• 건축구조
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• v.14 no.3
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• pp.32-43
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• 2007

• Journal of the Society of Naval Architects of Korea
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• v.43 no.4 s.148
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• pp.422-430
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• 2006

The horn and movable parts around the gap of the conventional semi-spade rudder are visualized by high speed CCD camera with the frame rate of 4000 fps (frame per second) to study the unsteady cavity pattern on the rudder surface and gap. In addition, the pressure measurements are conducted on the rudder surface and inside the gap to find out the characteristics of the flow behavior. The rudder without propeller wake is tested at the range of $1.0{\leq}{\sigma}_v\;1.6$ and at the rudder deflection angle of $-8{\leq}{\theta}{\leq}10^{\circ}$. The time resolved cavity images are captured and show strong cavitation around the rudder gap in all deflection angles. As the deflection angle gets larger, the flow separated from the horn surface increases the strength of cavitation. The accelerated flow along the horn decreases its pressure and the separated flow from the horn increases the pressure abruptly. The pressure distribution inside the gap reveals the flow moving from the pressure to suction side. In the negative deflection angle, the turning area on the movable part initiates the flow separation and cavitation on it.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.7
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• pp.2987-2991
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• 2014

Connexin 43 is an important gap junction protein in vertebrates and is known for its tumor suppressive properties. Cx43 is abundantly expressed in the human intestinal epithelial cells and muscularis mucosae. To explore the role of Cx43 in the genesis of human colon cancer, we performed the expression analysis of Cx43 in 80 cases of histopathologically confirmed and clinically diagnosed human colon cancer samples and adjacent control tissue and assessed correlations with clinicopathological variables. Western blotting using anti-Cx43 antibody indicated that the expression of Cx43 was significantly down regulated (75%) in the cancer samples as compared to the adjacent control samples. Moreover, immunohistochemical analysis of the tissue samples confirmed the down regulation of the Cx43 in the intestinal epithelial cells. Cx43 down regulation showed significant association (p<0.05) with the histological type and tumor invasion properties of the cancer. Our data demonstrated that loss of Cx43 may be an important event in colon carcinogenesis and tumor progression, providing significant insights about the tumor suppressive properties of the Cx43 and its potential as a diagnostic marker for colon cancer.

• Journal of Labour Economics
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• v.42 no.1
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• pp.43-72
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• 2019

As a result of decomposing the wage gap between large enterprises and SMEs using Oaxaca's wage gap decomposition method, the total wage gap of supply side factors was 44.2%, and the service years and educational background were the biggest influences. and As a result of decomposing the wage gap by firm size based on demand side factors such as business performance, total wage gap was 44.9%, and the influence on wage gap was in the order of labor productivity, union and outsourcing ratio. The results of this analysis suggest that it is necessary to consider the demand side factors such as business performance and capital structure of supply side companies such as differences in human capital in order to solve wage gap by firm size.

• Toxicological Research
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• v.32 no.3
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• pp.239-243
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• 2016

Propolis is a multicomponent, active, complex resinous substance collected by honeybees from a variety of plant sources. We have studied the effect of propolis on neurite outgrowth of SH-SY5Y human neuroblastoma cells induced to differentiate by all-trans-retinoic acid (RA). Propolis, at a concentration of $3{\mu}g/mL$, had no significant effect on the viability of differentiating SH-SY5Y cells. However, the neurite outgrowth of the differentiating SH-SY5Y cells treated with propolis ($0.3{\sim}3{\mu}g/mL$) for 48 hr was significantly inhibited in a dose-dependent manner. Treatment of RA-stimulated differentiating SH-SY5Y cells with 0.3 to $3{\mu}g/mL$ propolis resulted in decreased level of transglutaminase and 43-kDa growth-associated protein (GAP-43) in a dose-dependent manner. The results indicate that propolis is able to inhibit neurite outgrowth of differentiating SH-SY5Y cells.

• Journal of the Society of Naval Architects of Korea
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• v.43 no.5 s.149
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• pp.578-585
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• 2006

Cavitation related erosion damages on semi-spade rudder generally occur at around leading edge of lower-face and behind gap of lower pintle. To get the idea of gap entrance profile for the latter case, a series of tests with large models has been carried out at MOERI. In the tests, the flow pattern around lower pintle have been investigated and visualized by high speed camera. Additionally, cavitation inception tests and pressure measurements have also been conducted for better comparison. As a result a new model (F rudder) has been developed. The new model turned out to have stable pressure distribution along the surface and so the cavitation inception speeds within ${\pm}5^{\circ}$ of rudder angle were delayed approx. 4 knots in average.

• Journal of Korean Society for Quality Management
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• v.43 no.2
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• pp.127-140
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• 2015

Purpose: To obtain the area for improvement, the Importance-Performance analysis(IPA) uses relatively simple questions, that is, satisfaction and importance at attribute level. However, no attempt has been made to consider the gap between own company's performance and those of competitors in IPA, in the field of quality management. This study is aimed to suggest a new prioritizing method for improvement and to test for validity of the proposed technique. Methods: This study used data collected from Song and Lim(2015), which is satisfaction of employees, customers and competitors as well as importance data for 7 quality attributes of K animal hospital. A correlation comparison with other priority methods such as Bacon(2003)'s model and Matzler and Hinterhuber(1998)'s QI index is conducted. Results: The priority results by the proposed method shows better in correlation coefficient with customer perceived priority for improvement than other methods. Conclusion: From the result of the current study, it can be concluded that the result of the proposed method is valid, while it is relatively easy to understand and analyze, and therefore no additional survey is necessary for improvement priority.

• Journal of Korean Society for Quality Management
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• v.43 no.3
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• pp.397-408
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• 2015

Purpose: Express mail service(EMS) supplied by 'Korea POST'is an international postal service which brings letters, documents and parcels to a destination abroad in the fastest and safest way. This service is in a tough competition with global companies such as TNT, FedEx, DHL or UPS. To build an effective strategy for being competitive, an intensive study on EMS service quality should be accomplished from a customer's perspective. Methods: Kano model and improvement gap analysis are used to categorize and prioritize EMS service quality attributes. A 5-point Lickert scale is employed to apply the Kano model and improvement gap analysis. Each quality attribute can be classified as weak in comparison with competitors, critical for improvement, or potentially competitive. Results: Price, on-time delivery and delivery quality are to be kept as is; fast delivery, parking convenience and staff expertise can be potentially competitive; and the other attributes are considered to be critical for improvement. Conclusions: Fast reimbursement and proper compensation when shipping items are lost or damaged are to be improved with high priority. Efforts to secure fast delivery, parking convenience and staff expertise are needed to be competitive in the future.

• Nuclear Engineering and Technology
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• v.43 no.5
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• pp.447-458
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• 2011

This paper proposes an approximated contact force model to identify the nonlinear behavior of a fuel rod with gap supports; also, the numerical prediction of interfacial forces in the mechanical contact of fuel rods with gap supports is studied. The Newmark integration method requires the current status of the contact force, but the contact force is not given a priori. Taylor's expansion can be used to predict the unknown contact force; therefore, it should be guaranteed that the first derivative of the contact force is continuous. This work proposes a continuous and differentiable contact force model with the ability to estimate the current state of the contact force. An approximated convex and differentiable potential function for the contact force is described, and a variational formulation is also provided. A numerical example that considers the particularly stiff supports has been studied, and a fuel rod with hardening supports was also examined for a realistic simulation. An approximated proper solution can be obtained using the results, and abrupt changes from the contacting state to non-contacting state, or vice versa, can be relieved. It can also be seen that not only the external force but also the developed contact force affects the response.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.3
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• pp.19-39
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• 2008

Objectives : It has been reported that CG was effective in decreasing injury to neural tissues. To investigate neural responses in the injured spinal cord, an extract of CG was examined to determine its effect on neural responses in the injured spinal cords of rats. Methods : After CG treatment was applied to the spinal cord of rats given a contusion injury, the re-growth responses of injured neural tissues and corticospinal tract axons was observed by measuring the number of GAP-43, Cdc2, and phospho-Erk1/2 proteins, CST axons, GFAP-stained astrocytes, and Glial scarring in the injured spinal cord. Results : Levels of GAP-43, Cdc2, and phospho-Erk1/2 proteins were found to have increased in the injured spinal cord region. The number of GFAP-stained astrocytes also increased within and around the injury cavity. Glial scarring, which was identified by CSPG immunofluorescence staining, was reduced by CG treatment. Anterograde tracing by Dil dye showed that the elongation of the CST axons in the dorso-medial white matter area was almost completely prevented at the injury site. Collateral sprouting was observed in the spinal cord rostrally close to the injury site, and CG treatment further increased axonal arborization in the corresponding region. In vivo migration of CST axons and astrocytes using an implanted polymer tube system showed more of an increase in enhanced migration of axons and astrocytes in CG-treated group compared to the injury control group. Conclusions : These results suggest that CG activated neural responses - including astrocyte migration - and promotes axonal regenerative activity in the injured spinal cord area.