.

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극세 공극 직물 침구가 먼지 양과 집먼지진드기 Allergen에 미치는 효과에 대한 연구 (A Study for the Effects of Fine Gap Fabric Bedding on the Levels of Dust and House Dust Mite Allergens)

  • 김동회
    • Korean Chemical Engineering Research
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    • 제43권1호
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    • pp.136-139
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    • 2005
  • 집먼지진드기에 의한 호흡기 알레르기 질환의 예방 및 치료를 위해 고려할 수 있는 가장 효율적인 방법 가운데 하나는, 항원이 통과할 수 없는 특수 재질의 커버로 직접 침구류를 씌우는 것이다. 따라서 본 연구에서는 특수 커버 사용 후 먼지 양의 감소와 집먼지진드기 allergen 노출에의 감소 정도를 측정하여 특수 커버의 효과를 검증하였다. 본 연구 결과 우리나라의 일반적인 생활환경에서는 특수 커버의 사용이 집먼지진드기 allergen에 대한 노출을 완전히 막아 주지는 못하였다. 그러나 노출되는 양은 감소시킬 수 있었으며 먼지 양이 감소하는 효과도 있었다.

격벽착화기 화약의 충격파와 민감도 분석 (Analysis on Shock Wave and Sensitivity of Explosives in Through-Bulkhead Initiator)

  • 장승교;황정민;백성현
    • 한국추진공학회지
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    • 제21권4호
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    • pp.36-43
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    • 2017
  • 격벽착화기의 최적 설계를 위하여 여폭약에 의해 생성되는 충격파의 감쇄 특성과 수폭약의 민감도에 관하여 연구하였다. 충격파의 감쇄 특성은 레이저 광간섭계인 VISAR를 이용하여 측정한 격벽의 자유 표면 속도로부터 유도하였고 수폭약의 민감도는 SSGT (Small Scale Gap Test) 결과로부터 구하였다. 격벽착화기의 기폭시험을 통하여 SSGT로부터 구한 화약의 민감도가 격벽착화기와 같이 소량의 화약을 사용하는 시스템에는 충격파 지속 시간이 상이하여 적합하지 않다는 것을 밝혀내었다.

Synthesis, Structure, and Magnetic Properties of 1D Nickel Coordination Polymer Ni(en)(ox)·2H2O (en = ethylenediamine; ox = oxalate)

  • Chun, Ji-Eun;Lee, Yu-Mi;Pyo, Seung-Moon;Im, Chan;Kim, Seung-Joo;Yun, Ho-Seop;Do, Jung-Hwan
    • Bulletin of the Korean Chemical Society
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    • 제30권7호
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    • pp.1603-1606
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    • 2009
  • A new 1D oxalato bridged compound Ni(en)(ox)-2$H_2$O, (ox = oxalate; en = ethylenediamine) has been hydrothermally synthesized and characterized by single crystal X-ray diffraction, IR spectrum, TG analysis, and magnetic measurements. In the structure the Ni atoms are coordinated with four oxygen atoms in two oxalate ions and two nitrogen atoms in one ethylenediamine molecule. The oxalate anion acts as a bis-bidentate ligand bridging Ni atoms in cis-configuration. This completes the infinite zigzag neutral chain, [Ni(en)(ox)]. The interchain space is filled by water molecules that link the chains through a network of hydrogen bonds. Thermal variance of the magnetic susceptibility shows a broad maximum around 50 K characteristic of one-dimensional antiferromagnetic coupling. The theoretical fit of the data for T > 20 K led to the nearest neighbor spin interaction J = -43 K and g = 2.25. The rapid decrease in susceptibility below 20 K indicate this compound to be a likely Haldane gap candidate material with S = 1.