• Asian-Australasian Journal of Animal Sciences
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• v.27 no.9
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• pp.1319-1327
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• 2014

Two feeding trials were conducted to determine the optimum feeding frequency in growing Korean rockfish, (Sebastes schlegeli) reared at the temperatures of $15^{\circ}C$ and $19^{\circ}C$. Fish averaging $92.2{\pm}0.7$ g (mean${\pm}$standard deviation [SD]) at $15.0{\pm}0.5^{\circ}C$ and $100.2{\pm}0.4g$ ($mean{\pm}SD$) at $19.0{\pm}0.5^{\circ}C$ water temperature were randomly distributed into each of 15 indoor tanks containing 250-L sea water from a semi-recirculation system. A total of five feeding frequency groups were set up in three replicates as follows: one meal in a day at 08:00 hour, two meals a day at 08:00 and 17:00 hours, three meals a day at 08:00, 14:00, and 20:00 hours, four meals a day at 08:00, 12:00, 16:00, and 20:00 hours, and one meal every 2 days at 08:00 hour. Fish were fed at the rate of 1.2% body weight (BW)/d at $15^{\circ}C$ and 1.5% BW/d at $19^{\circ}C$. At the end of 8 wks of feeding trial weight gain and specific growth rate were significantly higher at the fish fed groups of one meal a day and two meals a day at $15^{\circ}C$ and fish fed groups of 1 meal every 2 days at $19^{\circ}C$ were significantly lower than those of all other fish fed groups. Glutamic oxaloacetic transaminase and glutamic pyruvic transaminase of fish fed group at 1 meal every 2 days was significantly higher than those of all other fish fed groups in both experiments. Weight gain, specific growth rate and condition factor were gradually decreased as the feeding frequency increased. The results indicate that growing Korean rockfish 92 and 100 g perform better at $15^{\circ}C$ than $19^{\circ}C$ water temperature. As we expected, current results have indicated that a feeding frequency of 1 meal a day is optimal for the improvement of weight gain in growing Korean rockfish grown from 92 g to 133 g at $15^{\circ}C$ and 100 g to 132 g at $19^{\circ}C$ water temperature.

• BMB Reports
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• v.51 no.1
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• pp.27-32
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• 2018

Non-small-cell lung cancer (NSCLC) is commonly caused by a mutation in the epidermal growth factor receptor (EGFR) and subsequent aberrant EGFR signaling with uncontrolled kinase activity. A deletion mutation in EGFR exon 19 is frequently observed in EGFR gene mutations. We designed a DNAzyme to suppress the expression of mutant EGFR by cleaving the mutant EGFR mRNA. The DNAzyme (named Ex19del Dz) specifically cleaved target RNA and decreased cancer cell viability when transfected into gefitinib-resistant lung cancer cells harboring EGFR exon 19 deletions. The DNAzyme decreased EGFR expression and inhibited its downstream signaling pathway. In addition to EGFR downregulation, Ex19del Dz containing CpG sites activated Toll-like receptor 9 (TLR9) and its downstream signaling pathway via p38 kinase, causing an immunostimulatory effect on EGFR-mutated NSCLC cells. Thus, dual effects of this DNAzyme harboring the CpG site, such as TLR9 activation and EGFR downregulation, leads to apoptosis of EGFR-mutated NSCLC cells.

• Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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• 2003.04a
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• pp.100-100
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• 2003

키토산처리가 콩나물의 성장특성에 미치는 영향을 조사하기 위하여 콩에 0.05% 키토산(493kDa, 금호화성, 한국)을 함유하는 0.05% 초산 용액 4배량을 가하여 8시간 침지한 후 2$0^{\circ}C$에서 2시간 간격으로 5일간 주수하면서 발아율, 수율, 배축과 자엽의 중량변화, 수분함량, 배축의 길이와 두께 등을 조사하였다. 발아율은 키토산처리구(88-94%)가 대조구(69-85%) 보다 높았다. 5일간 재배한 콩나물의 생체중량은 처리구(70.28 g/10 g-pot)가 대조구(63.86 g/10 g-pot) 보다 18% 높았다. 재배중의 수분함량은 대조구(59.53-73.33%) 보다 처리구(64.66-84.45%)가 5.13-11.12%가 높았다. 재배중의 자엽의 중량은 대조구(25.06-27.21 g/10 g-pot)가 처리구(23.42-25.55 g/10 g-pot) 보다 높았으며 배축의 중량은 대조구(9.27-36.25 g/10 g-pot)보다 처리구(15.19-44.73 g/10 g-pot)가 높았다. 재배중 배축의 길이와 두께는 대조구(6.51-19.87 cm)보다 처리구(7.67-22.38 cm)가 길었으며, 두께는 대조구(2.08-2.12 mm)가 처리구(203-2.08 mm)보다 약간 두꺼웠다. 이상의 결과 키토산처리는 콩나물의 발아율을 높이며, 콩나물의 수분함량이 높고, 배축의 길이가 기나 두께는 다소 가는 특성을 나타내었다.

• 한국해양학회지
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• v.21 no.3
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• pp.125-130
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• 1986

The concentrations of Cu, Pb and Zn in the surface waters of Kwangyang Bay were determined bimonthly at 20 stations during 1983-84. The ranges and mean concentrations were 〈0.03-2.68$\mu\textrm{g}$/l, 1.08$\mu\textrm{g}$/l for Cu, 〈0.03-7.19$\mu\textrm{g}$/l, 0.76$\mu\textrm{g}$/l for Pb and 0.3-23.1$\mu\textrm{g}$/l, 5.6$\mu\textrm{g}$/l for Zn, respectively. The slightly higher levels of heavy metals studied were shown in Sueo and Seomjin River Estuaries. Analysis of correlation coefficients showed that Cu, Pb and Zn were closely associated not only to one another nut also to SS and COD in seawater.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.66 no.4
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• pp.428-434
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• 2021

To study whether the area under the cultivation of Italian ryegrass (IRG) has increased with rise in global temperatures, we investigated the effects of climatic variables on seed productivity in different parts of Gangwon-do, South Korea. Specifically, IRG was cultivated in the western (Gangneung), central (Wonju), and northern (Chuncheon) parts of Gangwon-do. The heading date of IRG in Gangneung was earlier than that in the other regions. Moreover, the values of agronomic traits, including spikelets per spike, grains per spike, and thousand-grain weight, were lower in Chuncheon. However, there were no differences spikelets per spike and grains per spike between Wonju and Gangneung. Additionally, the thousand-grain weight and seed production were higher in Gangneung. Statistical correlation analysis between climatic variables and agronomic traits revealed that the mean daily minimum temperature was positively correlated with seed formation-related traits in April and seed maturity-related traits in May. In the light of rising minimum temperatures in Gangwon-do, Gangneung, Chuncheon and Wonju are suitable areas for IRG cultivation with optimal seed productivity.

• Journal of Mushroom
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• v.19 no.4
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• pp.322-328
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• 2021

This study was carried out to evaluate potential of Hypsizygus marmoreus (brown cultivar) as a functional food and drug materials. H. marmoreus were divided into pileus and stipe and extracted in hot water and 80% ethanol. The total polyphenol content was highest in the hot water extracts (pileus 17.15±0.19 mg of GAE g, stipe 7.37±0.16 mg of GAE/g) and pileus compared to the ethanol extracts (pileus 10.23±0.14 mg of GAE/g, stipe 3.76.±0.19 mg of GAE/g) and stipe. Also, hot water extracts of pileus from H. marmoreus (brown cultivar) was more effective DPPH, ABTS, ORAC value, reducing power than ethanol extracts and stipe extracts. The pileus and stipe extracts were confirmed to be non-cytotoxic in the mouse macrophage cell line RAW 264.7 determined by WST-1 (4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulphonate) assay. Overall, extracts of H. marmoreus (brown cultivar) was higher antioxidant activity than other mushrooms, and no cytotoxicity. Therefore, H. marmoreus (brown cultivar) showed potential as a functional food and drug materials. The brown cultivar of H. marmoreus have higher antioxidant activity than white cultivar, H. marmoreus seem to have different antioxidant activity depending on the cultivar.

• The Plant Pathology Journal
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• v.19 no.6
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• pp.274-279
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• 2003

Two Gymnosporangium species, G. japonicum and G. cornutum, causing cedar-apple rust, were newly identified in Korea, and a new aecial host for each fungus was found by artificial inoculation. Detailed descriptions of the species were made based on macroscopic features (symptoms and signs) and light and scanning electron microscopic observations of spores and peridial cells. G. japonicum from Juniperus chinensis var. horizontalis had Photinia villosa as its new aecial host G. cornutum from J. rigida showed its aecial stage on Sorbus alnifolia.

• Journal of environmental and Sanitary engineering
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• v.11 no.3
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• pp.9-12
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• 1996

Polychlorinated biphenyl (PCBs) is one of major toxic pollutants in marine environments, This artificial chlorinated compound has been found in freshwater, seawater, soil, sediments and organismes living in various environments. Because of its toxicity and degradability, its uses in industrial processes have been banned after 1984 in Korea. Coastal area is an important environment for agriculture, industry, transportation, reduction of pollution loads through biogeochemical processes, cycling of nutrients and recreation. Input of pollutants from land and freshwater has been occurring through runoff, rivers and estuaries. Concentrations of PCBs were determined with GC-ECD. Concentrations of PCBs were in the range of 1.0 - 19.2 ng/g-dry weight of sediment(g-d.w.) at Ulsan, 4.5 -8,2 ng/g-d.w. at Onsan, 2.7 - 33.5 ng/g-d.w. at Masan and 4.0 - 60.7 ng/g-d.w. in Kwangyang, In Inchon area, PCBs were not detected in sediments. In sediments of Nakdong estuary, the distribution of PCBs' concentrations was 0.19 - 303 ng/g-d.w.

• Carbon letters
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• v.16 no.1
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• pp.19-24
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• 2015

The breakthrough behaviour of activated charcoal cloth samples against an oxygen analogue (OA) of sulphur mustard has been studied using the modified Wheeler equation. Activated charcoal cloth samples having different surface area values in the range of 481 to $1290m^2/g$ were used for this purpose. Breakthrough behaviour was found to depend on the properties of the activated charcoal cloth, properties of the OA and the adsorption conditions. Activated charcoal cloth with a high surface area of $1290m^2/g$, relatively large surface density of $160g/m^2$ and coarser fiber structure exhibited better kinetic saturation capacity value, 0.19 g/g, against OA vapours when compared to others, thus confirming its potential use in foldable masks for protection against chemical warfare agents.

• Biomedical Science Letters
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• v.18 no.1
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• pp.71-75
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• 2012

The PLA2G4A catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid, which is metabolized into lipid-based cellular hormones that regulate inflammatory response. The circulating blood cell numbers can be influenced by stress, infection or inflammation. Quantitative blood cell count traits analysis for the 19 SNPs in the PLA2G4A gene in the Korean Association Resource (KARE) cohort (7551 subjects) was performed. The only one SNP (rs10752979) in the all blood cell count was satisfied with the Bonferroni corrected P-value (<0.00263). Furthermore, 6 of the 19 SNPs in the PLA2G4A gene showed a weak or moderate association with blood cell count (P-values: 0.0048~0.042), suggesting the clue of an association between the PLA2G4A gene and blood cell count, especially white blood cell count. This study may provide insight into the genetic basis of blood cell count related with reaction of infection.